EKS-GOG-00090

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-GOG-00090

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Atypical/PIKK	444.3	3.9E-133	2030	2354	325

Status

Unreviewed

Ensembl Protein

ENSGGOP00000010372

UniProt Accession

G3RPW1;

Protein Name

Protein Synonyms/Alias

Gene Name

MTOR

Gene Synonyms/Alias

MTOR;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSGGOG00000010597	ENSGGOP00000010372	ENSGGOT00000010677
ENSGGOG00000010597	ENSGGOP00000017833	ENSGGOT00000022095

Organism

Gorilla gorilla

Functional Description

Protein Length

2426

Protein Sequence
(FASTA)

MLGTGPAAAT TAATTSSNVS VLQQFASGLK SRNEETRAKA AKELQHYVTM ELREMSQEES 60

TRFYDQLNHH IFELVSSSDA NERKGGILAI VLVLRELAIS VPTFFFQQVQ PFFDNIFVAV 120

WDPKQAIREG AVAALRACLI LTTQREPKEM QKPQWYRRLR EEMEEITQQQ LVHDKYCKDL 180

MGFGTKPRHI TPFTSFQAVQ PQQSNALVGL LGYSSHQGLM GFGASPSPAK STLVESRCCR 240

DLMEEKFDQV CQWVLKCRNS KNSLIQMTIL NLLPRLAAFR PSAFTDTQYL QDTMNHVLSC 300

VKKEKERTAA FQALGLLSVA VRSEFKVYLP RVLDIIRAAL PPKDFAHKRQ KAMQVDATVF 360

TCISMLARAM GPGIQQDIKE LLEPMLAVGL SPALTAVLYD LSRQIPQLKK DIQDGLLKML 420

SLVLMHKPLR HPGMPKGLAH QLASPGLTTL PEASDVGSIT LALRTLGSFE FEGHSLTQFV 480

RHCADHFLNS EHKEIRMEAA RTCSRLLTPS IHLISGHAHV VSQTAVQVVA DVLSKLLVVG 540

ITDPDPDIRY CVLASLDERF DAHLAQAENL QALFVALNDQ VFEIRELAIC TVGRLSSMNP 600

AFVMPFLRKM LIQILTELEH SGIGRIKEQS ARMLGHLVSN APRLIRPYME PILKALILKL 660

KDPDPDPNPG VINNVLATIG ELAQVSGLEM RKWVDELFII IMDMLQDSSL LAKRQVALWT 720

LGQLVASTGY VVEPYRKYPT LLEVLLNFLK TEQNQGTRRE AIRVLGLLGA LDPYKHKVNI 780

GMIDQSRDAS AVSLSESKSS QDSSDYSTSE MLVNMGNLPL DEFYPAVSMV ALMRIFRDQS 840

LSHHHTMVVQ AITFIFKSLG LKCVQFLPQV MPTFLNVIRV CDGAIREFLF QQLGMLVSFV 900

KSHIRPYMDE IVTLMREFWV MNTSIQSTII LLIEQIVVAL GGEFKLYLPQ LIPHMLRVFM 960

