EPS-GOG-00072

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-GOG-00072

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
DSP/PTEN	287.0	9.9E-86	123	293	171

Status

Unreviewed

Ensembl Protein

ENSGGOP00000022783

UniProt Accession

G3RFX5;

Protein Name

Protein Synonyms/Alias

Gene Name

TENC1

Gene Synonyms/Alias

TENC1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSGGOG00000014860	ENSGGOP00000022783	ENSGGOT00000026653
ENSGGOG00000014860	ENSGGOP00000014508	ENSGGOT00000014921

Organism

Gorilla gorilla

Functional Description

Protein Length

1409

Protein Sequence
(FASTA)

MKSSGPVERL LRALGRRDSS RATSRPRKAE PHSFREKVFR KKPPVCAVCK VTIDGTGISC 60

RVCKVATHRK CEAKVTSACQ ALPPVELRRN TAPVRRIEHL GSTKSLNHSK QRSTLPRSFS 120

LDPLMERRWD LDLTYVTERI LAAAFPARPD EQRHRGHLRE LAHVLQSKHR DKYLLFNLSE 180

KRHDLTRLNP KVQDFGWPEL HAPPLDKLCS ICKAMETWLS ADPQHVVVLY CKGNKGKLGV 240

IVSAYMHYSK ISAGADQALA TLTMRKFCED KVATELQPSQ RRYISYFSGL LSGSIRMNSS 300

PLFLHYVLIP MLPAFEPGTG FQPFLKIYQS MQLVYTSGVY HIAGPGPQQL CISLEPALLL 360

KGDVMVTCYH KGGRGTDRTL VFRVQFHTCT IHGPQLTFPK DQLDEAWTDE RFPFQASVEF 420

VFSSSPEKIK GSTPRNDPSV SVDYNTTEPA VRWDSYENFN QHHEDSVDGS LTHTRGPLDG 480

SPYAQVQRPP RQTPPAPSPE PPPPPMLSVS SDSGHSSTLT TEPAAESPGR PPPTAAERQE 540

LDRLLGGCGV ASGGRGAGRE TAILDDEEQP TVGGGPHLGV YPGHRPGLSR HCSCRQGYRE 600

PCGVPNGGYY RPEGTLERRR LAYGGYEGSP QGYAEASMEK RRLCRSLSEG LYPYPPEMGK 660

PATGDFGYRT PGYREVVILE DPGLPALYPC PACEEKLALP TAALYGLRLE REAGEGWASE 720

AGKPLLHPVR PGHPLPLLLP ACGHHHAPMP DYSCLKPPKA GEEGHEGCSY TMCPEGRYGH 780

PGYPALVTYS YGGAVPSYCP AYGRVPHSCG SPGEGRGYPS PGAHSPRAGS ISPGSPPYPQ 840

SRKLSYEIPT EEGGDRYPLP GHLASAGPLA SAESLEPVSW REGPSGHSTL PRSPRDAPCS 900

ASSELSGPST PLHTSSPVQG KESTRRQDTR SPTSAPTQRL SPGEALPPVS QAGTGKAPEL 960

PSGSGPEPPV PSPVSPTFPP SSPSDWPQER SPGGHSDGAS PRSPVPTTLP GLRHAPWQGP 1020

RGPPDSPDGS PLTPVPSQMP WLVASPEPPQ SSPTPAFPLA ASYDTNGLSQ PPLPEKRHLP 1080

GPGQQPGPWG PEQASSPARG ISHHVTFAPL LSDNVPQTPE PPTQESQSNV KFVQDTSKFW 1140

YKPHLSRDQA IALLKDKDPG AFLIRDSHSF QGAYGLALKV ATPPPSAQPW KGDPVEQLVR 1200

HFLIETGPKG VKIKGCPSEP YFGSLSALVS QHSISPISLP CCLRIPSKDP LEETPEAPVP 1260

TNMSTAADLL RQGAACSVLY LTSVETESLT GPQAVARASS AALSCSPRPT PAVVHFKVSA 1320

QGITLTDNQR KLFFRRHYPV NSITFSSTDP EDRRWTNPDG TTSKIFGFVA KKPGSPWENV 1380

CHLFAELDPD QPAGAIVTFI TKVLLGQRK 1409

Nucleotide Sequence
(FASTA)

