EKS-GOG-00198

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-GOG-00198

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
AGC/MAST	362.0	2.7E-108	35	312	278

Status

Unreviewed

Ensembl Protein

ENSGGOP00000016360

UniProt Accession

G3RKT0;

Protein Name

Protein Synonyms/Alias

Gene Name

MASTL

Gene Synonyms/Alias

MASTL;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSGGOG00000016767	ENSGGOP00000016360	ENSGGOT00000016825

Organism

Gorilla gorilla

Functional Description

Protein Length

881

Protein Sequence
(FASTA)

MDPTAGSKKE PGGGAATEEG VNRIAVPKPP SIEEFSIVKP ISRGAFGKVY LGQKGGKLYA 60

VKVVKKADMI NKNMTHQVQA ERDALALSKS PFIVHLYYSL QSANNVYLVM EYLIGGDVKS 120

LLHIYGYFDE EMAVKYISEV ALALDYLHRH GIIHRDLKPD NMLISNEGHI KLTDFGLSKV 180

TLNRDIDINM MDILTTPSMA KPRQDYSRTP GQVLSLISSL GFNTPIAEKN QDPANILSAC 240

LSETSQLSQG LVCPMSVDQK DTTPYSSKLL KSCLETVASN PGMPVKCLTS NLLQSRKRLA 300

TSSASSQSHT FVSSVESECH SSPKWEKDCQ ESDEALGPTM MSWNAVEKLC AKSANAIETK 360

GFNKKDLELA LSPIHNSSAL PTTGRSCVNL AKKCFSGEVS WEAVELDVNN INVDTDTSQL 420

GFRQSNQWAV DSGGISEEHL GKRSLKRNFE LVDSSPCKKI IQNKKTCVEY KHNEMTDCYT 480

NQNTGLTVEV QDLKLSVHKS QQNDCANKEN IVNSFTDKQQ TPEKLPIPMI AKNLMCELDE 540

DCEKNSKRDY LSSSFLCSDD DRASKNISMN SDSSFPGISI MESPLVSQPL DSDRSIKESS 600

FEESNIEDPL IVTPDCQEKT SPKGVENPAV QESNQKMLGP PLEVLKTLAS KRNAVAFRSF 660

NSHINASNNS EPSRMNMTSL DAMDISCAYS GSYPMAITPT QKRRSCMPHQ QTPNQIKSGT 720

PYRTPKSVRR GAAPVDDGRI LGTPDYLAPE LLLGRAHGPA VDWWALGVCL FEFLTGIPPF 780

NDETPQQVFQ NILKRDIPWP EGEEKLSDNA QSAVEILLTI DDTKRAGMKE LKRHPLFSDV 840

DWENLQHQTM PFIPQPDDET DTSYFEARNT AQHLTVSGFS L 881

Nucleotide Sequence
(FASTA)

