EKS-GOG-00378

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-GOG-00378

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
STE/STE11	370.7	6.4E-111	363	622	260

Status

Unreviewed

Ensembl Protein

ENSGGOP00000004011

UniProt Accession

G3S871;

Protein Name

Protein Synonyms/Alias

Gene Name

MAP3K3

Gene Synonyms/Alias

MAP3K3;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSGGOG00000004086	ENSGGOP00000004011	ENSGGOT00000004108
ENSGGOG00000004086	ENSGGOP00000024283	ENSGGOT00000031848

Organism

Gorilla gorilla

Functional Description

Protein Length

627

Protein Sequence
(FASTA)

MDEQEALNSI MNDLVALQMN RRHRMPGYET MKNKDTGHSN RQQSDVRIKF EHNGERRIIA 60

FSRPVKYEDV EHKVTTVFGQ PLDLHYMNNE LSILLKNQDD LDKAIDILDR SSSMKSLRIL 120

LLSQDRNHNS SSPHSGVSRQ VRIKASQSAG DINTIYQPPE PRSRHLSVSS QNPGRSSPPP 180

GYVPERQQHI ARQGSYTSIN SEGEFIPETS EQCMLDPLSS AENSLSGSCQ SLDRSADSPS 240

FRKSRMSRAQ SFPDNRQEYS DRETQLYDKG VKGGTYPRRY HVSVHHKDYS DGRRTFPRIR 300

RHQGNLFTLV PSSRSLSTNG ENMGLAVQYL DPRGRLRSAD SENALSVQER NVPTKSPSAP 360

INWRRGKLLG QGAFGRVYLC YDVDTGRELA SKQVQFDPDS PETSKEVSAL ECEIQLLKNL 420

QHERIVQYYG CLRDRAEKTL TIFMEYMPGG SVKDQLKAYG ALTESVTRKY TRQILEGMSY 480

LHSNMIVHRD IKGANILRDS AGNVKLGDFG ASKRLQTICM SGTGMRSVTG TPYWMSPEVI 540

SGEGYGRKAD VWSLGCTVVE MLTEKPPWAE YEAMAAIFKI ATQPTNPQLP SHISEHGRDF 600

LRRIFVEARQ RPSAEELLTH HFAQLMY 627

Nucleotide Sequence
(FASTA)

