EKS-GOG-00200

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-GOG-00200

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/RCK	462.2	8.0E-139	4	290	287

Status

Unreviewed

Ensembl Protein

ENSGGOP00000022266

UniProt Accession

G3S2G8;

Protein Name

Protein Synonyms/Alias

Gene Name

MAK

Gene Synonyms/Alias

MAK;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSGGOG00000015249	ENSGGOP00000014880	ENSGGOT00000015304
ENSGGOG00000015249	ENSGGOP00000022266	ENSGGOT00000033859

Organism

Gorilla gorilla

Functional Description

Protein Length

629

Protein Sequence
(FASTA)

MNRYTTMRQL GDGTYGSVLM GKSNESGELV AIKRMKRKFY SWDECMNLRE VKSLKKLNHA 60

NVIKLKEVIR ENDHLYFIFE YMKENLYQLM KDRLTSILPA FKVRNVQQQT LKYLEIIFRI 120

YHQGFFHRDM KPENLLCMGP ELVKIADFGL ARELRSQPPY TDYVSTRWYR APEVLLRSSV 180

YSSPIDVWAV GSIMAELYML RPLFPGTSEV DEIFKICQVL GTPRKKQSDW PEGYQLASSM 240

NFRFPQCVPI NLKTLIPNAS NEAIQLMTEM LNWDPKKRPT ASQALKHPYF QVGQVLGPSS 300

NHLESKQSLN KQLQPLESKP SLVEVEPKPL PDIIDQAVGQ PQPKTSQQPL QPIQPPQNLS 360

VQQPPKQQSQ EKPPQTLFPS IVKNMPTKPN GTLSHKSGRR RWGQTIFKSG DSWEELEDYD 420

FGASHSKKPS MGVFKEKRKK DSPFRFPEPV PSGSNHSTGE NKSLPAVTSL KSDSELSTAP 480

TSKQYYLKQS RYLPGVNPKK VSLIASGKEI NPHTWSNQLF PKSLGPVGAE LAFKRSNAGN 540

LGSYAAYNQS GYIPSFLKKE VQSAGQRIHL APLNATASEY TWNTKTGRGQ FSGRTYNPTA 600

KNLNIVNRAQ PIPSVHGRTD WVAKYGGHR 629

Nucleotide Sequence
(FASTA)

