EKS-GAG-00169

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-GAG-00169

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
AGC/MAST	529.6	1.8E-159	350	623	274

Status

Unreviewed

Ensembl Protein

ENSGALP00000023805

UniProt Accession

F1N8Z9;

Protein Name

Protein Synonyms/Alias

Gene Name

LOC427170

Gene Synonyms/Alias

LOC427170;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSGALG00000014784	ENSGALP00000023805	ENSGALT00000023851
ENSGALG00000014784	ENSGALP00000023813	ENSGALT00000023859

Organism

Gallus gallus

Functional Description

Protein Length

1324

Protein Sequence
(FASTA)

SCRTSNRKSL MGNGQSPALP RPHSPLSAHT GNSPQDSPRN FSPSASAHFS FARSFHNRTD 60

GRRWSLASLP SSGYGTNTPS STVSSSCSSQ EKLHQLPYQP TPDELHFLSK HFCTTESIAS 120

DNRCRTTAMR PRSRSLSPGR SPACCNNEII MMNHVYKERF PKATAQMEER LQDIITNHSP 180

ENVLPLADGV LSFTHHQITE LARDCLDKSH QGLITSRYFL ELQQKLDKLL QEAQERSESE 240

ELAYIKQLVR KILIVIARPA RLLECLEFDP EEFYYLLEAA EGHAKEGQGI KTDIPRYIIS 300

QLGLNKDPLE EIAQLANCDS GTAETLEMDE SVTSSNTSLQ LRRKPRESDF ETIKLISNGA 360

YGAVYFVRHK ETRQRFAMKK INKQNLILRN QIQQAFVERD ILTFAENPFV VSMYCSFETR 420

RHLCMVMEYV EGGDCATLMK NMGPLPVDMA RMYFAETVLA LEYLHNYGIV HRDLKPDNLL 480

VTSMGHIKLT DFGLSKVGLM SLTTNLYEGH IEKDAREFLD KQVCGTPEYI APEVILRQGY 540

GKPVDWWAMG IILYEFLVGC VPFFGDTPEE LFGQVISDEI NWPEKDEAPP PDAQDLITLL 600

LRQNPLERLG TGGAYEVKQH KFFRSLDWNS LLRQKAEFIP QLESEDDTSY FDTRSEKYHH 660

METEEEDDTN DEDFNLEIRQ FSSCSHRFSK VSKNCYSVNT HKFISVLSAP NCIDRVSQTQ 720

GDEKEDAGDK TKSVALPSVE SLSWSSEYSE IQQVSTSISS DTESSRQRHS SGLLPKLAIS 780

AEGEQDDSTC LVGAQEEPEK PPLVSEEIVQ DEPEVTTPAS TISSSTLSGN SHCMNGRSES 840

VDSTDNSSKP PTEVAFQMAR QRLESTEKKK ISGKVTKSLS ASALSLMIPG GRDVFGVSPL 900

GSPMSPHSLS SDPSSSRDSS PSRESSIAAA SPHQPVVIHS SGKKYGFTIR AIRVYVGDSD 960

IYTVHHIVWN VEEGGAAYQA GLKAGDLITH INGEPVHGLV HTEVIELLLK SGNKVSIMTT 1020

PFENTSIKTG PARKNSYRSR MVRRSKKTKK KESLERLCSS HTRRRSLFKK LAKQPSPLLH 1080

TSRSFSCLNR SLSSGESLPG SPTHSLSPRS PTPSYRSTPD FPSGTNSSQS SSPSSSAPNS 1140

PAGSGHIRPS TLHGLGPKLS GQRYRSGRRK SAGSIPLSPL ARTPSPTPQP TSPQRSPSPL 1200

LGHSIGSTKI AQSFPSKMHS PPTIVRHIVR PKSAEPPRSP LLKRVQSEEK LAPSYASDKK 1260

HLCSRKHSLE VTQEEVNREL SQREVTLQSL EENVCDVPSL TRVRPAEQGC LKRPISRKLG 1320

RQES 1324

Nucleotide Sequence
(FASTA)

