EKS-GOG-00340

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-GOG-00340

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/DCAMKL	449.1	6.2E-135	411	670	260

Status

Unreviewed

Ensembl Protein

ENSGGOP00000013678

UniProt Accession

G3RDR8;

Protein Name

Protein Synonyms/Alias

Gene Name

DCLK2

Gene Synonyms/Alias

DCLK2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSGGOG00000014019	ENSGGOP00000013678	ENSGGOT00000014072

Organism

Gorilla gorilla

Functional Description

Protein Length

785

Protein Sequence
(FASTA)

MASTRSIELE HFEERDKRPR PGSRRGAPSS SGGSSSSGPK GNGLIPSPAH SAHCSFYRTR 60

TLQALSSEKK AKKARFYRNG DRYFKGLVFA ISSDRFRSFD ALLIELTRSL SDNVNLPQGV 120

RTIYTIDGSR KVTSLDELLE GESYVCASNE PFRKVDYTKN INPNWSVNIK GGTSRALAAA 180

SSVKSEVKES KDFIKPKLVT VIRSGVKPRK AVRILLNKKT AHSFEQVLTD ITEAIKLDSG 240

VVKRLCTLDG KQVTCLQDFF GDDDVFIACG PEKFRYAQDD FVLDHSECRV LKSSYSRSSA 300

VKYSGSKSPG PSRRSKSPAS VKRGGHYSSA YSTAKSPVNG TPSSQLSTPK STKSSSSSPT 360

SPGSFRGLKQ ISAHGRSSSN VNGGPELDRC ISPEGVNGNR CSESSTLLEK YKIGKVIGDG 420

NFAVVKECID RSTGKEFALK IIDKAKCCGK EHLIENEVSI LRRVKHPNII MLVEEMETAT 480

ELFLVMELVK GGDLFDAITS STKYTERDGS AMVYNLANAL RYLHGLSIVH RDIKPENLLV 540

CEYPDGTKSL KLGDFGLATV VEGPLYTVCG TPTYVAPEII AETGYGLKVD IWAAGVITYI 600

LLCGFPPFRR LSENNLQEDL FDQILAGKLE FPAPYWDNIT DSAKELISQM LQVNVEARCT 660

AGQILSHPWV SDDASQENNM QAEVTGKLKQ HFNNALPKQN STTTGVSVIM NTALDKEGQI 720

FCSKHCQDSG RPGMEPISPV PPSVEETPVP GEAVPAPTPP ESPTPHCPPA ATGGERAGTW 780

RRHRD 785

Nucleotide Sequence
(FASTA)