ATGAACCGAT ACACAACCAT GAGACAGTTG GGGGATGGCA CGTATGGGAG TGTGCTTATG 60

GGCAAGAGTA ATGAATCCGG GGAGCTGGTG GCCATCAAAA GGATGAAGAG AAAGTTCTAT 120

TCTTGGGATG AATGCATGAA CTTGAGAGAA GTTAAGTCTC TGAAGAAACT TAATCATGCC 180

AATGTTATTA AATTGAAAGA AGTTATCAGA GAAAATGACC ATCTTTATTT TATATTTGAA 240

TATATGAAAG AAAACCTTTA TCAATTAATG AAAGACAGAT TAACATCCAT TTTGCCTGCT 300

TTTAAAGTGA GAAATGTTCA ACAACAAACT CTGAAATACT TAGAAATAAT TTTCCGAATA 360

TATCATCAAG GCTTTTTTCA TAGGGACATG AAACCAGAAA ACTTGCTTTG TATGGGTCCA 420

GAGCTTGTGA AAATTGCTGA TTTTGGACTT GCAAGAGAAT TAAGGTCACA GCCACCATAC 480

ACTGATTATG TCTCTACCAG ATGGTATCGT GCCCCTGAAG TTTTACTGAG ATCTTCAGTT 540

TATAGTTCTC CCATTGATGT GTGGGCTGTT GGAAGTATCA TGGCTGAACT CTATATGTTA 600

AGGCCACTTT TCCCAGGGAC AAGTGAGGTC GATGAAATCT TTAAAATTTG CCAAGTTTTA 660

GGGACTCCCA GAAAAAAACA GAGTGACTGG CCAGAAGGAT ACCAGCTGGC ATCCTCTATG 720

AACTTCCGTT TTCCCCAGTG TGTTCCTATA AACTTAAAAA CTCTTATTCC CAATGCCAGT 780

AATGAAGCTA TTCAGCTCAT GACCGAAATG TTGAATTGGG ATCCAAAGAA ACGACCAACA 840

GCAAGCCAGG CATTGAAACA CCCATATTTT CAAGTTGGTC AGGTATTAGG CCCTTCGTCA 900

AATCATCTGG AATCAAAACA GTCTTTAAAT AAGCAGCTGC AACCATTAGA ATCAAAGCCA 960

TCTTTAGTTG AGGTAGAGCC TAAGCCTCTG CCGGATATAA TCGATCAGGC TGTTGGACAA 1020

CCCCAGCCAA AAACTAGCCA GCAGCCACTG CAGCCCATTC AGCCGCCACA GAACCTGAGC 1080

GTCCAGCAAC CTCCAAAGCA ACAGAGTCAG GAGAAACCGC CACAAACGCT ATTCCCGAGC 1140

ATCGTCAAAA ACATGCCAAC TAAGCCAAAT GGCACACTGA GTCATAAAAG TGGTAGGAGG 1200

CGTTGGGGTC AGACTATCTT CAAGTCTGGA GATAGCTGGG AAGAGTTGGA GGACTATGAT 1260

TTCGGAGCCT CCCATTCCAA GAAGCCAAGC ATGGGTGTTT TTAAAGAAAA AAGGAAAAAA 1320

GATTCTCCAT TTCGGTTTCC AGAGCCAGTA CCCTCAGGCT CCAACCACTC GACAGGGGAA 1380

AACAAGAGCT TACCTGCTGT TACTTCCCTA AAATCTGATT CCGAATTGTC AACTGCTCCA 1440

ACCTCTAAAC AGTACTACTT GAAACAATCA AGATATCTTC CAGGTGTGAA TCCCAAGAAG 1500

GTGTCCTTGA TAGCCAGTGG AAAGGAAATA AACCCCCACA CTTGGAGCAA CCAGTTATTC 1560

CCCAAGTCAC TGGGACCCGT CGGGGCAGAA CTTGCTTTCA AAAGGAGCAA TGCAGGAAAT 1620

CTTGGAAGTT ATGCTGCTTA CAATCAGTCA GGATATATTC CTTCCTTTCT CAAAAAAGAA 1680

GTGCAGTCAG CTGGCCAGAG GATCCACTTA GCACCTCTCA ATGCAACGGC TTCAGAATAT 1740

ACCTGGAACA CAAAAACTGG TCGGGGGCAG TTTTCAGGAC GTACTTATAA TCCTACAGCA 1800

AAAAACCTAA ATATTGTGAA CCGTGCACAG CCCATTCCCT CAGTGCACGG GAGGACAGAC 1860

TGGGTGGCCA AGTATGGAGG CCACCGGTAG 1890

Domain Profile

S: 1     yklikklGdGtfgevllakslktgelvaikkmkrkfesleevtnlrevkslkklnahdni  60

         y+++++lGdGt+g+vl++ks+++gelvaik+mkrkf+s++e++nlrevkslkkln h+n+

Q: 4     YTTMRQLGDGTYGSVLMGKSNESGELVAIKRMKRKFYSWDECMNLREVKSLKKLN-HANV  62

         99*****************************************************.****

S: 61    iklkeviidrendslylvlelmeenlyqlikdr.rkllsesklksilyqilkglafi...  116

         iklkevi  rend+ly+++e+m+enlyql+kdr   +l+  k++++  q lk l+ i

Q: 63    IKLKEVI--RENDHLYFIFEYMKENLYQLMKDRlTSILPAFKVRNVQQQTLKYLEIIfri  120

         *******..***********************835689****************986222

S: 117   hkhgffhrdlkPenilikgselvkladfGlarevrsknPytdyvstrwyraPevllrsgv  176

         +++gffhrd+kPen+l++g+elvk+adfGlare+rs++PytdyvstrwyraPevllrs+v

Q: 121   YHQGFFHRDMKPENLLCMGPELVKIADFGLARELRSQPPYTDYVSTRWYRAPEVLLRSSV  180

         569*********************************************************

S: 177   ysspldlwavGcvlaevavlrplfPGaseidqifkilevlGtPkkke..wdeayklasal  234

         yssp+d+wavG+++ae+++lrplfPG+se+d+ifki++vlGtP kk+  w+e+y+las++

Q: 181   YSSPIDVWAVGSIMAELYMLRPLFPGTSEVDEIFKICQVLGTPRKKQsdWPEGYQLASSM  240

         *******************************************987555***********

S: 235   nlkfpqvegsslktlvsnaskealellkdllaydPderataqqalkypyf  284

         n++fpq+++++lktl++nas+ea++l++++l++dP++r+ta+qalk+pyf

Q: 241   NFRFPQCVPINLKTLIPNASNEAIQLMTEMLNWDPKKRPTASQALKHPYF  290

         *************************************************9

Domain Sequence
(FASTA)

YTTMRQLGDG TYGSVLMGKS NESGELVAIK RMKRKFYSWD ECMNLREVKS LKKLNHANVI 60

KLKEVIREND HLYFIFEYMK ENLYQLMKDR LTSILPAFKV RNVQQQTLKY LEIIFRIYHQ 120

GFFHRDMKPE NLLCMGPELV KIADFGLARE LRSQPPYTDY VSTRWYRAPE VLLRSSVYSS 180

PIDVWAVGSI MAELYMLRPL FPGTSEVDEI FKICQVLGTP RKKQSDWPEG YQLASSMNFR 240

FPQCVPINLK TLIPNASNEA IQLMTEMLNW DPKKRPTASQ ALKHPYF 287

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013