EKS-GOG-00426

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-GOG-00426

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/ULK	355.5	2.5E-106	2	242	241

Status

Unreviewed

Ensembl Protein

ENSGGOP00000026569

UniProt Accession

G3SEN5;

Protein Name

Protein Synonyms/Alias

Gene Name

ULK1

Gene Synonyms/Alias

ULK1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSGGOG00000001320	ENSGGOP00000001307	ENSGGOT00000001332
ENSGGOG00000001320	ENSGGOP00000026569	ENSGGOT00000024267

Organism

Gorilla gorilla

Functional Description

Protein Length

1020

Protein Sequence
(FASTA)

QKHDLEVAVK CINKKNLAKS QTLLGKEIKI LKELKHENIV ALYDFQEMAN SVYLVMEYCN 60

GGDLADYLHA MRTLSEDTIR LFLQQIAGAM RLLHSKGIIH RDLKPQNILL SNPAGRRANP 120

NSIRVKIADF GFARYLQSNM MAATLCGSPM YMAPEVIMSQ HYDGKADLWS IGTIVYQCLT 180

GKAPFQASSP QDLRLFYEKN KTLVPTIPRE TSAPLRQLLL ALLQRNHKDR MDFDEFFHHP 240

FLDASPSVRK SPPVPVPSYP SSGSGSSSSS SSTSHLASPP SLGEMQQLQK TLASPADTAG 300

FLHSSRDSGG SKDSSCDTDD FVMVPAQFPG DLVAEAPSAK PPPDSLMCSG SSLVASAGLE 360

SHGRTPSPSP PCSSSPSPSG RAGPFSSSRC GASVPIPVPT QVQNYQRIER NLQSPTQFQT 420

PRSSAIRRSG STSPLGFARA SPSPPAHAEH GGVLARKMSL GGGRPYTPSP QVGTIPERPG 480

WSGTPSPQGA EMRGGRSPRP GSSAPEHSTR TSGLGCRLHS APNLSDLHVV RPKLPKPPTD 540

PLGAVFSPSQ ASPPQPSHGL QSCRNLRGSP KLPDFLQRNP LPPILGSPTK AVPSFDFPKT 600

PSSQNLLALL ARQGVVMTPP RNRTLPDLSE MGPFHGQPLG PGLRPGEDPK GPFGRSFSTS 660

RLTDLLLKAA FGTQAPDPGS TESLQEKPME IGVWVGGAWR LWDGGTVAAA LLPGRSGLGV 720

GIPRGSLGGH RSPWPEVGSW GLGGCAGPTG SAGSSARHLV PGPCSEAPAP ELPAPGHGCS 780

FADPIAVNLE GAVTFEAPDL PEETLMEQEH TEILRGLRFT LLFVQHVLEI AALKGSASEA 840

AGGPEYQLQE SVVADQISLL SREWGFAEQL VLYLKVAELL SSGLQTAIDQ IRAGKLCLSS 900

TVKQVVRRLN ELYKASVVSC QGLSLRLQRF FLDKQRLLDR IHSITAERLI FSHAVQMVQS 960

AALDEMFQHR EGCVPRYHKA LLLLEGLQHM LSDQADIENV SKCKLCIERR LSALLTGICA 1020

Nucleotide Sequence
(FASTA)

