EKS-GOG-00166

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-GOG-00166

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/TTK	380.0	8.5E-114	527	796	270

Status

Unreviewed

Ensembl Protein

ENSGGOP00000008489

UniProt Accession

G3R014;

Protein Name

Protein Synonyms/Alias

Gene Name

TTK

Gene Synonyms/Alias

TTK;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSGGOG00000008675	ENSGGOP00000008489	ENSGGOT00000008722

Organism

Gorilla gorilla

Functional Description

Protein Length

862

Protein Sequence
(FASTA)

MESEDLSGRE LTIDSIMNKV RDIKNKFKNE DLTDELSLNK ISADTTDNSG TVNQIMMMAN 60

SPEDWLSLLL KLEKNSVPLS DALLNKLIGR YSQAIEALPP DKYGQNESFA RIQVRFAELK 120

AIQEPDDARD YFQMARANCK KFAFVHISFA QFELSQGNVK KSKQLLQKAV ERGAVPLEML 180

EIALRNLNLQ KKQLLSEEEK RNLSASTVLT AQESFSSSLG HLQNRNNSCD SRGQTTKARF 240

LYGENMPPQD AEIGYRNSLR QTNKTKQSCP FGRVPVNLLN SPDCDVKTDD SVVPCFMKRG 300

KRQTSRSECR DLVVPGSKPS GNDSCELRNL KSVQNSHFKE PLVSDEKSSE LIITDSITLK 360

NKTESSLLAK SEETKEYQEP EVPESNQKQW QSKRKSECIN QNPAASSNHW QIPELARKVN 420

TEKHTTFEQP VFSVSKQSPP ISTSKWFDPK SICKTPSSNT LDDYMSCFRT PVVKNDFPPA 480

CQLSTPYGQP ACFQQQQQQI LATPLQNLQV LASSSANECI SVKGRIYSIL KQIGSGGSSK 540

VFQVLNEKKQ IYAIKYVNLE EADNQTLDSY RNEIAYLNKL QQHSDKIIRL YDYEITDQYI 600

YMVMECGNID LNSWLKKKKS IDPWERKSYW KNMLEAVHTI HQHGIVHSDL KPANFLIVDG 660

MLKLIDFGIA NQMQPDTTSI VKDSQVGTVN YMPPEAIKDM SSSRENGKSK SKQLVTHLQD 720

MLKVILISYK VILGKTIFGF IFSQVGKNLI FCLNCNIFIM GLYTHSLFED VLKLCCLKRD 780

PKQRISIPEL LAHPYVQIQT HPGNQMAKGT TEEMKYVLGQ LVGLNSPNSI LKAAKTLYEH 840

YSGGESHNSS SSKTFEKKRG KK 862

Nucleotide Sequence
(FASTA)

