EKS-GAG-00362

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-GAG-00362

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
AGC/SGK	527.6	7.0E-159	158	415	258

Status

Unreviewed

Ensembl Protein

ENSGALP00000024984

UniProt Accession

F1NEJ3;

Protein Name

Protein Synonyms/Alias

Gene Name

SGK3

Gene Synonyms/Alias

SGK3;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSGALG00000015525	ENSGALP00000024984	ENSGALT00000025030
ENSGALG00000015525	ENSGALP00000030252	ENSGALT00000030889

Organism

Gallus gallus

Functional Description

Protein Length

492

Protein Sequence
(FASTA)

MDLKESCPSV SIPSSDEHRE KKKRFTVYKV LVSVGRNEWF VFRRYAEFDK LYNTLKKQFP 60

TMNLKIPAKR IFGDNFDPGN YFIKQRRAGL NEFIQNLVRQ PELCNHPDVR AFLQMDNPKH 120

QSDPSEDEDE RSNQKLNSTS PNINLGPSGN PHAKPTDFDF LKVIGKGSFG KVLLAKRKLD 180

GKYYAVKVLQ KKIVLNRKEQ KHIMAERNVL LKNVKHPFLV GLHYSFQTTE KLYFVLDFVN 240

GGELFFHLQR ERSFPEHRAR FYAAEIASAL GYLHSINIVY RDLKPENILL DSLGHVVLTD 300

FGLCKEGIAS SDTTATFCGT PEYLAPEVIK KQPYDNTVDW WCLGAVLYEM LYGLPPFYCR 360

DVAEMYENIL HKPLVLRPGI SLTAWSILEE LLEKDRQSRL GAKEDFLEIQ KHPFFESLSW 420

TDLLQKKIPP PFNPNVVGPD DIGNFDAVFT EEMVPYSVCI SSDYSIVNAS VLEADDAFVG 480

FSYAPPSEDM FS 492

Nucleotide Sequence
(FASTA)

