EKS-GAG-00099

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-GAG-00099

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/NAK	341.7	3.2E-102	1	265	265

Status

Unreviewed

Ensembl Protein

ENSGALP00000037024

UniProt Accession

F1NC57;

Protein Name

Protein Synonyms/Alias

Gene Name

GAK

Gene Synonyms/Alias

GAK;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSGALG00000015352	ENSGALP00000037028	ENSGALT00000037822
ENSGALG00000015352	ENSGALP00000024729	ENSGALT00000024775
ENSGALG00000015352	ENSGALP00000037024	ENSGALT00000037818

Organism

Gallus gallus

Functional Description

Protein Length

1225

Protein Sequence
(FASTA)

GGFAFVYEAQ DLGSGKDYAL KRLLSNEEEK NKAIIQEVCF MKKLSGHPNI VQFCSAASIG 60

KEESDTGQGE FLLLTELCKG QLVEFLKKVE PKGPISCDTV LKIFYQTCRA VQHMHKQKPP 120

IIHRDLKVEN LLISNQGTIK LCDFGSATTV AYYPDYSWSA QKRALVEEEI TRNTTPMYRT 180

PEMIDLYSNF PISEKQDIWA LGCILYLLCF RQHPFEDGAK LRIVNGKYAI PQNDTRYSVF 240

HDLIRSTLKV NPEERLSITE LVNQLQEIAA ARNVNPKSPI TELLEQNGGY GNNAQPRSTT 300

LGLTVAECDQ TYGGFFDILR GGTERFFTNI KDTSSKVIQS VANYAKGDLD ISYITSRIAV 360

MSFPAEGVES AIKNNIEDVR LCLDSKHPGH YAVYNLSPRT YRPSRFHNRV SECGWPARRA 420

PNLQNLYSIC KNMHLWLKQD QKNVCIVHCL DGRAASAVVV CSFLCFCRLF TTAEAAVYMF 480

SMKRCPPGIW PSHKRYIEYM CDMMAEEPII PHSKPILVRS IIMTPVPLFS KQRNGCRPFC 540

EVYVGDERIT TTSQEYDKMK EFKIEDGKAV IPLGITVQGD VLIVIYHARS TLGGRLQAKM 600

ASMKMFQIQF HTGFVPRNAT TVKFAKYDLD ACDIQEKYPD LFQVNLEVEV EPRDRPSCEQ 660

LPWDNMNIKG LNPKILFSTR EEQQEILSKF GKPELPRQPG STAQYEAEAS QLDLSSESAP 720

TEGESPHSSG TDANNFFHSL DWKEGRSPES GVDDTSSKND HGQLSDEREE SDPSDEEFPT 780

FPGEERAVSV DEGDSATPEE ENVDLLGLNS DASPEQKEPI SEINSSSNAA LLNNLFVSGA 840

SQVSEEPTGD LLGQGADFFF SGQSQHPAVT QTSAAAASSA DPFDPFTMSS SSENSALSGP 900

DLFGDFLNPS AASTANTFSS THSSLPPSSS SDFLNLAGNL TSEPPKMSSS TSHPDLLGGW 960

DSWADSSAAS NVASRQVFTT GSQSSVSSGS SFSQAKSQNF DPFADLANLG SSLPGSSTGG 1020

FSTSGFAQKT VPSQKSGGQW QKPTKPQTWQ SQAKSGTQAK PNYTVNFSVI GGREERGVRT 1080

PSFGQKPKVS ANDFEDLLSN QGFSAKSDKK GPKTIAEMRK QEMSKDMDPL KLKILEWIEG 1140

KERNIRALIS TLHTVLWEGE NKWKPVSMAD LVTPEQVKKY YRKAVLVVHP DKATGQPYEQ 1200

YAKMIFMELS DAWSEFENQG SKSLF 1225

Nucleotide Sequence
(FASTA)