AGCTGTAGAA CAAGCAATCG AAAGAGTTTG ATGGGCAATG GCCAGTCTCC AGCTCTGCCT 60

CGACCTCATT CACCTCTCTC AGCACACACA GGAAACAGTC CTCAAGATAG TCCTAGGAAT 120

TTCTCTCCCA GTGCCTCAGC CCACTTTTCC TTTGCAAGAA GTTTTCACAA CAGGACTGAT 180

GGTCGCCGCT GGTCTTTGGC TTCCCTCCCT TCTTCTGGTT ATGGTACAAA TACACCCAGC 240

TCAACTGTTT CTTCATCTTG TTCATCACAA GAGAAACTAC ACCAGTTACC ATACCAGCCA 300

ACACCTGATG AACTACATTT TTTATCTAAA CATTTCTGTA CCACTGAAAG CATTGCAAGC 360

GATAACAGAT GCAGGACCAC GGCAATGCGC CCTCGCTCCA GAAGTCTCAG TCCCGGACGT 420

TCTCCTGCCT GCTGTAACAA TGAGATAATT ATGATGAACC ATGTCTACAA GGAAAGGTTC 480

CCAAAGGCCA CAGCCCAGAT GGAAGAAAGG CTGCAGGACA TTATAACAAA TCATTCTCCA 540

GAAAACGTCC TTCCGCTGGC AGATGGTGTA CTCAGTTTTA CCCACCATCA GATCACAGAA 600

CTGGCTCGAG ATTGTTTGGA TAAATCCCAC CAGGGCCTCA TCACATCTCG ATACTTCCTT 660

GAATTACAAC AGAAATTAGA CAAGTTGCTA CAGGAGGCCC AGGAGCGATC AGAGAGTGAA 720

GAACTGGCGT ATATCAAGCA ACTAGTTAGA AAAATCCTCA TAGTCATTGC TCGTCCTGCT 780

CGTTTACTGG AATGCCTGGA ATTTGATCCA GAAGAGTTTT ACTATCTTTT GGAAGCAGCT 840

GAAGGCCATG CTAAAGAGGG ACAAGGCATT AAAACAGACA TTCCCCGCTA CATTATTAGT 900

CAGCTGGGCT TAAATAAAGA TCCTCTGGAA GAAATAGCTC AACTAGCTAA CTGTGACAGT 960

GGGACAGCAG AAACTCTGGA AATGGATGAA TCAGTAACTA GCTCTAATAC CTCACTACAG 1020

CTCCGGAGAA AACCTCGAGA AAGTGATTTT GAAACAATTA AACTGATTAG TAATGGAGCT 1080

TATGGTGCGG TTTATTTTGT GAGACATAAA GAAACCAGAC AAAGATTTGC CATGAAGAAG 1140

ATTAATAAGC AGAATCTCAT CCTTCGAAAC CAGATCCAAC AGGCCTTCGT CGAGCGTGAT 1200

ATCCTGACAT TTGCAGAAAA CCCTTTTGTT GTCAGCATGT ATTGTTCTTT TGAAACAAGA 1260

CGTCACTTAT GTATGGTCAT GGAATACGTA GAAGGTGGAG ACTGTGCTAC TTTGATGAAA 1320

AATATGGGCC CCTTACCTGT GGACATGGCA AGGATGTATT TTGCAGAGAC TGTTCTGGCC 1380

TTGGAATACC TTCATAATTA TGGAATTGTA CACAGAGATT TGAAGCCAGA TAATTTATTG 1440

GTAACATCCA TGGGCCATAT AAAGCTTACA GACTTCGGTC TGTCAAAGGT GGGGCTAATG 1500

AGTTTGACTA CCAATCTATA TGAGGGTCAC ATTGAGAAGG ATGCCAGAGA ATTCCTTGAT 1560

AAACAAGTTT GTGGTACACC TGAATACATA GCTCCTGAAG TAATACTGAG ACAGGGTTAT 1620

GGAAAACCAG TGGACTGGTG GGCTATGGGA ATTATTCTTT ATGAATTTCT TGTTGGGTGT 1680

GTGCCGTTCT TTGGAGATAC ACCAGAAGAG CTGTTTGGAC AAGTAATCAG TGATGAAATC 1740

AACTGGCCTG AAAAGGATGA AGCACCGCCT CCAGATGCTC AGGATCTCAT TACCCTGCTG 1800

CTCAGGCAGA ATCCCTTGGA AAGATTGGGA ACAGGTGGTG CATATGAAGT AAAGCAACAT 1860

AAGTTCTTCA GGAGCCTTGA CTGGAACAGT CTGCTAAGAC AGAAAGCAGA GTTTATTCCA 1920

CAGTTGGAGT CTGAAGATGA CACAAGTTAT TTTGACACTC GTTCTGAGAA ATACCACCAT 1980

ATGGAAACTG AGGAAGAAGA TGATACAAAT GATGAAGATT TTAATTTGGA GATAAGACAG 2040