ATGAAGTCCA GCGGCCCTGT GGAGAGGCTG CTCAGAGCCC TGGGGAGGAG GGACAGCAGC 60

CGGGCCACAA GCAGGCCTAG GAAAGCTGAG CCTCATAGCT TCCGGGAGAA GGTTTTCCGG 120

AAGAAACCTC CAGTCTGTGC AGTATGTAAG GTGACCATCG ATGGGACAGG CATTTCGTGC 180

AGAGTCTGCA AGGTGGCGAC GCACAGAAAA TGTGAAGCAA AGGTGACTTC AGCCTGTCAG 240

GCCTTGCCTC CCGTGGAGTT GCGGCGAAAC ACGGCCCCAG TCAGGCGCAT AGAGCACCTG 300

GGATCCACCA AATCTCTGAA CCACTCAAAG CAGCGCAGCA CTCTGCCCAG GAGCTTCAGC 360

CTGGACCCGC TCATGGAGCG GCGCTGGGAC TTAGACCTCA CCTACGTGAC GGAGCGCATC 420

TTGGCCGCCG CCTTCCCTGC GCGGCCCGAT GAACAGCGGC ACCGGGGCCA CCTGCGCGAG 480

CTGGCCCATG TGCTGCAATC CAAGCACCGG GACAAGTACC TGCTCTTCAA CCTTTCAGAG 540

AAAAGGCATG ACCTGACCCG CTTAAACCCC AAGGTTCAAG ACTTCGGCTG GCCTGAGCTG 600

CATGCTCCAC CCCTGGACAA GCTGTGCTCC ATCTGCAAAG CCATGGAGAC ATGGCTCAGT 660

GCTGACCCAC AGCACGTGGT TGTACTATAC TGCAAGGGAA ACAAGGGCAA GCTCGGGGTC 720

ATCGTTTCTG CCTACATGCA CTACAGCAAG ATCTCTGCAG GGGCGGACCA GGCACTGGCC 780

ACTCTTACCA TGCGGAAATT CTGCGAGGAC AAGGTGGCCA CAGAACTGCA GCCCTCCCAG 840

CGTCGATACA TCAGCTACTT CAGTGGGCTG CTATCTGGCT CCATCAGAAT GAACAGCAGC 900

CCTCTCTTCC TGCACTATGT GCTCATCCCC ATGCTGCCAG CCTTTGAACC TGGCACAGGC 960

TTCCAGCCCT TCCTTAAAAT CTACCAGTCC ATGCAGCTTG TCTACACATC TGGAGTCTAT 1020

CACATTGCAG GCCCTGGTCC CCAGCAGCTT TGCATCAGCC TGGAGCCAGC CCTCCTCCTC 1080

AAAGGCGATG TCATGGTAAC ATGTTATCAC AAGGGTGGCC GGGGCACAGA CCGGACCCTC 1140

GTGTTCCGAG TCCAATTCCA CACCTGCACC ATCCACGGAC CACAGCTCAC TTTCCCCAAG 1200

GACCAGCTGG ACGAGGCCTG GACTGATGAG AGGTTCCCCT TCCAAGCCTC TGTGGAGTTT 1260

GTCTTCTCCT CCAGCCCCGA GAAGATCAAA GGCAGCACTC CACGGAACGA CCCCTCGGTC 1320

TCTGTCGACT ACAACACCAC TGAGCCAGCC GTGCGCTGGG ACTCCTATGA GAACTTCAAC 1380

CAGCACCACG AGGACAGTGT GGATGGCTCC TTGACCCACA CCCGGGGTCC CCTGGATGGC 1440

AGTCCTTATG CCCAGGTGCA GCGGCCTCCC CGGCAGACCC CCCCGGCTCC CTCTCCAGAG 1500

CCTCCACCAC CCCCCATGCT CTCTGTCAGC AGCGACTCAG GCCATTCCTC CACACTGACC 1560

ACAGAGCCGG CTGCTGAGTC CCCTGGCCGG CCGCCCCCTA CAGCTGCTGA ACGGCAGGAG 1620

CTGGATCGCC TCCTAGGAGG CTGCGGAGTG GCCAGTGGGG GCCGGGGAGC TGGGCGCGAG 1680

ACGGCCATCC TAGATGACGA AGAGCAACCC ACTGTGGGCG GAGGCCCCCA CCTCGGAGTG 1740

TATCCAGGCC ACAGGCCTGG CCTCAGCCGC CACTGCTCCT GCCGCCAGGG CTACCGGGAG 1800

CCCTGCGGGG TTCCCAATGG GGGCTACTAC CGGCCAGAGG GAACCCTGGA GAGGAGGCGA 1860

CTGGCCTACG GGGGCTATGA GGGATCCCCC CAGGGCTACG CCGAGGCCTC GATGGAGAAG 1920

AGGCGCCTCT GCCGATCGCT GTCAGAGGGG CTATACCCCT ATCCACCTGA GATGGGGAAA 1980

