EPS-GAG-00013

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-GAG-00013

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
DSP/aDSP	151.5	1.5E-44	135	279	145

Status

Unreviewed

Ensembl Protein

ENSGALP00000024871

UniProt Accession

E1C5I7;

Protein Name

Protein Synonyms/Alias

Gene Name

DUSP27

Gene Synonyms/Alias

DUSP27;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSGALG00000015453	ENSGALP00000024871	ENSGALT00000024917

Organism

Gallus gallus

Functional Description

Protein Length

883

Protein Sequence
(FASTA)

MASGGDSDSE QVVPDEEKDG PDVKAVQAHY LRSPSPSRYS MISDTDTESI FMEPIHLSSA 60

VAAKQIINEE LKTKHIKVDA VCPKMLESAQ QLMVEDLYNR VKEKIDDTSL FNTPCVMDLQ 120

RALVKDRLET PRDAVDEVWP NVFIAEKSVA VNKSRLKRLG ITHVLNAAHG TGVYTGPDFY 180

NGLNIQYMGI EVDDFPDMDI SKHFHPAAEF LDEALLTYRG KILVSSEMGI SRSAVLVAAY 240

LMIYHHMTIL EALMTLRKKR AIYPNDGFLK QLRELNEQLL EEREVEPTGD EGTSSRLSEA 300

EDSESVIGPK AHSITVEEED NSSMLSSFMS SSSVGKASRV SKRSTLISEE EEEQLYEEWR 360

KKQGLPAKES ATDHGKRLLA QEGEQYEEDV EQRIHDWQRR NEKYQREGPP REEDGNSSMG 420

GRPYRSGEFS DDESVSSFEI RTLKRQLEAS SFSRMRRSRT DSVSSESTWD MWNQRLMEIE 480

KEAVQRYRSK NKNGGERQSP DTRGKERDVD EESVLSDCSS FYNFCQKNKD KLTPLERWKI 540

KRIQFGFHKK DLESSSSSAP SPAEDGSQTG EEGTEGKNLS DVNLSAYQAW KMKRQKKVGS 600

ESKEEFVEFA KSEDSASAKK KQRRVELLER SKKILEESQS MCSWETDSTM SGSIPLSAFW 660

ASAPSANGAE DAASTLSMKT NHSSLSQTRS STGATQPNIP LPNLPVGPGD TISMASIQNW 720

IANVVSETIA QKQNEIMMLS RPSSAMASSV MSGDLGRRVD DDKISLLSSQ CGSSFSASHL 780

CQQDMHRAES LSVLSCNTSV SARSEGTSSN MKTMQTSKPL YSLFADDVDL KKLSRKEKEI 840

QMEMREKMSD YQIEKVISDN KRSTLFKKKV TKGEENEIED GVE 883

Nucleotide Sequence
(FASTA)

