EKS-GAG-00060

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-GAG-00060

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
TK/Sev	479.4	3.3E-144	1958	2229	272

Status

Unreviewed

Ensembl Protein

ENSGALP00000024005

UniProt Accession

F1NQL9;

Protein Name

Tyrosine-protein kinase receptor

Protein Synonyms/Alias

Gene Name

ROS1

Gene Synonyms/Alias

ROS1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSGALG00000014913	ENSGALP00000036566	ENSGALT00000037359
ENSGALG00000014913	ENSGALP00000036565	ENSGALT00000037358
ENSGALG00000014913	ENSGALP00000024005	ENSGALT00000024051

Organism

Gallus gallus

Functional Description

Protein Length

2262

Protein Sequence
(FASTA)

MRNACLLLNR LGAFYFIWIS AAYCSFSKNC QDLCTSNLKC DFKVFLSQHL SLQCTQGCQF 60

WNATEQVNCP LKCNKTYTRE CETVSCKFGC SRAEDAYGVE AQNCLNKPGA PFASSIGSHN 120

ITLGWKPANI SEVKYIIQWK FHQLPGDWRY TEVVSETSYT VKDLQAFTEY EFRVVWIITS 180

QLQLHSPPSP SYRTHASGVP TTAPIIKDIQ SSSPNTVEVS WFPPLFPNGL IVGYNLVLTS 240

ENHELLRASR GHSFQFYSTF PNSTYRFSIV AVNEAGAGPP AEANITTPES KVKEKAKWLF 300

LSRNQSLRKR YMEHFLEAAH CLQNGIIHHN ITGISVNVYQ QVVYFSEGNS IWVKGVVDMS 360

DVSDLTLFYT GWGNITSISV DWLYQRMYFV MNEKIHVCQL ENCTAAEDIT PPYVTSPRKI 420

VADPYNGYIF CLLEDGIYRA NLPLFPDTAS AASLVVKSHT LRDFMINFQS KRLIFFNKTE 480

QAFVSGFLDG SEFHTLRAHV PLDDMESFVY EDNIFTVTDG RAVFHEEISQ VGSSSFNEYV 540

VDCSLEYPEY FGFGNLLFYA ASTQPYPLPT LPRLVTVLFG SDQAVISWSP PEYTIGTSRS 600

AWQNWTYDVK VSSQSTFEEE WVVSNITDTR FAVKNLVSFT EYEMSVRAVS PAGEGPWSEP 660

FRGMTFEEAE EEPYILAVGA EGLWKQRLDS YGPGEFLYPH IRNISDLDWY NDTLYWSNSM 720

GKVQTWSMNK KEGTTENSYV PDIKNARMLA FDWLGQCLYW AGKANTIYRK SLLGDHMDVV 780

AHVVYVVKDL AVDSVNGYLY WATTYTVESA RLNGEEYLIL QEHLQFSGKQ VVGLALDLTS 840

