EKS-GOG-00093

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-GOG-00093

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Atypical/PIKK	419.2	1.6E-125	2635	2953	319

Status

Unreviewed

Ensembl Protein

ENSGGOP00000010144

UniProt Accession

G3SBE3;

Protein Name

Protein Synonyms/Alias

Gene Name

ATM

Gene Synonyms/Alias

ATM;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSGGOG00000010362	ENSGGOP00000025419	ENSGGOT00000026093
ENSGGOG00000010362	ENSGGOP00000010144	ENSGGOT00000010440

Organism

Gorilla gorilla

Functional Description

Protein Length

2995

Protein Sequence
(FASTA)

MSLVLNDLLI CCRQLEHDRA TERKKEVEKF KRLIRDPETI KHLDRHSDSK QGKYLNWDAV 60

FRFLQKYIQK ETECLRIAKP NVSASTQASR QKKMQEISSL VKYFIKCANR RAPRLKCQEL 120

LNYIMDTVKD SSNGAIYGAD CSNILLKDIL SVRKYWCEIS QQQWLELFSV YFRLYLKPSQ 180

DVHRVLVARI IHAVTKGCCS QTDGLNSKFL DFFSKAIQCA RQEKSSSGLN HILAALTIFL 240

KTLAVNFRIR VCELGDEILP TLLYIWTQHR LNDSLKEVII ELFQLQIYIH HPKGAKTQEK 300

GAYESTKWKS ILYNLYDLLV NEISHIGSRG KYSSGFRNIA VKENLIELMA DICHQVFNED 360

TRSLEISQSY TTTQRESSDY SVPCKRKKIE LGWEVIKDHL QKSQNDFDLV PWLQIATQLI 420

SKYPASLPNC ELSPLLMILS QLLPQQRHGE RTPYVLRCLT EVALCQDKRS NLESSQKSDL 480

LKLWNKIWCI TFRGISSEQI QAENFGLLGA IIQGSLVEID REFWKLFTGS ACRPSCPAVC 540

CLTLALTTSI VPGTVKMGIE QNMCEVNRSF SLKESIMKWL LFYQLEGDLE NSTEVPPILH 600

SNFPHLVLEK ILVSLTMKNC KAAMNFFQSV PECEHHQKDK EELSFSEVEE LFLQTTFDKM 660

DFLTIVRECG IEKHQSSIGF SVHQNLKESL DRCLLGLSEQ LLNNYSSEIT NSETLVRCSR 720

LLVGVLGCYC YMGVIAEEEA YKSELFQKAK SLMQCAGESI TLFKNKTNEE FRIGSLRNMM 780

QLCTRCLSNC TKKSPNKIAS GFFLRLLTSK LMNDIADICK SLASLIKKPF DRGEVESMED 840

DTNGNLMEVE DQSSVNLFND YPDSSVSDAN EPGESQSTIG AINPLAEEYL SKQDLLFLDM 900

LKFLCLCVTT AQTNTVSFRA ADIRRKLLML IDSSTLDPTK SLHLHMYLLL LKELPGEEYP 960

LPMEDVVELL KPLSNVCSLY RRDQDVCKTI LNHVLHIVKN LGQSNMDSEN TRDAQGQFLT 1020

VIGAFWHLTK ERKYIFSVRM ALVNCLKTLL EADPYSKWAI LNVMGKDFPV NEVFTQFLAD 1080

NHHQVRMLAA ESINRLFQDT KGDSSRLLKA LPLKLQQTAF ENAYLKAQEG MREMSHSAEN 1140

PEPLDEIYNR KSVLLTLIAV VLSCSPICEK QALFALCKSV KENGLEPHLV KKVLEKVSET 1200

FGYRRLEDFM ASHLDYLVLE WLNLQDTEYN LSSFPFILLN YTNIEDFYRS CYKVLIPHLV 1260