ATGGCCAGCA CCAGGAGTAT CGAGCTGGAG CACTTTGAGG AACGGGACAA AAGGCCGCGG 60

CCGGGGTCGC GGAGAGGGGC CCCCAGCTCC TCCGGGGGCA GCAGCAGCTC CGGCCCCAAG 120

GGGAACGGGC TCATCCCCAG TCCGGCGCAC AGTGCCCACT GCAGCTTCTA CCGCACGCGG 180

ACCCTGCAGG CCCTCAGCTC GGAGAAGAAG GCCAAGAAGG CGCGCTTCTA CCGGAACGGG 240

GACCGCTACT TCAAGGGCCT GGTGTTTGCC ATCTCCAGCG ACCGCTTCCG GTCCTTCGAT 300

GCGCTCCTCA TAGAGCTCAC CCGCTCCCTG TCGGACAACG TGAACCTGCC CCAGGGTGTC 360

CGCACTATCT ACACCATCGA CGGCAGCCGG AAGGTCACCA GCCTGGACGA GCTGCTGGAA 420

GGTGAGAGTT ACGTGTGTGC ATCCAATGAA CCATTTCGTA AAGTCGATTA CACCAAAAAT 480

ATTAATCCAA ACTGGTCTGT GAACATCAAG GGTGGGACAT CCCGAGCCCT GGCTGCTGCC 540

TCCTCTGTGA AAAGTGAAGT AAAAGAAAGT AAAGATTTCA TCAAACCCAA GTTAGTGACT 600

GTGATTCGAA GTGGAGTGAA GCCTAGAAAA GCCGTGCGGA TCCTTCTGAA TAAAAAGACT 660

GCTCATTCCT TTGAACAAGT CTTAACAGAT ATCACCGAAG CCATTAAACT AGACTCAGGA 720

GTCGTCAAGA GGCTCTGCAC CCTGGATGGA AAGCAGGTTA CTTGTCTGCA AGACTTTTTT 780

GGTGATGACG ATGTTTTTAT TGCATGTGGA CCAGAAAAAT TCCGTTATGC CCAAGATGAC 840

TTTGTCCTGG ATCATAGTGA ATGTCGTGTC CTGAAGTCAT CTTATTCTCG ATCCTCAGCT 900

GTTAAGTATT CTGGATCCAA AAGCCCTGGG CCCTCTCGAC GCAGCAAATC ACCAGCTTCA 960

GTAAAGCGGG GTGGCCACTA CTCCAGTGCC TATTCTACAG CCAAATCCCC AGTTAATGGA 1020

ACTCCCAGCA GCCAACTTTC TACTCCTAAA TCTACGAAAT CCTCCAGTTC CTCTCCAACT 1080

AGTCCAGGAA GTTTCAGAGG ATTAAAGCAG ATTTCTGCTC ATGGCAGATC TTCTTCCAAT 1140

GTAAACGGTG GACCTGAGCT TGACCGTTGC ATAAGTCCTG AAGGTGTGAA TGGAAACAGA 1200

TGCTCTGAAT CATCAACTCT TCTTGAGAAA TACAAAATTG GAAAGGTCAT TGGTGATGGC 1260

AATTTTGCAG TAGTCAAAGA GTGTATAGAC AGGTCCACTG GAAAGGAGTT TGCCCTAAAG 1320

ATTATAGACA AAGCCAAATG TTGTGGAAAG GAACACCTGA TTGAGAATGA AGTGTCAATA 1380

CTGCGCCGAG TGAAACATCC CAATATCATT ATGCTGGTCG AGGAGATGGA AACAGCAACT 1440

GAGCTCTTTC TGGTGATGGA ATTGGTCAAA GGTGGAGATC TCTTTGATGC AATTACTTCG 1500

TCGACCAAGT ACACTGAGAG AGATGGCAGT GCCATGGTGT ACAACTTAGC CAATGCCCTC 1560

AGGTATCTCC ATGGCCTCAG CATCGTGCAC AGAGACATCA AACCAGAGAA TCTCTTGGTG 1620

TGTGAATATC CTGATGGAAC CAAGTCTTTG AAACTGGGAG ACTTTGGGCT TGCGACTGTG 1680

GTAGAAGGCC CTTTATACAC AGTCTGTGGC ACACCCACTT ATGTGGCTCC AGAAATCATT 1740

GCTGAAACTG GCTATGGCCT GAAGGTGGAC ATTTGGGCAG CTGGTGTGAT CACATACATA 1800

CTTCTCTGTG GATTCCCACC ATTCCGAAGG CTTAGTGAGA ACAATCTCCA GGAAGATCTC 1860

TTCGACCAGA TCTTGGCTGG GAAGCTGGAG TTTCCGGCCC CCTACTGGGA TAACATCACG 1920

GACTCTGCCA AGGAATTGAT CAGTCAAATG CTTCAGGTAA ATGTTGAAGC TCGGTGTACC 1980

GCGGGACAAA TCCTGAGTCA CCCCTGGGTG TCAGATGATG CCTCCCAGGA GAATAACATG 2040

CAAGCTGAGG TGACAGGTAA ACTAAAACAG CACTTTAATA ATGCGCTTCC CAAACAGAAC 2100

AGCACTACCA CCGGGGTCTC CGTCATCATG AACACGGCTC TAGATAAGGA GGGGCAGATT 2160

