EKS-GOG-00201

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-GOG-00201

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/RCK	457.5	2.2E-137	4	285	282

Status

Unreviewed

Ensembl Protein

ENSGGOP00000027514

UniProt Accession

G3QTB2;

Protein Name

Protein Synonyms/Alias

Gene Name

MOK

Gene Synonyms/Alias

MOK;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSGGOG00000006052	ENSGGOP00000005925	ENSGGOT00000006083
ENSGGOG00000006052	ENSGGOP00000027514	ENSGGOT00000030585

Organism

Gorilla gorilla

Functional Description

Protein Length

419

Protein Sequence
(FASTA)

MKNYKAIGKI GEGTFSEVMK MQSLRDGNYY ACKQMKQRFE SIEQVNNLRE IQALRRLNPH 60

PNILMLHEVV FDRKSGSLAL ICELMDMNIY ELIRGRRYPL SEKKIMHYMY QLCKSLDHIH 120

RNGIFHRDVK PENILIKQDV LKLGDFGSCR SVYSKQPYTE YISTRWYRAP ECLLTDGFYT 180

YKMDLWSAGC VFYEIASLQP LFPGVNELDQ ISKIHDVIGT PAQKTLTKFK QSRAMNFDFP 240

FKKGSGIPLL TTSLSPQCLS LLHAMVAYDP DERIAAHQAL QHPYFQEQRK TEKRALGSHS 300

KAGFPEHPVA LEPLSNSCQI SKEGRKQKQS LKQEEDRPKR RGPAYVMELP KLKLSGVLRL 360

SSCSSPTLQS VLGSGTNGRV PVLRPLKCIP ASKKTDPRKD LKPAPQQCRL PTIVRKGGR 419

Nucleotide Sequence
(FASTA)

