EPS-GOG-00031

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-GOG-00031

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPM/PP2C	193.4	7.8E-57	61	375	315

Status

Unreviewed

Ensembl Protein

ENSGGOP00000020235

UniProt Accession

G3RWQ1;

Protein Name

Protein Synonyms/Alias

Gene Name

PPM1D

Gene Synonyms/Alias

PPM1D;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSGGOG00000009046	ENSGGOP00000008841	ENSGGOT00000009081
ENSGGOG00000009046	ENSGGOP00000020235	ENSGGOT00000028141

Organism

Gorilla gorilla

Functional Description

Protein Length

607

Protein Sequence
(FASTA)

MAGLYSLGVS VFSDQGGRKY MEDVTQIVVE PEPTAEEKPS PRRSLSQPLP PRPSPAALPG 60

GEVSGNGPAV AAREARDPLP DAGASPAPSR CCRRRSSVAF FAVCDGHGGR EAAQFAREHL 120

WGFIKKQKGF TSSEPAKVCA AIRKGFLACH LAMWKKLGDW QGRGTGVLAQ SSCSTTRNIF 180

FIKRKKKMIS HVFKDAIVFS SKRNLGSSFI RVLLFNQNLN TSLPKERGKI KRVGGCVMNK 240

SGVNRVVWKR PRLTHNGPVR RSTVIDQIPF LAVARALGDL WSYDFFSGEF VVSPEPDTSV 300

HTLDPQKHKY IILGSDGLWN MIPPQDAISM CQDQEEKKYL MGEHGQSCAK MLVNRALGRW 360

RQRMLRADNT SAIVICISPE VDNQGNFTNE DELYLNLTDS PSYNSQETCV MTPSPCSTPP 420

VKSLEEDPWP RLNSKDHIPA LVRSNAFSEN FLEVSAEITR ENVQGVVIPS KDPEPLEENC 480

AKALTLRIHD SLNNSLPIGL VPTNSTNTVM DQKNLKMSTP GQMKAQEIER TPPTNFKRTL 540

EESNSGPLMK KHRRNGLSRS SGAQPASLPT TSQRKNSVKL TMRRRLRGQK KIGNPLLHQH 600

RKTVCVC 607

Nucleotide Sequence
(FASTA)

