EPS-GAG-00033

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-GAG-00033

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPM/PP2C	166.1	1.4E-48	323	471	149

Status

Unreviewed

Ensembl Protein

ENSGALP00000026595

UniProt Accession

E1BVR7;

Protein Name

Protein Synonyms/Alias

Gene Name

PPM1G

Gene Synonyms/Alias

PPM1G;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSGALG00000016513	ENSGALP00000026595	ENSGALT00000026646

Organism

Gallus gallus

Functional Description

Protein Length

503

Protein Sequence
(FASTA)

MGAYLSQPNT VKSSGDGAGL GPRPLHFGFS AMQGWRVSME DAHNCIPELD SETAMFSVYD 60

GHGGEEVALY CAKYLPEIIK DQKAYKEGKL QKALEDAFLA IDAKLTTEEV IKELSQMAGR 120

PQDDEDEKEK VADEDDVDNE EAALLHEEAT MTIEELLTRY GQNCTKNLKH KSLAPAGENA 180

AEGTGKQHDG ESNMNGEADP GDLIDHKERK NGNSDKASTG GNSPALQKPE LGKGDEAVTS 240

STGEAGPSCS STGKPQRTTK SKFFEDSEDE SDEVEEEEED SEECSEDEDG YSSEEAENED 300

DEDDTEEAEE DEDEEEEMLL PGMEGKEEPG SDSGTTAVVA LIRGKQLIVA NAGDSRCVVS 360

EGGKAVDMSY DHKPEDEVEL ARIKNAGGKV TMDGRVNGGL NLSRAIGDHF YKRNKNLPPE 420

EQMISALPDI KVLTINDDHD FMVIACDGIW NVMSSQEVVD FIQSKITQKD ENGVLRPLSS 480

IVEELLDQCL LQTPQGMALA AIT 503

Nucleotide Sequence
(FASTA)