GFLYWLVQDG LCLNLYRISI CKESCGNIMV TEISAWSVSE VSQNALQYYS GRLFWINRLK 900

FITTQELNQS ISIPFSEPAE FAAFTLVHTS LKPLPGNFSF TPKVIPSSVP ESSFKIKGNS 960

SSFHIIWNAS TDVQWGTVFY CVGSNALQTL ESERCLHPHD LTVPSYKVDW LEPFTLFDFS 1020

VTPYTYWGKA PTTSVYLRAP EAVPSAPANP RIYVLHSNTH EGEEKVLVEL RWDKPERDNG 1080

VLTQFRVYYQ LLYESGAADT LMEWNVSDVK PTALLFSIRD VHPRLTVRFQ VQAFTSVGPG 1140

PMSDVAQRNS SDIFPVPTLI TFSSNKLFLT DIDSNHTIWE VLTNRNIKDI CYTADDDKVY 1200

YILEDSLFLL NVQSTSESQL FEDVFLRNVT AITVDWIARH LFVAMKTSWN ETQVFFIDLE 1260

LKTKSLKALN IQLGKRNSTI SSLLSYPFLS RLYWIEELDY GSRMFYYDIL NNTMYHILGY 1320

ESVEEKMRNY CNCNVAEAEL GRPISIDVTD IKKPQLLFIR GRDEIWASDV DGCHCWRITK 1380

IPSFQGTKIG SLTVDKQFIY WTIEKKEYTE ICLADKESTR HSLQRKANHE LKILAYSSAM 1440

QSYPDKKCLT PLLDTEKPTI LDTTNTSFTL SLPSVTTQQL CPSISQPTPT YLVFFREITS 1500

NHENSTYHFS TLLQKTLEIQ EPIAVINNLK PFSSYAIQVA VKNYYSNQNQ LAVGRETIST 1560

TLYGVPEGVD SIKTVVLSDT TINISWSEPL EPNGPLESIR YQISVNLLSL FPEAPLRKSE 1620

FPNGTLSWSV SDLQSGTNNL FKVLAFHPNE NWFSESVPVI AKTFETPLSP SNIIPRNTSF 1680

QLEWRAPLHI NGTSFWFELR KWQTRSDWFS PASTTCTVGP VYTCNLTGTL PSANYLVRAT 1740

VVYVTGMKST SSPTSFKTTA KAGVPSKPGT PKRAEDSKNS VQWEKAEDNG SNLTYYILES 1800

RKQSGNTNKV KSLWVVVYNG SCDSICTWKA ENLEGTFQFR AAAANMLGLG EYSDTSKDIV 1860

LAKDTVTSPD ITAIVAVIGA VVLGLTIIIL FGFVWHQRWK SRKPASTGQI VLVKEDKELA 1920

QLRGMAETVG LANACYAVST LPSQAEIESL PAFPRDKLNL HKLLGSGAFG EVYEGTALDI 1980

LADGSGESRV AVKTLKRGAT DQEKSEFLKE AHLMSKFDHP HILKLLGVCL LNEPQYLILE 2040

LMEGGDLLSY LRGARKQKFQ SPLLTLTDLL DICLDICKGC VYLEKMRFIH RDLAARNCLV 2100

SEKQYGSCSR VVKIGDFGLA RDIYKNDYYR KRGEGLLPVR WMAPESLIDG VFTNHSDVWA 2160

FGVLVWETLT LGQQPYPGLS NIEVLHHVRS GGRLESPNNC PDDIRDLMTR CWAQDPHNRP 2220

TFFYIQHKLQ EIRHSPLCFS YFLGDKESVA GFINQAFEGK PG 2262

Nucleotide Sequence
(FASTA)