ATGGAGTCCG AGGATTTAAG TGGCAGAGAA TTGACAATTG ATTCCATAAT GAACAAAGTG 60

AGAGACATTA AAAATAAGTT TAAAAATGAA GACCTTACTG ATGAACTAAG CTTGAATAAA 120

ATTTCTGCTG ATACTACAGA TAACTCGGGA ACTGTTAACC AAATTATGAT GATGGCAAAC 180

AGCCCAGAGG ACTGGTTGAG TTTGTTGCTC AAACTAGAGA AAAACAGTGT TCCGCTAAGT 240

GATGCTCTTT TAAATAAATT GATTGGTCGT TACAGTCAAG CAATTGAAGC GCTTCCCCCA 300

GATAAATATG GCCAAAATGA GAGTTTTGCT AGAATTCAAG TGAGATTTGC TGAATTAAAA 360

GCTATTCAAG AGCCAGATGA TGCACGTGAC TACTTTCAAA TGGCCAGAGC AAACTGCAAG 420

AAATTTGCTT TTGTTCATAT ATCTTTTGCA CAATTTGAAC TGTCACAAGG TAATGTCAAA 480

AAAAGTAAAC AACTTCTTCA AAAAGCTGTA GAACGTGGAG CAGTACCACT AGAAATGCTG 540

GAAATTGCCC TGCGGAATTT AAACCTCCAA AAAAAGCAGC TGCTTTCAGA GGAGGAAAAG 600

AGGAATTTAT CAGCATCTAC GGTATTAACT GCCCAAGAAT CATTTTCCAG TTCACTTGGG 660

CATTTACAGA ATAGGAACAA CAGTTGTGAT TCCAGAGGAC AGACTACTAA AGCCAGGTTT 720

TTATATGGAG AGAACATGCC ACCACAAGAT GCAGAAATAG GTTATCGGAA TTCATTGAGA 780

CAAACTAACA AAACTAAACA GTCATGCCCA TTTGGAAGAG TCCCAGTTAA CCTTCTAAAT 840

AGCCCAGATT GTGATGTGAA GACAGATGAT TCAGTTGTAC CTTGTTTTAT GAAAAGGGGT 900

AAAAGACAAA CCTCTAGATC AGAATGCCGA GATTTGGTTG TGCCCGGATC TAAACCAAGT 960

GGAAATGATT CCTGTGAATT AAGAAATTTA AAGTCTGTTC AAAATAGTCA TTTCAAGGAA 1020

CCTCTGGTGT CAGATGAAAA GAGTTCTGAA CTTATTATTA CTGATTCAAT AACCCTGAAG 1080

AATAAAACGG AATCAAGTCT TCTAGCTAAA TCAGAAGAAA CTAAAGAGTA TCAAGAACCA 1140

GAGGTTCCAG AGAGTAACCA GAAACAGTGG CAATCTAAGA GAAAGTCAGA GTGTATTAAC 1200

CAGAATCCTG CTGCATCTTC AAATCACTGG CAGATTCCGG AGTTAGCCCG AAAAGTTAAT 1260

ACAGAGAAAC ATACCACTTT TGAGCAACCT GTCTTTTCAG TTTCAAAACA GTCACCACCA 1320

ATATCAACAT CTAAATGGTT TGACCCAAAA TCTATTTGTA AGACACCAAG CAGCAATACC 1380

TTGGATGATT ACATGAGCTG TTTTAGAACT CCAGTTGTAA AGAATGACTT TCCACCTGCT 1440

TGTCAGTTGT CAACACCTTA TGGCCAACCT GCCTGTTTCC AGCAGCAACA GCAGCAAATA 1500

CTTGCCACTC CACTTCAAAA TTTACAGGTT TTAGCATCCT CTTCAGCAAA TGAATGCATT 1560

TCGGTTAAAG GAAGAATTTA TTCCATATTA AAGCAGATAG GAAGTGGAGG TTCAAGCAAG 1620

GTATTTCAAG TGTTGAATGA AAAGAAACAG ATATATGCTA TAAAATATGT GAACTTAGAA 1680

GAAGCAGATA ACCAAACTCT TGATAGTTAC CGGAACGAAA TAGCTTATTT GAATAAACTA 1740

CAACAACACA GTGATAAGAT CATCCGACTT TATGATTATG AAATCACGGA CCAGTACATC 1800

TACATGGTAA TGGAGTGTGG AAATATTGAT CTTAATAGTT GGCTTAAAAA GAAAAAATCC 1860

ATTGATCCAT GGGAACGCAA GAGTTACTGG AAAAATATGT TAGAGGCAGT TCACACAATC 1920

CATCAACATG GCATTGTTCA CAGTGATCTT AAACCAGCTA ACTTTCTGAT AGTTGATGGA 1980

ATGCTAAAGC TAATTGATTT TGGGATTGCA AACCAAATGC AACCAGATAC AACAAGTATT 2040