CCAGCCACTG GGGACTTTGG CTACCGCACC CCAGGCTACC GGGAGGTGGT CATCCTGGAG 2040

GACCCTGGGC TGCCTGCCCT ATACCCATGC CCAGCCTGTG AGGAGAAGCT GGCGCTGCCT 2100

ACAGCAGCCT TGTATGGACT GCGGCTGGAG AGGGAGGCTG GAGAAGGGTG GGCAAGTGAG 2160

GCTGGCAAGC CTCTCCTGCA CCCAGTGCGG CCTGGGCACC CGCTGCCTCT GCTCTTGCCT 2220

GCCTGTGGGC ATCACCATGC CCCGATGCCT GACTACAGCT GCCTGAAGCC ACCCAAGGCA 2280

GGCGAGGAAG GGCACGAGGG CTGCTCCTAC ACCATGTGCC CCGAAGGCAG GTATGGGCAT 2340

CCAGGGTACC CTGCCCTGGT GACATACAGC TATGGAGGAG CAGTTCCCAG TTACTGCCCA 2400

GCATATGGCC GCGTGCCTCA TAGCTGTGGC TCTCCAGGAG AGGGCAGAGG GTATCCCAGC 2460

CCTGGTGCCC ACTCCCCACG GGCTGGCTCC ATTTCCCCGG GCAGCCCGCC CTATCCACAA 2520

TCTAGGAAGC TGAGCTACGA GATCCCTACG GAGGAGGGAG GGGACAGGTA CCCATTGCCT 2580

GGGCACCTGG CCTCAGCAGG ACCCTTGGCA TCTGCAGAGT CGCTGGAGCC GGTGTCCTGG 2640

AGGGAGGGCC CCAGTGGGCA CAGCACACTG CCTCGGTCTC CCCGAGATGC CCCATGCAGT 2700

GCTTCGTCAG AGTTGTCTGG TCCCTCCACG CCCCTGCACA CCAGCAGTCC AGTCCAGGGC 2760

AAGGAAAGCA CCCGGCGACA GGACACCAGG TCCCCCACCT CAGCGCCCAC TCAGAGACTG 2820

AGTCCTGGCG AGGCCTTGCC CCCTGTTTCC CAGGCAGGCA CCGGAAAGGC CCCTGAGCTA 2880

CCGTCGGGAA GTGGGCCTGA GCCTCCGGTC CCTAGCCCAG TCTCTCCGAC CTTCCCTCCC 2940

AGCTCGCCCA GTGACTGGCC TCAGGAAAGG AGTCCAGGGG GCCACTCAGA TGGTGCCAGT 3000

CCTCGGAGCC CTGTGCCCAC CACACTTCCT GGCCTCCGCC ACGCCCCCTG GCAAGGCCCT 3060

CGAGGCCCCC CAGACAGCCC AGATGGGTCT CCCCTCACTC CTGTGCCTTC CCAGATGCCC 3120

TGGCTTGTGG CCAGCCCAGA GCCGCCTCAG AGCTCACCTA CACCTGCTTT CCCCCTGGCT 3180

GCCTCCTATG ACACCAATGG CCTTAGCCAG CCCCCACTTC CTGAGAAACG CCACCTGCCC 3240

GGGCCGGGGC AACAGCCAGG ACCCTGGGGC CCAGAGCAGG CATCATCGCC AGCCAGAGGC 3300

ATCAGTCACC ATGTCACCTT CGCACCTCTG CTCTCAGATA ATGTCCCCCA AACCCCAGAG 3360

CCTCCTACAC AAGAGAGCCA AAGCAATGTC AAGTTTGTCC AGGATACATC CAAGTTCTGG 3420

TACAAGCCAC ACCTGTCCCG TGACCAAGCC ATTGCCCTGC TGAAGGACAA GGACCCTGGG 3480

GCCTTCCTGA TCAGGGACAG TCATTCATTC CAAGGAGCTT ATGGGCTGGC CCTCAAGGTG 3540

GCCACACCGC CACCCAGTGC CCAGCCCTGG AAAGGGGACC CCGTGGAACA GCTGGTCCGC 3600

CATTTCCTCA TTGAGACTGG GCCCAAAGGG GTGAAGATCA AGGGCTGCCC CAGTGAGCCC 3660

TACTTTGGCA GCCTGTCCGC CTTGGTCTCC CAGCACTCCA TCTCCCCCAT CTCCCTGCCC 3720

TGCTGCCTGC GCATTCCCAG CAAAGATCCT CTGGAAGAGA CCCCAGAGGC TCCAGTGCCC 3780

ACCAACATGA GCACAGCGGC AGACCTCCTG CGTCAGGGTG CTGCCTGCAG CGTGCTCTAC 3840

TTGACCTCAG TGGAGACAGA GTCACTGACG GGCCCCCAAG CTGTGGCCCG GGCCAGCTCT 3900