IRSHFDEVKS IANQIQEDWK SLLTDCFPKI LVNILPYFAY EGTGDSGMAQ QRETATKVYD 1320

MLKSENLLGK QIDHLFISNL PEIVVELLMT LHEPANSTSQ RTDLCDFSGD LDPAPNPPHF 1380

PSHVIKATFA YISNCHKTKL KSILEILSKS PDSYQKILLA ICEQAAETNN VYKKHRILKI 1440

YHLFVGLLLK DIKSGLGGAW AFVLRDVIYT LIHYINQRPS CIMDVSLRSF SLCCDLLSQV 1500

CQTAVTYCKD ALENHLHVIV GTLIPLVYEQ VEVQKQVLDL LKYLVIDNKD NENLYLTIKL 1560

LDPFPDHVVF KDLRITQQKI KYSRGPFSLL EEINHFLSVS VYDALPLTRL EGLKDLRRQL 1620

ELHKDQMVDI MRASQDNPQD GIMVKLVVNL LQLSKMAINH TGEKEVLEAV GSCLGEVGPI 1680

DFSTIAIQHS KDASYTKALK LFEDKELQWT FIMLTYLNNT LVEDCVKVRS AAVTCLKNIL 1740

ATKTGHSFWE IYKMTTDPML AYLQPFRTSR KKFLEVPRFD KENPFEGLDD INLWIPLSEN 1800

HDIWIKTLTC AFLDSGGTKC EILQLLKPMC EVKTDFCQTV LPYLIHDILL QDTNESWRNL 1860

LSTHVQGFFT SCLRHFLQTS RSTTPANLDS ESEHFFRCCL DKKSQRTMLA VVDYMRRQKR 1920

PSSGTIFNDA FWLDLNYLEV AKVAQSCAAH FTALLYAEIY ADKKSMDDQE KRSLAFEEGS 1980

QSTTISSLSE KSKEETGISL QDLLLEIYRS IGEPDSLYGC GGGKMLQPIT RLRTYEHEAM 2040

WGKALVTYDL ETAIPSSTRQ AGIIQKEVEG TSYHESLYNA LQSLRDREFS TFYEGLKYAR 2100

VKEVEELCKR SLESVYSLYP TLSRLQAIGE LESIGELFSR SVTHRQLSEV YIKWQKHSQL 2160

LKDSDFSFQE PIMALRTVIL EILMEKEMDN SQRECIKDIL TKHLVELSIL ARTFKNTQLP 2220

ERAIFQIKQY NSVSCGVSEW QLEEAQVFWA KKEQSLALSI LKQMIKKLDA SCAANNPSLK 2280

LTYTECLRVC GNWLAETCLE NPAVIMQTYL EKAVEVAGNY DGESSDELRN GKMKAFLSLA 2340

RFSDTQYQRI ENYMKSSEFE NKQALLKRAK EEVGLLREHK IQTNRYTVKV QRELELDELA 2400

LRALKEDRKR FLCKAVENYI NCLLSGEEHD MWVFRLCSLW LENSGVSEVN GMMKRDGMKI 2460

PTYKFLPLMY QLAARMGTKM MGGLGFHEVL NNLISRISMD HPHHTLFIIL ALANANRDEF 2520

LTKPEVARRS RITKNDRTEA ANRIICTIRS RRPQMVRSVE ALCDAYIILA NLDATQWKTQ 2580

RKGINIPADQ PITKLKNLED VVVPTMEIKV DHTGEYGNLV TIQSFKAEFR LAGGVNLPKI 2640

IDCVGSDGKE RRQLVKGRDD LRQDAVMQQV FQMCNTLLQR NTETRKRKLT ICTYKVVPLS 2700

QRSGVLEWCT GTVPIGEFLV NNEDGAHKRY RPNDFSAFQC QKKMMEVQKK SFEEKYEVFM 2760

EVCQNFQPVF RYFCMEKFLD PAIWFEKRLA YTRSVATSSI VGYILGLGDR HVQNILINEQ 2820

SAELVHIDLG VAFEQGKILP TPETVPFRLT RDIVDGMGIT GVEGVFRRCC EKTMEVMRNS 2880

QETLLTIVEV LLYDPLFDWT MNPLKALYLQ QRPEDETELH PTLNADDQEC KRNLSDIDQS 2940

FNKVAERVLM RLQEKLKGVE EGTVLSVGGQ VNLLIQQAID PKNLSRLFPG WKAWV 2995

Nucleotide Sequence
(FASTA)

