EKS-GOG-00199

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-GOG-00199

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/RCK	517.5	1.1E-155	4	284	281

Status

Unreviewed

Ensembl Protein

ENSGGOP00000025135

UniProt Accession

G3SAL2;

Protein Name

Protein Synonyms/Alias

Gene Name

ICK

Gene Synonyms/Alias

ICK;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSGGOG00000000189	ENSGGOP00000025135	ENSGGOT00000025159
ENSGGOG00000000189	ENSGGOP00000000186	ENSGGOT00000000191

Organism

Gorilla gorilla

Functional Description

Protein Length

632

Protein Sequence
(FASTA)

MNRYTTIRQL GDGTYGSVLL GRSIESGELI AIKKMKRKFY SWEECMNLRE VKSLKKLNHA 60

NVVKLKEVIR ENDHLYFIFE YMKENLYQLI KERNKLFPES AIRNIMYQIL QGLAFIHKHG 120

FFHRDLKPEN LLCMGPELVK IADFGLAREI RSKPPYTDYV STRWYRAPEV LLRSTNYSSP 180

IDVWAVGCIM AEVYTLRPLF PGASEIDTIF KICQVLGTPK KTDWPEGYQL SSAMNFRWPQ 240

CVPNNLKTLI PNASSEAVQL LRDMLQWDPK KRPTASQALR YPYFQVGHPL GSTTQNLQDS 300

EKPQKGVLEK AGPPPHIKPV PPAQPPTKPH TRISSRQHQA SQPPLHLTYP YKAEVSRTDH 360

PSHLQDKPSP LLFPSLHNKH PQSKITAGLE HKNGEIKPKS RRRWGLISRS TKDSDDWADL 420

DDLDFSPSLS RIDLKNKKRQ SDDTLCRFES VLDLKPSEPV GTGNSAPTQT SYQRRDTPTL 480

RSAAKQHYLK HSRYLPESPK IRNMILSNPG KEFIPPNPWS SSGLSGKSSG TMSVISKVNS 540

VGSSSTSSSG LTGNYVPSFL KKEIGSAMQR VHLAPIPDPS PGYSSLKAMR PHPGRPFFHT 600

QPRSTPGLIP RPPAAQPVHG RTDWASKYAS RR 632

Nucleotide Sequence
(FASTA)