ATGGCCAGCG GCGGGGATTC AGACAGCGAG CAAGTGGTGC CTGATGAAGA GAAGGATGGC 60

CCAGACGTGA AAGCGGTGCA GGCCCACTAC CTGCGCAGCC CTTCACCCAG CCGGTATTCA 120

ATGATATCGG ACACTGATAC AGAGAGCATA TTCATGGAGC CTATCCATCT GTCATCTGCT 180

GTGGCTGCCA AACAAATAAT CAATGAAGAA CTGAAGACAA AGCACATCAA GGTAGATGCA 240

GTGTGTCCCA AGATGTTAGA GTCTGCACAG CAGTTGATGG TGGAAGATCT ATACAACCGA 300

GTTAAAGAAA AGATTGATGA CACCAGCTTG TTTAACACTC CGTGTGTCAT GGACTTGCAG 360

AGGGCACTTG TAAAGGACAG GCTGGAGACT CCTAGAGATG CTGTGGATGA AGTCTGGCCT 420

AATGTCTTCA TAGCAGAAAA GAGTGTTGCA GTGAACAAAA GCCGTTTGAA GAGACTGGGC 480

ATTACACATG TCTTGAACGC AGCTCATGGT ACAGGTGTAT ACACAGGACC AGATTTCTAC 540

AATGGTCTAA ATATCCAATA CATGGGCATT GAAGTGGATG ATTTTCCAGA TATGGATATC 600

TCCAAACACT TCCATCCAGC TGCAGAGTTC CTGGATGAAG CACTACTGAC TTACAGGGGA 660

AAAATCCTTG TCAGCAGTGA AATGGGAATC AGTCGCTCAG CTGTGCTAGT GGCTGCTTAC 720

CTGATGATCT ATCACCATAT GACCATTCTG GAGGCTCTGA TGACTCTGAG AAAGAAGCGT 780

GCCATTTACC CCAATGATGG CTTCCTCAAG CAGCTAAGGG AGCTTAACGA GCAATTATTG 840

GAGGAACGAG AGGTGGAGCC TACTGGAGAT GAAGGGACAT CTTCCCGGCT ATCTGAAGCT 900

GAGGACTCCG AAAGTGTCAT AGGACCCAAA GCACACTCCA TCACAGTAGA AGAAGAAGAC 960

AACAGCAGCA TGCTAAGTAG TTTTATGAGC TCTTCATCAG TGGGAAAAGC TAGCAGGGTT 1020

TCCAAACGCT CCACCCTCAT CAGTGAGGAG GAAGAAGAAC AGTTATATGA GGAATGGAGG 1080

AAGAAACAAG GCCTGCCTGC AAAGGAATCA GCAACTGACC ATGGAAAAAG GCTTCTGGCT 1140

CAGGAAGGGG AGCAGTATGA GGAGGATGTG GAACAGAGGA TCCATGACTG GCAGCGCAGA 1200

AATGAGAAAT ACCAAAGGGA GGGTCCACCC AGAGAGGAGG ATGGAAATTC TAGCATGGGA 1260

GGAAGACCTT ATCGATCAGG TGAATTTAGT GATGATGAGA GTGTGAGCAG TTTTGAGATC 1320

CGAACCCTAA AGCGACAGTT GGAAGCCAGC AGCTTTAGCA GGATGAGGAG GAGCCGCACA 1380

GACTCTGTAT CTTCAGAGAG CACCTGGGAC ATGTGGAACC AGAGGCTAAT GGAGATTGAG 1440

AAGGAAGCTG TTCAGAGGTA TCGTTCTAAG AATAAGAATG GTGGGGAGAG ACAATCCCCA 1500

GACACGAGAG GAAAGGAGAG GGATGTGGAT GAGGAAAGTG TGTTGTCAGA CTGTAGCTCC 1560

TTCTATAATT TCTGCCAAAA GAACAAAGAC AAATTGACTC CTCTAGAAAG GTGGAAGATC 1620

AAGAGGATCC AGTTTGGCTT TCACAAGAAG GATTTAGAAT CATCATCATC TTCTGCACCA 1680

TCTCCAGCAG AAGATGGCAG CCAGACTGGT GAAGAGGGGA CTGAAGGGAA GAATTTGTCA 1740

GATGTTAATC TGAGTGCTTA CCAGGCTTGG AAGATGAAGC GGCAGAAGAA GGTGGGCTCT 1800

GAAAGCAAGG AGGAATTTGT GGAGTTTGCC AAAAGTGAAG ATTCTGCTTC AGCTAAAAAG 1860

AAGCAGAGGC GTGTAGAGCT CCTTGAACGT TCAAAGAAAA TTTTAGAAGA AAGCCAGTCC 1920

ATGTGCAGCT GGGAGACAGA TAGTACAATG AGTGGGAGTA TCCCGCTGTC TGCTTTCTGG 1980