ATGGATCCCA CCGCGGGAAG CAAGAAGGAG CCTGGAGGAG GCGCGGCGAC TGAGGAGGGC 60

GTGAATAGGA TCGCAGTGCC AAAACCGCCC TCCATTGAGG AATTCAGCAT AGTGAAGCCC 120

ATTAGCCGGG GCGCCTTCGG GAAAGTGTAT CTGGGGCAGA AAGGCGGCAA ATTGTATGCA 180

GTAAAGGTTG TTAAAAAAGC AGACATGATC AACAAAAATA TGACTCATCA GGTCCAAGCT 240

GAGAGAGATG CACTGGCACT AAGCAAAAGC CCATTCATTG TCCATTTGTA TTATTCACTG 300

CAGTCTGCAA ACAATGTCTA CTTGGTAATG GAATATCTTA TTGGGGGAGA TGTCAAGTCT 360

CTCCTACATA TATATGGTTA TTTTGATGAA GAGATGGCTG TGAAATATAT TTCTGAAGTA 420

GCACTGGCTC TAGACTACCT TCACAGACAT GGAATCATCC ACAGGGACTT GAAACCGGAC 480

AATATGCTTA TTTCTAATGA GGGTCATATT AAACTGACGG ATTTTGGCCT TTCAAAAGTT 540

ACTTTGAATA GAGACATAGA TATTAATATG ATGGATATCC TTACAACACC ATCAATGGCA 600

AAACCTAGAC AAGATTATTC AAGAACCCCA GGACAAGTGT TATCACTCAT CAGCTCGTTG 660

GGATTTAACA CACCAATTGC AGAAAAAAAT CAAGACCCTG CAAACATCCT TTCAGCCTGT 720

CTGTCTGAAA CATCACAGCT TTCTCAAGGA CTCGTATGCC CTATGTCTGT AGATCAAAAG 780

GACACTACGC CTTATTCTAG CAAATTACTA AAATCATGTC TTGAAACAGT TGCCTCCAAC 840

CCAGGAATGC CTGTGAAGTG TCTAACTTCT AATTTACTCC AGTCTAGGAA AAGGCTGGCC 900

ACATCCAGTG CCAGTAGTCA ATCCCACACC TTCGTATCCA GTGTGGAATC AGAATGCCAC 960

AGCAGTCCCA AATGGGAAAA AGATTGCCAG GAAAGTGATG AAGCATTGGG CCCAACAATG 1020

ATGAGTTGGA ATGCAGTTGA AAAGTTATGC GCAAAATCTG CAAATGCCAT TGAGACGAAA 1080

GGTTTCAATA AAAAGGATCT GGAGTTAGCT CTTTCTCCCA TTCATAACAG CAGTGCCCTT 1140

CCCACCACTG GACGCTCTTG TGTAAACCTT GCTAAAAAAT GCTTCTCTGG GGAAGTTTCT 1200

TGGGAAGCAG TAGAACTGGA CGTAAATAAT ATAAATGTGG ACACTGACAC AAGTCAGTTA 1260

GGTTTCCGTC AGTCAAATCA GTGGGCTGTG GATTCTGGTG GGATATCTGA AGAGCACCTT 1320

GGGAAAAGAA GTTTAAAAAG AAATTTTGAG TTGGTTGACT CCAGTCCTTG TAAAAAAATT 1380

ATACAGAATA AAAAAACTTG TGTAGAGTAT AAGCATAACG AAATGACAGA TTGTTATACA 1440

AATCAAAATA CAGGCTTAAC AGTTGAAGTG CAGGACCTTA AGCTATCAGT GCACAAAAGT 1500

CAACAAAATG ACTGTGCTAA TAAGGAGAAC ATTGTCAATT CTTTTACTGA TAAACAACAA 1560

ACACCAGAAA AATTACCTAT ACCAATGATA GCAAAAAACC TTATGTGTGA ACTCGATGAA 1620

GACTGTGAAA AGAATAGTAA GAGGGACTAC TTAAGTTCTA GTTTTCTATG TTCTGATGAT 1680

GATAGAGCTT CTAAAAATAT TTCTATGAAC TCTGATTCAT CTTTTCCTGG AATTTCTATA 1740

ATGGAAAGTC CATTAGTAAG TCAGCCCTTA GATTCAGATA GAAGCATCAA AGAATCCTCT 1800

TTTGAAGAAT CAAATATTGA AGATCCGCTT ATTGTAACAC CAGATTGCCA AGAAAAGACC 1860

TCACCAAAAG GTGTCGAGAA CCCTGCTGTA CAAGAGAGTA ACCAAAAAAT GTTAGGTCCT 1920

CCTTTGGAGG TGCTGAAAAC GTTAGCCTCT AAAAGAAATG CTGTTGCTTT TCGAAGTTTT 1980

AACAGTCATA TTAATGCATC CAATAACTCA GAACCATCCA GAATGAACAT GACTTCTTTA 2040

GATGCAATGG ATATTTCGTG TGCCTACAGT GGTTCATATC CCATGGCTAT AACCCCTACT 2100