ATGAGGAACG CTTGCCTGCT GCTGAACAGA CTTGGTGCTT TTTACTTCAT TTGGATTTCT 60

GCTGCATATT GTTCTTTCTC AAAAAATTGT CAAGACCTAT GTACAAGTAA CCTGAAATGT 120

GACTTCAAAG TCTTTTTAAG CCAACATCTA TCTTTGCAGT GTACACAGGG ATGTCAGTTT 180

TGGAATGCAA CAGAGCAAGT CAATTGCCCA CTGAAATGTA ACAAGACATA CACCAGAGAA 240

TGTGAGACAG TTTCCTGCAA GTTTGGCTGT AGTCGTGCAG AGGATGCATA TGGTGTTGAA 300

GCACAGAACT GTTTGAACAA GCCTGGAGCA CCATTTGCAT CCTCCATTGG AAGCCACAAT 360

ATCACACTGG GTTGGAAGCC AGCTAATATC TCTGAGGTTA AATATATTAT CCAGTGGAAG 420

TTTCATCAGC TCCCTGGAGA CTGGAGATAC ACAGAGGTCG TATCTGAAAC TTCATATACA 480

GTCAAGGACC TTCAAGCCTT CACAGAGTAT GAGTTTCGAG TAGTTTGGAT CATAACCTCT 540

CAGCTGCAGC TCCATTCTCC ACCAAGTCCC AGTTACCGGA CCCATGCTTC TGGAGTTCCT 600

ACTACAGCTC CCATCATTAA AGATATTCAG AGTTCAAGTC CAAACACTGT TGAAGTTAGT 660

TGGTTTCCAC CACTTTTTCC CAATGGATTG ATTGTTGGAT ACAACTTGGT CCTGACCAGT 720

GAGAATCATG AACTGTTGAG AGCATCGAGA GGGCACAGCT TTCAGTTCTA CTCTACCTTC 780

CCAAACAGCA CTTACAGGTT CAGTATTGTA GCTGTTAATG AGGCTGGAGC TGGACCCCCT 840

GCAGAAGCCA ACATCACAAC ACCGGAATCC AAAGTTAAGG AAAAAGCAAA ATGGCTCTTT 900

CTATCCAGAA ACCAGTCTTT AAGGAAAAGA TACATGGAAC ATTTCCTTGA AGCAGCCCAC 960

TGTCTGCAAA ATGGTATAAT ACACCACAAC ATTACAGGAA TTTCTGTGAA TGTTTATCAG 1020

CAAGTTGTCT ATTTTTCTGA GGGGAATTCC ATCTGGGTGA AAGGAGTTGT GGATATGTCT 1080

GATGTATCTG ACTTAACACT CTTTTATACT GGCTGGGGGA ACATTACATC AATCTCAGTA 1140

GATTGGCTTT ACCAGAGGAT GTACTTTGTC ATGAATGAAA AGATACATGT TTGTCAGTTA 1200

GAGAACTGCA CAGCAGCTGA AGACATCACT CCTCCTTATG TGACATCTCC TAGGAAGATT 1260

GTAGCTGATC CCTATAATGG GTATATTTTC TGTCTTCTGG AGGATGGTAT ATACAGAGCA 1320

AACCTTCCAC TCTTTCCTGA CACTGCCTCA GCAGCTTCAC TAGTTGTGAA ATCCCACACT 1380

TTGAGAGACT TCATGATCAA CTTCCAGTCT AAGAGACTCA TTTTCTTCAA CAAAACAGAA 1440

CAGGCCTTTG TGTCGGGTTT TCTTGATGGT TCAGAATTTC ACACTCTGCG AGCACACGTG 1500

CCACTTGATG ACATGGAGAG CTTTGTTTAT GAGGATAACA TATTTACTGT CACAGATGGC 1560

CGGGCAGTTT TCCATGAGGA GATCTCACAA GTGGGAAGTT CTAGCTTCAA TGAGTATGTT 1620

GTAGATTGCA GTTTGGAATA TCCAGAGTAT TTTGGCTTTG GCAATTTGCT TTTCTATGCA 1680

GCATCAACTC AGCCTTATCC TTTACCAACT CTTCCTCGGC TTGTGACAGT ACTCTTTGGA 1740

TCGGATCAAG CTGTGATCAG CTGGAGTCCA CCTGAATACA CAATTGGAAC CAGTCGGTCT 1800

GCTTGGCAGA ACTGGACCTA TGATGTGAAA GTGTCATCTC AAAGTACTTT TGAGGAGGAA 1860

TGGGTTGTCT CAAACATTAC TGACACCAGG TTTGCCGTGA AGAATCTGGT CAGCTTCACA 1920