TTCTGCAGCA AGCACTGTCA AGACAGCGGC AGGCCTGGGA TGGAGCCCAT CTCTCCAGTT 2220

CCTCCCTCAG TGGAGGAGAC CCCTGTGCCT GGGGAAGCAG TCCCGGCCCC CACCCCTCCG 2280

GAATCTCCCA CCCCCCACTG TCCTCCCGCT GCCACGGGTG GTGAGCGGGC AGGAACCTGG 2340

CGCCGCCACC GAGACTGA 2358

Domain Profile

S: 1     yeigrviGdGnfavvkevreretgkeyalkiidksklkGkehlidneveilkkvkhpniv  60

         y+ig+viGdGnfavvke+++r+tgke+alkiidk+k++Gkehli+nev+il++vkhpni+

Q: 411   YKIGKVIGDGNFAVVKECIDRSTGKEFALKIIDKAKCCGKEHLIENEVSILRRVKHPNII  470

         9***********************************************************

S: 61    klieeletetelylvlelvkgGdlfdaitkstkleerdaaimilelakalkylhelnivh  120

         +l+ee+et+tel+lv+elvkgGdlfdait+stk++erd+++m+++la+al+ylh l+ivh

Q: 471   MLVEEMETATELFLVMELVKGGDLFDAITSSTKYTERDGSAMVYNLANALRYLHGLSIVH  530

         ************************************************************

S: 121   rdvkpenllvvekedgskslkladfGlaaevegplytvcGtPtyvaPeilaetGyglkvd  180

         rd+kpenllv+e+ dg+kslkl+dfGla++vegplytvcGtPtyvaPei+aetGyglkvd

Q: 531   RDIKPENLLVCEYPDGTKSLKLGDFGLATVVEGPLYTVCGTPTYVAPEIIAETGYGLKVD  590

         ************************************************************

S: 181   iWaaGvilyillvGfpPfr..ssdedqeelfdlilsgklefpsPyWdnisdkakdlvsrl  238

         iWaaGvi+yill+GfpPfr  s+++ qe+lfd+il+gklefp+PyWdni+d+ak+l+s++

Q: 591   IWAAGVITYILLCGFPPFRrlSENNLQEDLFDQILAGKLEFPAPYWDNITDSAKELISQM  650

         ******************9778999***********************************

S: 239   levdeekrltaeqilehpwv  258

         l+v++e+r+ta qil+hpwv

Q: 651   LQVNVEARCTAGQILSHPWV  670

         *******************8

Domain Sequence
(FASTA)

YKIGKVIGDG NFAVVKECID RSTGKEFALK IIDKAKCCGK EHLIENEVSI LRRVKHPNII 60

MLVEEMETAT ELFLVMELVK GGDLFDAITS STKYTERDGS AMVYNLANAL RYLHGLSIVH 120

RDIKPENLLV CEYPDGTKSL KLGDFGLATV VEGPLYTVCG TPTYVAPEII AETGYGLKVD 180

IWAAGVITYI LLCGFPPFRR LSENNLQEDL FDQILAGKLE FPAPYWDNIT DSAKELISQM 240

LQVNVEARCT AGQILSHPWV 260

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Danio rerio"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gallus gallus"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005622	; C:intracellular
GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity
GO:0035556	; P:intracellular signal transduction

KEGG

InterPros

IPR020636	; Ca/CaM-dep_Ca-dep_prot_Kinase.
IPR003533	; Doublecortin_dom.
IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF03607	; DCX; 2.
PF00069	; Pkinase; 1.

SMARTs

SM00537	; DCX; 2.
SM00220	; S_TKc; 1.

Prosites

PS50309	; DC; 2.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013