ATGAGTCTAG TACTTAATGA TCTGCTTATC TGCTGCCGTC AACTAGAACA TGATAGAGCT 60

ACAGAACGAA AGAAAGAAGT TGAGAAATTT AAGCGCCTGA TTCGAGATCC TGAAACAATT 120

AAACATCTAG ATCGGCATTC AGATTCCAAA CAAGGAAAAT ATTTGAATTG GGATGCTGTT 180

TTTAGATTTT TACAGAAATA TATTCAGAAA GAAACAGAAT GTCTGAGAAT AGCAAAACCA 240

AACGTATCAG CCTCAACACA AGCCTCCAGG CAGAAAAAGA TGCAGGAAAT CAGTAGTTTG 300

GTCAAATACT TCATCAAATG TGCAAACAGA AGAGCACCTA GGCTAAAATG TCAAGAACTC 360

TTAAATTATA TCATGGATAC AGTGAAAGAT TCATCTAATG GTGCTATTTA CGGAGCTGAT 420

TGTAGCAACA TACTACTGAA AGACATTCTT TCTGTGAGAA AATACTGGTG TGAAATATCT 480

CAGCAACAGT GGTTAGAATT GTTCTCTGTG TACTTCAGGC TCTATCTGAA ACCTTCACAA 540

GATGTTCATA GAGTTTTAGT GGCTAGAATA ATTCATGCTG TTACCAAAGG ATGCTGTTCT 600

CAGACTGACG GATTAAATTC CAAATTTTTG GACTTTTTTT CCAAGGCTAT TCAGTGTGCA 660

AGACAAGAAA AGAGCTCTTC AGGTCTAAAT CATATCTTAG CAGCTCTTAC TATCTTCCTC 720

AAGACTTTGG CTGTCAACTT TCGAATTCGA GTGTGTGAAT TAGGAGATGA AATTCTTCCC 780

ACTTTGCTTT ATATTTGGAC TCAACATAGA CTTAATGATT CTTTAAAAGA AGTCATTATT 840

GAATTATTTC AACTGCAAAT TTATATCCAT CATCCAAAAG GAGCCAAAAC CCAAGAAAAA 900

GGTGCTTATG AATCAACAAA ATGGAAAAGT ATTTTATACA ACTTATATGA TCTGCTAGTG 960

AATGAGATAA GTCATATAGG AAGTAGAGGA AAGTATTCTT CAGGATTTCG TAATATTGCC 1020

GTCAAAGAAA ATTTGATTGA ATTGATGGCA GATATCTGTC ACCAGGTTTT TAATGAAGAT 1080

ACCAGATCCT TGGAGATTTC TCAATCTTAT ACTACTACAC AAAGAGAATC TAGTGATTAC 1140

AGTGTACCTT GCAAAAGGAA GAAAATAGAA CTAGGCTGGG AAGTAATAAA AGATCACCTT 1200

CAGAAGTCAC AGAATGATTT TGATCTTGTG CCTTGGCTAC AGATTGCAAC CCAATTAATA 1260

TCAAAGTATC CTGCAAGTTT ACCTAACTGT GAGCTGTCTC CATTACTGAT GATACTATCT 1320

CAGCTTCTAC CCCAACAGCG ACATGGGGAA CGTACACCAT ATGTGTTACG ATGCCTTACG 1380

GAAGTTGCAT TGTGTCAAGA CAAGAGGTCA AACCTAGAAA GCTCACAAAA GTCAGATTTA 1440

TTAAAACTCT GGAATAAAAT TTGGTGTATT ACCTTTCGTG GTATAAGTTC TGAGCAAATA 1500

CAAGCTGAAA ACTTTGGCTT ACTTGGAGCC ATAATTCAGG GTAGTTTAGT TGAGATTGAC 1560

AGAGAATTCT GGAAGTTATT TACTGGGTCA GCCTGCAGAC CTTCCTGTCC TGCAGTATGC 1620

TGTTTGACTT TGGCACTGAC CACCAGTATA GTTCCAGGAA CGGTAAAAAT GGGAATAGAG 1680

CAAAATATGT GTGAAGTAAA TAGAAGCTTT TCTTTAAAGG AATCAATAAT GAAATGGCTC 1740

TTATTCTATC AGTTAGAGGG TGACTTAGAA AACAGCACAG AAGTGCCTCC TATTCTTCAC 1800

AGTAATTTTC CTCATCTTGT ACTGGAGAAA ATTCTTGTGA GTCTCACTAT GAAAAACTGT 1860

AAAGCTGCAA TGAATTTTTT CCAAAGCGTG CCAGAATGTG AACACCACCA AAAAGATAAA 1920

