EKS-GOG-00063

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-GOG-00063

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDK	372.1	2.2E-111	21	317	297

Status

Unreviewed

Ensembl Protein

ENSGGOP00000010772

UniProt Accession

G3R636;

Protein Name

Protein Synonyms/Alias

Gene Name

CDK9

Gene Synonyms/Alias

CDK9;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSGGOG00000011054	ENSGGOP00000010772	ENSGGOT00000011093

Organism

Gorilla gorilla

Functional Description

Protein Length

374

Protein Sequence
(FASTA)

AAMAKQYDSV ECPFCDEVSK YEKLAKIGQG TFGEVFKARH RKTGQKVALK KVLMENEKEG 60

FPITALREIK ILQLLKHENV VNLIEICRTK ASPYNRCKGS IYLVFDFCEH DLAGLLSNVL 120

VKFTLSEIKR VMQMLLNGLY YIHRNKILHR DMKAANVLIT RDGVLKLADF GLARAFSLAK 180

NSQPNRYTNR VVTLWYRPPE LLLGERDYGP PIDLWGAGCI MAEMWTRSPI MQGNTEQHQL 240

ALISQLCGSI TPEVWPNVDN YELYEKLELV KGQKRKVKDR LKAYVRDPYA LDLIDKLLVL 300

DPAQRIDSDD ALNHDFFWSD PMPSDLKGML STHLTSMFEY LAPPRRKGSQ ITQQSTNQSR 360

NPATTNQTEF ERVF 374

Nucleotide Sequence
(FASTA)

GCGGCCATGG CAAAGCAGTA CGACTCGGTG GAGTGCCCTT TTTGTGATGA AGTTTCCAAA 60

TACGAGAAGC TCGCCAAAAT CGGCCAAGGC ACCTTCGGGG AGGTGTTTAA GGCCAGGCAC 120

CGCAAGACCG GCCAGAAGGT GGCTCTGAAG AAGGTGCTGA TGGAAAATGA GAAGGAGGGG 180

TTCCCCATTA CAGCCTTGCG GGAGATCAAG ATCCTTCAGC TTCTAAAACA CGAGAATGTG 240

GTCAACTTGA TTGAGATTTG TCGAACCAAA GCTTCCCCCT ATAACCGCTG CAAGGGTAGT 300

ATATACCTGG TGTTCGACTT CTGCGAGCAT GACCTTGCTG GGCTGTTGAG CAATGTTTTG 360

GTCAAGTTCA CGCTGTCTGA GATCAAGAGG GTGATGCAGA TGCTGCTTAA CGGCCTCTAC 420

TACATCCACA GAAACAAGAT CCTGCATAGG GACATGAAGG CGGCTAATGT GCTTATCACT 480

CGTGATGGGG TCCTGAAGCT GGCAGACTTT GGGCTGGCCC GGGCCTTCAG CCTGGCCAAG 540

AACAGCCAGC CCAACCGCTA CACCAACCGT GTGGTGACAC TCTGGTACCG GCCCCCGGAG 600

CTGTTGCTCG GGGAGCGGGA CTACGGCCCC CCCATTGACC TGTGGGGTGC TGGGTGCATC 660

ATGGCAGAGA TGTGGACCCG CAGCCCCATC ATGCAGGGCA ACACGGAGCA GCACCAACTC 720

GCCCTCATCA GTCAGCTCTG CGGCTCCATC ACCCCTGAGG TGTGGCCAAA CGTGGACAAC 780

TATGAGCTGT ATGAAAAGCT GGAGCTGGTC AAGGGCCAGA AGCGGAAGGT GAAGGACAGG 840

CTGAAGGCCT ATGTGCGTGA CCCATACGCA CTGGACCTCA TCGACAAGCT GCTGGTGCTG 900

GACCCTGCCC AGCGCATCGA CAGCGATGAC GCCCTCAACC ACGACTTCTT CTGGTCCGAC 960

CCCATGCCCT CCGACCTCAA GGGCATGCTC TCCACCCACC TGACGTCCAT GTTCGAGTAC 1020

TTGGCACCAC CGCGCCGGAA GGGCAGCCAG ATCACCCAGC AGTCCACCAA CCAGAGTCGC 1080

AATCCCGCCA CCACCAACCA GACGGAGTTT GAGCGCGTCT TCTGA 1125

Domain Profile

S: 1     yeklekigeGtygkvykakdketgevvAlKkirlekekegvpitalrEisllkelkhkni  60

         yekl+kig+Gt+g+v+ka++++tg++vAlKk+ +e+ekeg+pitalrEi++l+ lkh+n+

Q: 21    YEKLAKIGQGTFGEVFKARHRKTGQKVALKKVLMENEKEGFPITALREIKILQLLKHENV  80

         99**********************************************************

S: 61    vkLlevva.......kdkkklyLvfefleqdLkkllkkkkkkklsleevkslllqllegl  113

         v+L+e++        + k ++yLvf+f+e+dL+ ll++    k++l+e+k+++++ll+gl

Q: 81    VNLIEICRtkaspynRCKGSIYLVFDFCEHDLAGLLSNVLV-KFTLSEIKRVMQMLLNGL  139

         ********99999988889*********************9.******************

S: 114   aylHsnkilHRDlKpqNlLiskegklklaDfGlaraf....ssplktytkevvTlwYraP  169

          y+H+nkilHRD+K++N+Li+++g+lklaDfGlaraf    +s+ ++yt++vvTlwYr+P

Q: 140   YYIHRNKILHRDMKAANVLITRDGVLKLADFGLARAFslakNSQPNRYTNRVVTLWYRPP  199

         *************************************7776555557*************

S: 170   elLlgakeYstavDiWsvgcilaelltrkplfqgkseidqlerifkllgtpsekvwpevs  229

         elLlg+++Y+  +D+W++gci+ae++tr+p++qg++e++ql  i++l+g+++ +vwp+v

Q: 200   ELLLGERDYGPPIDLWGAGCIMAEMWTRSPIMQGNTEQHQLALISQLCGSITPEVWPNVD  259

         ************************************************************

S: 230   klpeyk.ksfpkkkkkklkekvkklkek..aldllekllaldpkkRisakealqhkyf  284

         +++ y+  ++ k +k+k+k+++k++ ++  aldl++kll ldp++Ri++++al+h++f

Q: 260   NYELYEkLELVKGQKRKVKDRLKAYVRDpyALDLIDKLLVLDPAQRIDSDDALNHDFF  317

         ******7799999999999999887755469*************************98

Domain Sequence
(FASTA)

YEKLAKIGQG TFGEVFKARH RKTGQKVALK KVLMENEKEG FPITALREIK ILQLLKHENV 60

VNLIEICRTK ASPYNRCKGS IYLVFDFCEH DLAGLLSNVL VKFTLSEIKR VMQMLLNGLY 120

YIHRNKILHR DMKAANVLIT RDGVLKLADF GLARAFSLAK NSQPNRYTNR VVTLWYRPPE 180

LLLGERDYGP PIDLWGAGCI MAEMWTRSPI MQGNTEQHQL ALISQLCGSI TPEVWPNVDN 240

YELYEKLELV KGQKRKVKDR LKAYVRDPYA LDLIDKLLVL DPAQRIDSDD ALNHDFF 297

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013