GAGTATGAGA TGTCAGTCAG AGCCGTGTCT CCTGCTGGTG AAGGACCATG GTCAGAGCCA 1980

TTTAGAGGCA TGACATTTGA AGAAGCTGAA GAAGAACCTT ACATATTGGC AGTAGGGGCG 2040

GAAGGGCTCT GGAAGCAGCG TCTGGATAGC TACGGGCCAG GGGAATTCCT TTATCCTCAT 2100

ATTAGAAATA TTTCAGACCT CGACTGGTAT AATGACACTC TGTATTGGAG TAATTCCATG 2160

GGGAAAGTTC AGACCTGGTC AATGAATAAG AAAGAGGGTA CCACTGAGAA CAGTTATGTA 2220

CCTGACATCA AAAATGCAAG AATGTTGGCC TTTGACTGGC TGGGACAATG CTTGTATTGG 2280

GCTGGCAAAG CAAATACGAT CTACAGAAAA TCACTGCTAG GAGACCATAT GGATGTTGTG 2340

GCCCATGTTG TATATGTAGT GAAGGATCTA GCGGTGGATT CAGTGAATGG CTATTTGTAT 2400

TGGGCCACAA CGTATACAGT GGAGAGTGCA AGACTGAATG GAGAAGAGTA CCTTATATTA 2460

CAGGAGCATC TACAGTTTTC TGGAAAACAG GTGGTTGGTT TAGCTTTGGA TCTCACCTCT 2520

GGTTTTCTTT ACTGGCTTGT GCAAGATGGT CTATGCCTAA ACCTATACAG AATTTCTATT 2580

TGCAAAGAAA GTTGTGGTAA TATCATGGTC ACAGAAATCT CAGCATGGAG TGTTTCGGAA 2640

GTATCTCAGA ATGCACTGCA GTATTACAGT GGTCGTCTGT TCTGGATTAA TAGGCTTAAA 2700

TTCATTACAA CTCAGGAACT CAACCAGAGC ATTAGCATTC CCTTTTCAGA ACCAGCTGAG 2760

TTTGCAGCCT TTACCCTTGT TCACACATCA CTTAAACCTT TGCCAGGAAA TTTCTCTTTT 2820

ACACCAAAAG TGATTCCAAG TTCGGTGCCA GAATCTTCTT TCAAGATTAA AGGAAATTCT 2880

TCAAGTTTTC ACATCATTTG GAATGCCTCC ACAGATGTGC AATGGGGAAC TGTCTTTTAC 2940

TGCGTGGGAT CAAATGCTCT ACAAACTTTG GAGAGTGAAC GGTGCCTCCA TCCGCATGAC 3000

CTCACAGTTC CATCCTACAA AGTTGATTGG CTGGAACCAT TCACACTCTT TGATTTTAGT 3060

GTCACTCCGT ACACATACTG GGGCAAGGCA CCAACAACAT CTGTGTATCT TCGAGCCCCT 3120

GAAGCAGTTC CTTCAGCCCC TGCAAACCCT AGAATATATG TGTTGCATAG TAACACACAT 3180

GAAGGTGAAG AGAAAGTCCT TGTGGAGCTC AGATGGGACA AACCTGAAAG GGACAATGGA 3240

GTATTAACAC AATTCAGGGT TTACTATCAA CTGTTGTATG AGAGTGGTGC TGCTGACACT 3300

CTCATGGAGT GGAATGTGAG CGATGTCAAA CCCACTGCAT TGCTCTTTTC AATCAGAGAT 3360

GTGCATCCTA GGCTCACAGT AAGGTTTCAG GTGCAAGCTT TTACATCTGT GGGTCCAGGA 3420

CCTATGTCTG ATGTAGCACA GAGGAATTCA TCAGATATTT TCCCTGTCCC AACTCTTATA 3480

ACTTTTTCTT CCAACAAGTT GTTTCTTACT GACATAGACA GTAATCATAC CATATGGGAA 3540

GTTTTGACAA ATAGAAATAT AAAGGACATC TGTTATACTG CTGATGATGA CAAAGTGTAT 3600

TATATCCTAG AAGACTCTCT TTTTCTTCTG AATGTACAGA GTACTTCAGA GTCTCAGTTG 3660

TTCGAAGATG TATTTCTTCG CAATGTCACA GCCATCACAG TAGATTGGAT TGCAAGACAT 3720

CTCTTTGTTG CCATGAAAAC GTCATGGAAT GAAACTCAAG TATTTTTTAT TGATCTGGAG 3780

