EPS-GOG-00018

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-GOG-00018

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
DSP/aDSP	132.2	1.7E-38	4	135	132

Status

Unreviewed

Ensembl Protein

ENSGGOP00000011557

UniProt Accession

G3R857;

Protein Name

Protein Synonyms/Alias

Gene Name

DUSP15

Gene Synonyms/Alias

DUSP15;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSGGOG00000011846	ENSGGOP00000011557	ENSGGOT00000011892

Organism

Gorilla gorilla

Functional Description

Protein Length

295

Protein Sequence
(FASTA)

MTEGVLPGLY LGNFIDAKDL DQLGRNKITH IISIHESPQP LLQDITYLRI PVADTPEVPI 60

KKHFKECINF IHCCRLNGGN CLVHCFAGIS RSTTIVTAYV MTVTGLGWRD VLEAIKATRP 120

IANPNPGFRQ QLEEFGWASS RKGARHRTPK TPGAQCPPMT SATCLLAARV ALLSAALVRE 180

ATGRTAQRCR LSPRAAAERL LGPPPHVAAG WSPDPKYQIC LCFGEEDPGP TEHPKEQLIM 240

ADVQVQLRPG SSSCTLSAST ERPEGSSTPG NPDGITHLQR SCLHPKRAAY SSCTR 295

Nucleotide Sequence
(FASTA)

ATGACCGAAG GGGTACTTCC TGGACTCTAC CTCGGAAACT TCATTGATGC CAAAGACCTG 60

GATCAGCTGG GCCGAAATAA GATCACACAC ATCATCTCTA TCCATGAGTC ACCCCAGCCT 120

CTGCTGCAGG ATATCACCTA CCTTCGCATC CCGGTGGCTG ATACCCCTGA GGTACCCATC 180

AAAAAGCACT TCAAAGAATG TATCAACTTC ATCCACTGCT GCCGCCTTAA TGGGGGGAAC 240

TGCCTTGTGC ACTGCTTTGC AGGCATCTCT CGCAGCACCA CGATTGTGAC AGCGTATGTG 300

ATGACTGTGA CGGGGCTAGG CTGGCGGGAC GTGCTTGAAG CCATCAAGGC CACCAGGCCC 360

ATCGCCAACC CCAACCCAGG CTTTAGGCAG CAGCTTGAAG AGTTTGGCTG GGCCAGTTCC 420

CGGAAGGGTG CCAGGCATAG GACCCCAAAA ACCCCTGGTG CCCAATGCCC TCCGATGACT 480

TCAGCAACCT GCCTGCTGGC TGCACGTGTG GCTCTTCTCT CCGCAGCGCT GGTGCGTGAA 540

GCCACCGGGC GCACAGCCCA GCGCTGTCGT CTGAGTCCGC GGGCGGCCGC CGAGCGCCTG 600

CTGGGGCCGC CACCTCACGT TGCAGCAGGA TGGTCACCGG ACCCAAAGTA CCAGATCTGT 660

CTGTGCTTTG GTGAGGAGGA CCCGGGCCCC ACAGAGCACC CCAAGGAGCA GCTCATCATG 720

GCGGACGTGC AGGTGCAGCT TCGGCCTGGG AGCTCGTCCT GCACTCTAAG TGCCTCAACC 780

GAGCGCCCAG AAGGGTCCTC AACCCCTGGC AACCCCGATG GCATCACTCA CCTTCAACGC 840

AGCTGCCTCC ATCCTAAGCG AGCCGCTTAC TCCTCTTGTA CCCGCTGA 888

Domain Profile

S: 4     eilpglylgdqataldrreLsklgitvvinaslsvikvqviPeylikkgityknipvdDs  63

          +lpglylg+ ++a d  +L +++it++i  +++  +       l  ++ity++ipv D+

Q: 4     GVLPGLYLGNFIDAKDLDQLGRNKITHIIS-IHESPQ------PL-LQDITYLRIPVADT  55

         599*******************99999996.455555......33.68************

S: 64    dvtdllqyfdeaaefideakekggkvlvHCaaGvsRSatlvlaYLmkveglslsdAieav  123

         ++  + ++f+e+++fi+ ++ +gg++lvHC aG+sRS+t+v+aY+m+v+gl ++d++ea+

Q: 56    PEVPIKKHFKECINFIHCCRLNGGNCLVHCFAGISRSTTIVTAYVMTVTGLGWRDVLEAI  115

         ************************************************************

S: 124   krkrpsiepnegfleQLlel  143

         k++rp+++pn gf +QL e+

Q: 116   KATRPIANPNPGFRQQLEEF  135

         *****************998

Domain Sequence
(FASTA)

GVLPGLYLGN FIDAKDLDQL GRNKITHIIS IHESPQPLLQ DITYLRIPVA DTPEVPIKKH 60

FKECINFIHC CRLNGGNCLV HCFAGISRST TIVTAYVMTV TGLGWRDVLE AIKATRPIAN 120

PNPGFRQQLE EF 132

Keyword

Complete proteome; Hydrolase; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Taeniopygia guttata"; ?>Tursiops truncatus"; ?>

Gene Ontology

GO:0004725	; F:protein tyrosine phosphatase activity
GO:0008138	; F:protein tyrosine/serine/threonine phosphatase activity
GO:0035335	; P:peptidyl-tyrosine dephosphorylation

KEGG

InterPros

IPR020417	; Atypical_DUSP.
IPR000340	; Dual-sp_phosphatase_cat-dom.
IPR020422	; Dual-sp_phosphatase_subgr_cat.
IPR024950	; DUSP.
IPR017855	; SMAD_dom-like.
IPR008984	; SMAD_FHA_domain.
IPR000387	; Tyr/Dual-specificity_Pase.
IPR016130	; Tyr_Pase_AS.

Pfam

PF00782

; DSPc; 1.

SMARTs

SM00195

; DSPc; 1.

Prosites

PS00383	; TYR_PHOSPHATASE_1; 1.
PS50056	; TYR_PHOSPHATASE_2; 1.
PS50054	; TYR_PHOSPHATASE_DUAL; 1.

Prints

PR01908

; ADSPHPHTASE.

Created Date

20-Feb-2013