GTTAAAGATT CTCAGGTTGG CACAGTTAAT TATATGCCAC CAGAAGCAAT CAAAGATATG 2100

TCTTCCTCCA GAGAGAATGG GAAATCTAAG TCAAAGCAGT TAGTAACACA TCTTCAAGAT 2160

ATGTTAAAGG TAATATTAAT TTCATATAAA GTAATTCTGG GGAAAACAAT TTTTGGTTTT 2220

ATATTTTCAC AAGTTGGGAA GAATTTAATA TTTTGTCTTA ATTGCAATAT TTTTATTATG 2280

GGGTTATATA CACATTCATT GTTTGAAGAT GTTTTAAAGC TTTGTTGTTT AAAAAGGGAC 2340

CCAAAACAGA GGATATCCAT TCCTGAGCTC CTGGCTCATC CATATGTTCA AATTCAAACT 2400

CATCCAGGTA ACCAAATGGC CAAGGGAACC ACTGAAGAAA TGAAATATGT TCTGGGCCAA 2460

CTTGTTGGTC TGAATTCTCC TAACTCCATT TTGAAAGCTG CTAAAACTTT ATATGAACAC 2520

TATAGTGGTG GTGAAAGTCA TAATTCTTCA TCATCCAAGA CTTTTGAAAA AAAAAGGGGA 2580

AAAAAATGA 2589

Domain Profile

S: 1     yeilkklGsGGsskvfkvksekkrvyalkvvdleaaddqtidgykneielleklqdqs.k  59

         y+ilk++GsGGsskvf+v++ekk++ya+k+v+le+ad+qt+d+y+nei++l+klq++s k

Q: 527   YSILKQIGSGGSSKVFQVLNEKKQIYAIKYVNLEEADNQTLDSYRNEIAYLNKLQQHSdK  586

         99********************************************************9*

S: 60    virlydyeledsllylvmecGdidlnkilkkkksiepdyelvsyykemleavkvihqhGi  119

         +irlydye++d+++y+vmecG+idln++lkkkksi+p +e++sy+k+mleav++ihqhGi

Q: 587   IIRLYDYEITDQYIYMVMECGNIDLNSWLKKKKSIDP-WERKSYWKNMLEAVHTIHQHGI  645

         *************************************.**********************

S: 120   vhsdlkPanfllvdGilklidfGianavaedttsivkesqvGtvnylaPealkdmsssqs  179

         vhsdlkPanfl+vdG+lklidfGian++++dttsivk+sqvGtvny++Pea+kdmsss

Q: 646   VHSDLKPANFLIVDGMLKLIDFGIANQMQPDTTSIVKDSQVGTVNYMPPEAIKDMSSS--  703

         *********************************************************9..

S: 180   sereaekskikvsrksdvwslGcilylllygktPfgsirnqvskllaiinPdveiefPei  239

          e+ ++ksk  v++  d+  +  i y+++ gkt fg i +qv k l i   + +i

Q: 704   RENGKSKSKQLVTHLQDMLKVILISYKVILGKTIFGFIFSQVGKNL-IFCLNCNIFIM--  760

         66777778888******************************98844.44444444332..

S: 240   tsniekslvellk.aclkrnPkkrisvdellsspfv  274

           + +    ++lk +clkr+Pk+ris++ell++p+v

Q: 761   GLYTHSLFEDVLKlCCLKRDPKQRISIPELLAHPYV  796

         2234556678888799******************96

Domain Sequence
(FASTA)

YSILKQIGSG GSSKVFQVLN EKKQIYAIKY VNLEEADNQT LDSYRNEIAY LNKLQQHSDK 60

IIRLYDYEIT DQYIYMVMEC GNIDLNSWLK KKKSIDPWER KSYWKNMLEA VHTIHQHGIV 120

HSDLKPANFL IVDGMLKLID FGIANQMQPD TTSIVKDSQV GTVNYMPPEA IKDMSSSREN 180

GKSKSKQLVT HLQDMLKVIL ISYKVILGKT IFGFIFSQVG KNLIFCLNCN IFIMGLYTHS 240

LFEDVLKLCC LKRDPKQRIS IPELLAHPYV 270

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>