EPS-GOG-00032

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-GOG-00032

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPM/PP2C	192.2	1.9E-56	776	1022	247

Status

Unreviewed

Ensembl Protein

ENSGGOP00000024070

UniProt Accession

G3R0G5;

Protein Name

Protein Synonyms/Alias

Gene Name

PHLPP2

Gene Synonyms/Alias

PHLPP2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSGGOG00000008841	ENSGGOP00000024070	ENSGGOT00000034393
ENSGGOG00000008841	ENSGGOP00000008650	ENSGGOT00000008886

Organism

Gorilla gorilla

Functional Description

Protein Length

1314

Protein Sequence
(FASTA)

MKRNGSRNCL NRRSRFGSRE RDWLREDVKR GCVYLYGADT TTATTTTTDL HLVLCTVETP 60

ASEICAGERR ESLYLQLHGD LVRRLEPTER PLQIVYDYLS RLGFDDPVRI QEEATNPDLG 120

CMIRFYGEKP CHMDHLDRIL LSGIYNVRKG KTQLHKWAER LVVLCGTCLI VSSVKDCQTG 180

KMHILPLVGG KIEEVKRRQY SLAFSSAGAQ AQTYHVSFET LAEYQRWQRQ ASKVVSQRIS 240

TVDLSCYSLE EVPEHLFYSQ DITYLNLRHN FMQLERPGGL DTLYKFSQLK GLNLSHNKLG 300

LFPILLCEIS TLTELNLSCN GFHDLPSQIG NLLNLQTLCL DGNFLTTLPE ELGNLQQLSS 360

LGISFNNFSQ IPEVYEKLTM LDRVVMAGNC LEVLNLGVLN RMNHIKHVDL RMNHLKTMVI 420

ENLEGNKHVT HVDLRDNRLT DLDLSSLCSL EQLHCGRNQL RELTLSGFSL RTLYASSNRL 480

TSVNVYPVPS LLTSLDLSRN LLECVPDWAC EAKKIEVLDV SYNLLTEVPG SPLRILSSLS 540

LRKLMLGHNH VQNLPTLVEH IPLEVLDLQH NALTRLPDTL FSKALNLRYL NASANSLESL 600

PSACTEEESL SMLQLLYLTN NLLTDQCIPV LVGHLHLRIL HLANNQLQTF PASKLNKLEQ 660

LEELNLSGNK LKTIPTTIAN CKRLHTLVAH SNNISIFPEI LQLPQIQFVD LSCNDLTEIL 720

IPEALPATLQ DLDLTGNTNL VLEHKTLDIF SHITTLKIDQ KPLPTTDSTV TSTFWSHGLA 780

EMAGQRNKLC VSALAMDSFA EGVGAVYGMF DGDRNEELPR LLQCTMADVL LEEVQQSTND 840

TVFMANTFLV SHRKLGMAGQ KLGSSALLCY IRPDTADPAS SFSLTVANVG TCQAVLCRGG 900

KPVPLSKVFS LEQDPEEAQR VKDQKAIITE DNKVNGVTCC TRMLGCTYLY PWILPKPHIS 960

STPLTIQDEL LILGNKALWE HLSYTEAVNA VRHVQDPLAA AKKLCTLAQS YGCQDNVGAM 1020

VVYLNIGEEG CTCEMNGLTL PGPVGFASTT TIKDAPKPAT PSSSSGIASE FSSEISTSEV 1080

SSEVGSTASD EHNAGGLDTA LLPRPERRCS LHPTPTFGLF QRQPSCATFS SNQSDNGLDS 1140

DDDQPVEGVI TNGSKVEVEV DIHCCRGRDL ENSPPLVESS PTPCSEEHAR GSCFGIRRQN 1200

SVNSGILLPM SKDRMELQKS PSTSCLYGKK LSNGSIVPLE DSLNLIEVAT EVPKRKTGYF 1260

AAPTQMEPED QFVVPRDLEE EVKEQMKQHQ DSRLEPEPHE EDRTEPPEEF DTAL 1314

Nucleotide Sequence
(FASTA)