GAAGAACTTT CATTCTCAGA AGTAGAAGAA CTATTTCTTC AGACAACTTT TGACAAGATG 1980

GACTTTTTAA CCATTGTGAG AGAATGTGGT ATAGAAAAGC ACCAGTCCAG TATTGGCTTC 2040

TCTGTCCACC AGAATCTCAA GGAATCACTG GATCGCTGTC TTCTGGGATT ATCAGAACAG 2100

CTTCTGAATA ATTACTCATC TGAGATTACA AATTCAGAAA CTCTTGTCCG GTGTTCACGT 2160

CTTTTGGTGG GTGTCCTTGG CTGCTACTGT TATATGGGTG TAATAGCTGA AGAGGAAGCA 2220

TATAAGTCAG AATTATTCCA GAAAGCCAAG TCTCTAATGC AATGTGCAGG AGAAAGTATC 2280

ACTCTGTTTA AAAATAAGAC AAATGAGGAA TTCAGAATTG GTTCCTTGAG AAATATGATG 2340

CAGCTATGTA CACGTTGCTT GAGCAACTGT ACCAAGAAGA GTCCAAATAA GATTGCATCT 2400

GGCTTTTTCC TACGATTGTT AACATCAAAG CTAATGAATG ACATTGCAGA TATTTGTAAA 2460

AGTTTAGCAT CCTTAATCAA AAAGCCATTT GACCGTGGAG AAGTAGAATC AATGGAAGAT 2520

GATACTAATG GAAATCTAAT GGAGGTGGAG GATCAGTCAT CCGTGAATCT ATTTAACGAT 2580

TACCCTGATA GTAGTGTTAG TGATGCAAAC GAACCTGGAG AGAGCCAAAG TACCATAGGT 2640

GCCATTAATC CTTTAGCTGA AGAATATCTG TCAAAGCAAG ATCTACTTTT CTTAGACATG 2700

CTCAAGTTCT TGTGTTTGTG TGTAACTACT GCTCAGACCA ATACTGTGTC CTTTAGGGCA 2760

GCTGATATTC GGAGGAAATT GTTAATGTTA ATTGATTCTA GCACGCTAGA CCCTACCAAA 2820

TCCCTCCACC TGCATATGTA TCTACTGCTT TTAAAGGAGC TTCCTGGAGA AGAGTACCCC 2880

TTGCCAATGG AAGATGTTGT TGAACTTCTG AAACCACTAT CCAATGTGTG TTCTTTGTAT 2940

CGTCGTGACC AAGATGTTTG TAAAACTATT TTAAACCATG TCCTTCATAT AGTGAAAAAC 3000

CTAGGTCAAA GCAATATGGA CTCTGAGAAC ACAAGGGATG CTCAGGGACA GTTTCTTACA 3060

GTAATTGGAG CATTTTGGCA TCTAACAAAG GAGAGGAAAT ATATATTCTC TGTAAGAATG 3120

GCCCTAGTAA ATTGCCTTAA AACTTTGCTT GAGGCTGATC CTTATTCAAA ATGGGCCATT 3180

CTTAATGTAA TGGGAAAAGA CTTTCCTGTA AATGAAGTAT TTACACAATT TCTTGCTGAC 3240

AATCATCACC AAGTTCGCAT GTTGGCTGCA GAGTCAATCA ATAGATTGTT CCAGGACACG 3300

AAGGGAGATT CTTCCAGGTT ACTGAAAGCA CTTCCTTTGA AGCTTCAGCA AACAGCTTTT 3360

GAAAATGCAT ACTTGAAAGC TCAGGAAGGA ATGAGAGAAA TGTCCCATAG TGCTGAGAAC 3420

CCTGAACCTT TGGATGAAAT TTATAATAGA AAATCTGTTT TACTGACGTT GATAGCTGTG 3480

GTTTTATCCT GTAGCCCTAT CTGCGAAAAA CAGGCTTTGT TTGCCCTGTG TAAATCTGTG 3540

AAAGAGAATG GATTAGAACC TCACCTTGTG AAAAAGGTTT TAGAGAAAGT TTCTGAAACT 3600

TTTGGATATA GACGTTTAGA AGACTTTATG GCATCTCATT TAGATTATCT GGTTTTGGAA 3660

TGGCTAAATC TTCAAGATAC TGAATACAAC TTATCTTCTT TTCCTTTTAT TTTATTAAAC 3720

TACACAAATA TTGAGGATTT CTATAGATCT TGTTATAAGG TTTTGATTCC ACATCTGGTG 3780