GGTGGTTTTG CATTTGTCTA TGAAGCTCAG GATCTTGGAA GTGGCAAAGA CTATGCTTTA 60

AAGCGGTTGT TGTCCAATGA GGAAGAGAAG AACAAAGCTA TCATTCAGGA AGTTTGCTTT 120

ATGAAAAAAC TTTCAGGTCA CCCCAACATA GTCCAGTTCT GCTCTGCTGC ATCTATAGGG 180

AAAGAAGAAT CAGACACAGG ACAAGGAGAG TTCCTTCTGC TTACAGAATT GTGTAAAGGA 240

CAACTGGTGG AATTCTTAAA GAAAGTGGAA CCCAAAGGGC CAATCTCCTG TGACACAGTC 300

CTGAAGATCT TTTATCAGAC CTGCCGAGCA GTCCAGCATA TGCATAAACA GAAGCCACCT 360

ATTATCCATA GAGATTTAAA GGTGGAGAAC TTGCTTATTA GTAACCAAGG GACAATTAAA 420

CTTTGCGACT TCGGTAGTGC TACAACAGTA GCTTACTATC CTGACTACAG CTGGTCTGCA 480

CAAAAGAGAG CACTAGTTGA AGAAGAGATC ACCAGGAATA CAACGCCAAT GTACAGGACA 540

CCAGAGATGA TAGATTTATA TTCAAATTTT CCAATCAGTG AAAAGCAGGA CATTTGGGCT 600

TTGGGCTGTA TCCTGTACCT CCTGTGCTTT AGGCAACATC CCTTTGAAGA TGGAGCTAAA 660

CTTCGCATAG TCAATGGAAA ATATGCCATT CCACAGAACG ACACCCGCTA CTCTGTATTT 720

CATGATCTCA TCCGCTCCAC TTTGAAGGTG AACCCAGAGG AGAGATTGTC AATCACTGAA 780

CTTGTGAATC AACTGCAGGA GATTGCAGCA GCTAGGAATG TAAATCCTAA ATCCCCCATC 840

ACAGAGCTCT TGGAACAAAA TGGAGGCTAT GGAAACAATG CTCAGCCTCG ATCAACTACT 900

CTAGGCCTGA CCGTTGCGGA ATGTGACCAG ACTTATGGAG GGTTCTTTGA TATTCTGAGG 960

GGTGGAACGG AGCGATTTTT CACTAATATT AAGGATACAT CTTCTAAAGT TATCCAGTCT 1020

GTGGCCAATT ATGCGAAAGG GGACTTGGAT ATATCATACA TCACTTCGAG AATTGCAGTG 1080

ATGTCCTTTC CAGCTGAAGG TGTAGAATCT GCCATCAAAA ACAACATAGA AGATGTACGA 1140

TTATGTCTGG ACTCCAAACA TCCTGGGCAC TATGCTGTGT ATAATCTTTC TCCAAGGACA 1200

TACAGACCTT CACGATTCCA TAATAGGGTT TCTGAATGTG GCTGGCCAGC AAGACGAGCA 1260

CCAAATCTTC AGAATCTCTA TAGCATATGC AAGAACATGC ATTTATGGCT GAAACAGGAC 1320

CAGAAAAATG TTTGCATTGT TCATTGCCTA GATGGAAGAG CAGCATCTGC TGTTGTAGTT 1380

TGTTCTTTTC TGTGTTTCTG TCGTCTCTTC ACTACTGCTG AGGCTGCAGT TTATATGTTC 1440

AGTATGAAAC GCTGTCCTCC TGGCATATGG CCTTCTCATA AAAGATACAT TGAATACATG 1500

TGTGACATGA TGGCTGAAGA GCCCATTATT CCTCACAGCA AGCCAATCCT GGTCAGATCC 1560

ATCATCATGA CTCCAGTTCC TCTTTTCAGT AAGCAGCGTA ATGGCTGCAG GCCTTTTTGT 1620

GAAGTTTATG TAGGGGATGA GAGAATAACC ACTACCTCCC AGGAATACGA CAAAATGAAG 1680

GAGTTTAAAA TTGAAGACGG GAAAGCAGTA ATTCCATTGG GTATAACGGT TCAAGGAGAT 1740

GTTCTCATTG TTATCTATCA TGCTAGGTCA ACACTAGGAG GCCGACTACA AGCCAAGATG 1800

GCTTCTATGA AGATGTTTCA GATCCAGTTC CACACAGGTT TTGTGCCCCG AAATGCCACC 1860