ATGAAACGCA ATGGGAGCAG AAATTGTTTG AATAGGAGAA GTAGGTTTGG TTCTCGAGAA 60

AGAGACTGGT TAAGAGAAGA TGTAAAGAGA GGCTGTGTTT ACCTTTATGG AGCAGACACT 120

ACCACTGCCA CTACAACCAC CACCGACTTA CATCTCGTCC TTTGCACTGT AGAGACACCA 180

GCATCAGAAA TATGTGCTGG AGAGAGAAGA GAAAGTCTTT ATTTACAGCT TCATGGAGAC 240

CTGGTCAGGA GACTGGAACC TACTGAACGA CCTCTTCAGA TCGTTTATGA TTACTTATCC 300

AGGCTGGGAT TTGATGATCC TGTGCGCATA CAGGAGGAGG CTACAAATCC TGACCTCGGC 360

TGTATGATTC GATTTTATGG TGAAAAACCA TGCCACATGG ATCATTTGGA TCGAATCCTA 420

TTGTCTGGCA TCTATAATGT ACGCAAGGGA AAGACCCAGC TGCATAAGTG GGCTGAGCGC 480

CTAGTTGTCC TCTGTGGTAC CTGCCTTATC GTTTCCTCAG TGAAAGATTG TCAAACTGGA 540

AAGATGCACA TTTTGCCTCT GGTTGGTGGA AAGATAGAAG AAGTGAAGCG ACGGCAATAC 600

TCCCTTGCTT TCAGCTCAGC AGGAGCCCAA GCTCAGACCT ATCATGTCAG CTTCGAGACT 660

TTGGCCGAGT ACCAGCGATG GCAACGGCAA GCATCCAAGG TGGTGTCCCA GCGAATCAGT 720

ACCGTGGATC TCTCGTGTTA CAGCCTCGAG GAGGTTCCTG AGCATCTCTT CTATAGTCAA 780

GATATTACCT ACCTCAACTT GCGACACAAC TTCATGCAGT TAGAAAGACC CGGAGGCCTC 840

GATACACTCT ACAAATTTTC TCAACTGAAG GGCCTGAACT TGTCCCATAA TAAACTTGGG 900

TTGTTTCCTA TATTGTTATG CGAGATCTCT ACCCTGACTG AGCTCAACCT TTCCTGTAAT 960

GGATTTCATG ACCTACCAAG TCAAATTGGC AATCTGCTAA ATCTTCAAAC CCTCTGTCTT 1020

GATGGCAACT TTCTGACTAC TTTACCTGAA GAATTGGGAA ATCTACAACA GCTTTCCTCC 1080

TTGGGAATTT CCTTCAACAA CTTTAGTCAA ATTCCTGAGG TTTATGAGAA ACTAACTATG 1140

TTAGATAGAG TGGTTATGGC AGGAAATTGC CTGGAAGTCC TGAACTTAGG GGTGCTAAAT 1200

AGGATGAACC ATATCAAGCA TGTGGATTTA AGGATGAACC ATTTGAAAAC CATGGTTATT 1260

GAAAATCTGG AGGGAAATAA ACACGTCACC CACGTGGATC TGCGGGACAA CCGACTGACT 1320

GACTTGGATC TTAGCTCCTT ATGCAGCTTG GAACAGCTGC ACTGTGGGCG GAATCAGCTG 1380

AGGGAGCTAA CACTCAGTGG CTTTTCCCTT CGGACCCTCT ATGCCAGTTC CAACAGGCTG 1440

ACATCAGTGA ACGTCTATCC AGTACCCAGC CTGCTCACTT CCTTGGATCT CTCCCGAAAC 1500

CTGCTAGAGT GTGTCCCTGA CTGGGCCTGT GAAGCAAAGA AGATAGAAGT ATTAGATGTG 1560

AGCTATAATC TTCTCACAGA GGTTCCCGGT TCCCCCCTTA GAATTCTGAG TAGCTTGAGT 1620

CTTAGAAAAC TGATGCTGGG ACACAATCAC GTGCAAAACC TTCCAACACT GGTAGAGCAC 1680

ATCCCCCTCG AGGTGTTGGA TCTTCAGCAT AATGCACTCA CGAGGCTGCC AGACACCCTC 1740

TTCTCCAAGG CCTTAAATCT CAGATACTTG AATGCATCTG CAAATAGTCT GGAGTCTTTA 1800