ATTAGAAGTC ATTTTGATGA GGTGAAGTCC ATTGCTAATC AGATTCAAGA GGACTGGAAA 3840

AGTCTTCTAA CAGACTGCTT TCCAAAGATT CTTGTAAATA TTCTTCCTTA TTTTGCCTAT 3900

GAGGGTACAG GAGACAGCGG GATGGCACAG CAAAGAGAGA CTGCTACCAA GGTCTATGAT 3960

ATGCTTAAAA GTGAAAACTT ATTGGGAAAA CAGATTGATC ACTTATTCAT TAGTAATTTA 4020

CCAGAGATTG TGGTGGAGTT ATTGATGACG TTACATGAGC CAGCAAATTC TACCAGTCAG 4080

AGGACTGACC TCTGTGACTT TTCAGGGGAT TTGGATCCTG CTCCTAATCC ACCTCATTTT 4140

CCATCGCATG TGATTAAAGC AACATTTGCC TATATCAGCA ATTGTCATAA AACCAAGTTA 4200

AAAAGCATTT TAGAAATTCT TTCCAAAAGC CCTGATTCCT ATCAGAAAAT TCTTCTTGCC 4260

ATATGTGAGC AAGCAGCTGA AACAAATAAT GTTTATAAGA AACACAGAAT TCTTAAAATA 4320

TACCACCTGT TTGTTGGTTT ATTACTGAAA GATATAAAAA GTGGCTTAGG AGGAGCTTGG 4380

GCCTTTGTTC TTCGAGATGT TATTTATACT TTGATTCACT ATATCAACCA AAGGCCTTCT 4440

TGTATCATGG ATGTGTCATT ACGTAGCTTC TCCCTTTGTT GTGACTTATT AAGTCAGGTT 4500

TGCCAGACAG CCGTGACTTA CTGTAAGGAT GCTCTAGAAA ACCATCTTCA TGTTATTGTT 4560

GGTACACTTA TACCCCTTGT GTATGAGCAG GTGGAGGTTC AGAAACAGGT ATTGGACTTG 4620

TTGAAATACT TAGTGATAGA TAACAAGGAT AATGAAAACC TCTATCTCAC GATTAAGCTT 4680

TTAGATCCTT TTCCTGACCA TGTTGTTTTT AAGGATTTGC GTATTACTCA GCAAAAAATC 4740

AAATACAGTA GAGGACCCTT TTCACTCTTG GAGGAAATTA ACCATTTTCT CTCAGTAAGT 4800

GTTTATGATG CACTTCCATT GACAAGACTT GAAGGACTAA AGGATCTTCG AAGACAACTG 4860

GAACTACATA AGGATCAGAT GGTGGACATT ATGAGAGCTT CTCAGGATAA TCCACAAGAT 4920

GGGATTATGG TGAAACTAGT TGTCAATTTG TTGCAGTTAT CCAAGATGGC AATAAACCAC 4980

ACTGGTGAAA AAGAAGTTCT AGAGGCTGTT GGAAGCTGCT TGGGAGAAGT GGGTCCTATA 5040

GATTTCTCTA CCATAGCTAT ACAACATAGT AAAGATGCAT CTTATACCAA GGCCCTTAAG 5100

TTATTTGAAG ATAAAGAACT TCAGTGGACC TTCATAATGC TGACCTACCT GAATAACACA 5160

CTGGTAGAAG ATTGTGTCAA AGTTCGATCA GCAGCTGTTA CCTGTTTGAA AAACATTTTA 5220

GCCACAAAGA CTGGACATAG TTTCTGGGAG ATTTATAAGA TGACAACAGA TCCAATGCTG 5280

GCCTATCTAC AGCCTTTTAG AACATCAAGA AAAAAGTTTT TAGAAGTACC CAGATTTGAC 5340

AAAGAAAACC CTTTTGAAGG CCTGGATGAT ATAAATCTGT GGATTCCTCT AAGTGAAAAT 5400

CATGACATTT GGATAAAGAC ACTGACTTGT GCTTTTTTGG ACAGTGGAGG CACAAAATGT 5460

GAAATTCTTC AATTATTAAA GCCAATGTGT GAAGTGAAAA CTGACTTTTG TCAGACTGTA 5520

CTTCCATACT TGATTCATGA TATTTTACTC CAAGATACAA ATGAATCATG GAGAAATCTG 5580

CTTTCTACAC ATGTTCAGGG ATTTTTCACC AGCTGTCTTC GACACTTCTT GCAAACGAGC 5640

CGATCCACAA CCCCTGCAAA CTTGGATTCA GAGTCAGAGC ACTTTTTCCG ATGCTGTTTG 5700