ACAGTGAAAT TTGCAAAGTA TGATCTGGAT GCCTGTGACA TTCAAGAAAA ATATCCTGAT 1920

TTATTTCAAG TCAATCTGGA AGTGGAGGTG GAGCCCAGAG ATAGGCCTAG CTGTGAGCAG 1980

CTGCCATGGG ATAACATGAA TATAAAGGGT CTGAATCCCA AGATCCTTTT CTCCACTCGA 2040

GAGGAACAGC AGGAAATTTT GTCAAAATTT GGGAAACCAG AGCTACCAAG GCAGCCAGGT 2100

TCAACTGCGC AGTATGAAGC AGAAGCATCC CAACTGGATC TGTCCTCAGA AAGTGCCCCA 2160

ACTGAGGGAG AATCCCCCCA CAGCAGTGGT ACTGATGCAA ATAACTTCTT TCATTCTCTG 2220

GATTGGAAAG AAGGAAGAAG TCCAGAAAGT GGAGTAGATG ATACCTCATC TAAAAATGAT 2280

CATGGTCAAC TGTCTGATGA GAGAGAAGAG AGTGATCCTT CAGATGAGGA GTTCCCTACA 2340

TTTCCAGGTG AAGAAAGGGC AGTAAGTGTT GATGAGGGAG ACTCTGCTAC CCCAGAAGAA 2400

GAGAATGTAG ATTTACTGGG ACTGAATTCC GATGCTTCAC CAGAACAGAA AGAACCTATC 2460

TCAGAAATAA ACTCATCAAG TAATGCAGCC CTGCTGAACA ATCTTTTTGT GAGTGGTGCA 2520

TCTCAGGTTT CAGAAGAGCC CACTGGAGAT CTCCTTGGAC AAGGAGCAGA TTTCTTTTTC 2580

AGTGGTCAAT CTCAGCATCC AGCTGTTACT CAGACTTCAG CAGCAGCTGC ATCTTCAGCT 2640

GATCCTTTTG ACCCATTTAC AATGTCATCT AGTTCTGAGA ATTCAGCGCT GTCTGGCCCA 2700

GACCTTTTTG GAGACTTTCT TAATCCAAGC GCAGCATCTA CAGCTAATAC GTTTTCCTCT 2760

ACACATAGTT CACTTCCACC TTCTTCCAGT TCAGATTTCC TAAATTTAGC AGGAAATTTG 2820

ACATCAGAGC CACCTAAAAT GTCGTCTTCT ACTAGCCATC CAGATCTCTT AGGTGGATGG 2880

GATTCTTGGG CAGATTCTTC AGCAGCCAGC AATGTAGCAT CACGTCAAGT TTTTACCACA 2940

GGGAGCCAGT CCAGCGTGTC TTCAGGTTCA TCTTTCAGCC AAGCTAAATC TCAGAACTTT 3000

GATCCTTTTG CTGATCTTGC CAATCTTGGA TCTAGTCTTC CAGGTTCCTC CACAGGTGGA 3060

TTCTCCACTA GTGGGTTTGC TCAGAAAACT GTTCCATCTC AGAAGTCAGG AGGTCAGTGG 3120

CAGAAACCCA CAAAACCACA AACATGGCAG TCCCAAGCTA AATCTGGTAC ACAAGCTAAA 3180

CCTAACTACA CAGTGAACTT CAGTGTTATT GGAGGACGAG AAGAAAGGGG AGTCAGAACC 3240

CCAAGCTTTG GTCAAAAGCC AAAAGTTTCA GCCAATGACT TTGAGGATCT CTTATCTAAT 3300

CAAGGCTTTT CAGCAAAATC TGATAAAAAG GGACCAAAAA CTATTGCTGA GATGAGGAAA 3360

CAAGAAATGT CTAAAGATAT GGACCCCTTG AAACTGAAGA TTCTTGAATG GATTGAAGGA 3420

AAGGAGAGAA ATATCAGAGC ATTAATATCT ACTCTTCATA CAGTGCTTTG GGAAGGGGAA 3480

AATAAATGGA AACCAGTTAG CATGGCAGAT CTAGTAACTC CTGAACAAGT GAAGAAGTAC 3540

TACCGGAAAG CAGTGCTTGT GGTTCATCCA GATAAGGCGA CAGGACAACC TTATGAGCAG 3600

TATGCCAAAA TGATCTTCAT GGAATTGAGT GATGCGTGGT CGGAATTTGA GAACCAGGGG 3660

TCTAAGTCCC TCTTCTAA 3678

Domain Profile