CCATCCGCCT GCACTGAAGA GGAGAGTTTG AGTATGCTGC AGCTGCTTTA TCTGACCAAC 1860

AATCTCCTGA CGGATCAGTG CATACCTGTC CTGGTAGGGC ACCTGCACCT GCGAATCTTG 1920

CATCTTGCAA ACAATCAGTT ACAGACCTTT CCTGCAAGCA AACTAAATAA ATTGGAGCAA 1980

TTGGAGGAAC TGAACCTAAG TGGCAACAAG CTTAAAACCA TTCCCACAAC CATAGCAAAC 2040

TGCAAAAGGC TGCACACCCT TGTTGCACAC TCCAACAACA TCAGCATTTT CCCAGAAATA 2100

CTGCAGTTGC CTCAGATCCA GTTTGTAGAC CTAAGTTGCA ACGACTTGAC AGAAATCCTG 2160

ATTCCAGAGG CTTTGCCTGC TACATTACAG GACCTTGACC TGACTGGAAA TACAAATCTG 2220

GTTCTGGAAC ACAAGACACT GGACATATTT AGCCATATCA CAACCCTGAA AATTGATCAG 2280

AAACCTTTGC CAACCACAGA TTCTACAGTT ACGTCAACCT TCTGGAGCCA TGGACTGGCT 2340

GAGATGGCAG GGCAGAGAAA TAAGCTGTGT GTCTCAGCAC TTGCTATGGA TAGCTTTGCA 2400

GAGGGGGTGG GAGCTGTGTA TGGCATGTTT GATGGAGACC GAAATGAGGA GCTCCCGCGC 2460

CTGCTGCAGT GTACGATGGC AGATGTGCTT TTAGAAGAGG TACAGCAGTC AACTAATGAC 2520

ACAGTTTTCA TGGCTAACAC CTTCTTGGTA TCTCACAGGA AATTAGGAAT GGCTGGCCAG 2580

AAGTTGGGCT CCTCCGCTCT CCTGTGCTAC ATCCGCCCTG ACACTGCCGA TCCAGCAAGT 2640

AGCTTTAGCT TGACTGTAGC CAATGTTGGC ACGTGCCAAG CAGTCCTGTG CCGAGGTGGG 2700

AAGCCAGTGC CCCTCTCTAA AGTCTTCAGC CTGGAGCAGG ACCCAGAGGA GGCGCAAAGG 2760

GTGAAGGACC AAAAAGCCAT CATCACAGAG GACAACAAAG TGAATGGGGT AACCTGCTGT 2820

ACCCGGATGC TGGGCTGTAC ATACCTCTAC CCTTGGATCC TCCCCAAGCC CCACATATCT 2880

TCCACTCCTC TGACCATTCA AGATGAGTTG CTGATTCTGG GAAACAAAGC ATTGTGGGAA 2940

CACTTGTCCT ACACAGAAGC TGTCAATGCT GTACGTCATG TACAAGACCC ATTAGCAGCT 3000

GCTAAGAAGC TGTGCACATT AGCGCAGAGC TATGGCTGTC AGGACAATGT AGGGGCAATG 3060

GTAGTTTATT TGAATATTGG TGAGGAAGGC TGCACTTGTG AAATGAATGG GCTCACCCTC 3120

CCAGGTCCTG TGGGATTTGC TTCAACCACC ACTATCAAGG ATGCCCCTAA GCCAGCCACT 3180

CCATCCTCTA GCAGTGGGAT TGCCTCTGAG TTCAGCAGTG AGATATCCAC CTCAGAGGTG 3240

AGCAGTGAAG TGGGGTCCAC TGCTTCTGAT GAGCATAATG CTGGGGGCCT GGACACTGCC 3300

TTGCTTCCGA GGCCAGAGCG GCGCTGCAGC CTCCACCCAA CACCCACTTT TGGGCTGTTT 3360

CAGCGCCAGC CTTCTTGTGC TACCTTCTCC AGTAACCAGT CTGACAACGG CCTGGACAGT 3420

GATGATGACC AGCCCGTCGA GGGGGTCATA ACCAATGGCA GCAAGGTAGA GGTGGAAGTA 3480

GACATCCACT GCTGCAGGGG GAGGGATCTG GAGAACTCAC CCCCTCTCGT AGAGAGTTCT 3540

CCTACCCCGT GTTCTGAGGA ACATGCTAGA GGGTCGTGTT TTGGGATCCG AAGACAGAAC 3600

AGTGTGAATA GTGGCATACT CCTGCCAATG AGCAAGGACA GGATGGAGTT ACAGAAGTCT 3660