GCAGCTCTGA GCTGTAGCCC CCGCCCGACA CCAGCTGTTG TCCACTTCAA GGTGTCAGCC 3960

CAGGGCATTA CACTGACGGA CAACCAAAGG AAGCTCTTCT TTCGCCGCCA TTATCCAGTG 4020

AACAGCATCA CCTTCTCCAG CACTGACCCT GAAGACCGGA GATGGACCAA CCCAGACGGG 4080

ACCACCTCCA AGATCTTTGG TTTTGTGGCC AAGAAGCCGG GAAGCCCCTG GGAGAATGTG 4140

TGTCACCTCT TTGCAGAGCT TGACCCAGAT CAGCCTGCTG GCGCCATTGT CACCTTCATC 4200

ACCAAAGTTC TACTGGGCCA GAGAAAATGA 4230

Domain Profile

S: 2     rltedgfdldltyvteriiavsfPaeareevyrnnlrevvrlldskhrnkyklynlcser  61

         +l+e+++dldltyvteri+a++fPa+++e+++r++lre++++l+skhr+ky+l+nl se+

Q: 123   PLMERRWDLDLTYVTERILAAAFPARPDEQRHRGHLRELAHVLQSKHRDKYLLFNL-SEK  181

         79******************************************************.***

S: 62    rydltklnakvaefgiedlnaPaleklvsickeldeWlseddenvvvlhckggkgrlGvi  121

         r+dlt+ln+kv++fg+++l+aP+l+kl+sick++++Wls+d+++vvvl+ckg+kg+lGvi

Q: 182   RHDLTRLNPKVQDFGWPELHAPPLDKLCSICKAMETWLSADPQHVVVLYCKGNKGKLGVI  241

         ************************************************************

S: 122   vcayllaseisakadealdtfgerrtredkvagvkqPsqrryvsyfsqllkg  173

         v+ay+++s+isa+ad+al+t+++r+++edkva++ qPsqrry+syfs+ll+g

Q: 242   VSAYMHYSKISAGADQALATLTMRKFCEDKVATELQPSQRRYISYFSGLLSG  293

         *************************************************997

Domain Sequence
(FASTA)

PLMERRWDLD LTYVTERILA AAFPARPDEQ RHRGHLRELA HVLQSKHRDK YLLFNLSEKR 60

HDLTRLNPKV QDFGWPELHA PPLDKLCSIC KAMETWLSAD PQHVVVLYCK GNKGKLGVIV 120

SAYMHYSKIS AGADQALATL TMRKFCEDKV ATELQPSQRR YISYFSGLLS G 171

Keyword

Complete proteome; Metal-binding; Reference proteome; Zinc; Zinc-finger.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sus scrofa"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005622	; C:intracellular
GO:0046872	; F:metal ion binding
GO:0035556	; P:intracellular signal transduction

KEGG

InterPros

IPR008973	; C2_Ca/lipid-bd_dom_CaLB.
IPR011993	; PH_like_dom.
IPR014019	; Phosphatase_tensin-typ.
IPR002219	; Prot_Kinase_C-like_PE/DAG-bd.
IPR013625	; PTB.
IPR006020	; PTyr_interaction_dom.
IPR000980	; SH2.
IPR014020	; Tensin_phosphatase_C2-dom.

Pfam

PF08416	; PTB; 1.
PF10409	; PTEN_C2; 1.
PF00017	; SH2; 1.

SMARTs

SM00109	; C1; 1.
SM00462	; PTB; 1.
SM00252	; SH2; 1.

Prosites

PS51182	; C2_TENSIN; 1.
PS51181	; PPASE_TENSIN; 1.
PS50001	; SH2; 1.
PS00479	; ZF_DAG_PE_1; 1.
PS50081	; ZF_DAG_PE_2; 1.

Prints

Created Date

20-Feb-2013