S: 10    GGfalvylaedastgekyalKrilvneeedleeikrEieimkklsghknivklv..dssv  67

         GGfa+vy a+d+ +g+ yalKr+l+neee++++i++E+++mkklsgh+niv+++  +s

Q: 1     GGFAFVYEAQDLGSGKDYALKRLLSNEEEKNKAIIQEVCFMKKLSGHPNIVQFCsaASIG  60

         9*****************************************************777888

S: 68    keekdngskevlllleyckkgslvdllnkrlekgelseaeilkilldvtravaalHalsv  127

         kee+d+g+ e+lll+e+ck g+lv++l+k + kg +s++++lki+++++rav+++H++++

Q: 61    KEESDTGQGEFLLLTELCK-GQLVEFLKKVEPKGPISCDTVLKIFYQTCRAVQHMHKQKP  119

         999****************.8***************************************

S: 128   pliHRDlkveNillsdegelvlcDlGSattaileve...skqelsalqeeieknttlsyr  184

         p+iHRDlkveN+l+s++g+++lcD+GSatt    ++   s+q+++ ++eei++ntt++yr

Q: 120   PIIHRDLKVENLLISNQGTIKLCDFGSATTVAYYPDyswSAQKRALVEEEITRNTTPMYR  179

         ***********************************99999********************

S: 185   sPElidlysnlvideksDiWaLGcllYklcffesPfeesvklailngkysiPensrysek  244

         +PE+idlysn++i+ek+DiWaLGc+lY lcf+++Pfe+++kl+i+ngky iP+n++ ++

Q: 180   TPEMIDLYSNFPISEKQDIWALGCILYLLCFRQHPFEDGAKLRIVNGKYAIPQNDTRYSV  239

         ************************************************************

S: 245   lkslikkmlevdpeeRptiaqvlell  270

         +++li++ l+v+peeR++i++++++l

Q: 240   FHDLIRSTLKVNPEERLSITELVNQL  265

         **********************9986

Domain Sequence
(FASTA)

GGFAFVYEAQ DLGSGKDYAL KRLLSNEEEK NKAIIQEVCF MKKLSGHPNI VQFCSAASIG 60

KEESDTGQGE FLLLTELCKG QLVEFLKKVE PKGPISCDTV LKIFYQTCRA VQHMHKQKPP 120

IIHRDLKVEN LLISNQGTIK LCDFGSATTV AYYPDYSWSA QKRALVEEEI TRNTTPMYRT 180

PEMIDLYSNF PISEKQDIWA LGCILYLLCF RQHPFEDGAK LRIVNGKYAI PQNDTRYSVF 240

HDLIRSTLKV NPEERLSITE LVNQL 265

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005794	; C:Golgi apparatus
GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR008973	; C2_Ca/lipid-bd_dom_CaLB.
IPR001623	; DnaJ_N.
IPR011009	; Kinase-like_dom.
IPR014019	; Phosphatase_tensin-typ.
IPR000719	; Prot_kinase_cat_dom.
IPR008271	; Ser/Thr_kinase_AS.
IPR014020	; Tensin_phosphatase_C2-dom.

Pfam

PF00226	; DnaJ; 1.
PF00069	; Pkinase; 1.
PF10409	; PTEN_C2; 1.

SMARTs

SM00271

; DnaJ; 1.

Prosites

PS51182	; C2_TENSIN; 1.
PS50076	; DNAJ_2; 1.
PS51181	; PPASE_TENSIN; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013