ATGGACGAAC AGGAGGCATT GAACTCAATC ATGAACGATC TGGTGGCCCT CCAGATGAAC 60

CGACGTCACC GGATGCCTGG ATATGAGACC ATGAAGAACA AAGACACAGG TCACTCAAAT 120

AGGCAGCAGA GTGACGTCAG AATCAAGTTC GAGCACAACG GGGAGAGGCG AATTATAGCG 180

TTCAGCCGGC CTGTGAAATA TGAAGATGTG GAGCACAAGG TGACAACAGT ATTTGGACAA 240

CCTCTTGATC TACATTACAT GAACAATGAG CTCTCCATCC TGCTGAAAAA CCAAGATGAT 300

CTTGATAAAG CAATTGACAT TTTGGATAGA AGCTCAAGCA TGAAAAGCCT TAGGATATTG 360

CTGTTGTCCC AGGACAGAAA CCATAACAGT TCCTCTCCTC ACTCTGGGGT GTCCAGACAG 420

GTGCGGATCA AGGCTTCCCA GTCCGCAGGG GATATAAATA CTATCTACCA GCCCCCCGAG 480

CCCAGAAGCA GGCACCTCTC TGTCAGCTCC CAGAACCCTG GCCGAAGCTC ACCTCCCCCT 540

GGCTATGTTC CTGAGCGGCA GCAGCACATT GCCCGGCAGG GGTCCTACAC CAGCATCAAC 600

AGTGAGGGGG AGTTCATCCC AGAGACCAGC GAGCAGTGCA TGCTGGATCC CCTGAGCAGT 660

GCAGAAAATT CCTTGTCTGG AAGCTGCCAA TCCTTGGACA GGTCAGCAGA CAGCCCATCC 720

TTCCGGAAAT CACGAATGTC CCGTGCCCAG AGCTTCCCTG ACAACAGACA GGAATACTCA 780

GATCGGGAAA CTCAGCTTTA TGACAAAGGG GTCAAAGGTG GAACCTACCC CCGGCGCTAC 840

CACGTGTCTG TGCACCACAA GGACTACAGT GATGGCAGAA GAACATTTCC CCGAATACGG 900

CGTCATCAAG GCAACTTGTT CACCCTGGTG CCCTCCAGCC GCTCCCTGAG CACAAATGGC 960

GAGAACATGG GTCTGGCTGT GCAATACCTG GACCCCCGTG GTCGCCTGCG GAGTGCGGAC 1020

AGCGAGAATG CCCTCTCTGT GCAGGAGAGG AATGTGCCAA CCAAGTCTCC CAGTGCCCCC 1080

ATCAATTGGC GCCGGGGAAA GCTTCTGGGC CAGGGTGCCT TCGGCAGGGT CTATTTGTGC 1140

TATGACGTGG ACACGGGACG TGAACTTGCT TCCAAGCAGG TCCAATTTGA TCCAGACAGT 1200

CCTGAGACAA GCAAGGAGGT GAGTGCTCTG GAGTGCGAGA TCCAGTTGCT AAAGAACTTG 1260

CAGCATGAGC GCATCGTGCA GTACTATGGC TGTCTGCGGG ACCGCGCTGA GAAGACCCTG 1320

ACCATCTTCA TGGAGTACAT GCCAGGGGGC TCGGTGAAAG ACCAGTTGAA GGCTTACGGT 1380

GCTCTGACAG AGAGCGTGAC CCGAAAGTAC ACGCGGCAGA TCCTGGAGGG CATGTCCTAC 1440

CTGCACAGCA ACATGATTGT TCACCGGGAC ATTAAGGGAG CCAACATCCT CCGAGACTCT 1500

GCTGGGAATG TAAAGCTGGG GGACTTTGGG GCCAGCAAAC GCCTGCAGAC GATCTGTATG 1560

TCGGGGACGG GCATGCGCTC CGTCACTGGC ACACCCTACT GGATGAGCCC TGAGGTGATC 1620

AGCGGCGAGG GCTATGGAAG GAAAGCAGAC GTGTGGAGCC TGGGCTGCAC TGTGGTGGAG 1680

ATGCTGACAG AGAAACCACC GTGGGCAGAG TATGAAGCTA TGGCCGCCAT CTTCAAGATT 1740

GCCACCCAGC CCACCAATCC TCAGCTGCCC TCCCACATCT CTGAACATGG CCGGGACTTC 1800

CTGAGGCGCA TTTTTGTGGA GGCTCGCCAG AGACCTTCAG CTGAGGAGCT GCTCACACAC 1860

CACTTTGCAC AGCTCATGTA CTGA 1884

Domain Profile

S: 1     wqkrevigkGsfgsvyaaldvdtgellavKeveikpekksekkevkalkeEikllkelkH  60

         w++++++g+G+fg+vy+++dvdtg+ la K+v+++p++ +++kev+al++Ei+llk+l+H

Q: 363   WRRGKLLGQGAFGRVYLCYDVDTGRELASKQVQFDPDSPETSKEVSALECEIQLLKNLQH  422

         899*********************************************************

S: 61    enivkyyGv..eveeeelkiflEyvegGslssllekygkleesvikkytkqileglayLH  118

         e+iv+yyG+  ++ e++l+if+Ey++gGs++++l++yg+l+esv++kyt+qileg++yLH

Q: 423   ERIVQYYGClrDRAEKTLTIFMEYMPGGSVKDQLKAYGALTESVTRKYTRQILEGMSYLH  482

         *********77778999*******************************************

S: 119   ekkivHRDiKgaNilldssgvvklsDFGaskrlaelntkaaelesltGtlaymaPEvikk  178

         +++ivHRDiKgaNil ds+g+vkl+DFGaskrl++++++ + ++s+tGt+++m+PEvi++

Q: 483   SNMIVHRDIKGANILRDSAGNVKLGDFGASKRLQTICMSGTGMRSVTGTPYWMSPEVISG  542

         **********************************************************99

S: 179   kekgygrkaDiWslgcvviemltgkrPfaeldeelaimfkvgakktkPeipeklseegkd  238

         +  gygrkaD+Wslgc+v+emlt+k+P+ae+ e++a++fk++++ t+P++p+++se+g+d

Q: 543   E--GYGRKADVWSLGCTVVEMLTEKPPWAEY-EAMAAIFKIATQPTNPQLPSHISEHGRD  599

         8..****************************.9***************************

S: 239   flekcleldpkkrpsaeeLLkhef  262

         fl++++ +++++rpsaeeLL+h+f

Q: 600   FLRRIF-VEARQRPSAEELLTHHF  622

         ******.8999***********99

Domain Sequence
(FASTA)

WRRGKLLGQG AFGRVYLCYD VDTGRELASK QVQFDPDSPE TSKEVSALEC EIQLLKNLQH 60

ERIVQYYGCL RDRAEKTLTI FMEYMPGGSV KDQLKAYGAL TESVTRKYTR QILEGMSYLH 120

SNMIVHRDIK GANILRDSAG NVKLGDFGAS KRLQTICMSG TGMRSVTGTP YWMSPEVISG 180

EGYGRKADVW SLGCTVVEML TEKPPWAEYE AMAAIFKIAT QPTNPQLPSH ISEHGRDFLR 240

RIFVEARQRP SAEELLTHHF 260

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>