CTCAAGACAA AGTCCTTAAA AGCATTGAAC ATACAGTTGG GTAAACGTAA TTCAACTATA 3840

TCATCTCTAC TGTCATATCC CTTTTTAAGC CGCTTGTATT GGATTGAAGA GCTTGATTAT 3900

GGCAGCCGCA TGTTTTATTA TGATATACTG AATAATACCA TGTACCACAT TTTGGGATAC 3960

GAATCAGTAG AAGAAAAGAT GAGGAACTAC TGCAACTGTA ACGTGGCAGA AGCAGAGCTA 4020

GGAAGACCTA TAAGTATAGA TGTAACTGAC ATCAAGAAAC CCCAACTGCT CTTTATCAGA 4080

GGAAGAGATG AAATATGGGC CTCAGATGTG GATGGTTGCC ACTGCTGGAG GATTACCAAG 4140

ATACCAAGTT TTCAAGGTAC AAAAATTGGA AGCTTGACTG TAGATAAACA ATTTATATAT 4200

TGGACCATTG AAAAGAAGGA ATACACAGAA ATTTGTCTAG CAGATAAAGA AAGCACAAGA 4260

CACTCTCTTC AGAGGAAAGC AAATCATGAG CTGAAAATCT TAGCCTACAG CTCAGCAATG 4320

CAATCATATC CAGATAAGAA GTGCCTGACT CCATTACTAG ACACTGAGAA ACCTACTATC 4380

CTCGATACAA CAAACACTAG TTTTACGTTA AGCTTACCAT CTGTCACAAC ACAGCAGCTA 4440

TGCCCCAGCA TATCCCAGCC TACACCAACA TATCTGGTAT TTTTCAGAGA AATAACTAGC 4500

AACCATGAGA ACTCGACCTA CCATTTCTCT ACTCTACTGC AAAAAACTTT GGAAATTCAG 4560

GAACCTATTG CTGTCATAAA CAACCTAAAA CCATTTTCAA GCTACGCCAT ACAAGTTGCT 4620

GTGAAAAACT ACTATTCAAA TCAAAACCAG CTGGCTGTAG GAAGGGAGAC AATCAGCACA 4680

ACTCTATATG GAGTACCAGA GGGAGTTGAT TCCATTAAGA CAGTGGTTTT GTCCGACACT 4740

ACTATCAACA TATCTTGGAG TGAACCTCTG GAGCCAAATG GACCTCTAGA ATCCATCCGC 4800

TATCAAATCT CTGTCAATTT ATTGTCTTTG TTCCCAGAAG CTCCCTTGCG AAAAAGTGAA 4860

TTTCCAAATG GGACGCTTTC ATGGTCTGTC AGTGATCTCC AGTCTGGAAC AAACAATTTG 4920

TTCAAGGTTC TTGCTTTTCA TCCCAATGAG AACTGGTTTT CTGAAAGTGT CCCTGTTATT 4980

GCAAAAACTT TTGAGACTCC ACTTTCACCT TCCAATATAA TCCCCAGAAA TACTAGTTTC 5040

CAGCTAGAAT GGAGAGCTCC TCTGCACATC AATGGAACCA GCTTCTGGTT TGAGCTGCGT 5100

AAGTGGCAAA CAAGAAGTGA CTGGTTTTCT CCTGCAAGCA CTACATGCAC TGTGGGCCCT 5160

GTTTACACAT GCAATCTCAC TGGAACTCTT CCTTCTGCCA ATTATCTTGT AAGAGCAACA 5220

GTAGTATATG TTACAGGAAT GAAAAGCACT TCCTCTCCAA CAAGCTTTAA AACTACAGCC 5280

AAAGCTGGTG TTCCCAGTAA GCCAGGAACA CCCAAAAGAG CAGAAGACTC TAAAAACTCT 5340

GTACAGTGGG AAAAGGCTGA AGACAATGGA AGCAACCTCA CCTACTACAT CTTAGAAAGC 5400

AGAAAGCAGT CTGGCAACAC CAACAAAGTG AAGTCCTTAT GGGTGGTGGT TTACAATGGT 5460

TCTTGTGACA GCATTTGCAC ATGGAAGGCC GAGAACTTAG AAGGAACTTT TCAGTTCAGA 5520

GCAGCAGCTG CAAATATGCT GGGGCTTGGT GAATACAGTG ACACAAGCAA AGATATTGTG 5580

TTGGCTAAAG ATACTGTGAC CTCTCCAGAT ATCACTGCTA TTGTTGCTGT GATTGGAGCA 5640

GTTGTACTGG GCTTGACTAT AATCATACTG TTTGGTTTTG TATGGCACCA AAGATGGAAA 5700