HDNSPGRIVS IKLLAAIQLF GANLDDYLHL LLPPIVKLFD APEAPLPSRK AALETVDRLT 1020

ESLDFTDYAS RIIHPIVRTL DQSPELRSTA MDTLSSLVFQ LGKKYQIFIP MVNKVLVRHR 1080

INHQRYDVLI CRIVKGYTLA DEEEDPLIYQ HRMLRSGQGD ALASGPVETG PMKKLHVSTI 1140

NLQKAWGAAR RVSKDDWLEW LRRLSLELLK DSSSPSLRSC WALAQAYNPM ARDLFNAAFV 1200

SCWSELNEDQ QDELIRSIEL ALTSQDIAEV TQTLLNLAEF MEHSDKGPLP LRDDNGIVLL 1260

GERAAKCRAY AKALHYKELE FQKGPTPAIL ESLISINNKL QQPEAAAGVL EYAMKHFGEL 1320

EIQATWYEKL HEWEDALVAY DKKMDTNKDD PELMLGRMRC LEALGEWGQL HQQCCEKWTL 1380

VNDETQAKMA RMAAAAAWGL GQWDSMEEYT CMIPRDTHDG AFYRAVLALH QDLFSLAQQC 1440

IDKARDLLDA ELTAMAGESY SRAYGAMVSC HMLSELEEVI QYKLVPERRE IIRQIWWERL 1500

QGCQRIVEDW QKILMVRSLV VSPHEDMRTW LKYASLCGKS GRLALAHKTL VLLLGVDPSR 1560

QLDHPLPTVH PQVTYAYMKN MWKSARKIDA FQHMQHFVQT MQQQAQHAIA TEDQQHKQEL 1620

HKLMARCFLK LGEWQLNLQG INESTIPKVL QYYSAATEHD RSWYKAWHAW AVMNFEAVLH 1680

YKHQNQARDE KKKLRHASGA NITNATTAAT TAATATTTAS TEGSNSESEA ESTENSPTPS 1740

PLQKKVTEDL SKTLLMYTVP AVQGFFRSIS LSRGNNLQDT LRVLTLWFDY GHWPDVNEAL 1800

VEGVKAIQID TWLQVIPQLI ARIDTPRPLV GRLIHQLLTD IGRYHPQALI YPLTVASKST 1860

TTARHNAANK ILKNMCEHSN TLVQQAMMVS EELIRVAILW HEMWHEGLEE ASRLYFGERN 1920

VKGMFEVLEP LHAMMERGPQ TLKETSFNQA YGRDLMEAQE WCRKYMKSGN VKDLTQAWDL 1980

YYHVFRRISK QLPQLTSLEL QYVSPKLLMC RDLELAVPGT YDPNQPIIRI QSIAPSLQVI 2040

TSKQRPRKLT LMGSNGHEFV FLLKGHEDLR QDERVMQLFG LVNTLLANDP TSLRKNLSIQ 2100

RYAVIPLSTN SGLIGWVPHC DTLHALIRDY REKKKILLNI EHRIMLRMAP DYDHLTLMQK 2160

VEVFEHAVNN TAGDDLAKLL WLKSPSSEVW FDRRTNYTRS LAVMSMVGYI LGLGDRHPSN 2220

LMLDRLSGKI LHIDFGDCFE VAMTREKFPE KIPFRLTRML TNAMEVTGLD GNYRITCHTV 2280

MEVLREHKDS VMAVLEAFVY DPLLNWRLMD TNTKGNKRSR TRTDSYSAGQ SVEILDGVEL 2340

GEPAHKKTGT TVPESIHSFI GDGLVKPEAL NKKAIQIINR VRDKLTGRDF SHDDTLDVPT 2400

QVELLIKQAT SHENLCQCYI GWCPFW 2426

Nucleotide Sequence
(FASTA)