ATGGGCGCGT ACCTTTCGCA GCCCAACACG GTGAAGAGCT CCGGGGATGG GGCCGGGCTC 60

GGGCCGCGCC CGCTGCACTT CGGTTTCAGC GCTATGCAGG GTTGGCGCGT CTCCATGGAG 120

GATGCACACA ACTGCATACC AGAGCTGGAC AGCGAAACAG CCATGTTCTC AGTCTACGAT 180

GGACACGGAG GAGAAGAAGT TGCCCTGTAC TGTGCCAAGT ATCTTCCCGA GATCATCAAG 240

GATCAGAAGG CCTACAAGGA AGGCAAATTG CAAAAGGCCC TGGAAGATGC TTTCTTAGCC 300

ATAGATGCTA AGCTCACCAC TGAGGAGGTG ATTAAAGAGC TCTCTCAGAT GGCTGGGCGA 360

CCCCAAGATG ATGAAGATGA GAAGGAGAAA GTTGCTGACG AAGATGATGT GGATAATGAG 420

GAAGCTGCTC TTCTGCACGA AGAAGCCACA ATGACCATTG AGGAACTTCT CACACGTTAT 480

GGACAAAACT GCACCAAGAA CCTCAAACAC AAGTCCTTAG CTCCGGCTGG GGAGAATGCT 540

GCGGAGGGGA CAGGCAAGCA GCATGATGGG GAGTCAAATA TGAACGGAGA GGCTGACCCA 600

GGGGACCTTA TCGACCACAA GGAGAGGAAG AATGGGAACT CAGACAAAGC CAGCACTGGA 660

GGCAACAGCC CTGCTCTGCA GAAGCCTGAA CTAGGCAAAG GTGACGAGGC CGTCACCTCT 720

TCTACTGGGG AGGCCGGGCC CTCCTGCTCC TCCACGGGAA AGCCCCAGCG CACAACCAAA 780

TCCAAATTTT TTGAGGACAG TGAGGATGAG TCAGATGAGG TTGAGGAAGA GGAGGAAGAC 840

AGTGAGGAAT GCAGTGAAGA TGAGGATGGT TACAGTAGTG AAGAGGCAGA GAATGAAGAT 900

GATGAAGATG ACACTGAAGA AGCAGAGGAG GATGAGGATG AAGAGGAAGA AATGTTGTTA 960

CCAGGCATGG AGGGGAAAGA GGAGCCTGGC TCTGACAGTG GAACGACTGC CGTCGTGGCC 1020

CTCATCCGAG GCAAGCAGCT GATTGTGGCT AATGCTGGAG ACTCTCGCTG CGTGGTGTCG 1080

GAAGGTGGCA AAGCTGTCGA CATGTCGTAT GACCACAAGC CAGAGGATGA GGTAGAACTG 1140

GCCAGGATAA AGAACGCCGG CGGCAAGGTC ACCATGGATG GGAGAGTGAA TGGTGGCCTC 1200

AACCTCTCCA GGGCAATTGG TGATCACTTC TACAAGCGGA ACAAGAATCT GCCTCCAGAA 1260

GAACAGATGA TCTCTGCCTT GCCTGACATC AAAGTGCTGA CAATAAATGA TGACCATGAC 1320

TTCATGGTCA TTGCCTGTGA TGGAATCTGG AATGTGATGA GCAGCCAGGA AGTGGTGGAT 1380

TTCATCCAGT CCAAGATCAC TCAAAAGGAT GAGAATGGAG TCCTGAGGCC GCTCTCCTCC 1440

ATTGTAGAAG AGCTGCTGGA TCAGTGTTTG CTCCAGACAC CTCAGGGGAT GGCACTGGCT 1500

GCGATAACAT GA 1512

Domain Profile

S: 93    leeksldidksGstavvalikdsklyvanvGdSravLcrngkavelssdHkpsredEleR  152

         +e k++  + sG+tavvali++++l+van+GdSr+v + +gkav +s dHkp+ e El+R

Q: 323   MEGKEEPGSDSGTTAVVALIRGKQLIVANAGDSRCVVSEGGKAVDMSYDHKPEDEVELAR  382

         4445455666**************************************************

S: 153   ieeaggsvilkdgaRvlGvLavsRalGdlylk.........pyvtpePevtshrltsede  203

         i++agg+v+ +   Rv+G L++sRa+Gd ++k         +++++ P++ + +++ +++

Q: 383   IKNAGGKVTMDG--RVNGGLNLSRAIGDHFYKrnknlppeeQMISALPDIKVLTINDDHD  440

         ***********9..**********************************************

S: 204   fliLasDGlwdvvsneeavslvrdvle...k  231

         f+++a+DG+w+v+s++e+v+++++ ++   +

Q: 441   FMVIACDGIWNVMSSQEVVDFIQSKITqkdE  471

         ***********************99994330

Domain Sequence
(FASTA)

MEGKEEPGSD SGTTAVVALI RGKQLIVANA GDSRCVVSEG GKAVDMSYDH KPEDEVELAR 60

IKNAGGKVTM DGRVNGGLNL SRAIGDHFYK RNKNLPPEEQ MISALPDIKV LTINDDHDFM 120

VIACDGIWNV MSSQEVVDFI QSKITQKDE 149

Keyword

Complete proteome; Hydrolase; Magnesium; Metal-binding; Protein phosphatase; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005634	; C:nucleus
GO:0046872	; F:metal ion binding
GO:0004722	; F:protein serine/threonine phosphatase activity
GO:0007050	; P:cell cycle arrest
GO:0035970	; P:peptidyl-threonine dephosphorylation

KEGG

InterPros

IPR001932	; PP2C-like.
IPR000222	; PP2C_Mn2_Asp60_BS.
IPR015655	; Protein_Pase_2C.

Pfam

PF00481

; PP2C; 2.

SMARTs

SM00332

; PP2Cc; 1.

Prosites

PS01032

; PP2C; 1.

Prints

Created Date

20-Feb-2013