TCCAGAAAAC CAGCCTCAAC TGGGCAGATT GTGCTTGTCA AGGAAGATAA AGAATTAGCT 5760

CAACTTAGGG GAATGGCTGA GACAGTGGGA TTAGCCAATG CTTGTTATGC TGTCAGCACT 5820

CTTCCTTCTC AAGCAGAGAT TGAGTCATTG CCAGCTTTTC CTCGGGACAA ACTGAACTTA 5880

CACAAGTTGT TAGGAAGTGG AGCATTTGGA GAGGTGTATG AAGGGACTGC ATTAGATATC 5940

CTGGCAGATG GAAGTGGAGA ATCCAGAGTA GCAGTCAAGA CTTTGAAGAG AGGTGCAACA 6000

GACCAAGAGA AGAGTGAATT CTTGAAGGAG GCACACTTAA TGAGTAAATT TGATCATCCC 6060

CACATTCTGA AGCTACTTGG AGTGTGTCTG TTAAATGAAC CTCAGTACCT TATACTGGAG 6120

CTGATGGAAG GAGGAGATCT GCTTAGCTAT TTACGAGGAG CCAGAAAGCA AAAGTTCCAG 6180

AGTCCCTTAC TGACATTGAC TGATCTCTTG GATATATGCT TGGATATTTG CAAAGGTTGT 6240

GTCTATTTAG AGAAAATGCG TTTCATACAC AGGGACCTGG CTGCTCGCAA CTGCCTTGTG 6300

TCTGAGAAGC AATATGGGAG CTGCTCCCGA GTGGTAAAGA TTGGTGATTT TGGACTTGCC 6360

AGAGATATCT ATAAAAATGA TTACTACAGG AAAAGAGGAG AAGGCCTACT CCCTGTCAGA 6420

TGGATGGCTC CTGAAAGCCT CATTGATGGC GTCTTTACAA ATCACTCTGA TGTTTGGGCT 6480

TTTGGAGTCT TAGTGTGGGA AACATTAACT TTGGGTCAAC AGCCATATCC GGGTCTCTCC 6540

AATATAGAAG TTTTACACCA TGTACGATCA GGAGGAAGGC TGGAATCTCC GAATAACTGT 6600

CCTGATGACA TACGTGATTT AATGACACGA TGCTGGGCCC AAGATCCTCA CAACAGACCT 6660

ACTTTCTTTT ATATTCAGCA CAAACTGCAA GAGATAAGGC ACTCTCCACT GTGCTTCAGC 6720

TACTTCCTTG GAGACAAAGA GTCAGTGGCT GGGTTCATCA ACCAAGCTTT TGAGGGTAAG 6780

CCTGGG 6786

Domain Profile

S: 1     lklrlllgsgafgevyegtavdilkvesgeikvavktlkkgstdqekiellkeaqlmskf  60

         l+l++llgsgafgevyegta+dil  +sge +vavktlk+g+tdqek e+lkea+lmskf

Q: 1958  LNLHKLLGSGAFGEVYEGTALDILADGSGESRVAVKTLKRGATDQEKSEFLKEAHLMSKF  2017

         6899********************************************************

S: 61    khenilkllgvclltesqylilelmeagdllsylrkarattfqepsltlvdlvelcvdis  120

         +h+ ilkllgvcll+e+qylilelme+gdllsylr ar   fq p ltl+dl+++c+di+

Q: 2018  DHPHILKLLGVCLLNEPQYLILELMEGGDLLSYLRGARKQKFQSPLLTLTDLLDICLDIC  2077

         ************************************************************

S: 121   kgcvyledmhfihrdlaarnclvsvkdyts.rrvvkigdfglardiykndyyrkrgegll  179

         kgcvyle+m fihrdlaarnclvs k+y s  rvvkigdfglardiykndyyrkrgegll

Q: 2078  KGCVYLEKMRFIHRDLAARNCLVSEKQYGScSRVVKIGDFGLARDIYKNDYYRKRGEGLL  2137

         ****************************8647****************************