ATGCTTGGAA CCGGACCTGC CGCCGCCACC ACCGCTGCCA CCACATCTAG CAATGTGAGC 60

GTCCTGCAGC AGTTTGCCAG TGGCCTAAAG AGCCGGAATG AGGAAACCAG GGCCAAAGCC 120

GCCAAGGAGC TCCAGCACTA TGTCACCATG GAACTCCGAG AGATGAGTCA AGAGGAGTCT 180

ACTCGCTTCT ATGACCAACT GAACCATCAC ATTTTTGAAT TGGTTTCCAG CTCAGATGCC 240

AATGAGAGGA AAGGTGGCAT CTTGGCCATA GTCCTGGTTC TCCGTGAGCT GGCCATCAGC 300

GTCCCTACCT TCTTCTTCCA GCAAGTGCAA CCCTTCTTTG ACAACATTTT TGTGGCCGTG 360

TGGGACCCCA AACAGGCCAT CCGTGAGGGA GCTGTAGCCG CCCTTCGTGC CTGTCTGATT 420

CTCACAACCC AGCGTGAGCC GAAGGAGATG CAGAAGCCTC AGTGGTACAG GCGTCTGAGA 480

GAAGAAATGG AAGAAATCAC ACAGCAGCAG CTGGTACACG ACAAGTACTG CAAAGATCTC 540

ATGGGCTTCG GAACAAAACC TCGTCACATT ACCCCCTTCA CCAGTTTCCA GGCTGTACAG 600

CCCCAGCAGT CAAATGCCTT GGTGGGGCTG CTGGGGTACA GCTCTCACCA AGGCCTCATG 660

GGATTTGGGG CCTCCCCCAG TCCAGCTAAG TCTACCCTGG TGGAGAGCCG GTGTTGCAGA 720

GACTTGATGG AGGAGAAATT TGATCAGGTG TGCCAGTGGG TGCTGAAATG CAGGAATAGC 780

AAGAACTCGC TGATCCAAAT GACAATCCTT AATTTGTTGC CCCGCTTGGC TGCATTCCGA 840

CCTTCTGCCT TCACAGATAC CCAGTATCTC CAAGATACCA TGAACCATGT CCTAAGCTGT 900

GTCAAGAAGG AGAAGGAACG TACAGCGGCC TTCCAAGCCC TGGGGCTACT TTCCGTGGCT 960

GTGAGATCTG AGTTTAAGGT CTATTTGCCT CGCGTGCTGG ACATCATCCG AGCGGCCCTG 1020

CCCCCAAAGG ACTTCGCCCA TAAGAGGCAG AAGGCAATGC AGGTGGACGC CACAGTCTTC 1080

ACTTGCATCA GCATGCTGGC TCGAGCAATG GGGCCAGGCA TCCAGCAGGA TATCAAGGAG 1140

CTGCTGGAGC CCATGCTGGC AGTGGGACTA AGCCCTGCCC TCACTGCAGT GCTCTACGAC 1200

CTGAGCCGTC AGATTCCACA GCTAAAGAAG GACATTCAAG ATGGGCTACT GAAAATGCTG 1260

TCCCTGGTCC TTATGCACAA ACCCCTCCGC CACCCAGGCA TGCCCAAGGG CCTGGCCCAT 1320

CAGCTGGCCT CTCCTGGCCT CACGACCCTC CCTGAGGCTA GCGATGTGGG CAGCATCACT 1380

CTTGCCCTCC GAACGCTTGG CAGCTTTGAA TTTGAAGGCC ACTCTCTGAC CCAATTTGTT 1440

CGCCACTGTG CGGATCATTT CCTGAACAGT GAGCACAAGG AGATCCGCAT GGAGGCTGCC 1500

CGCACCTGCT CCCGCCTGCT CACACCCTCC ATCCACCTCA TCAGTGGCCA TGCTCATGTG 1560

GTTAGCCAGA CCGCAGTGCA AGTGGTGGCA GATGTGCTTA GCAAACTGCT CGTAGTTGGG 1620

ATAACAGATC CTGACCCTGA CATTCGCTAT TGTGTCTTGG CGTCCCTGGA CGAGCGCTTT 1680

GATGCACACC TGGCCCAGGC GGAGAACTTG CAGGCCTTGT TTGTGGCTCT GAATGACCAG 1740

GTGTTTGAGA TCCGGGAGCT GGCCATCTGC ACTGTGGGCC GACTCAGTAG CATGAACCCT 1800

GCCTTTGTCA TGCCTTTCCT GCGCAAGATG CTCATCCAGA TTTTGACAGA GTTGGAGCAC 1860

AGTGGGATTG GAAGAATCAA AGAGCAGAGT GCCCGCATGC TGGGGCACCT GGTCTCCAAT 1920

GCCCCCCGAC TCATCCGCCC CTACATGGAG CCTATTCTGA AGGCATTAAT TTTGAAACTG 1980