CCCTCCACCT CCTGCCTCTA TGGGAAGAAA CTCTCCAATG GCTCTATTGT GCCCCTAGAG 3720

GACAGCCTGA ACCTCATTGA AGTGGCCACA GAAGTGCCCA AGAGGAAAAC TGGCTATTTT 3780

GCTGCCCCCA CTCAGATGGA ACCAGAGGAC CAGTTTGTTG TGCCTCGTGA CCTGGAAGAA 3840

GAAGTGAAGG AACAAATGAA ACAGCACCAG GACAGCCGGC TCGAGCCTGA GCCCCATGAA 3900

GAGGATCGGA CCGAGCCCCC GGAGGAGTTT GACACAGCAC TATGA 3945

Domain Profile

S: 2     lvgvvsvngrrnemedavtsspnflkspekkdrlaffgvyDGhggsevakfcseklheil  61

         ++g++++ g+rn+++ ++ ++++f++  +     a++g++DG++++e  + +++++ ++l

Q: 776   SHGLAEMAGQRNKLCVSALAMDSFAEGVG-----AVYGMFDGDRNEELPRLLQCTMADVL  830

         6899********************99877.....59************************

S: 62    aeelesseseerkvkkalakaFlstdeelkvleeksldidksGstavvalikds......  115

          ee++    ++++ + ++a++Fl  +++l       ++ +k Gs+a++++i+++

Q: 831   LEEVQ----QSTNDTVFMANTFLVSHRKL------GMAGQKLGSSALLCYIRPDtadpas  880

         ***99....77888889************......89***************99999***

S: 116   ..klyvanvGdSravLcrngkavelssdHkpsre.dEleRieeaggsvilkdgaRvlGvL  172

           +l+vanvG ++avLcr+gk+v+ls+ ++ +++ +E +R++++++ +++++  +v+Gv+

Q: 881   sfSLTVANVGTCQAVLCRGGKPVPLSKVFSLEQDpEEAQRVKDQKAIITEDN--KVNGVT  938

         ******************************99866**********9999998..******

S: 173   avsRalGdlylkpyvtpePevtshrltsedefliLasDGlwdvvsneeavslvrdvlekk  232

         +++R+lG++yl+p++ p+P+++s++lt +de liL+ + lw+++s  eav++vr+v +

Q: 939   CCTRMLGCTYLYPWILPKPHISSTPLTIQDELLILGNKALWEHLSYTEAVNAVRHVQD--  996

         **********************************************************..

S: 233   eaeqeaakkLvklalargskdnvsaivv  260

           + +aakkL++la+++g++dnv a+vv

Q: 997   --PLAAAKKLCTLAQSYGCQDNVGAMVV  1022

         ..************************97

Domain Sequence
(FASTA)

SHGLAEMAGQ RNKLCVSALA MDSFAEGVGA VYGMFDGDRN EELPRLLQCT MADVLLEEVQ 60

QSTNDTVFMA NTFLVSHRKL GMAGQKLGSS ALLCYIRPDT ADPASSFSLT VANVGTCQAV 120

LCRGGKPVPL SKVFSLEQDP EEAQRVKDQK AIITEDNKVN GVTCCTRMLG CTYLYPWILP 180

KPHISSTPLT IQDELLILGN KALWEHLSYT EAVNAVRHVQ DPLAAAKKLC TLAQSYGCQD 240

NVGAMVV 247

Keyword

Complete proteome; Leucine-rich repeat; Reference proteome; Repeat.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>