GATAAAAAAT CACAAAGAAC AATGCTTGCT GTTGTGGACT ACATGAGAAG ACAAAAGAGA 5760

CCTTCTTCAG GAACAATTTT TAATGATGCT TTCTGGCTGG ATTTAAATTA TCTAGAAGTT 5820

GCCAAGGTAG CTCAGTCTTG TGCTGCTCAC TTTACAGCTT TACTCTATGC AGAAATCTAT 5880

GCAGATAAGA AAAGCATGGA TGATCAAGAG AAAAGAAGTC TTGCATTTGA AGAAGGAAGC 5940

CAGAGTACTA CTATTTCTAG CTTGAGTGAA AAAAGTAAAG AAGAAACTGG AATAAGTTTA 6000

CAGGATCTTC TCTTAGAAAT CTACAGAAGT ATAGGGGAGC CAGATAGTTT GTATGGCTGT 6060

GGTGGAGGGA AGATGTTACA ACCCATTACT AGACTACGAA CATATGAACA CGAAGCAATG 6120

TGGGGCAAAG CCCTAGTAAC ATATGACCTC GAAACAGCAA TCCCCTCATC AACACGCCAG 6180

GCAGGAATCA TTCAGAAAGA AGTAGAAGGA ACCAGTTACC ATGAATCATT GTACAATGCT 6240

CTACAATCTC TAAGAGACAG AGAATTCTCT ACATTTTATG AAGGTCTCAA ATATGCCAGA 6300

GTAAAAGAAG TAGAAGAGTT GTGTAAGCGC AGTCTTGAGT CTGTGTATTC GCTCTATCCC 6360

ACACTTAGCA GGTTGCAGGC CATTGGAGAG CTGGAAAGCA TTGGGGAGCT TTTCTCAAGA 6420

TCAGTCACAC ATAGACAACT CTCTGAAGTA TATATTAAGT GGCAGAAACA CTCCCAGCTT 6480

CTCAAGGACA GTGATTTTAG TTTTCAGGAG CCTATCATGG CTCTACGCAC AGTCATTTTG 6540

GAGATCCTGA TGGAAAAGGA AATGGACAAC TCACAAAGAG AATGTATTAA GGACATTCTC 6600

ACCAAACACC TTGTAGAACT CTCTATACTG GCCAGAACTT TCAAGAACAC TCAGCTCCCT 6660

GAAAGGGCAA TATTTCAAAT TAAACAGTAC AATTCAGTTA GCTGTGGAGT CTCTGAGTGG 6720

CAGCTGGAAG AAGCACAAGT ATTCTGGGCA AAAAAGGAGC AGAGTCTTGC CCTGAGTATT 6780

CTCAAGCAAA TGATCAAGAA ATTGGATGCC AGCTGTGCAG CGAACAATCC CAGCCTAAAA 6840

CTTACATACA CAGAATGTCT GAGGGTTTGT GGCAACTGGT TAGCAGAAAC GTGCTTAGAA 6900

AATCCTGCGG TCATCATGCA GACCTATCTA GAAAAGGCAG TAGAAGTTGC TGGAAATTAT 6960

GATGGAGAAA GCAGTGATGA GCTAAGAAAT GGAAAAATGA AGGCATTTCT CTCATTAGCC 7020

CGGTTTTCAG ATACTCAATA CCAAAGAATT GAAAACTACA TGAAATCATC GGAATTTGAA 7080

AACAAGCAAG CTCTCCTGAA AAGAGCCAAA GAGGAAGTAG GTCTCCTTAG GGAACATAAA 7140

ATTCAGACAA ACAGATACAC AGTAAAGGTT CAGCGGGAGC TGGAGTTGGA TGAATTAGCC 7200

CTGCGTGCAC TTAAAGAGGA TCGTAAACGC TTCTTATGTA AAGCAGTTGA AAATTATATC 7260

AACTGCTTAT TAAGTGGAGA AGAGCATGAT ATGTGGGTAT TCCGACTTTG TTCCCTCTGG 7320

CTTGAAAATT CTGGAGTTTC TGAAGTCAAT GGCATGATGA AGAGAGACGG AATGAAGATT 7380

CCAACATATA AATTTTTGCC TCTTATGTAC CAATTGGCTG CTAGAATGGG GACCAAGATG 7440

ATGGGAGGCC TAGGATTTCA TGAAGTCCTC AATAATCTAA TCTCTAGAAT TTCAATGGAT 7500

CACCCCCATC ATACTTTGTT TATTATACTG GCCTTAGCAA ATGCAAACAG AGATGAATTT 7560

CTGACTAAAC CAGAGGTAGC CAGAAGAAGC AGAATAACTA AAAATGATCG AACAGAGGCT 7620