S: 180   pvrwmapeslvdglfttqsdvwsfgilvweiltlgqqpyaarsnldvlayvkeggrleqp  239

         pvrwmapesl+dg+ft  sdvw+fg+lvwe ltlgqqpy+  sn++vl +v++ggrle p

Q: 2138  PVRWMAPESLIDGVFTNHSDVWAFGVLVWETLTLGQQPYPGLSNIEVLHHVRSGGRLESP  2197

         ************************************************************

S: 240   rnctddlynllllcwaqepderptfrriqnql  271

         +nc+dd+ +l+++cwaq+p++rptf  iq++l

Q: 2198  NNCPDDIRDLMTRCWAQDPHNRPTFFYIQHKL  2229

         **************************999876

Domain Sequence
(FASTA)

LNLHKLLGSG AFGEVYEGTA LDILADGSGE SRVAVKTLKR GATDQEKSEF LKEAHLMSKF 60

DHPHILKLLG VCLLNEPQYL ILELMEGGDL LSYLRGARKQ KFQSPLLTLT DLLDICLDIC 120

KGCVYLEKMR FIHRDLAARN CLVSEKQYGS CSRVVKIGDF GLARDIYKND YYRKRGEGLL 180

PVRWMAPESL IDGVFTNHSD VWAFGVLVWE TLTLGQQPYP GLSNIEVLHH VRSGGRLESP 240

NNCPDDIRDL MTRCWAQDPH NRPTFFYIQH KL 272

Keyword

ATP-binding; Complete proteome; Kinase; Membrane; Nucleotide-binding; Phosphoprotein; Receptor; Reference proteome; Transferase; Transmembrane; Transmembrane helix; Tyrosine-protein kinase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>

Gene Ontology

GO:0016021	; C:integral to membrane
GO:0005524	; F:ATP binding
GO:0004714	; F:transmembrane receptor protein tyrosine kinase activity
GO:0030154	; P:cell differentiation
GO:0016049	; P:cell growth
GO:0008283	; P:cell proliferation
GO:0010629	; P:negative regulation of gene expression
GO:0070372	; P:regulation of ERK1 and ERK2 cascade
GO:0010966	; P:regulation of phosphate transport
GO:0032006	; P:regulation of TOR signaling cascade
GO:0007169	; P:transmembrane receptor protein tyrosine kinase signaling pathway

KEGG

gga:396192

;

InterPros

IPR011042	; 6-blade_b-propeller_TolB-like.
IPR003961	; Fibronectin_type3.
IPR013783	; Ig-like_fold.
IPR011009	; Kinase-like_dom.
IPR000033	; LDLR_classB_rpt.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR001245	; Ser-Thr/Tyr_kinase_cat_dom.
IPR008266	; Tyr_kinase_AS.
IPR020635	; Tyr_kinase_cat_dom.
IPR002011	; Tyr_kinase_rcpt_2_CS.

Pfam

PF00041	; fn3; 3.
PF07714	; Pkinase_Tyr; 1.

SMARTs

SM00060	; FN3; 9.
SM00135	; LY; 3.
SM00219	; TyrKc; 1.

Prosites

PS50853	; FN3; 9.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00109	; PROTEIN_KINASE_TYR; 1.
PS00239	; RECEPTOR_TYR_KIN_II; 1.

Prints

PR00109

; TYRKINASE.

Created Date

20-Feb-2013