TTTTCCTCAT GTTCACACAG ATTTTCAAAA GTAAGTAAAA ATTGCTATAG CGTTAATACG 2100

CATAAATTCA TTTCTGTGCT TTCTGCACCT AACTGCATAG ACCGAGTTTC TCAAACACAA 2160

GGTGATGAAA AGGAAGATGC AGGAGACAAA ACAAAAAGTG TAGCATTGCC CTCAGTGGAA 2220

TCTTTAAGCT GGAGCTCAGA ATATTCTGAA ATACAACAAG TATCTACATC CATCTCCTCT 2280

GACACCGAGA GTAGCAGGCA GCGACATAGT TCTGGTTTGT TGCCAAAGCT GGCCATATCT 2340

GCCGAAGGAG AACAAGATGA TTCCACCTGC TTAGTGGGAG CACAGGAGGA GCCGGAAAAG 2400

CCTCCATTAG TGAGTGAAGA AATAGTACAA GACGAACCCG AAGTAACAAC TCCAGCAAGT 2460

ACAATCAGCA GCTCCACACT GTCAGGTAAT TCACACTGTA TGAATGGACG AAGCGAAAGT 2520

GTGGACAGCA CGGATAACTC CTCAAAGCCT CCCACTGAAG TTGCATTTCA GATGGCTCGA 2580

CAGAGATTAG AAAGTACAGA GAAAAAGAAG ATCTCTGGAA AAGTTACAAA GTCTCTTTCT 2640

GCAAGTGCTT TGTCCCTCAT GATCCCAGGA GGTAGAGATG TGTTTGGTGT TTCTCCTTTG 2700

GGAAGTCCAA TGTCTCCTCA TTCGCTGTCA TCTGATCCTT CGTCCTCTCG GGATTCCTCT 2760

CCTAGTCGTG AGTCTTCAAT TGCTGCTGCA AGTCCTCATC AGCCTGTAGT AATTCACAGT 2820

TCAGGAAAAA AGTATGGCTT CACCATCCGA GCAATCAGGG TTTATGTGGG AGACAGTGAT 2880

ATTTACACTG TGCACCATAT TGTTTGGAAT GTGGAAGAAG GAGGCGCAGC ATACCAAGCT 2940

GGTTTGAAAG CTGGGGACCT AATTACTCAT ATCAATGGAG AGCCTGTGCA TGGTCTTGTT 3000

CATACAGAAG TCATTGAGTT GTTGTTAAAG AGTGGCAACA AAGTGTCAAT TATGACAACA 3060

CCTTTTGAAA ACACTTCCAT CAAGACAGGA CCTGCCAGGA AAAACAGCTA CAGGAGCCGA 3120

ATGGTCAGGC GCAGTAAGAA AACCAAGAAG AAAGAGAGTT TAGAGAGGCT TTGCTCTTCC 3180

CACACTAGGA GGAGGTCTCT CTTTAAAAAG TTGGCCAAGC AGCCCTCTCC TCTTCTTCAC 3240

ACCAGCAGAA GTTTCTCCTG CCTGAACCGA TCCCTTTCAT CAGGGGAGAG CTTACCTGGA 3300

TCTCCAACTC ACAGCTTGTC TCCAAGATCA CCTACCCCAA GCTACCGTTC CACTCCTGAT 3360

TTTCCATCTG GTACTAATTC TTCTCAGAGT AGCTCCCCTA GTTCGAGTGC TCCCAATTCT 3420

CCAGCTGGTT CAGGACACAT AAGACCCAGC ACTCTTCATG GCTTGGGCCC AAAGCTTAGC 3480

GGGCAAAGAT ACAGATCTGG AAGACGCAAA TCAGCTGGCA GCATTCCTCT CTCTCCTTTG 3540

GCAAGAACGC CTTCCCCGAC ACCGCAGCCC ACATCACCTC AGCGATCTCC ATCACCATTG 3600

CTAGGGCATT CAATTGGGAG TACGAAGATA GCTCAGTCTT TTCCTAGCAA GATGCACTCC 3660

CCTCCAACTA TTGTAAGACA TATTGTTAGG CCGAAAAGCG CAGAACCACC ACGATCTCCT 3720

CTCTTAAAGA GAGTCCAGTC TGAAGAGAAA CTTGCACCCT CTTATGCTAG TGATAAGAAA 3780

CACTTATGTT CACGAAAACA CAGTCTTGAA GTGACTCAGG AAGAAGTGAA TAGAGAATTG 3840

TCCCAAAGGG AAGTAACTCT TCAGAGCTTG GAGGAGAATG TGTGTGATGT ACCATCACTT 3900

ACACGAGTCA GACCTGCTGA GCAGGGCTGC TTGAAACGGC CCATCTCCCG AAAATTAGGT 3960

AGGCAAGAAT CC 3972

Domain Profile

S: 1     feiiklisrGayGavylvrhketrkrfavkkikkqdlilknqvqqvfaerdilalaenpf  60