CAGAAGCACG ATTTGGAGGT CGCCGTCAAG TGCATTAACA AGAAGAACCT CGCCAAGTCT 60

CAGACGCTGC TGGGGAAGGA AATCAAAATC CTGAAGGAAC TGAAACATGA AAACATCGTG 120

GCCCTGTACG ACTTCCAGGA AATGGCTAAT TCTGTCTACC TGGTTATGGA GTACTGCAAC 180

GGTGGGGACC TGGCCGACTA CCTGCACGCC ATGCGCACGC TGAGCGAGGA CACCATCAGG 240

CTCTTCCTGC AGCAGATCGC GGGCGCCATG CGGCTTCTGC ACAGCAAAGG CATCATCCAC 300

CGCGACCTGA AGCCGCAGAA CATCCTGCTG TCCAACCCCG CCGGCCGCCG CGCCAACCCC 360

AACAGCATCC GCGTCAAGAT CGCTGACTTC GGCTTCGCGC GGTACCTCCA GAGCAACATG 420

ATGGCGGCCA CACTCTGCGG CTCCCCCATG TACATGGCCC CCGAGGTCAT CATGTCCCAG 480

CACTACGACG GGAAGGCGGA CCTGTGGAGC ATCGGCACCA TCGTCTACCA GTGCCTGACG 540

GGGAAGGCGC CCTTCCAGGC CAGCAGCCCC CAGGACCTGC GCCTGTTCTA CGAGAAGAAC 600

AAGACGTTGG TCCCCACCAT CCCCCGGGAG ACCTCGGCCC CGCTGCGGCA GCTGCTCCTA 660

GCCCTGCTGC AGCGCAACCA CAAGGACCGC ATGGACTTCG ATGAGTTTTT TCATCACCCT 720

TTCCTCGATG CCAGCCCCTC GGTCAGGAAA TCCCCACCCG TGCCTGTGCC CTCGTACCCA 780

AGCTCGGGGT CTGGCAGCAG CTCCAGCAGC AGCTCCACCT CCCACCTGGC CTCCCCGCCG 840

TCCCTGGGCG AGATGCAGCA GCTACAGAAG ACCCTGGCCT CCCCGGCTGA CACCGCTGGC 900

TTCCTGCACA GCTCCCGGGA CTCTGGTGGC AGCAAGGACT CCTCCTGTGA CACAGACGAC 960

TTCGTCATGG TCCCCGCGCA GTTTCCAGGT GACCTGGTGG CTGAGGCGCC CAGTGCCAAA 1020

CCCCCGCCAG ACAGCCTGAT GTGCAGTGGG AGCTCACTGG TGGCCTCTGC GGGCTTGGAG 1080

AGCCACGGCC GGACCCCATC TCCATCCCCA CCCTGCAGCA GCTCCCCCAG TCCCTCAGGT 1140

CGGGCTGGCC CGTTCTCCAG CAGCAGGTGC GGCGCCTCTG TCCCCATCCC AGTCCCCACG 1200

CAGGTGCAGA ACTACCAGCG CATTGAGCGA AACCTGCAGT CACCCACCCA GTTCCAAACA 1260

CCTCGGTCCT CTGCCATCCG CAGGTCAGGC AGCACCAGCC CCCTGGGCTT TGCAAGGGCC 1320

AGCCCCTCGC CCCCTGCCCA CGCTGAGCAT GGAGGCGTCC TGGCCAGGAA GATGTCTCTG 1380

GGTGGAGGCC GGCCCTACAC GCCATCACCT CAAGTTGGAA CCATCCCTGA GCGGCCAGGC 1440

TGGAGCGGGA CGCCCTCCCC ACAGGGAGCT GAGATGCGGG GTGGCAGGTC CCCTCGTCCA 1500

GGCTCCTCTG CACCCGAGCA CTCTACCCGC ACTTCCGGGC TGGGCTGCCG CCTGCACAGT 1560

GCCCCCAACC TGTCTGACTT GCACGTCGTC CGCCCCAAGC TGCCCAAACC CCCCACGGAC 1620

CCCCTGGGAG CTGTGTTCAG CCCATCACAG GCCAGCCCTC CCCAGCCGTC CCACGGCCTG 1680

CAGTCCTGCC GGAACCTGCG GGGCTCACCC AAGCTGCCCG ACTTCCTGCA GCGAAACCCC 1740

CTGCCCCCCA TCCTGGGCTC CCCCACCAAG GCTGTGCCCT CCTTCGACTT CCCGAAGACC 1800

CCCAGCTCCC AGAACCTGCT GGCCCTCCTA GCCCGGCAGG GCGTGGTGAT GACGCCCCCT 1860

CGAAACCGGA CGCTGCCCGA CCTCTCTGAG ATGGGACCCT TCCATGGTCA GCCGTTGGGC 1920

CCTGGCCTGC GGCCAGGAGA GGACCCCAAG GGTCCCTTTG GCCGGTCTTT CAGCACCAGC 1980

CGCCTCACTG ACCTGCTCCT TAAGGCGGCG TTTGGGACAC AAGCCCCGGA CCCGGGCAGC 2040

ACGGAGAGCC TGCAGGAGAA GCCCATGGAG ATCGGTGTGT GGGTGGGTGG GGCTTGGAGG 2100

CTGTGGGACG GGGGTACAGT GGCAGCTGCC CTCCTCCCAG GCAGATCTGG GCTGGGGGTC 2160

GGGATACCCA GAGGGTCCCT TGGTGGGCAC CGCAGCCCTT GGCCTGAGGT GGGGAGCTGG 2220

GGACTTGGGG GTTGTGCAGG CCCCACTGGC TCTGCCGGCT CTTCTGCCCG CCACCTGGTG 2280

