EPS-GOG-00011

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-GOG-00011

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
DSP/aDSP	165.4	9.6E-49	174	320	147

Status

Unreviewed

Ensembl Protein

ENSGGOP00000010742

UniProt Accession

G3R607;

Protein Name

Protein Synonyms/Alias

Gene Name

DUSP13

Gene Synonyms/Alias

DUSP13;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSGGOG00000011021	ENSGGOP00000010742	ENSGGOT00000011062

Organism

Gorilla gorilla

Functional Description

Protein Length

327

Protein Sequence
(FASTA)

MGLPQPRLPA PALQAGPATA GCRPELRGQS WSLLPAMGLC HFATLALILL VLLEALAQAD 60

TQKMVEAQRG VSPRACYSIW LLLAPAPPLS HCLQSPQKQH QVCGDRRLKA GSTNCPSEKC 120

TARARYSHRM DSLQKQDLRR PKIHGAVRAS PYQPPTLASL QRLLWVRQAA TLNHIDEVWP 180

SLFLGDAYAA RDKSKLIQLG ITHVVNAAAG KFQVDTGAKF YRGMSLEYYG IEADDNPFFD 240

LSVYFLPVAR YIRAAFSVPQ GRVLVHCAMG VSRSATLVLA FLMIYENMTL VEAIQTVQAH 300

RNICPNSGFL RQLQVLDNRL GRETGQF 327

Nucleotide Sequence
(FASTA)

ATGGGTCTTC CCCAACCGAG GCTTCCTGCA CCAGCTCTGC AGGCTGGACC AGCAACTGCG 60

GGGTGCCGGC CAGAGCTGAG GGGCCAGAGC TGGTCCTTAC TCCCTGCCAT GGGGCTCTGC 120

CACTTTGCCA CCCTGGCACT GATCCTGCTG GTGCTGCTGG AGGCTCTGGC CCAGGCGGAC 180

ACACAGAAGA TGGTGGAAGC CCAGCGTGGG GTCAGCCCTA GAGCCTGCTA CTCCATCTGG 240

CTCCTCCTGG CGCCTGCACC CCCTCTCAGC CACTGTCTTC AGTCTCCACA GAAACAGCAT 300

CAAGTGTGCG GAGACAGGCG GCTGAAAGCC GGCAGCACAA ACTGCCCGTC AGAGAAGTGC 360

ACAGCCCGGG CCAGATACTC CCACAGGATG GACTCACTGC AGAAGCAGGA CCTCCGGAGG 420

CCCAAGATCC ACGGGGCAGT CCGGGCATCT CCCTACCAGC CGCCCACGTT GGCTTCGCTG 480

CAGCGCTTGC TGTGGGTCCG TCAGGCTGCC ACACTAAACC ATATCGACGA GGTCTGGCCC 540

AGCCTCTTCC TGGGAGATGC GTACGCAGCC CGGGACAAGA GCAAACTGAT CCAGCTGGGA 600

ATCACCCACG TTGTGAATGC CGCTGCGGGC AAGTTCCAGG TGGACACAGG TGCCAAATTC 660

TACCGTGGAA TGTCCCTGGA GTACTATGGC ATCGAGGCGG ATGACAACCC CTTCTTCGAC 720

CTCAGTGTCT ACTTTCTGCC TGTTGCTCGA TACATCCGAG CTGCCTTCAG TGTTCCCCAA 780

GGCCGCGTGC TGGTACACTG TGCCATGGGG GTAAGCCGCT CTGCCACACT TGTCCTGGCC 840

TTCCTCATGA TCTATGAGAA CATGACGCTG GTAGAGGCCA TCCAGACGGT GCAGGCCCAC 900

CGCAATATCT GCCCTAACTC AGGCTTCCTC CGGCAGCTCC AGGTTCTGGA CAACCGACTG 960

GGGCGGGAGA CGGGGCAGTT CTGA 984

Domain Profile

S: 1     evteilpglylgdqataldrreLsklgitvvinaslsvikvqviPeylikkgityknipv  60

         +++e++p+l+lgd+  a d+ +L +lgit+v+na+++ ++v+++ ++++ ++ +y +i++

Q: 174   HIDEVWPSLFLGDAYAARDKSKLIQLGITHVVNAAAGKFQVDTGAKFYRGMSLEYYGIEA  233

         699*********************************************************

S: 61    dDsdvtdllqyfdeaaefidea.kekggkvlvHCaaGvsRSatlvlaYLmkveglslsdA  119

         dD++ +dl+ yf ++a++i  a + ++g+vlvHCa+GvsRSatlvla+Lm++e+++l++A

Q: 234   DDNPFFDLSVYFLPVARYIRAAfSVPQGRVLVHCAMGVSRSATLVLAFLMIYENMTLVEA  293

         *********************999************************************

S: 120   ieavkrkrpsiepnegfleQLlelekkl  147

         i++v+++r +i+pn+gfl+QL  l+++l

Q: 294   IQTVQAHR-NICPNSGFLRQLQVLDNRL  320

         ********.****************987

Domain Sequence
(FASTA)

HIDEVWPSLF LGDAYAARDK SKLIQLGITH VVNAAAGKFQ VDTGAKFYRG MSLEYYGIEA 60

DDNPFFDLSV YFLPVARYIR AAFSVPQGRV LVHCAMGVSR SATLVLAFLM IYENMTLVEA 120

IQTVQAHRNI CPNSGFLRQL QVLDNRL 147

Keyword

Complete proteome; Hydrolase; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0004725	; F:protein tyrosine phosphatase activity
GO:0008138	; F:protein tyrosine/serine/threonine phosphatase activity
GO:0035335	; P:peptidyl-tyrosine dephosphorylation

KEGG

InterPros

IPR020417	; Atypical_DUSP.
IPR020405	; Atypical_DUSP_famA.
IPR000340	; Dual-sp_phosphatase_cat-dom.
IPR020422	; Dual-sp_phosphatase_subgr_cat.
IPR024950	; DUSP.
IPR000387	; Tyr/Dual-specificity_Pase.
IPR016130	; Tyr_Pase_AS.

Pfam

PF00782

; DSPc; 1.

SMARTs

SM00195

; DSPc; 1.

Prosites

PS00383	; TYR_PHOSPHATASE_1; 1.
PS50056	; TYR_PHOSPHATASE_2; 1.
PS50054	; TYR_PHOSPHATASE_DUAL; 1.

Prints

PR01908	; ADSPHPHTASE.
PR01909	; ADSPHPHTASEA.

Created Date

20-Feb-2013