AAAGACCCAG ACCCTGATCC AAACCCAGGT GTGATCAATA ATGTCCTGGC AACAATAGGA 2040

GAATTGGCAC AGGTTAGTGG CCTGGAAATG AGGAAATGGG TTGATGAACT TTTTATTATC 2100

ATCATGGACA TGCTCCAGGA TTCCTCTTTG TTGGCCAAAA GGCAGGTGGC TCTGTGGACC 2160

CTGGGACAGT TGGTGGCCAG CACTGGCTAT GTAGTAGAGC CCTACAGGAA GTACCCTACT 2220

TTGCTTGAGG TGCTACTGAA TTTTCTGAAG ACTGAGCAGA ACCAGGGTAC ACGCAGAGAG 2280

GCCATCCGTG TGTTAGGGCT TTTAGGGGCT TTGGATCCTT ACAAGCACAA AGTGAACATT 2340

GGCATGATAG ACCAGTCCCG GGATGCCTCT GCTGTCAGCC TGTCAGAATC CAAGTCAAGT 2400

CAGGATTCCT CTGACTATAG CACTAGTGAG ATGCTGGTCA ACATGGGAAA CTTGCCTCTG 2460

GATGAGTTCT ACCCAGCTGT GTCCATGGTG GCCCTGATGC GGATCTTCCG AGACCAGTCA 2520

CTCTCTCATC ATCACACCAT GGTTGTCCAG GCCATCACCT TCATCTTCAA GTCCCTGGGA 2580

CTCAAATGTG TGCAGTTCCT GCCCCAGGTC ATGCCCACGT TCCTTAATGT CATTCGAGTC 2640

TGTGATGGGG CCATCCGGGA ATTTTTGTTC CAGCAGCTGG GAATGTTGGT GTCCTTTGTG 2700

AAGAGCCACA TCAGACCTTA TATGGATGAA ATAGTCACCC TCATGAGAGA ATTCTGGGTC 2760

ATGAACACCT CAATTCAGAG CACGATCATT CTTCTCATTG AGCAAATTGT GGTAGCTCTT 2820

GGGGGTGAAT TTAAGCTCTA CCTGCCCCAG CTGATCCCAC ACATGCTGCG TGTCTTCATG 2880

CATGACAACA GCCCAGGCCG CATTGTCTCT ATCAAGTTAC TGGCTGCAAT CCAGCTGTTT 2940

GGCGCCAACC TGGATGACTA CCTGCATTTA CTGCTGCCTC CTATTGTTAA GTTGTTTGAT 3000

GCCCCTGAAG CTCCACTGCC ATCTCGAAAG GCAGCGCTAG AGACTGTGGA CCGCCTGACG 3060

GAGTCCTTGG ATTTCACTGA CTATGCCTCC CGGATCATTC ACCCTATTGT TCGAACACTG 3120

GACCAGAGCC CAGAACTGCG CTCCACAGCC ATGGACACGC TGTCTTCACT TGTTTTTCAG 3180

CTGGGGAAGA AGTACCAAAT TTTCATTCCA ATGGTGAATA AAGTTCTGGT GCGACACCGA 3240

ATCAATCATC AGCGCTACGA TGTGCTCATC TGCAGAATTG TCAAGGGATA CACACTTGCT 3300

GATGAAGAGG AGGATCCTTT GATTTACCAG CATCGGATGC TTAGGAGTGG CCAAGGGGAT 3360

GCATTGGCTA GTGGACCAGT GGAAACAGGA CCCATGAAGA AACTGCACGT CAGCACCATC 3420

AACCTCCAAA AGGCCTGGGG CGCTGCCAGG AGGGTCTCCA AAGATGACTG GCTGGAATGG 3480

CTGAGACGGC TGAGCCTGGA GCTGCTGAAG GACTCATCAT CGCCCTCCCT GCGCTCCTGC 3540

TGGGCCCTGG CACAGGCCTA CAACCCGATG GCCAGGGATC TCTTCAATGC TGCATTTGTG 3600

TCCTGCTGGT CTGAACTGAA TGAAGATCAA CAGGATGAGC TCATCAGAAG CATCGAGTTG 3660

GCCCTCACCT CACAAGACAT CGCTGAAGTC ACACAGACCC TCTTAAACTT GGCTGAATTC 3720

ATGGAACACA GTGACAAGGG CCCCCTGCCA CTGAGAGATG ACAATGGCAT TGTTCTGCTG 3780

GGTGAGAGAG CTGCCAAGTG CCGAGCATAT GCCAAAGCAC TACACTACAA AGAACTGGAG 3840

TTCCAGAAAG GCCCCACCCC TGCCATTCTA GAATCTCTCA TCAGCATTAA TAATAAGCTA 3900