         fe+iklis+GayGavy+vrhketr+rfa+kki+kq+lil+nq+qq+f+erdil++aenpf

Q: 350   FETIKLISNGAYGAVYFVRHKETRQRFAMKKINKQNLILRNQIQQAFVERDILTFAENPF  409

         99**********************************************************

S: 61    vvslyysletrrnlylvmeyveGGdvksllkniGaldvemarlyiaevvlaleylhryGi  120

         vvs+y+s+etrr+l++vmeyveGGd+++l+kn+G+l+v+mar+y+ae+vlaleylh+yGi

Q: 410   VVSMYCSFETRRHLCMVMEYVEGGDCATLMKNMGPLPVDMARMYFAETVLALEYLHNYGI  469

         ************************************************************

S: 121   vhrdlkPdnllitseGhikltdfGlskvglmslttnlyegyidkdarefldkqvcgtPey  180

         vhrdlkPdnll+ts+GhikltdfGlskvglmslttnlyeg+i+kdarefldkqvcgtPey

Q: 470   VHRDLKPDNLLVTSMGHIKLTDFGLSKVGLMSLTTNLYEGHIEKDAREFLDKQVCGTPEY  529

         ************************************************************

S: 181   iaPevilrqgygkpvdwwalgiilyeflvgivpffgdtpeelfaqvlsdeivwPekdeal  240

         iaPevilrqgygkpvdwwa+giilyeflvg+vpffgdtpeelf+qv+sdei+wPekdea

Q: 530   IAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVISDEINWPEKDEAP  589

         ************************************************************

S: 241   ssealelisellesnPrerlgtgsaaevkqhefl  274

         +++a++li+ ll++nP erlgtg+a+evkqh+f+

Q: 590   PPDAQDLITLLLRQNPLERLGTGGAYEVKQHKFF  623

         ********************************97

Domain Sequence
(FASTA)

FETIKLISNG AYGAVYFVRH KETRQRFAMK KINKQNLILR NQIQQAFVER DILTFAENPF 60

VVSMYCSFET RRHLCMVMEY VEGGDCATLM KNMGPLPVDM ARMYFAETVL ALEYLHNYGI 120

VHRDLKPDNL LVTSMGHIKL TDFGLSKVGL MSLTTNLYEG HIEKDAREFL DKQVCGTPEY 180

IAPEVILRQG YGKPVDWWAM GIILYEFLVG CVPFFGDTPE ELFGQVISDE INWPEKDEAP 240

PPDAQDLITL LLRQNPLERL GTGGAYEVKQ HKFF 274

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Equus caballus"; ?>Felis catus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Tetraodon nigroviridis"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0000287	; F:magnesium ion binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR000961	; AGC-kinase_C.
IPR011009	; Kinase-like_dom.
IPR015022	; MA_Ser/Thr_Kinase_dom.
IPR023142	; MAST_pre-PK_dom.
IPR001478	; PDZ.
IPR000719	; Prot_kinase_cat_dom.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF08926	; DUF1908; 1.
PF00595	; PDZ; 1.
PF00069	; Pkinase; 1.

SMARTs

SM00228	; PDZ; 1.
SM00133	; S_TK_X; 1.
SM00220	; S_TKc; 1.

Prosites

PS51285	; AGC_KINASE_CTER; 1.
PS50106	; PDZ; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013