ATGGATCTCA AAGAAAGCTG CCCAAGTGTT AGCATTCCCA GCTCGGATGA ACACAGGGAG 60

AAGAAAAAAA GGTTTACTGT TTACAAAGTG TTGGTCTCGG TTGGCAGAAA TGAGTGGTTT 120

GTCTTCAGAC GGTATGCAGA GTTTGATAAG CTCTACAATA CGCTAAAGAA GCAATTTCCC 180

ACTATGAACC TGAAGATTCC AGCTAAAAGA ATATTTGGAG ATAATTTTGA TCCCGGCAAT 240

TATTTTATTA AACAGAGAAG AGCAGGACTG AACGAATTCA TCCAAAACTT AGTTAGACAG 300

CCAGAGCTAT GCAACCACCC AGACGTCAGA GCATTTCTTC AGATGGATAA CCCAAAACAC 360

CAGTCGGATC CATCTGAAGA TGAAGATGAA AGGAGTAATC AGAAGTTAAA TTCTACCTCA 420

CCGAATATCA ACTTGGGACC ATCTGGAAAT CCTCATGCTA AGCCAACGGA CTTTGATTTC 480

CTGAAAGTTA TTGGGAAAGG CAGCTTTGGC AAGGTTCTTC TTGCAAAAAG AAAACTGGAT 540

GGGAAATATT ATGCTGTCAA AGTGCTGCAG AAAAAAATTG TTCTTAACAG GAAAGAGCAA 600

AAACATATCA TGGCTGAACG TAATGTGCTT CTGAAAAATG TGAAACATCC ATTTTTAGTC 660

GGATTACATT ACTCATTCCA AACAACAGAA AAGCTTTACT TTGTCCTGGA TTTTGTTAAC 720

GGAGGAGAGC TGTTCTTTCA TTTACAAAGA GAACGTTCCT TTCCTGAGCA CAGAGCCAGA 780

TTTTATGCTG CTGAAATAGC CAGTGCACTG GGATACTTAC ACTCCATAAA TATTGTGTAC 840

AGGGATTTAA AACCAGAAAA CATTCTCCTA GATTCACTAG GTCATGTTGT GTTGACAGAC 900

TTTGGACTTT GTAAAGAAGG GATTGCAAGT TCTGATACTA CTGCAACATT CTGTGGGACG 960

CCGGAATATC TTGCACCAGA AGTTATTAAA AAGCAGCCCT ATGACAACAC AGTAGACTGG 1020

TGGTGCCTTG GTGCAGTTCT TTATGAAATG CTTTATGGAC TGCCTCCTTT TTACTGCCGT 1080

GACGTTGCTG AGATGTATGA GAATATTCTT CACAAGCCCC TAGTCTTGCG TCCAGGAATC 1140

AGTCTCACAG CCTGGTCTAT TCTGGAGGAA CTTCTGGAGA AAGATCGGCA AAGCAGACTT 1200

GGAGCAAAGG AAGATTTTCT TGAAATTCAG AAGCACCCAT TCTTTGAATC TCTCAGCTGG 1260

ACTGACCTTC TTCAGAAGAA GATTCCACCA CCATTTAATC CTAACGTGGT TGGCCCAGAT 1320

GATATTGGGA ATTTCGATGC GGTGTTTACA GAAGAAATGG TCCCATACTC AGTTTGCATC 1380

TCTTCTGATT ACAGCATTGT TAATGCCAGT GTTCTGGAGG CAGACGATGC CTTTGTTGGG 1440

TTTTCTTATG CACCGCCTTC TGAAGATATG TTTTCCTAG 1479

Domain Profile

S: 1     fdflkvigkgsfgkvllakrkadekfyavkvlqkkailkkkeekhimaernvllknvkhp  60

         fdflkvigkgsfgkvllakrk d+k+yavkvlqkk++l++ke+khimaernvllknvkhp

Q: 158   FDFLKVIGKGSFGKVLLAKRKLDGKYYAVKVLQKKIVLNRKEQKHIMAERNVLLKNVKHP  217

         9***********************************************************

S: 61    flvglhysfqtaeklyfvldyvnggelffhlqrersfleprarfyaaeiasalgylhsln  120

         flvglhysfqt+eklyfvld+vnggelffhlqrersf+e+rarfyaaeiasalgylhs+n

Q: 218   FLVGLHYSFQTTEKLYFVLDFVNGGELFFHLQRERSFPEHRARFYAAEIASALGYLHSIN  277

         ************************************************************

S: 121   ivyrdlkpenilldskghvvltdfglckeeieaedttstfcgtpeylapevlrkkpydrt  180

         ivyrdlkpenillds ghvvltdfglcke+i+++dtt+tfcgtpeylapev++k+pyd+t

Q: 278   IVYRDLKPENILLDSLGHVVLTDFGLCKEGIASSDTTATFCGTPEYLAPEVIKKQPYDNT  337

         ************************************************************

S: 181   vdwwclgavlyemlyglppfysrdvaemydnilnkplqlkpgisvaalelleellekdrk  240

         vdwwclgavlyemlyglppfy+rdvaemy+nil+kpl l+pgis++a+++leellekdr+

Q: 338   VDWWCLGAVLYEMLYGLPPFYCRDVAEMYENILHKPLVLRPGISLTAWSILEELLEKDRQ  397

         ************************************************************

S: 241   krlgakedfleiknhvff  258

          rlgakedflei++h+ff

Q: 398   SRLGAKEDFLEIQKHPFF  415

         *****************9

Domain Sequence
(FASTA)

FDFLKVIGKG SFGKVLLAKR KLDGKYYAVK VLQKKIVLNR KEQKHIMAER NVLLKNVKHP 60

FLVGLHYSFQ TTEKLYFVLD FVNGGELFFH LQRERSFPEH RARFYAAEIA SALGYLHSIN 120

IVYRDLKPEN ILLDSLGHVV LTDFGLCKEG IASSDTTATF CGTPEYLAPE VIKKQPYDNT 180

VDWWCLGAVL YEMLYGLPPF YCRDVAEMYE NILHKPLVLR PGISLTAWSI LEELLEKDRQ 240

SRLGAKEDFL EIQKHPFF 258

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0016023	; C:cytoplasmic membrane-bounded vesicle
GO:0005524	; F:ATP binding
GO:0035091	; F:phosphatidylinositol binding
GO:0004674	; F:protein serine/threonine kinase activity
GO:0007154	; P:cell communication

KEGG

InterPros

IPR000961	; AGC-kinase_C.
IPR011009	; Kinase-like_dom.
IPR001683	; Phox.
IPR017892	; Pkinase_C.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069	; Pkinase; 1.
PF00433	; Pkinase_C; 1.
PF00787	; PX; 1.

SMARTs

SM00312	; PX; 1.
SM00133	; S_TK_X; 1.
SM00220	; S_TKc; 1.

Prosites

PS51285	; AGC_KINASE_CTER; 1.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.
PS50195	; PX; 1.

Prints

Created Date

20-Feb-2013