CAGCAGCCGG AGGCAGCGGC CGGAGTGTTA GAATATGCCA TGAAACACTT TGGAGAGCTG 3960

GAGATCCAGG CTACCTGGTA TGAGAAACTG CACGAGTGGG AGGATGCCCT TGTGGCCTAT 4020

GACAAGAAAA TGGACACCAA CAAGGACGAC CCAGAGCTGA TGCTGGGCCG CATGCGCTGC 4080

CTCGAGGCCT TGGGGGAATG GGGTCAACTC CACCAGCAGT GCTGTGAAAA GTGGACCCTG 4140

GTTAATGATG AGACCCAAGC CAAGATGGCC CGGATGGCTG CTGCAGCTGC ATGGGGTTTA 4200

GGTCAGTGGG ACAGCATGGA AGAATACACC TGTATGATCC CTCGGGACAC CCATGATGGG 4260

GCATTTTATA GAGCTGTGCT GGCACTGCAT CAGGACCTCT TCTCCTTGGC ACAACAGTGC 4320

ATTGACAAGG CCAGGGACCT GCTGGATGCT GAATTAACTG CGATGGCAGG AGAGAGTTAC 4380

AGTCGGGCAT ATGGGGCCAT GGTTTCTTGC CACATGCTGT CCGAGCTGGA GGAGGTTATC 4440

CAGTACAAAC TTGTCCCCGA GCGACGAGAG ATCATCCGCC AGATCTGGTG GGAGAGACTG 4500

CAGGGCTGCC AGCGTATCGT AGAGGACTGG CAGAAAATCC TTATGGTGCG GTCCCTTGTG 4560

GTCAGCCCTC ATGAAGACAT GAGAACCTGG CTCAAGTATG CAAGCCTGTG TGGCAAGAGT 4620

GGCAGGCTGG CTCTTGCTCA TAAAACTTTA GTGTTGCTCC TGGGAGTTGA TCCGTCTCGG 4680

CAACTTGACC ATCCTCTGCC AACAGTTCAC CCTCAGGTGA CCTATGCCTA CATGAAAAAC 4740

ATGTGGAAGA GTGCCCGCAA GATCGATGCC TTCCAGCACA TGCAGCATTT TGTCCAGACC 4800

ATGCAGCAAC AGGCCCAGCA TGCCATCGCT ACTGAGGACC AGCAGCATAA GCAGGAACTG 4860

CACAAGCTCA TGGCCCGATG CTTCCTGAAA CTTGGAGAGT GGCAGCTGAA TCTACAGGGC 4920

ATCAATGAGA GCACAATCCC CAAAGTGCTG CAGTACTACA GCGCCGCCAC AGAGCACGAC 4980

CGCAGCTGGT ACAAGGCCTG GCATGCGTGG GCAGTGATGA ACTTCGAAGC TGTGCTACAC 5040

TACAAACATC AGAACCAAGC CCGCGATGAG AAGAAGAAAC TGCGTCATGC CAGCGGGGCC 5100

AACATCACCA ACGCCACCAC TGCCGCTACC ACGGCCGCCA CTGCCACCAC CACTGCCAGC 5160

ACCGAGGGCA GCAACAGTGA GAGCGAGGCC GAGAGCACCG AGAACAGCCC CACCCCATCG 5220

CCGCTGCAGA AGAAGGTCAC TGAGGATCTG TCCAAAACCC TCCTGATGTA CACGGTGCCT 5280

GCCGTCCAGG GCTTCTTCCG TTCCATCTCC TTGTCACGAG GCAACAACCT CCAGGATACA 5340

CTCAGAGTTC TCACCTTATG GTTTGATTAT GGTCACTGGC CAGATGTCAA TGAGGCCTTA 5400

GTGGAGGGGG TGAAAGCCAT CCAGATTGAT ACCTGGCTAC AGGTTATACC TCAGCTCATT 5460

GCAAGAATTG ATACGCCCAG ACCCTTGGTG GGACGTCTCA TTCACCAGCT TCTCACAGAC 5520

ATTGGTCGGT ACCACCCCCA GGCCCTCATC TACCCGCTGA CAGTGGCTTC TAAGTCTACC 5580

ACGACAGCCC GGCACAATGC AGCCAACAAG ATTCTGAAGA ACATGTGTGA GCACAGCAAC 5640

ACCCTGGTCC AGCAGGCCAT GATGGTGAGT GAGGAGCTGA TCCGAGTGGC CATCCTCTGG 5700

CATGAGATGT GGCATGAAGG CCTGGAAGAG GCATCTCGTT TGTACTTTGG GGAAAGGAAC 5760

GTGAAAGGCA TGTTTGAGGT GCTGGAGCCC TTGCATGCTA TGATGGAACG GGGCCCCCAG 5820

ACTCTGAAGG AAACATCCTT TAATCAGGCC TATGGTCGAG ATTTAATGGA GGCCCAAGAG 5880

