EKS-GAG-00400

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-GAG-00400

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/CAMK1	361.8	2.2E-108	47	301	255

Status

Unreviewed

Ensembl Protein

ENSGALP00000024483

UniProt Accession

E1C503;

Protein Name

Protein Synonyms/Alias

Gene Name

CAMK4

Gene Synonyms/Alias

CAMK4;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSGALG00000015203	ENSGALP00000024483	ENSGALT00000024529

Organism

Gallus gallus

Functional Description

Protein Length

388

Protein Sequence
(FASTA)

MLGSVLPGSC WETPLPPPSA GTMPSSKTDG EYWIDGSHRE AALEDFYVVG PELGRGATSV 60

VYSCEEKGTR TPYAAKILKK TIDKKIVRTE IGVLLRLSHP NIIKLKEIFE TPSEIALVLE 120

LVTGGELFDR IVERGFYSER DAAHVVKQIL EAVSYLHENG VVHRDLKPEN LLYADLSPDA 180

PLKIGDFGLS KIVDEQDTMK TVCGTPGYCA PEILHGCPYG PEVDMWSVGV ITYILLCGFE 240

PFFDPRGDQY MYSRILTCDY EFVSPWWDEV SLNAKDLVRK LIVLDPQKRL TVYQALEHPW 300

VTGKAAKFAH MDSTQKKLQE FNARRKLKAA MKAVVASSRL GNHGHHDCSR SRGGPRGRES 360

TEATSASEEL EAFPAVPTVP VNGASCRS 388

Nucleotide Sequence
(FASTA)

ATGCTGGGCT CTGTTCTGCC CGGCAGCTGC TGGGAGACCC CCCTCCCCCC CCCCTCCGCA 60

GGCACCATGC CTTCCTCCAA GACGGATGGT GAGTATTGGA TCGATGGATC CCACCGTGAG 120

GCCGCCCTGG AGGACTTCTA CGTCGTGGGC CCCGAATTGG GACGGGGAGC CACCTCTGTG 180

GTGTACAGCT GCGAGGAGAA GGGCACACGT ACCCCATATG CTGCCAAGAT CCTGAAGAAG 240

ACAATTGACA AAAAGATCGT GAGGACGGAG ATCGGGGTCC TGCTGCGCCT CTCACACCCC 300

AACATTATCA AACTGAAGGA GATCTTCGAG ACGCCCTCGG AGATCGCGCT GGTGCTGGAA 360

TTGGTGACGG GAGGAGAGCT CTTTGACAGG ATCGTGGAGA GGGGGTTCTA CAGTGAGCGG 420

GATGCAGCCC ACGTGGTCAA GCAGATCCTG GAGGCGGTGT CGTATCTGCA TGAGAATGGA 480

GTGGTGCACC GGGACCTGAA GCCGGAGAAC CTGCTGTATG CAGACCTGTC CCCCGATGCG 540

CCCCTAAAGA TCGGTGACTT CGGGCTCTCT AAGATCGTGG ATGAGCAGGA CACCATGAAA 600

ACTGTCTGTG GGACGCCGGG GTACTGCGCC CCTGAAATCC TGCACGGCTG CCCCTATGGC 660

CCTGAGGTGG ACATGTGGTC GGTGGGCGTC ATCACCTACA TCCTGCTCTG CGGCTTCGAG 720

CCCTTCTTTG ACCCACGTGG GGACCAATAC ATGTACAGCC GCATCCTCAC CTGTGACTAC 780

GAGTTCGTGT CCCCATGGTG GGATGAGGTT TCCCTTAACG CCAAGGACCT GGTCAGGAAG 840

CTGATCGTCT TGGATCCCCA GAAGAGGCTG ACGGTCTATC AGGCTCTGGA GCATCCCTGG 900

GTCACCGGGA AAGCCGCCAA GTTTGCCCAC ATGGACAGCA CGCAAAAGAA GCTGCAGGAA 960

TTTAACGCCA GGAGGAAACT GAAGGCTGCC ATGAAAGCCG TGGTGGCTTC CAGCCGCTTG 1020

GGCAACCACG GCCATCACGA CTGCTCCAGG AGCCGGGGGG GTCCCCGGGG GAGGGAGAGC 1080

ACCGAGGCCA CCTCTGCATC CGAGGAGTTG GAGGCGTTCC CTGCTGTGCC CACCGTGCCC 1140

GTCAATGGGG CGAGCTGCAG GAGCTGA 1167

Domain Profile

S: 1     yklkeklGeGafsevlkakekktqkavaikvikkkalkgkeesveneiavlkklkhpniv  60

         y +  +lG+Ga+s v+ ++ek t+ ++a k++kk+    +++ v++ei vl +l+hpni+

Q: 47    YVVGPELGRGATSVVYSCEEKGTRTPYAAKILKKTI---DKKIVRTEIGVLLRLSHPNII  103

         667789**************************9988...89*******************

S: 61    alkdiyesksklylvlelvtGGelfdrivekgvytekdasevikqvleavkylhelgivh  120

         +lk+i+e++s++ lvlelvtGGelfdrive+g+y+e+da++v+kq+leav+ylhe+g+vh

Q: 104   KLKEIFETPSEIALVLELVTGGELFDRIVERGFYSERDAAHVVKQILEAVSYLHENGVVH  163

         ************************************************************

S: 121   rdlkPenllylskeedskikiadfGlskleeke.llktacGtvgyvapevlkqkkyskkv  179

         rdlkPenlly++ + d+++ki dfGlsk+ +++  +kt+cGt+gy+ape+l+ ++y+ +v

Q: 164   RDLKPENLLYADLSPDAPLKIGDFGLSKIVDEQdTMKTVCGTPGYCAPEILHGCPYGPEV  223

         ****************************888777**************************

S: 180   dvWsiGvityillcGyppfydekeekl.lekilkgeyefesPyWdeisesakdfikklle  238

         d+Ws+GvityillcG++pf+d + +++  ++il+++yef sP+Wde+s +akd+++kl+

Q: 224   DMWSVGVITYILLCGFEPFFDPRGDQYmYSRILTCDYEFVSPWWDEVSLNAKDLVRKLIV  283

         *********************998886379******************************

S: 239   ldpekrytieqaledpWi  256

         ldp+kr+t+ qale+pW+

Q: 284   LDPQKRLTVYQALEHPWV  301

         *****************7

Domain Sequence
(FASTA)

YVVGPELGRG ATSVVYSCEE KGTRTPYAAK ILKKTIDKKI VRTEIGVLLR LSHPNIIKLK 60

EIFETPSEIA LVLELVTGGE LFDRIVERGF YSERDAAHVV KQILEAVSYL HENGVVHRDL 120

KPENLLYADL SPDAPLKIGD FGLSKIVDEQ DTMKTVCGTP GYCAPEILHG CPYGPEVDMW 180

SVGVITYILL CGFEPFFDPR GDQYMYSRIL TCDYEFVSPW WDEVSLNAKD LVRKLIVLDP 240

QKRLTVYQAL EHPWV 255

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR020636	; Ca/CaM-dep_Ca-dep_prot_Kinase.
IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013