ATGAATAGAT ACACAACAAT CAGGCAGCTC GGCGATGGAA CCTACGGTTC CGTCCTGCTG 60

GGAAGAAGCA TTGAGTCTGG GGAGCTGATC GCTATTAAAA AAATGAAAAG AAAATTTTAT 120

TCCTGGGAGG AATGCATGAA CCTTCGGGAG GTTAAGTCTT TAAAGAAGCT CAACCATGCC 180

AATGTAGTCA AATTAAAAGA AGTTATCAGG GAAAATGATC ATCTTTATTT TATCTTCGAG 240

TACATGAAGG AAAATCTTTA CCAGCTCATT AAAGAGAGAA ATAAGTTGTT TCCTGAGTCT 300

GCTATAAGGA ATATCATGTA TCAGATATTA CAAGGACTCG CATTTATTCA CAAACACGGC 360

TTCTTTCATC GAGACTTAAA GCCTGAGAAC CTCCTCTGCA TGGGACCAGA ACTTGTGAAA 420

ATTGCAGACT TTGGTTTGGC CCGAGAAATA CGATCAAAAC CTCCATATAC AGATTATGTA 480

TCTACCAGAT GGTACAGGGC TCCAGAAGTA CTCCTGAGGT CTACCAACTA CAGCTCCCCC 540

ATTGACGTCT GGGCGGTGGG CTGCATCATG GCAGAAGTTT ACACCCTCAG GCCACTCTTC 600

CCTGGAGCCA GTGAAATTGA CACAATATTC AAAATTTGCC AAGTGCTGGG GACACCAAAA 660

AAGACTGACT GGCCTGAAGG CTATCAACTT TCAAGTGCAA TGAACTTCCG TTGGCCACAG 720

TGTGTACCCA ATAACTTAAA GACCTTGATT CCCAATGCTA GCAGTGAAGC AGTCCAGCTC 780

CTGAGAGACA TGCTTCAGTG GGATCCCAAG AAACGACCAA CAGCTAGTCA GGCACTTCGA 840

TATCCTTACT TCCAAGTTGG ACACCCACTA GGCAGCACCA CACAAAACCT TCAGGATTCA 900

GAAAAACCAC AGAAAGGCGT CCTGGAAAAG GCAGGCCCAC CTCCTCATAT TAAGCCAGTC 960

CCACCTGCCC AGCCGCCAAC CAAGCCACAC ACACGAATTT CTTCACGACA GCATCAAGCC 1020

AGCCAGCCCC CTCTGCATCT CACGTACCCC TACAAAGCAG AGGTCTCCAG GACAGATCAC 1080

CCAAGCCATC TCCAGGACAA GCCAAGCCCG TTGCTTTTCC CGTCCCTCCA CAACAAGCAT 1140

CCCCAGTCGA AAATCACAGC TGGCCTGGAG CACAAAAATG GTGAGATAAA GCCAAAGAGT 1200

AGGAGAAGGT GGGGTCTTAT TTCCAGGTCA ACAAAGGATT CAGATGATTG GGCTGACTTG 1260

GATGACTTGG ATTTCAGTCC ATCCCTCAGC AGGATTGACC TGAAAAACAA GAAAAGACAG 1320

AGTGATGACA CTCTCTGCAG GTTTGAGAGT GTTTTGGACC TGAAGCCCTC TGAGCCTGTG 1380

GGCACAGGAA ACAGTGCCCC CACCCAGACG TCATATCAGC GGCGAGACAC GCCCACCCTG 1440

AGATCTGCAG CCAAGCAGCA CTATTTGAAG CACTCTCGAT ACTTGCCTGA GTCACCCAAG 1500

ATAAGAAATA TGATACTCTC GAATCCAGGC AAGGAATTTA TTCCACCTAA TCCATGGTCT 1560

AGTTCTGGCT TGTCTGGAAA ATCTTCAGGG ACAATGTCAG TAATCAGCAA AGTAAATTCA 1620

GTTGGTTCCA GCTCTACAAG TTCTAGTGGA CTGACTGGAA ACTATGTCCC TTCCTTTCTG 1680

AAAAAAGAAA TCGGTTCTGC TATGCAGAGG GTACACCTAG CACCTATTCC AGACCCTTCC 1740

CCTGGTTATT CCTCCCTGAA GGCCATGAGA CCTCATCCTG GGCGACCATT CTTCCACACC 1800

CAGCCTAGAA GCACTCCTGG GCTGATACCA CGGCCTCCAG CCGCCCAGCC AGTGCATGGC 1860

CGGACAGACT GGGCTTCCAA GTACGCATCT CGGCGATGA 1899

Domain Profile

S: 1     yklikklGdGtfgevllakslktgelvaikkmkrkfesleevtnlrevkslkklnahdni  60

         y++i++lGdGt+g+vll++s+++gel+aikkmkrkf+s+ee++nlrevkslkkln h+n+

Q: 4     YTTIRQLGDGTYGSVLLGRSIESGELIAIKKMKRKFYSWEECMNLREVKSLKKLN-HANV  62

         99*****************************************************.****

S: 61    iklkeviidrendslylvlelmeenlyqlikdrrkllsesklksilyqilkglafihkhg  120

         +klkevi  rend+ly+++e+m+enlyqlik+r+kl++es++++i+yqil+glafihkhg

Q: 63    VKLKEVI--RENDHLYFIFEYMKENLYQLIKERNKLFPESAIRNIMYQILQGLAFIHKHG  120

         *******..***************************************************

S: 121   ffhrdlkPenilikgselvkladfGlarevrsknPytdyvstrwyraPevllrsgvyssp  180

         ffhrdlkPen+l++g+elvk+adfGlare+rsk+PytdyvstrwyraPevllrs++yssp

Q: 121   FFHRDLKPENLLCMGPELVKIADFGLAREIRSKPPYTDYVSTRWYRAPEVLLRSTNYSSP  180

         ************************************************************

S: 181   ldlwavGcvlaevavlrplfPGaseidqifkilevlGtPkkkewdeayklasalnlkfpq  240

         +d+wavGc++aev++lrplfPGaseid+ifki++vlGtPkk++w+e+y+l+sa+n+++pq

Q: 181   IDVWAVGCIMAEVYTLRPLFPGASEIDTIFKICQVLGTPKKTDWPEGYQLSSAMNFRWPQ  240

         ************************************************************

S: 241   vegsslktlvsnaskealellkdllaydPderataqqalkypyf  284

         +++++lktl++nas+ea++ll+d+l++dP++r+ta+qal+ypyf

Q: 241   CVPNNLKTLIPNASSEAVQLLRDMLQWDPKKRPTASQALRYPYF  284

         *******************************************9

Domain Sequence
(FASTA)

YTTIRQLGDG TYGSVLLGRS IESGELIAIK KMKRKFYSWE ECMNLREVKS LKKLNHANVV 60

KLKEVIREND HLYFIFEYMK ENLYQLIKER NKLFPESAIR NIMYQILQGL AFIHKHGFFH 120

RDLKPENLLC MGPELVKIAD FGLAREIRSK PPYTDYVSTR WYRAPEVLLR STNYSSPIDV 180

WAVGCIMAEV YTLRPLFPGA SEIDTIFKIC QVLGTPKKTD WPEGYQLSSA MNFRWPQCVP 240

NNLKTLIPNA SSEAVQLLRD MLQWDPKKRP TASQALRYPY F 281

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gallus gallus"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013