EPS-GOG-00033

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-GOG-00033

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPM/PP2C	192.0	2.1E-56	78	331	254

Status

Unreviewed

Ensembl Protein

ENSGGOP00000007559

UniProt Accession

G3QXL2;

Protein Name

Protein Synonyms/Alias

Gene Name

PPM1E

Gene Synonyms/Alias

PPM1E;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSGGOG00000007728	ENSGGOP00000007559	ENSGGOT00000007761

Organism

Gorilla gorilla

Functional Description

Protein Length

600

Protein Sequence
(FASTA)

NCPSFLAAAL ARATSDEVLQ SDLSAHYIPK ETDGTEGTVE IETVKLARSV FSKLHEICCS 60

WVKDFPLRRR PQLYYETSIH AIKNMRRKME DKHVCIPDFN MLFNLEDQEE QAYFAVFDGH 120

GGVDAAIYAS IHLHVNLVRQ EMFPHDPAEA LCRAFRVTDE RFVQKAARES LRCGTTGVVT 180

FIRGNMLHVA WVGDSQVMLV RKGQAVELMK PHKPDREDEK QRIEALGGCV VWFGAWRVNG 240

SLSVSRAIGD AEHKPYICGD ADSASTVLDG TEDYLILACD GFYDTVNPDE AVKVVSDHLK 300

ENNGDSSMVA HKLVASARDA GSSDNITVIV VFLRDMNKAV NVSEESDWTE NSFQGGQEDG 360

GDDKENHGEC KRPWPQHQCS APADLGYDGR VDSFTDRTSL SPGSQINVLE DPGYLDLTQI 420

EASKPHSAQF LLPVEMFGPG APKKANLINE LMMEKKSVQS SLPEWSGAGE FPTAFNLGST 480

GEQIYRMQSL SPVCSGLENE QFKSPGNRVS RLSHLRHHYS KKWHRFRFNP KFYSFLSAQE 540

PSHKIGTSLS SLTGSGKRNR IRSSLPWRQN SWKGYSENMR KLRKTHDIPC PDLPWSYKIE 600

Nucleotide Sequence
(FASTA)