TGGTGCAGGA AGTACATGAA ATCAGGGAAT GTCAAGGACC TCACCCAAGC CTGGGACCTC 5940

TATTATCATG TGTTCCGACG AATCTCAAAG CAGCTGCCTC AGCTCACATC CTTAGAGCTG 6000

CAATATGTTT CCCCAAAACT TCTGATGTGC CGGGACCTTG AATTGGCTGT GCCAGGAACA 6060

TATGACCCCA ACCAGCCAAT CATTCGCATT CAGTCCATAG CACCGTCTTT GCAAGTCATC 6120

ACATCCAAGC AGAGGCCCCG GAAATTGACA CTTATGGGCA GCAACGGGCA TGAGTTTGTT 6180

TTCCTTCTAA AAGGCCATGA AGATCTGCGC CAGGATGAGC GTGTGATGCA GCTCTTCGGC 6240

CTGGTTAACA CCCTTCTGGC CAATGACCCA ACATCTCTTC GGAAAAACCT CAGCATCCAG 6300

AGATATGCTG TCATCCCTTT ATCGACCAAC TCGGGCCTCA TTGGCTGGGT TCCCCACTGT 6360

GACACACTGC ACGCCCTCAT CCGGGACTAC AGGGAGAAGA AGAAGATCCT TCTCAACATC 6420

GAGCATCGCA TCATGTTGCG GATGGCTCCG GACTATGACC ACTTGACTCT GATGCAGAAG 6480

GTGGAGGTGT TTGAGCATGC CGTCAATAAT ACAGCTGGGG ACGACCTGGC CAAGCTGTTG 6540

TGGCTGAAAA GCCCCAGCTC TGAGGTGTGG TTTGACCGAA GAACCAATTA TACCCGTTCT 6600

TTAGCGGTCA TGTCAATGGT TGGGTATATT TTAGGCCTGG GAGATAGACA CCCATCCAAC 6660

CTGATGCTGG ACCGTCTGAG TGGGAAGATC CTGCACATTG ACTTTGGGGA CTGCTTTGAG 6720

GTTGCTATGA CCCGAGAGAA GTTTCCAGAG AAGATTCCAT TTAGACTAAC AAGAATGTTG 6780

ACCAATGCTA TGGAGGTTAC AGGCCTGGAT GGCAACTACA GAATCACATG CCACACAGTG 6840

ATGGAGGTGC TGCGAGAGCA CAAGGACAGT GTCATGGCCG TGCTGGAAGC CTTTGTCTAT 6900

GACCCCTTGC TGAACTGGAG GCTGATGGAC ACAAATACCA AAGGCAACAA GCGATCCCGA 6960

ACGAGGACGG ATTCCTACTC TGCTGGCCAG TCAGTCGAAA TTTTGGACGG TGTGGAACTT 7020

GGAGAGCCAG CCCATAAGAA AACGGGGACC ACAGTGCCAG AATCTATTCA TTCTTTCATT 7080

GGAGACGGTT TGGTGAAACC AGAGGCCCTA AATAAGAAAG CTATCCAGAT TATTAACAGG 7140

GTTCGAGATA AGCTCACTGG TCGGGACTTC TCTCATGATG ACACTTTGGA TGTTCCAACA 7200

CAAGTTGAGC TGCTCATCAA ACAAGCGACA TCCCATGAAA ACCTCTGCCA GTGCTATATT 7260

GGCTGGTGCC CTTTCTGGTA A 7281

Domain Profile

S: 1     iagfderveilaskqkpkklllrGsdgkeypyLvkgkeDlrqdervlqlfslvNtlLakd  60

         i+++++++++++skq+p+kl+l+Gs+g+e+++L+kg+eDlrqderv+qlf+lvNtlLa+d

Q: 2030  IQSIAPSLQVITSKQRPRKLTLMGSNGHEFVFLLKGHEDLRQDERVMQLFGLVNTLLAND  2089

         899*********************************************************

S: 61    ketsrrkLkirtykVvplstrsgliewventvsLkellkklvekkavlldqpisyrykdl  120

         +++ r++L+i++y+V+plst+sgli+wv+++++L++l+++++ekk++ll+        ++

Q: 2090  PTSLRKNLSIQRYAVIPLSTNSGLIGWVPHCDTLHALIRDYREKKKILLN-------IEH  2142

         *************************************************9.......9**

