EKS-GOG-00039

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-GOG-00039

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CK1/VRK	432.2	8.4E-130	37	305	269

Status

Unreviewed

Ensembl Protein

ENSGGOP00000004014

UniProt Accession

G3QNA2;

Protein Name

Protein Synonyms/Alias

Gene Name

VRK1

Gene Synonyms/Alias

VRK1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSGGOG00000004089	ENSGGOP00000004014	ENSGGOT00000004111

Organism

Gorilla gorilla

Functional Description

Protein Length

398

Protein Sequence
(FASTA)

MPRVKAAQAG RQSSAKRHLA EQFAVGEIIT DMAKKEWKVG LPIGQGGFGC IYLADMNSSE 60

SVGSDAPCVV KVEPSDNGPL FTELKFYQRA AKPEQIQKWI RTRKLKYLGV PKYWGSGLHD 120

KNGKSYRFMI MDRFGSDLQK IYEANAKRFS RKTVLQLSLR ILDILEYIHE HEYVHGDIKA 180

SNLLLNYKNP DQVYLVDYGL AYRYCPEGVH KEYKEDPKRC HDGTIEFTSI DAHNGVVVAP 240

SRRGDLEILG YCMIQWLTGH LPWEDNLKDP KYVRDSKIRY RENIASLMDK CFPEKNKPGE 300

IAKYMETVKL LDYTEKPLYE NLRDILLQGL KAIGSKDDGK LDLSVVENGG LKAKTITKKR 360

KKEIEESKEP GVEDMEWSNT QTEEAIQTRS RTRKRVQK 398

Nucleotide Sequence
(FASTA)

ATGCCTCGTG TAAAAGCAGC TCAAGCTGGA AGACAGAGCT CTGCAAAGAG ACATCTTGCA 60

GAACAATTTG CAGTTGGAGA GATAATAACT GACATGGCAA AAAAGGAATG GAAAGTAGGA 120

TTACCCATTG GCCAAGGAGG CTTTGGCTGT ATATATCTTG CTGATATGAA TTCTTCAGAG 180

TCAGTTGGCA GTGATGCACC TTGTGTTGTA AAAGTGGAAC CCAGTGACAA TGGACCTCTT 240

TTTACTGAAT TAAAGTTCTA CCAACGAGCT GCAAAACCAG AGCAAATTCA GAAATGGATT 300

CGTACCCGTA AGCTGAAGTA CCTGGGTGTT CCTAAGTATT GGGGGTCTGG TCTACATGAC 360

AAAAATGGAA AAAGTTACAG GTTTATGATA ATGGATCGCT TTGGGAGTGA CCTTCAGAAA 420

ATATATGAAG CAAATGCCAA AAGGTTTTCT CGGAAAACTG TCTTGCAGCT AAGCTTAAGA 480

ATTCTGGATA TTCTGGAATA TATTCACGAG CATGAGTATG TGCATGGAGA TATCAAGGCC 540

TCAAATCTTC TTCTGAACTA CAAGAATCCT GACCAGGTGT ACTTGGTAGA TTATGGCCTT 600

GCTTATCGGT ACTGCCCAGA AGGAGTTCAT AAAGAATACA AAGAAGACCC CAAAAGATGT 660

CACGATGGCA CTATTGAATT CACGAGCATC GATGCACACA ATGGCGTGGT TGTAGCCCCA 720

TCAAGACGTG GTGATTTGGA AATACTTGGT TATTGCATGA TCCAATGGCT TACTGGCCAT 780

CTTCCTTGGG AGGATAATTT GAAAGATCCT AAATATGTTA GAGATTCCAA AATTAGATAT 840

AGAGAAAATA TTGCAAGTTT GATGGACAAA TGTTTTCCTG AGAAAAACAA ACCAGGTGAA 900

ATTGCCAAAT ACATGGAAAC AGTGAAATTA CTAGACTACA CTGAAAAACC TCTTTATGAA 960

AATTTACGTG ACATTCTTTT GCAAGGACTA AAAGCTATAG GAAGTAAGGA TGATGGCAAA 1020

TTGGACCTCA GTGTTGTGGA GAATGGAGGT TTGAAAGCAA AAACAATAAC AAAGAAGCGA 1080

AAGAAAGAAA TTGAAGAAAG CAAGGAACCT GGTGTTGAAG ATATGGAATG GTCAAACACA 1140

CAGACAGAGG AGGCCATACA GACCCGTTCA AGAACCAGAA AGAGAGTCCA GAAGTAA 1197

Domain Profile

S: 1     wklgkkigkggfGeiyla..ltckkeekdaklvvkvepkenGpLfvelkfyqraakkeqi  58

         wk+g +ig+ggfG+iyla  ++++++++da +vvkvep++nGpLf+elkfyqraak+eqi

Q: 37    WKVGLPIGQGGFGCIYLAdmNSSESVGSDAPCVVKVEPSDNGPLFTELKFYQRAAKPEQI  96

         9*****************99999*************************************

S: 59    kkwkkkkklkllgiPtliasGlhefegekyRflvlprlgrdLqklleqngkrlsektvlq  118

         +kw++++klk+lg+P++++sGlh+++g++yRf++++r+g+dLqk++e+n+kr+s+ktvlq

Q: 97    QKWIRTRKLKYLGVPKYWGSGLHDKNGKSYRFMIMDRFGSDLQKIYEANAKRFSRKTVLQ  156

         ************************************************************

S: 119   lavrlldvleylHeneYvHgdikAanllleeeeasqvyLvdyGlayrycpegkhkeyked  178

         l++r+ld+ley+He+eYvHgdikA+nlll++++++qvyLvdyGlayrycpeg+hkeyked

Q: 157   LSLRILDILEYIHEHEYVHGDIKASNLLLNYKNPDQVYLVDYGLAYRYCPEGVHKEYKED  216

         ************************************************************

S: 179   krraHdGtleftslDaHkGv..apsrRsDleiLgYcllkWltgkLPWeallkdpekvqka  236

         ++r+HdGt+efts+DaH+Gv  apsrR+DleiLgYc+++Wltg+LPWe++lkdp++v+++

Q: 217   PKRCHDGTIEFTSIDAHNGVvvAPSRRGDLEILGYCMIQWLTGHLPWEDNLKDPKYVRDS  276

         *******************6448*************************************

S: 237   kekfldelpellkkllkkkssseelakyl  265

         k ++ +++++l++k++++k++++e+aky+

Q: 277   KIRYRENIASLMDKCFPEKNKPGEIAKYM  305

         ****************************8

Domain Sequence
(FASTA)

WKVGLPIGQG GFGCIYLADM NSSESVGSDA PCVVKVEPSD NGPLFTELKF YQRAAKPEQI 60

QKWIRTRKLK YLGVPKYWGS GLHDKNGKSY RFMIMDRFGS DLQKIYEANA KRFSRKTVLQ 120

LSLRILDILE YIHEHEYVHG DIKASNLLLN YKNPDQVYLV DYGLAYRYCP EGVHKEYKED 180

PKRCHDGTIE FTSIDAHNGV VVAPSRRGDL EILGYCMIQW LTGHLPWEDN LKDPKYVRDS 240

KIRYRENIAS LMDKCFPEKN KPGEIAKYM 269

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>