EKS-GOG-00415

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-GOG-00415

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
AGC/SGK	541.0	7.0E-163	98	355	258

Status

Unreviewed

Ensembl Protein

ENSGGOP00000022781

UniProt Accession

G3QGL7;

Protein Name

Protein Synonyms/Alias

Gene Name

SGK1

Gene Synonyms/Alias

SGK1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSGGOG00000001495	ENSGGOP00000022781	ENSGGOT00000031554
ENSGGOG00000001495	ENSGGOP00000001477	ENSGGOT00000001505

Organism

Gorilla gorilla

Functional Description

Protein Length

431

Protein Sequence
(FASTA)

MTVKTEAAKG TLTYSRMRGM VAILIAFMKQ RRMGLNDFIQ KIANNSYACK HPEVQSILKI 60

SQPQEPELMN ANPSPPPSPS QQINLGPSSN PHAKPSDFHF LKVIGKGSFG KVLLARHKAE 120

EVFYAVKVLQ KKAILKKKEE KHIMSERNVL LKNVKHPFLV GLHFSFQTAD KLYFVLDYIN 180

GGELFYHLQR ERCFLEPRAR FYAAEIASAL GYLHSLNIVY RDLKPENILL DSQGHIVLTD 240

FGLCKENIEH NSTTSTFCGT PEYLAPEVLH KQPYDRTVDW WCLGAVLYEM LYGLPPFYSR 300

NTAEMYDNIL NKPLQLKPNI TNSARHLLEG LLQKDRTKRL GAKDDFMEIK SHVFFSLINW 360

DDLINKKITP PFNPNVSGPN DLRHFDPEFT EEPVPNSIGK SPDSVLVTAS VKEAAEAFLG 420

FSYAPPTDSF L 431

Nucleotide Sequence
(FASTA)