GCCTCAGCGC CTTCTGCAAA TGGTGCTGAG GATGCAGCTT CTACACTGAG CATGAAGACA 2040

AATCATTCAT CTTTATCACA GACCAGGAGC AGCACTGGGG CAACGCAGCC AAATATTCCC 2100

CTTCCCAATC TCCCAGTTGG CCCAGGTGAC ACGATATCTA TGGCAAGCAT TCAGAACTGG 2160

ATTGCTAACG TGGTCAGTGA AACCATTGCT CAAAAGCAAA ATGAGATCAT GATGCTGTCA 2220

CGTCCATCGT CTGCAATGGC CTCCAGCGTA ATGTCAGGAG ACCTTGGCAG GCGTGTAGAT 2280

GACGATAAGA TTTCCCTTCT CAGTTCTCAG TGTGGCTCAT CCTTTTCTGC CTCTCATCTC 2340

TGTCAGCAGG ACATGCACAG GGCTGAGTCT CTGTCTGTCC TGTCTTGCAA TACCTCTGTG 2400

AGTGCGAGGT CAGAAGGGAC TAGTTCAAAC ATGAAGACTA TGCAAACAAG CAAACCACTG 2460

TATAGCCTCT TTGCCGATGA TGTTGATCTA AAGAAACTCA GCAGGAAGGA GAAGGAGATA 2520

CAAATGGAAA TGAGAGAGAA AATGTCAGAT TACCAAATTG AAAAGGTGAT AAGCGACAAT 2580

AAACGCAGCA CTCTATTTAA GAAAAAGGTG ACCAAAGGAG AGGAAAATGA AATAGAAGAT 2640

GGTGTGGAG 2649

Domain Profile

S: 2     vteilpglylgdqataldrreLsklgitvvinaslsvikvqviPeylikkgityknipvd  61

         v+e++p+++++++ +a+++  L++lgit+v+na++++    ++P+++   +i+y++i+vd

Q: 135   VDEVWPNVFIAEKSVAVNKSRLKRLGITHVLNAAHGTGV-YTGPDFYNGLNIQYMGIEVD  193

         89*********************************8765.79******************

S: 62    Dsdvtdllqyfdeaaefidea.kekggkvlvHCaaGvsRSatlvlaYLmkveglslsdAi  120

         D +++d++++f++aaef+dea  + +gk+lv +++G+sRSa+lv aYLm+++++++ +A+

Q: 194   DFPDMDISKHFHPAAEFLDEAlLTYRGKILVSSEMGISRSAVLVAAYLMIYHHMTILEAL  253

         *********************8999***********************************

S: 121   eavkrkrpsiepnegfleQLlelekkl  147

         +++++kr +i+pn+gfl+QL+el+++l

Q: 254   MTLRKKR-AIYPNDGFLKQLRELNEQL  279

         *******.***************9987

Domain Sequence
(FASTA)

VDEVWPNVFI AEKSVAVNKS RLKRLGITHV LNAAHGTGVY TGPDFYNGLN IQYMGIEVDD 60

FPDMDISKHF HPAAEFLDEA LLTYRGKILV SSEMGISRSA VLVAAYLMIY HHMTILEALM 120

TLRKKRAIYP NDGFLKQLRE LNEQL 145

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0008138	; F:protein tyrosine/serine/threonine phosphatase activity
GO:0006470	; P:protein dephosphorylation

KEGG

InterPros

IPR020417	; Atypical_DUSP.
IPR020405	; Atypical_DUSP_famA.
IPR000340	; Dual-sp_phosphatase_cat-dom.
IPR020422	; Dual-sp_phosphatase_subgr_cat.
IPR024950	; DUSP.
IPR000387	; Tyr/Dual-specificity_Pase.

Pfam

PF00782

; DSPc; 1.

SMARTs

SM00195

; DSPc; 1.

Prosites

PS50056	; TYR_PHOSPHATASE_2; 1.
PS50054	; TYR_PHOSPHATASE_DUAL; 1.

Prints

PR01908	; ADSPHPHTASE.
PR01909	; ADSPHPHTASEA.

Created Date

20-Feb-2013