EKS-GOG-00417

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-GOG-00417

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
AGC/SGK	527.7	7.9E-159	35	292	258

Status

Unreviewed

Ensembl Protein

ENSGGOP00000026548

UniProt Accession

G3QNY0;

Protein Name

Protein Synonyms/Alias

Gene Name

SGK2

Gene Synonyms/Alias

SGK2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSGGOG00000004338	ENSGGOP00000004260	ENSGGOT00000004363
ENSGGOG00000004338	ENSGGOP00000026548	ENSGGOT00000024901

Organism

Gorilla gorilla

Functional Description

Protein Length

367

Protein Sequence
(FASTA)

MNSSPAGTPS PQPSGANGNI NLGPSANPNA RPTDFDFLKV IGKGNYGKVL LAKRKSDGAF 60

YAVKVLQKKS ILKKKEQSHI MAERSVLLKN VRHPFLVGLR YSFQTPEKLY FVLDYVNGGE 120

LFFHLQRERR FLEPRARFYA AEVASAIGYL HSLNIIYRDL KPENILLDCQ GHVVLTDFGL 180

CKEGVEPEDT TSTFCGTPEY LAPEVLRKEP YDRAVDWWCL GAVLYEMLHG LPPFYSQDVS 240

QMYENILHQP LQNPGGRTVA ACDLLQSLLH KDQRQRLGSK ADFLEIKNHV FFSPINWDDL 300

YHKRLTPPFN PNVAGPADLK HFDPEFTQEA VSKSIGCTPD TVASSSGASS AFLGFSYAPE 360

DDDILDC 367

Nucleotide Sequence
(FASTA)

ATGAACTCTA GCCCAGCTGG GACCCCAAGT CCACAGCCCT CCGGGGCCAA TGGGAACATC 60

AACCTGGGGC CTTCAGCCAA CCCAAATGCC CGGCCCACGG ACTTCGACTT CCTCAAAGTC 120

ATCGGCAAAG GGAACTACGG GAAGGTCCTA CTGGCCAAGC GCAAGTCTGA TGGGGCGTTC 180

TATGCAGTGA AGGTACTACA GAAAAAGTCC ATCTTAAAGA AGAAAGAGCA GAGCCACATC 240

ATGGCAGAGC GCAGTGTGCT TCTGAAGAAT GTGCGGCACC CCTTCCTCGT GGGCCTGCGC 300

TACTCCTTCC AGACACCTGA GAAGCTCTAC TTCGTGCTCG ACTATGTCAA CGGGGGAGAG 360

CTCTTCTTCC ACCTGCAGCG GGAGCGCCGG TTCCTGGAGC CCCGGGCCAG GTTCTACGCT 420

GCTGAGGTGG CCAGCGCCAT TGGCTACCTG CACTCCCTCA ACATCATTTA CAGGGACCTG 480

AAACCAGAGA ACATTCTCTT GGACTGCCAG GGACACGTGG TGCTGACGGA TTTTGGCCTC 540

TGCAAGGAAG GTGTAGAGCC TGAAGACACC ACATCCACAT TCTGTGGTAC CCCTGAGTAC 600

TTGGCACCTG AAGTGCTTCG GAAAGAGCCT TATGATCGAG CAGTGGACTG GTGGTGCTTG 660

GGGGCAGTTC TCTACGAGAT GCTCCACGGC CTGCCGCCCT TCTACAGCCA AGACGTATCC 720

CAGATGTATG AGAACATTCT GCACCAGCCG CTACAGAACC CCGGGGGCCG GACGGTGGCC 780

GCCTGTGACC TCCTGCAAAG CCTTCTCCAC AAGGACCAGA GGCAGCGGCT GGGCTCCAAA 840

GCAGACTTTC TTGAGATTAA GAACCATGTA TTCTTCAGCC CCATAAACTG GGATGACCTG 900

TACCACAAGA GGCTAACTCC ACCCTTCAAC CCAAATGTGG CAGGACCTGC TGACTTGAAG 960

CATTTTGACC CAGAGTTCAC CCAGGAAGCT GTGTCCAAGT CCATTGGCTG TACCCCTGAC 1020

ACTGTGGCCA GCAGCTCTGG GGCCTCAAGT GCATTCCTGG GATTTTCTTA TGCGCCAGAG 1080

GATGATGACA TCTTGGATTG CTAG 1104

Domain Profile

S: 1     fdflkvigkgsfgkvllakrkadekfyavkvlqkkailkkkeekhimaernvllknvkhp  60

         fdflkvigkg++gkvllakrk+d++fyavkvlqkk+ilkkke++himaer+vllknv+hp

Q: 35    FDFLKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKSILKKKEQSHIMAERSVLLKNVRHP  94

         9***********************************************************

S: 61    flvglhysfqtaeklyfvldyvnggelffhlqrersfleprarfyaaeiasalgylhsln  120

         flvgl+ysfqt+eklyfvldyvnggelffhlqrer+fleprarfyaae+asa+gylhsln

Q: 95    FLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQRERRFLEPRARFYAAEVASAIGYLHSLN  154

         ************************************************************

S: 121   ivyrdlkpenilldskghvvltdfglckeeieaedttstfcgtpeylapevlrkkpydrt  180

         i+yrdlkpenilld++ghvvltdfglcke++e edttstfcgtpeylapevlrk+pydr+

Q: 155   IIYRDLKPENILLDCQGHVVLTDFGLCKEGVEPEDTTSTFCGTPEYLAPEVLRKEPYDRA  214

         ************************************************************

S: 181   vdwwclgavlyemlyglppfysrdvaemydnilnkplqlkpgisvaalelleellekdrk  240

         vdwwclgavlyeml+glppfys+dv++my+nil++plq ++g++vaa++ll++ll+kd++

Q: 215   VDWWCLGAVLYEMLHGLPPFYSQDVSQMYENILHQPLQNPGGRTVAACDLLQSLLHKDQR  274

         ************************************************************

S: 241   krlgakedfleiknhvff  258

         +rlg+k+dfleiknhvff

Q: 275   QRLGSKADFLEIKNHVFF  292

         *****************9

Domain Sequence
(FASTA)

FDFLKVIGKG NYGKVLLAKR KSDGAFYAVK VLQKKSILKK KEQSHIMAER SVLLKNVRHP 60

FLVGLRYSFQ TPEKLYFVLD YVNGGELFFH LQRERRFLEP RARFYAAEVA SAIGYLHSLN 120

IIYRDLKPEN ILLDCQGHVV LTDFGLCKEG VEPEDTTSTF CGTPEYLAPE VLRKEPYDRA 180

VDWWCLGAVL YEMLHGLPPF YSQDVSQMYE NILHQPLQNP GGRTVAACDL LQSLLHKDQR 240

QRLGSKADFL EIKNHVFF 258

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR000961	; AGC-kinase_C.
IPR011009	; Kinase-like_dom.
IPR017892	; Pkinase_C.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069	; Pkinase; 1.
PF00433	; Pkinase_C; 1.

SMARTs

SM00133	; S_TK_X; 1.
SM00220	; S_TKc; 1.

Prosites

PS51285	; AGC_KINASE_CTER; 1.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013