ATGACGGTGA AAACTGAGGC TGCTAAGGGC ACCCTCACTT ACTCCAGGAT GAGGGGCATG 60

GTGGCAATTC TCATCGCTTT CATGAAGCAG AGGAGGATGG GTCTGAACGA CTTTATTCAG 120

AAGATTGCCA ATAACTCCTA TGCATGCAAA CACCCTGAAG TTCAGTCCAT CTTGAAAATC 180

TCCCAACCTC AGGAGCCTGA GCTTATGAAT GCCAACCCTT CTCCTCCACC AAGTCCTTCT 240

CAGCAAATCA ACCTTGGCCC GTCGTCCAAT CCTCATGCTA AACCATCTGA CTTTCACTTC 300

TTGAAAGTGA TCGGAAAGGG CAGTTTTGGA AAGGTTCTTC TAGCAAGACA CAAGGCAGAA 360

GAAGTGTTCT ATGCAGTCAA AGTTTTACAG AAGAAAGCAA TCCTGAAAAA GAAAGAGGAG 420

AAGCATATTA TGTCGGAGCG GAATGTTCTG TTGAAGAATG TGAAGCACCC TTTCCTGGTG 480

GGCCTTCACT TCTCTTTCCA GACTGCTGAC AAATTGTACT TTGTCCTAGA CTACATTAAT 540

GGTGGAGAGT TGTTCTACCA TCTCCAGAGG GAACGCTGCT TCCTGGAACC ACGGGCTCGT 600

TTCTATGCTG CTGAAATAGC CAGTGCCTTG GGCTACCTGC ATTCACTGAA CATCGTTTAT 660

AGAGACTTAA AACCAGAGAA TATTTTGCTA GATTCACAGG GACACATTGT CCTTACTGAC 720

TTCGGACTCT GCAAGGAGAA CATTGAACAC AACAGCACAA CATCCACCTT CTGTGGCACG 780

CCGGAGTATC TCGCACCTGA GGTGCTTCAT AAGCAGCCTT ATGACAGGAC TGTGGACTGG 840

TGGTGCCTGG GAGCCGTCTT GTATGAGATG CTGTATGGCC TGCCTCCTTT TTATAGCCGA 900

AACACAGCTG AAATGTATGA CAACATTCTG AACAAGCCCC TCCAGTTGAA ACCAAATATT 960

ACAAATTCCG CAAGACACCT CCTGGAGGGC CTCCTGCAGA AGGACAGGAC AAAGCGGCTC 1020

GGGGCCAAGG ATGACTTTAT GGAGATTAAG AGTCATGTCT TCTTCTCCCT AATTAACTGG 1080

GATGATCTCA TTAATAAGAA GATTACTCCC CCTTTTAACC CAAATGTGAG TGGGCCCAAT 1140

GACCTGCGGC ACTTTGACCC AGAGTTTACC GAAGAGCCTG TCCCCAACTC CATTGGCAAG 1200

TCCCCTGACA GCGTCCTCGT CACAGCCAGC GTCAAGGAAG CTGCCGAGGC TTTCCTAGGC 1260

TTTTCCTATG CGCCTCCCAC GGACTCTTTC CTCTGA 1296

Domain Profile

S: 1     fdflkvigkgsfgkvllakrkadekfyavkvlqkkailkkkeekhimaernvllknvkhp  60

         f+flkvigkgsfgkvlla++ka+e+fyavkvlqkkailkkkeekhim+ernvllknvkhp

Q: 98    FHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKHP  157

         9***********************************************************

S: 61    flvglhysfqtaeklyfvldyvnggelffhlqrersfleprarfyaaeiasalgylhsln  120

         flvglh+sfqta+klyfvldy+nggelf+hlqrer+fleprarfyaaeiasalgylhsln

Q: 158   FLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSLN  217

         ************************************************************

S: 121   ivyrdlkpenilldskghvvltdfglckeeieaedttstfcgtpeylapevlrkkpydrt  180

         ivyrdlkpenillds+gh+vltdfglcke+ie+++ttstfcgtpeylapevl+k+pydrt

Q: 218   IVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNSTTSTFCGTPEYLAPEVLHKQPYDRT  277

         ************************************************************

S: 181   vdwwclgavlyemlyglppfysrdvaemydnilnkplqlkpgisvaalelleellekdrk  240

         vdwwclgavlyemlyglppfysr++aemydnilnkplqlkp+i+++a++lle+ll+kdr+

Q: 278   VDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSARHLLEGLLQKDRT  337

         ************************************************************

S: 241   krlgakedfleiknhvff  258

         krlgak+df+eik+hvff

Q: 338   KRLGAKDDFMEIKSHVFF  355

         *****************9

Domain Sequence
(FASTA)

FHFLKVIGKG SFGKVLLARH KAEEVFYAVK VLQKKAILKK KEEKHIMSER NVLLKNVKHP 60

FLVGLHFSFQ TADKLYFVLD YINGGELFYH LQRERCFLEP RARFYAAEIA SALGYLHSLN 120

IVYRDLKPEN ILLDSQGHIV LTDFGLCKEN IEHNSTTSTF CGTPEYLAPE VLHKQPYDRT 180

VDWWCLGAVL YEMLYGLPPF YSRNTAEMYD NILNKPLQLK PNITNSARHL LEGLLQKDRT 240

KRLGAKDDFM EIKSHVFF 258

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0035091	; F:phosphatidylinositol binding
GO:0004674	; F:protein serine/threonine kinase activity
GO:0007154	; P:cell communication

KEGG

InterPros

IPR000961	; AGC-kinase_C.
IPR011009	; Kinase-like_dom.
IPR001683	; Phox.
IPR017892	; Pkinase_C.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069	; Pkinase; 1.
PF00433	; Pkinase_C; 1.

SMARTs

SM00133	; S_TK_X; 1.
SM00220	; S_TKc; 1.

Prosites

PS51285	; AGC_KINASE_CTER; 1.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013