ATGAAGAACT ATAAAGCAAT TGGCAAAATA GGAGAGGGAA CGTTTTCTGA AGTTATGAAG 60

ATGCAAAGCC TGAGAGATGG AAACTACTAT GCATGTAAAC AAATGAAGCA GCGCTTTGAA 120

AGTATTGAGC AAGTCAACAA CCTACGAGAG ATCCAAGCAC TGAGGCGCCT GAATCCGCAC 180

CCAAACATTC TTATGTTGCA TGAAGTGGTT TTTGACAGAA AATCTGGTTC TCTTGCACTA 240

ATATGTGAAC TTATGGACAT GAATATTTAT GAGCTAATAC GAGGGAGAAG ATACCCATTA 300

TCAGAAAAAA AAATTATGCA CTATATGTAC CAGTTATGTA AGTCCCTGGA TCATATTCAC 360

AGAAATGGAA TATTTCACAG AGATGTAAAA CCAGAAAATA TACTAATAAA GCAGGATGTC 420

CTGAAATTAG GGGACTTTGG CTCCTGCCGG AGTGTCTATT CCAAGCAGCC GTACACGGAA 480

TACATCTCCA CCCGCTGGTA CCGGGCCCCG GAGTGTCTCC TCACTGATGG GTTCTACACG 540

TACAAGATGG ACCTGTGGAG CGCTGGCTGT GTGTTCTACG AGATTGCCAG TCTGCAGCCC 600

CTCTTTCCTG GAGTAAATGA ACTGGACCAG ATCTCAAAAA TCCACGATGT CATCGGCACA 660

CCTGCTCAGA AGACCCTCAC CAAGTTCAAA CAGTCGAGAG CTATGAATTT TGATTTTCCT 720

TTTAAAAAGG GATCAGGAAT ACCTCTACTG ACAACCAGTT TGTCCCCACA ATGCCTCTCC 780

CTCCTGCACG CAATGGTGGC CTATGATCCC GATGAGAGAA TCGCCGCCCA CCAGGCCCTG 840

CAGCACCCCT ACTTCCAAGA ACAGAGGAAA ACAGAGAAGC GGGCTCTGGG CAGCCACAGC 900

AAAGCTGGCT TTCCGGAGCA CCCTGTGGCA CTGGAACCAC TCAGTAACAG CTGCCAGATT 960

TCCAAGGAGG GCAGAAAGCA GAAACAGTCC CTAAAGCAAG AGGAGGACCG TCCCAAGAGA 1020

CGAGGACCGG CCTATGTCAT GGAACTGCCC AAACTAAAGC TTTCGGGAGT GCTCAGACTG 1080

TCGTCTTGCT CCAGCCCCAC GCTGCAGTCC GTGCTTGGAT CTGGAACAAA TGGAAGAGTG 1140

CCGGTGCTGA GACCCTTGAA GTGCATCCCT GCGAGCAAGA AGACAGATCC GCGGAAGGAC 1200

CTTAAGCCTG CCCCGCAGCA GTGTCGCCTG CCCACCATAG TGCGGAAAGG CGGAAGATAA 1260

Domain Profile

S: 1     yklikklGdGtfgevllakslktgelvaikkmkrkfesleevtnlrevkslkklnahdni  60

         yk+i k+G+Gtf+ev++++sl++g+++a+k+mk++fes+e+v+nlre+++l++ln+h+ni

Q: 4     YKAIGKIGEGTFSEVMKMQSLRDGNYYACKQMKQRFESIEQVNNLREIQALRRLNPHPNI  63

         99**********************************************************

S: 61    iklkeviidrendslylvlelmeenlyqlikdrrkllsesklksilyqilkglafihkhg  120

         ++l+ev++dr+++sl+l++elm++n+y+li++rr+ lse+k+++++yq++k+l++ih++g

Q: 64    LMLHEVVFDRKSGSLALICELMDMNIYELIRGRRYPLSEKKIMHYMYQLCKSLDHIHRNG  123

         ************************************************************

S: 121   ffhrdlkPenilikgselvkladfGlarevrsknPytdyvstrwyraPevllrsgvyssp  180

         +fhrd+kPenilik ++++kl+dfG++r+v+sk+Pyt+y+strwyraPe+ll++g+y+++

Q: 124   IFHRDVKPENILIK-QDVLKLGDFGSCRSVYSKQPYTEYISTRWYRAPECLLTDGFYTYK  182

         **************.*********************************************

S: 181   ldlwavGcvlaevavlrplfPGaseidqifkilevlGtPkkkewdeayklasalnlkfpq  240

         +dlw++Gcv++e+a+l+plfPG++e+dqi+ki++v+GtP++k++++ +k+++a+n++fp+

Q: 183   MDLWSAGCVFYEIASLQPLFPGVNELDQISKIHDVIGTPAQKTLTK-FKQSRAMNFDFPF  241

         **********************************************.*************

S: 241   vegsslktlvsnaskealellkdllaydPderataqqalkypyf  284

         ++gs+++ l++++s ++l+ll++++aydPder++a+qal++pyf

Q: 242   KKGSGIPLLTTSLSPQCLSLLHAMVAYDPDERIAAHQALQHPYF  285

         *******************************************9

Domain Sequence
(FASTA)

YKAIGKIGEG TFSEVMKMQS LRDGNYYACK QMKQRFESIE QVNNLREIQA LRRLNPHPNI 60

LMLHEVVFDR KSGSLALICE LMDMNIYELI RGRRYPLSEK KIMHYMYQLC KSLDHIHRNG 120

IFHRDVKPEN ILIKQDVLKL GDFGSCRSVY SKQPYTEYIS TRWYRAPECL LTDGFYTYKM 180

DLWSAGCVFY EIASLQPLFP GVNELDQISK IHDVIGTPAQ KTLTKFKQSR AMNFDFPFKK 240

GSGIPLLTTS LSPQCLSLLH AMVAYDPDER IAAHQALQHP YF 282

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona savignyi"; ?>Dasypus novemcinctus"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013