GCAAATAGAA TAATATGTAC TATCAGAAGT AGGAGACCTC AGATGGTCAG AAGTGTTGAG 7680

GCACTTTGTG ATGCTTATAT TATATTAGCA AACTTAGATG CCACTCAGTG GAAGACTCAG 7740

AGAAAAGGCA TAAATATTCC AGCAGACCAG CCAATTACTA AACTTAAGAA TTTAGAAGAT 7800

GTTGTTGTCC CTACTATGGA AATTAAGGTG GACCACACAG GAGAATATGG AAATCTGGTG 7860

ACTATACAGT CATTTAAAGC AGAATTTCGC TTAGCAGGAG GTGTAAATTT ACCAAAAATA 7920

ATAGATTGTG TAGGTTCCGA TGGCAAGGAG AGGAGACAGC TTGTTAAGGG CCGTGATGAC 7980

CTGAGACAAG ATGCTGTCAT GCAACAGGTC TTCCAGATGT GTAATACATT ACTGCAGAGA 8040

AACACGGAAA CTAGGAAGAG GAAATTAACT ATCTGTACTT ATAAGGTGGT TCCCCTCTCT 8100

CAGCGAAGTG GTGTTCTTGA ATGGTGCACA GGAACTGTCC CCATTGGTGA ATTTCTTGTT 8160

AACAATGAAG ATGGTGCTCA TAAAAGATAC AGGCCAAATG ATTTCAGTGC CTTTCAGTGC 8220

CAAAAGAAAA TGATGGAGGT GCAAAAAAAG TCTTTTGAAG AGAAATATGA AGTCTTCATG 8280

GAGGTTTGCC AAAATTTTCA ACCAGTTTTC CGTTACTTCT GCATGGAAAA ATTCTTGGAT 8340

CCAGCTATTT GGTTTGAGAA GCGATTGGCT TATACACGCA GTGTAGCTAC TTCTTCTATT 8400

GTTGGTTACA TACTTGGACT TGGTGATAGA CATGTACAGA ATATCTTGAT AAATGAGCAG 8460

TCAGCAGAAC TTGTACATAT AGATCTAGGT GTTGCTTTTG AACAGGGCAA AATCCTTCCT 8520

ACTCCTGAGA CAGTTCCTTT TAGACTCACC AGAGATATTG TGGATGGCAT GGGCATTACC 8580

GGTGTTGAAG GTGTCTTCAG AAGATGCTGT GAGAAAACCA TGGAAGTGAT GAGAAACTCT 8640

CAGGAAACTC TGTTAACCAT TGTAGAGGTC CTTCTATATG ATCCACTCTT TGACTGGACC 8700

ATGAATCCTT TGAAAGCTTT GTATTTACAG CAGAGGCCAG AAGATGAAAC TGAGCTTCAC 8760

CCTACTCTGA ATGCAGATGA CCAAGAATGC AAACGAAATC TCAGTGATAT TGACCAGAGT 8820

TTCAACAAAG TAGCTGAACG TGTCTTAATG AGACTACAAG AGAAACTGAA AGGAGTGGAA 8880

GAAGGCACTG TGCTCAGTGT TGGTGGACAA GTGAATTTGC TCATACAGCA GGCCATAGAC 8940

CCCAAAAATC TCAGCCGACT TTTCCCAGGA TGGAAAGCTT GGGTGTGA 8988

Domain Profile

S: 14    kqkpkklllrGsdgkeypyLvkgkeDlrqdervlqlfslvNtlLakdketsrrkLkirty  73

          + pk +   Gsdgke+++Lvkg++Dlrqd++++q+f+++NtlL++++et++rkL+i+ty

Q: 2635  VNLPKIIDCVGSDGKERRQLVKGRDDLRQDAVMQQVFQMCNTLLQRNTETRKRKLTICTY  2694

         567999999***************************************************

S: 74    kVvplstrsgliewventvsLkellkklvekkavlldqpisyrykdlstvqarkpklkhl  133

         kVvpls+rsg++ew+++tv+++e+l   v++++++++   +yr++d+s++q++k++++++

Q: 2695  KVVPLSQRSGVLEWCTGTVPIGEFL---VNNEDGAHK---RYRPNDFSAFQCQKKMMEVQ  2748

         *************************...799*****9...********************