S: 121   stvqarkpklkhlkls..levfkevlenlvpkdllkklllekfpspeewfelrkaytrsl  178

         +++ +++p+++hl+l+  +evf+++++n ++ d l+kll+ k+ps+e+wf++r++ytrsl

Q: 2143  RIMLRMAPDYDHLTLMqkVEVFEHAVNN-TAGDDLAKLLWLKSPSSEVWFDRRTNYTRSL  2201

         ****************************.999****************************

S: 179   AvislvgyiLgLgdrhlenllidqetgevvhidfgvafekaktqlkvpekvPFRLTrniv  238

         Av+s+vgyiLgLgdrh++nl++d+ +g+++hidfg +fe a+t++k+pek+PFRLTr+++

Q: 2202  AVMSMVGYILGLGDRHPSNLMLDRLSGKILHIDFGDCFEVAMTREKFPEKIPFRLTRMLT  2261

         ************************************************************

S: 239   nalgvtgveGvfrasceavlrvlreskeklltiLevflydplvdwkkkkktsketeeela  298

         na++vtg++G++r++c++v++vlre+k++++++Le+f+ydpl++w+ +++++k+++++++

Q: 2262  NAMEVTGLDGNYRITCHTVMEVLREHKDSVMAVLEAFVYDPLLNWRLMDTNTKGNKRSRT  2321

         ************************************************************

S: 299   ekakaealkikkllskvekaenavatrdlllle  331

         ++++++a +++++l++ve +e+a+++++++++e

Q: 2322  RTDSYSAGQSVEILDGVELGEPAHKKTGTTVPE  2354

         ****************************99987

Domain Sequence
(FASTA)

IQSIAPSLQV ITSKQRPRKL TLMGSNGHEF VFLLKGHEDL RQDERVMQLF GLVNTLLAND 60

PTSLRKNLSI QRYAVIPLST NSGLIGWVPH CDTLHALIRD YREKKKILLN IEHRIMLRMA 120

PDYDHLTLMQ KVEVFEHAVN NTAGDDLAKL LWLKSPSSEV WFDRRTNYTR SLAVMSMVGY 180

ILGLGDRHPS NLMLDRLSGK ILHIDFGDCF EVAMTREKFP EKIPFRLTRM LTNAMEVTGL 240

DGNYRITCHT VMEVLREHKD SVMAVLEAFV YDPLLNWRLM DTNTKGNKRS RTRTDSYSAG 300

QSVEILDGVE LGEPAHKKTG TTVPE 325

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Rattus norvegicus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0008144	; F:drug binding
GO:0016301	; F:kinase activity
GO:0016773	; F:phosphotransferase activity, alcohol group as acceptor

KEGG

InterPros

IPR011989	; ARM-like.
IPR016024	; ARM-type_fold.
IPR024585	; DUF3385_TOR.
IPR003152	; FATC.
IPR011009	; Kinase-like_dom.
IPR000403	; PI3/4_kinase_cat_dom.
IPR018936	; PI3/4_kinase_CS.
IPR003151	; PIK-rel_kinase_FAT.
IPR014009	; PIK_FAT.
IPR009076	; Rapamycin-bd_dom.
IPR026683	; TOR/Smg1.

Pfam

PF11865	; DUF3385; 1.
PF02259	; FAT; 1.
PF02260	; FATC; 1.
PF00454	; PI3_PI4_kinase; 1.
PF08771	; Rapamycin_bind; 1.

SMARTs

SM00146

; PI3Kc; 1.

Prosites

PS51189	; FAT; 1.
PS51190	; FATC; 1.
PS00915	; PI3_4_KINASE_1; 1.
PS00916	; PI3_4_KINASE_2; 1.
PS50290	; PI3_4_KINASE_3; 1.

Prints

Created Date

20-Feb-2013