CCTGGGCCCT GCAGCGAGGC CCCAGCCCCT GAGCTCCCTG CTCCAGGACA CGGCTGCAGC 2340

TTTGCCGACC CCATTGCTGT GAACCTGGAG GGGGCTGTGA CCTTCGAGGC CCCCGACCTC 2400

CCTGAGGAGA CCCTCATGGA GCAAGAGCAC ACGGAGATCC TGCGTGGCCT GCGCTTCACG 2460

CTGCTGTTCG TGCAGCACGT CCTGGAGATC GCAGCCCTGA AGGGCAGCGC CAGCGAGGCG 2520

GCGGGGGGCC CTGAGTACCA GCTGCAGGAG AGTGTGGTGG CCGACCAGAT CAGCCTGCTG 2580

AGCCGAGAAT GGGGCTTCGC GGAACAGCTG GTGCTGTACC TGAAGGTGGC CGAGCTACTG 2640

TCCTCCGGCC TGCAAACTGC CATCGACCAG ATCCGGGCCG GCAAGCTCTG CCTGTCGTCC 2700

ACCGTGAAGC AGGTGGTGCG CAGGCTGAAT GAGCTGTACA AGGCCAGCGT GGTGTCCTGC 2760

CAGGGCCTGA GCCTGCGGCT GCAGCGCTTC TTCCTGGACA AGCAGCGGCT CCTGGACCGC 2820

ATCCACAGCA TCACTGCCGA GAGACTCATC TTCAGCCACG CTGTGCAAAT GGTGCAGTCG 2880

GCTGCCCTGG ACGAGATGTT CCAGCACCGT GAGGGCTGCG TCCCGCGCTA CCACAAGGCC 2940

CTGCTGCTCC TGGAGGGGCT GCAGCACATG CTCTCGGACC AGGCCGACAT CGAGAACGTC 3000

TCCAAGTGCA AGCTGTGCAT TGAGCGGAGA CTCTCGGCGC TGCTGACTGG CATCTGTGCC 3060

TGA 3063

Domain Profile

S: 23    ktsqvvAikvvekkklkkslenlekeikilkelkhenivalldveetskevylvmeycag  82

         k++ +vA+k+++kk+l+ks++ l keikilkelkhenival+d++e++++vylvmeyc+g

Q: 2     KHDLEVAVKCINKKNLAKSQTLLGKEIKILKELKHENIVALYDFQEMANSVYLVMEYCNG  61

         67899*******************************************************

S: 83    gdLakllkqkkeLsedtvreflqqlasalkaLhskkivhrDlkPqniLlsyadakk.elk  141

         gdLa++l+++++Lsedt+r flqq+a a+++Lhsk+i+hrDlkPqniLls+  +++ + +

Q: 62    GDLADYLHAMRTLSEDTIRLFLQQIAGAMRLLHSKGIIHRDLKPQNILLSNPAGRRaNPN  121

         **************************************************99999999**

S: 142   kvtlkladFglarvlkeesmaatlkGsplYmaPEvvkeqqydakaDlWSiGtilyellvG  201

         ++++k+adFg+ar+l++++maatl+Gsp+YmaPEv+++q+yd kaDlWSiGti+y++l+G

Q: 122   SIRVKIADFGFARYLQSNMMAATLCGSPMYMAPEVIMSQHYDGKADLWSIGTIVYQCLTG  181

         ************************************************************

S: 202   kpPfaaesiseLvekiekndvleppipkeisselkdllqsLLqrdpkkRisfeelfahpf  261

         k+Pf+a+s+++L+ ++ekn++l p+ip+e+s+ l++ll +LLqr++k+R++f+e+f+hpf

Q: 182   KAPFQASSPQDLRLFYEKNKTLVPTIPRETSAPLRQLLLALLQRNHKDRMDFDEFFHHPF  241

         ***********************************************************9

S: 262   l  262

Q: 242   L  242

Domain Sequence
(FASTA)

KHDLEVAVKC INKKNLAKSQ TLLGKEIKIL KELKHENIVA LYDFQEMANS VYLVMEYCNG 60

GDLADYLHAM RTLSEDTIRL FLQQIAGAMR LLHSKGIIHR DLKPQNILLS NPAGRRANPN 120

SIRVKIADFG FARYLQSNMM AATLCGSPMY MAPEVIMSQH YDGKADLWSI GTIVYQCLTG 180

KAPFQASSPQ DLRLFYEKNK TLVPTIPRET SAPLRQLLLA LLQRNHKDRM DFDEFFHHPF 240

L 241

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Dipodomys ordii"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.
IPR022708	; Ser/Thr_kinase_C.

Pfam

PF12063	; DUF3543; 1.
PF00069	; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013