ATGGCGGGGC TGTACTCGCT GGGAGTGAGC GTCTTCTCCG ACCAGGGCGG GAGGAAGTAC 60

ATGGAGGACG TTACTCAAAT CGTTGTGGAG CCCGAACCGA CGGCTGAAGA AAAGCCCTCG 120

CCGCGGCGGT CGCTCTCTCA GCCGTTGCCT CCGCGGCCGT CGCCGGCCGC CCTTCCCGGC 180

GGCGAAGTCT CGGGGAACGG CCCAGCGGTG GCAGCCCGAG AGGCTCGCGA CCCTCTGCCG 240

GACGCCGGGG CCTCGCCGGC ACCCAGCCGC TGCTGCCGCC GCCGTTCCTC CGTGGCCTTT 300

TTCGCCGTGT GCGACGGGCA CGGCGGGCGG GAGGCGGCAC AGTTTGCCCG GGAGCACTTG 360

TGGGGTTTCA TCAAGAAGCA GAAGGGTTTC ACCTCGTCCG AGCCGGCTAA GGTTTGCGCT 420

GCCATCCGCA AAGGCTTTCT CGCTTGTCAC CTCGCCATGT GGAAGAAACT GGGAGACTGG 480

CAGGGGCGGG GGACGGGTGT GCTTGCCCAA AGTAGCTGCT CAACAACTAG GAATATATTC 540

TTTATTAAAA GAAAAAAAAA AATGATATCT CATGTTTTTA AAGATGCTAT TGTGTTCTCT 600

TCTAAGAGGA ATCTAGGTAG CAGTTTCATC AGGGTCTTGC TTTTCAATCA GAATCTCAAC 660

ACCTCCCTCC CCAAAGAAAG AGGAAAGATA AAAAGGGTGG GGGGATGTGT AATGAACAAG 720

TCTGGGGTGA ATCGTGTAGT TTGGAAACGA CCTCGACTCA CTCACAATGG ACCTGTTAGA 780

AGGAGCACAG TTATTGACCA GATTCCTTTT CTGGCAGTAG CAAGAGCACT TGGTGATTTG 840

TGGAGCTATG ATTTCTTCAG TGGTGAATTT GTGGTGTCAC CTGAACCAGA CACAAGTGTC 900

CACACTCTTG ACCCTCAGAA GCACAAGTAT ATTATATTGG GGAGTGATGG ACTTTGGAAT 960

ATGATTCCAC CACAAGATGC CATCTCAATG TGCCAGGACC AAGAGGAGAA AAAATACCTG 1020

ATGGGTGAGC ATGGACAATC TTGTGCCAAA ATGCTTGTGA ATCGAGCATT GGGCCGCTGG 1080

AGGCAGCGTA TGCTCCGAGC AGATAACACT AGTGCCATAG TAATCTGCAT CTCTCCAGAA 1140

GTGGACAATC AGGGAAACTT TACCAATGAA GATGAGTTAT ACCTGAACCT GACTGACAGC 1200

CCTTCCTATA ATAGTCAAGA AACCTGTGTG ATGACTCCTT CCCCATGTTC TACACCACCA 1260

GTCAAGTCAC TGGAGGAGGA TCCATGGCCA AGGCTGAATT CTAAGGACCA TATACCTGCC 1320

CTGGTCCGTA GCAATGCCTT CTCAGAGAAT TTTTTAGAGG TTTCAGCTGA GATAACTCGA 1380

GAGAATGTCC AAGGTGTAGT CATACCCTCA AAAGATCCAG AACCACTTGA AGAAAATTGC 1440

GCTAAAGCCC TGACTTTAAG GATACATGAT TCTTTGAATA ATAGCCTTCC AATTGGCCTT 1500

GTGCCTACTA ATTCAACAAA CACTGTCATG GACCAAAAAA ATTTGAAGAT GTCAACTCCT 1560

GGCCAAATGA AAGCCCAAGA AATTGAAAGA ACCCCTCCAA CAAACTTTAA AAGGACATTA 1620

GAAGAGTCCA ATTCTGGCCC CCTGATGAAG AAGCATAGAC GAAATGGCTT AAGTCGAAGT 1680

AGTGGTGCTC AGCCTGCAAG TCTCCCCACA ACCTCACAGC GAAAGAACTC TGTTAAACTC 1740

ACCATGCGAC GCAGACTTAG GGGCCAGAAG AAAATTGGAA ATCCTTTACT TCATCAACAC 1800

AGGAAAACTG TTTGTGTTTG CTGA 1824

Domain Profile

S: 4     gvvsvngrrnemedavtsspnflkspekkdr......laffgvyDGhggsevakfcsekl  57

         g vs+ng+    ++a+++ p++++sp+ +++      +aff+v+DGhgg+e+a+f++e+l

Q: 61    GEVSGNGPAVAAREARDPLPDAGASPAPSRCcrrrssVAFFAVCDGHGGREAAQFAREHL  120

         6799*************************99*****************************

S: 58    heilaeelesseseerkvkkalakaFlstdeel.......kvleeksldidksGstavva  110

         + ++++++ +++se +kv++a++k+Fl+++ ++       +   +  l+++++ +t  +

Q: 121   WGFIKKQKGFTSSEPAKVCAAIRKGFLACHLAMwkklgdwQGRGTGVLAQSSCSTTRNIF  180

         *********************************888775544444455666688888899

S: 111   likdsklyvanvGdSravLcrngk.......avelssdHkpsredEleRieeaggsvilk  163

          ik +k ++++v +  +v++ +++       ++   +  ++s ++E+ +i++ gg v++k

Q: 181   FIKRKKKMISHVFKDAIVFSSKRNlgssfirVLLFNQNLNTSLPKERGKIKRVGGCVMNK  240

         99999****************99989999998999*************************

S: 164   dga.Rv.....................lGvLavsRalGdlylk......pyvtpePevts  195

         +g+ Rv                     +++Lav+RalGdl+++      ++v+peP++++

Q: 241   SGVnRVvwkrprlthngpvrrstvidqIPFLAVARALGDLWSYdffsgeFVVSPEPDTSV  300

         ************************************************************

S: 196   hrltsede.fliLasDGlwdvvsneeavslvrdvle....kkeaeqeaakkLvklalarg  250

         h+l+++++ ++iL+sDGlw+++++++a+s+++d++e    ++e+ q++ak+Lv++al r+

Q: 301   HTLDPQKHkYIILGSDGLWNMIPPQDAISMCQDQEEkkylMGEHGQSCAKMLVNRALGRW  360

         ************************************************************

S: 251   sk.....dnvsaivv  260

         ++     dn+saiv+

Q: 361   RQrmlraDNTSAIVI  375

         *************97

Domain Sequence
(FASTA)

GEVSGNGPAV AAREARDPLP DAGASPAPSR CCRRRSSVAF FAVCDGHGGR EAAQFAREHL 60

WGFIKKQKGF TSSEPAKVCA AIRKGFLACH LAMWKKLGDW QGRGTGVLAQ SSCSTTRNIF 120

FIKRKKKMIS HVFKDAIVFS SKRNLGSSFI RVLLFNQNLN TSLPKERGKI KRVGGCVMNK 180

SGVNRVVWKR PRLTHNGPVR RSTVIDQIPF LAVARALGDL WSYDFFSGEF VVSPEPDTSV 240

HTLDPQKHKY IILGSDGLWN MIPPQDAISM CQDQEEKKYL MGEHGQSCAK MLVNRALGRW 300

RQRMLRADNT SAIVI 315

Keyword

Complete proteome; Hydrolase; Magnesium; Metal-binding; Protein phosphatase; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>