EKS-GOG-00399

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-GOG-00399

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
TKL/IRAK	317.8	8.5E-95	189	453	265

Status

Unreviewed

Ensembl Protein

ENSGGOP00000020959

UniProt Accession

G3RYR9;

Protein Name

Protein Synonyms/Alias

Gene Name

IRAK4

Gene Synonyms/Alias

IRAK4;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSGGOG00000008989	ENSGGOP00000020959	ENSGGOT00000025820
ENSGGOG00000008989	ENSGGOP00000008789	ENSGGOT00000009028

Organism

Gorilla gorilla

Functional Description

Protein Length

461

Protein Sequence
(FASTA)

MNKPITPSTY VRCLNVGLIR KLSDFIDPQE GWKKLAVAIK KPSGDDRYNQ FHIRRFEALL 60

QTGKSPTSEL LFDWGTTNCT VGDLVDLLIQ NEFFAPASLL LPDAVPKTAN TLPSKEAVTV 120

QQKQMPFDDK DRTLMTPVQN LEQSYMPPDS SSPENKSLEV SDTRFHSFSF YELKNVTNNF 180

DERPISVGGN KMGEGGFGVV YKGYVNNTTV AVKKLAAMVD ITTEELKQQF DQEIKVMAKI 240

HERSIVEIRM YSNYGDDVCF QTLLVPYLHL ISLLDCRDGT PPLSWHMRCK IAQGAANGIN 300

FLHENHHIHR DIKSANILLD EAFTAKISDF GLARASEKFA QTVMTSRIVG TTAYMAPEAL 360

RGEITPKSDI YSFGVVLLEI ITGLPAVDEH REPQLLLDIK EEIEDEEKTI EDYIDKKMND 420

ADSTSVETMY SVASQCLHEK KNKRPDNKKK VQQLLQEMTA S 461

Nucleotide Sequence
(FASTA)