S: 134   kls....levfkevlenlvpkdllkklllekfpspeewfelrkaytrslAvislvgyiLg  189

         k+s    +evf+ev++n++p  +++++++ekf++p+ wfe+r aytrs+A++s+vgyiLg

Q: 2749  KKSfeekYEVFMEVCQNFQP--VFRYFCMEKFLDPAIWFEKRLAYTRSVATSSIVGYILG  2806

         ********************..9*************************************

S: 190   LgdrhlenllidqetgevvhidfgvafekaktqlkvpekvPFRLTrnivnalgvtgveGv  249

         Lgdrh++n+li+++++e+vhid+gvafe++k+ l++pe+vPFRLTr+iv+++g+tgveGv

Q: 2807  LGDRHVQNILINEQSAELVHIDLGVAFEQGKI-LPTPETVPFRLTRDIVDGMGITGVEGV  2865

         ********************************.***************************

S: 250   frasceavlrvlreskeklltiLevflydplvdwkk......kkktsketeeelaekaka  303

         fr++ce++++v+r+s+e+llti+ev+lydpl+dw++      + ++++e+e+el+++ +a

Q: 2866  FRRCCEKTMEVMRNSQETLLTIVEVLLYDPLFDWTMnplkalYLQQRPEDETELHPTLNA  2925

         ******************************************9*****************

S: 304   ealkikkllskvekaenavatrdlllle  331

         +++++k++ls++++++n+va+r+l++l+

Q: 2926  DDQECKRNLSDIDQSFNKVAERVLMRLQ  2953

         ***********************99987

Domain Sequence
(FASTA)

VNLPKIIDCV GSDGKERRQL VKGRDDLRQD AVMQQVFQMC NTLLQRNTET RKRKLTICTY 60

KVVPLSQRSG VLEWCTGTVP IGEFLVNNED GAHKRYRPND FSAFQCQKKM MEVQKKSFEE 120

KYEVFMEVCQ NFQPVFRYFC MEKFLDPAIW FEKRLAYTRS VATSSIVGYI LGLGDRHVQN 180

ILINEQSAEL VHIDLGVAFE QGKILPTPET VPFRLTRDIV DGMGITGVEG VFRRCCEKTM 240

EVMRNSQETL LTIVEVLLYD PLFDWTMNPL KALYLQQRPE DETELHPTLN ADDQECKRNL 300

SDIDQSFNKV AERVLMRLQ 319

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity
GO:0000077	; P:DNA damage checkpoint
GO:0006281	; P:DNA repair
GO:0016572	; P:histone phosphorylation
GO:0090399	; P:replicative senescence
GO:0010212	; P:response to ionizing radiation
GO:0000723	; P:telomere maintenance

KEGG

InterPros

IPR016024	; ARM-type_fold.
IPR015519	; ATM/Tel1.
IPR003152	; FATC.
IPR011009	; Kinase-like_dom.
IPR000403	; PI3/4_kinase_cat_dom.
IPR018936	; PI3/4_kinase_CS.
IPR003151	; PIK-rel_kinase_FAT.
IPR014009	; PIK_FAT.
IPR021668	; TAN.

Pfam

PF02259	; FAT; 1.
PF02260	; FATC; 1.
PF00454	; PI3_PI4_kinase; 1.
PF11640	; TAN; 1.

SMARTs

SM00146

; PI3Kc; 1.

Prosites

PS51189	; FAT; 1.
PS51190	; FATC; 1.
PS00915	; PI3_4_KINASE_1; 1.
PS00916	; PI3_4_KINASE_2; 1.
PS50290	; PI3_4_KINASE_3; 1.

Prints

Created Date

20-Feb-2013