AATTGCCCTT CCTTTTTGGC TGCTGCTTTA GCCAGAGCCA CATCAGATGA AGTCCTTCAG 60

AGTGATCTTT CTGCACATTA TATCCCAAAG GAAACGGATG GCACAGAAGG GACTGTGGAG 120

ATTGAGACAG TGAAATTGGC CCGTTCTGTC TTCAGCAAAC TACACGAGAT TTGCTGCAGC 180

TGGGTGAAAG ACTTCCCCCT CCGCAGGAGA CCCCAGCTTT ATTATGAGAC ATCAATCCAT 240

GCCATCAAAA ACATGCGCAG GAAAATGGAG GACAAACATG TCTGCATTCC TGACTTTAAT 300

ATGCTCTTCA ACCTAGAGGA CCAGGAAGAA CAAGCTTACT TTGCAGTGTT TGATGGCCAT 360

GGGGGAGTAG ATGCTGCTAT TTATGCCTCC ATTCACCTCC ACGTTAACTT AGTCCGCCAG 420

GAGATGTTCC CCCATGATCC TGCTGAGGCC CTGTGCAGGG CCTTCCGGGT CACTGATGAG 480

CGGTTTGTGC AGAAAGCAGC CAGGGAGAGC TTAAGATGTG GGACCACAGG AGTGGTGACT 540

TTCATCAGAG GCAACATGCT ACATGTGGCC TGGGTGGGTG ATTCCCAGGT TATGCTTGTG 600

AGAAAGGGCC AAGCTGTTGA ACTAATGAAG CCACACAAAC CAGACAGAGA GGATGAAAAG 660

CAGAGAATTG AGGCCCTTGG AGGTTGCGTA GTCTGGTTTG GTGCCTGGAG GGTGAATGGA 720

AGTCTGTCGG TTTCCAGAGC TATTGGAGAT GCTGAACATA AGCCATATAT CTGTGGGGAT 780

GCAGATTCTG CCTCCACTGT TCTGGATGGG ACCGAAGACT ACCTCATTCT GGCCTGTGAT 840

GGCTTCTATG ACACCGTGAA CCCTGATGAG GCAGTGAAAG TTGTGTCCGA CCACCTGAAA 900

GAGAATAACG GAGACAGCAG CATGGTTGCC CACAAATTAG TGGCATCAGC TCGTGATGCT 960

GGGTCAAGTG ATAACATCAC GGTTATTGTG GTATTCCTGA GGGACATGAA CAAAGCTGTA 1020

AATGTTAGTG AGGAATCAGA TTGGACAGAG AACTCTTTTC AAGGAGGGCA AGAAGATGGT 1080

GGGGATGATA AGGAGAATCA TGGAGAGTGC AAACGCCCTT GGCCTCAGCA CCAGTGCTCA 1140

GCACCAGCCG ACCTAGGCTA TGATGGGCGT GTGGATTCAT TCACTGATAG AACTAGCCTG 1200

AGCCCAGGGT CCCAAATCAA CGTGCTGGAA GACCCAGGCT ACCTAGATCT CACACAAATA 1260

GAAGCAAGCA AACCTCACAG TGCCCAGTTT TTGCTACCAG TTGAGATGTT TGGTCCTGGT 1320

GCACCAAAGA AAGCAAATCT TATTAATGAG TTAATGATGG AGAAAAAATC AGTTCAGTCA 1380

TCATTGCCTG AATGGAGTGG TGCTGGAGAG TTTCCCACTG CTTTCAATTT GGGTTCAACA 1440

GGGGAGCAGA TATACAGAAT GCAGAGCTTG TCTCCTGTCT GTTCAGGGTT GGAAAATGAA 1500

CAGTTCAAAT CCCCGGGAAA CAGAGTTTCT AGATTGTCTC ATTTACGCCA CCACTACTCA 1560

AAGAAGTGGC ACAGATTCAG GTTTAATCCA AAGTTTTATT CATTTCTCTC TGCTCAAGAG 1620

CCTTCCCACA AAATAGGCAC TAGCCTGTCC TCACTTACTG GAAGTGGGAA GAGAAATAGG 1680

ATAAGAAGTT CTCTGCCATG GAGGCAAAAT AGTTGGAAAG GGTACAGTGA AAACATGAGG 1740

AAGCTCAGAA AGACTCATGA TATTCCATGC CCAGATCTTC CTTGGAGCTA TAAAATAGAA 1800

TAA 1803

Domain Profile

S: 4     gvvsvngrrnemedavtsspnflkspekkdr..laffgvyDGhggsevakfcseklheil  61

         ++ +++++r++med++   p+f    + +d+   a+f+v+DGhgg ++a ++s +lh  l

Q: 78    SIHAIKNMRRKMEDKHVCIPDFNMLFNLEDQeeQAYFAVFDGHGGVDAAIYASIHLHVNL  137

         567899**************99766555544459************************99

S: 62    aeelesseseerkvkkalakaFlstdeelkvleeksldidksGstavvalikdsklyvan  121

          ++         +  +al +aF  tde++  ++++  ++ ++G+t vv  i+++ l+va

Q: 138   VRQEM----FPHDPAEALCRAFRVTDERF--VQKAARESLRCGTTGVVTFIRGNMLHVAW  191

         99955....6788888999**********..7777788888*******************

S: 122   vGdSravLcrngkavelssdHkpsredEleRieeaggsvilkdga.RvlGvLavsRalGd  180

         vGdS+++L r+g+avel + Hkp+redE++Rie+ gg v+ + ga Rv+G+L vsRa+Gd

Q: 192   VGDSQVMLVRKGQAVELMKPHKPDREDEKQRIEALGGCVV-WFGAwRVNGSLSVSRAIGD  250

         *************************************999.55899**************

S: 181   lylkpyvtpePevtshrltsedefliLasDGlwdvvsneeavslvrdvle.kkeaeqeaa  239

          + kpy+  + +  s+ l+  +++liLa+DG +d+v++ eav++v d+l+ ++ + + +a

Q: 251   AEHKPYICGDADSASTVLDGTEDYLILACDGFYDTVNPDEAVKVVSDHLKeNNGDSSMVA  310

         ************************************************9966778899**

S: 240   kkLvklalargskdnvsaivv  260

         +kLv+ a++ gs+dn+++ivv

Q: 311   HKLVASARDAGSSDNITVIVV  331

         *****************9997

Domain Sequence
(FASTA)

SIHAIKNMRR KMEDKHVCIP DFNMLFNLED QEEQAYFAVF DGHGGVDAAI YASIHLHVNL 60

VRQEMFPHDP AEALCRAFRV TDERFVQKAA RESLRCGTTG VVTFIRGNML HVAWVGDSQV 120

MLVRKGQAVE LMKPHKPDRE DEKQRIEALG GCVVWFGAWR VNGSLSVSRA IGDAEHKPYI 180

CGDADSASTV LDGTEDYLIL ACDGFYDTVN PDEAVKVVSD HLKENNGDSS MVAHKLVASA 240

RDAGSSDNIT VIVV 254

Keyword

Complete proteome; Hydrolase; Magnesium; Metal-binding; Protein phosphatase; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Schizosaccharomyces pombe"; ?>