ATGAACAAAC CCATAACACC ATCAACATAT GTGCGCTGCC TCAATGTTGG ACTAATTAGG 60

AAGCTGTCAG ATTTTATTGA TCCTCAAGAA GGATGGAAGA AGTTAGCTGT AGCTATTAAA 120

AAACCATCTG GTGATGATAG ATACAATCAG TTTCACATAA GGAGATTTGA AGCATTACTT 180

CAAACTGGAA AAAGTCCCAC TTCTGAATTA CTGTTTGACT GGGGCACCAC AAATTGCACA 240

GTTGGTGATC TTGTGGATCT TTTGATCCAA AATGAATTTT TTGCTCCTGC GAGTCTTTTG 300

CTCCCAGATG CTGTTCCCAA AACTGCTAAT ACACTACCTT CTAAAGAAGC TGTAACAGTT 360

CAGCAAAAAC AGATGCCTTT CGATGACAAA GACAGGACAT TGATGACACC TGTGCAGAAT 420

CTTGAACAAA GCTATATGCC ACCTGACTCC TCAAGTCCAG AAAATAAAAG TTTAGAAGTT 480

AGTGATACAC GTTTTCACAG TTTTTCATTT TATGAATTGA AGAATGTCAC AAATAACTTT 540

GATGAACGAC CCATTTCTGT TGGTGGTAAC AAAATGGGAG AGGGAGGATT TGGAGTTGTA 600

TATAAAGGCT ACGTAAATAA CACAACTGTG GCAGTGAAGA AGCTTGCAGC AATGGTTGAC 660

ATTACTACTG AAGAACTGAA ACAGCAGTTT GATCAAGAAA TAAAAGTAAT GGCAAAAATT 720

CATGAGAGAT CAATTGTAGA GATACGAATG TATTCTAATT ATGGTGATGA TGTGTGTTTT 780

CAAACTTTAC TGGTTCCTTA CCTTCATTTA ATATCATTAT TAGATTGTAG GGATGGTACT 840

CCACCACTTT CTTGGCACAT GAGATGCAAG ATTGCTCAGG GTGCAGCTAA TGGCATCAAT 900

TTTCTACATG AAAATCATCA TATTCATAGA GATATTAAAA GTGCAAATAT CTTACTAGAT 960

GAAGCTTTTA CTGCTAAAAT ATCTGACTTT GGCCTTGCCC GGGCTTCTGA GAAGTTTGCC 1020

CAGACAGTCA TGACTAGCAG AATTGTGGGA ACAACAGCTT ATATGGCACC AGAAGCTTTG 1080

CGTGGAGAAA TAACACCCAA ATCCGATATT TACAGCTTTG GTGTGGTTTT ACTAGAAATA 1140

ATAACTGGAC TTCCAGCTGT GGATGAACAC CGTGAACCTC AGTTATTGCT AGATATTAAA 1200

GAAGAAATTG AAGATGAAGA AAAGACAATT GAAGATTATA TTGATAAAAA GATGAATGAT 1260

GCTGATTCCA CTTCAGTTGA AACTATGTAC TCTGTTGCTA GTCAATGTCT GCATGAAAAG 1320

AAAAATAAGA GACCAGACAA TAAGAAGAAG GTTCAACAGC TGCTGCAAGA GATGACAGCT 1380

TCTTAA 1386

Domain Profile

S: 4     dnrigeGgfgevyrgelkntavavkklkeeadlslkelkqsfltElkvlarfrHdnilel  63

         +n++geGgfg+vy+g ++nt+vavkkl++++d++++elkq+f++E+kv+a+++   i+e+

Q: 189   GNKMGEGGFGVVYKGYVNNTTVAVKKLAAMVDITTEELKQQFDQEIKVMAKIHERSIVEI  248

         79**********************************************************

S: 64    lgysaeseklcLvYqymknGsLedrLqcqkgsepLsWpqRlsillGtaraiefLHeasps  123

           ys  ++++c+   +++   L   L c++g++pLsW++R++i++G+a++i+fLHe+  +

Q: 249   RMYSNYGDDVCFQTLLVPYLHLISLLDCRDGTPPLSWHMRCKIAQGAANGINFLHEN--H  306

         ***********8888888888888899******************************..*

S: 124   lihgdiksaNiLLDekltpKlgDfglarfapesekqsstvlrtskvrgtlaYlpeefirv  183

         +ih+diksaNiLLDe++t+K++Dfglar   +sek ++tv+ ts+++gt+aY+++e++r

Q: 307   HIHRDIKSANILLDEAFTAKISDFGLAR---ASEKFAQTVM-TSRIVGTTAYMAPEALR-  361

         ****************************...9********9.*****************.

S: 184   gqltvkvDvySfGiVllEvltGlravdedrktkyLkdllkeeieeekveilekfldkkag  243

         g++t k+D+ySfG+VllE++tGl+avde+r+++ L+d+ keeie+e+ +++e+++dkk++

Q: 362   GEITPKSDIYSFGVVLLEIITGLPAVDEHREPQLLLDI-KEEIEDEE-KTIEDYIDKKMN  419

         *************************************9.********.9***********

S: 244   kleeellealielalaclaekakkrPtmsqvlel  277

         +++++++e+++++a++cl+ek++krP+ ++ +++

Q: 420   DADSTSVETMYSVASQCLHEKKNKRPDNKKKVQQ  453

         **************************98764444

Domain Sequence
(FASTA)

GNKMGEGGFG VVYKGYVNNT TVAVKKLAAM VDITTEELKQ QFDQEIKVMA KIHERSIVEI 60

RMYSNYGDDV CFQTLLVPYL HLISLLDCRD GTPPLSWHMR CKIAQGAANG INFLHENHHI 120

HRDIKSANIL LDEAFTAKIS DFGLARASEK FAQTVMTSRI VGTTAYMAPE ALRGEITPKS 180

DIYSFGVVLL EIITGLPAVD EHREPQLLLD IKEEIEDEEK TIEDYIDKKM NDADSTSVET 240

MYSVASQCLH EKKNKRPDNK KKVQQ 265

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona intestinalis"; ?>Danio rerio"; ?>Dasypus novemcinctus"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>