CAAAAAAGAA GATCCTGTAT GCCACATCAG CAGACCCCAA ATCAGATCAA GTCGGGAACT 2160

CCATACCGAA CTCCGAAGAG TGTGAGAAGA GGGGCGGCCC CCGTTGATGA TGGGCGAATT 2220

CTAGGAACCC CAGACTACCT TGCACCCGAG CTGTTACTAG GCAGGGCCCA TGGTCCTGCG 2280

GTAGACTGGT GGGCACTTGG AGTTTGCTTG TTTGAATTTC TAACAGGAAT TCCCCCTTTC 2340

AATGATGAAA CACCACAACA AGTATTCCAG AATATTCTGA AAAGAGATAT CCCTTGGCCA 2400

GAAGGTGAAG AAAAGTTATC TGATAATGCT CAAAGTGCAG TAGAAATACT TTTAACCATT 2460

GATGATACAA AGAGAGCTGG AATGAAAGAG CTAAAACGTC ATCCTCTCTT CAGTGATGTG 2520

GACTGGGAAA ATCTGCAGCA TCAGACTATG CCTTTCATCC CCCAGCCAGA TGATGAAACA 2580

GATACCTCCT ATTTTGAAGC CAGGAATACT GCTCAGCACC TGACCGTATC TGGATTTAGT 2640

CTGTAG 2646

Domain Profile

S: 1     feiiklisrGayGavylvrhketrkrfavkkikkqdlilknqvqqvfaerdilalaenpf  60

         f+i+k+isrGa+G+vyl  +++++k++avk++kk+d+i+kn+++qv+aerd+lal+++pf

Q: 35    FSIVKPISRGAFGKVYL--GQKGGKLYAVKVVKKADMINKNMTHQVQAERDALALSKSPF  92

         89***************..*****************************************

S: 61    vvslyysletrrnlylvmeyveGGdvksllkniGaldvemarlyiaevvlaleylhryGi  120

         +v+lyysl++++n+ylvmey++GGdvksll+++G++d+ema++yi+ev+lal+ylhr+Gi

Q: 93    IVHLYYSLQSANNVYLVMEYLIGGDVKSLLHIYGYFDEEMAVKYISEVALALDYLHRHGI  152

         ************************************************************

S: 121   vhrdlkPdnllitseGhikltdfGlskvglmslttnlyegyidkdarefldkqvcgtPey  180

         +hrdlkPdn+li++eGhikltdfGlskv+l+          id++++++l     +tP++

Q: 153   IHRDLKPDNMLISNEGHIKLTDFGLSKVTLN--------RDIDINMMDIL-----TTPSM  199

         *******************************........67999999999.....*****

S: 181   iaPevilrqgygkpvdwwalgiilyeflvgivpffgdtpeelfaqv.....lsdeivwP.  234

         ++P    rq+y++++++++++i++++f+++i+++++d+++ l+a++     ls+++v+P

Q: 200   AKP----RQDYSRTPGQVLSLISSLGFNTPIAEKNQDPANILSACLsetsqLSQGLVCPm  255

         ***....*************************************9999999*********

S: 235   ...ekde.alssealelisellesnP..............rerlgtgsaaevkqhefl  274

            +kd+ ++ss++l+++ e+++snP              r+rl+t s+a++++h+f+

Q: 256   svdQKDTtPYSSKLLKSCLETVASNPgmpvkcltsnllqsRKRLAT-SSASSQSHTFV  312

         **9899889*************************************.88899***996

Domain Sequence
(FASTA)

FSIVKPISRG AFGKVYLGQK GGKLYAVKVV KKADMINKNM THQVQAERDA LALSKSPFIV 60

HLYYSLQSAN NVYLVMEYLI GGDVKSLLHI YGYFDEEMAV KYISEVALAL DYLHRHGIIH 120

RDLKPDNMLI SNEGHIKLTD FGLSKVTLNR DIDINMMDIL TTPSMAKPRQ DYSRTPGQVL 180

SLISSLGFNT PIAEKNQDPA NILSACLSET SQLSQGLVCP MSVDQKDTTP YSSKLLKSCL 240

ETVASNPGMP VKCLTSNLLQ SRKRLATSSA SSQSHTFV 278

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>