EKS-GOG-00416

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-GOG-00416

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
AGC/SGK	534.8	5.6E-161	132	389	258

Status

Unreviewed

Ensembl Protein

ENSGGOP00000016460

UniProt Accession

G3SAI6;

Protein Name

Protein Synonyms/Alias

Gene Name

SGK3

Gene Synonyms/Alias

SGK3;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSGGOG00000016867	ENSGGOP00000025109	ENSGGOT00000023504
ENSGGOG00000016867	ENSGGOP00000016460	ENSGGOT00000016925

Organism

Gorilla gorilla

Functional Description

Protein Length

466

Protein Sequence
(FASTA)

MQRDHTMDYK ESCPSVSIPS SDEHREKKKR FTVYKVLVSV GRSEWFVFRR YAEFDKLYNT 60

LKKQFPAMAL KIPAKRIFGD NFDPDFIKQR RAGLNEFIQN LVRYPELYNL HSTSQNINLG 120

PSGNPHAKPT DFDFLKVIGK GSFGKVLLAK RKLDGKFYAV KVLQKKIVLN RKEQKHIMAE 180

RNVLLKNVKH PFLVGLHYSF QTTEKLYFVL DFVNGGELFF HLQRERSFPE HRARFYAAEI 240

ASALGYLHSI KIVYRDLKPE NILLDSVGHV VLTDFGLCKE GIAISDTTTT FCGTPEYLAP 300

EVIRKQPYDN TVDWWCLGAV LYEMLYGLPP FYCRDVAEMY DNILHKPLSL RPGVSLTAWS 360

ILEELLEKDR QNRLGAKEDF LEIQNHPFFE SLSWADLVQK KIPPPFNPNV AGPDDIRNFD 420

TAFTEETVPY SVCVSSDYSI VNASVLEADD AFVGFSYAPP SEDLFL 466

Nucleotide Sequence
(FASTA)

ATGCAAAGAG ATCACACCAT GGACTACAAG GAAAGCTGCC CAAGTGTAAG CATTCCCAGC 60

TCCGATGAAC ACAGAGAGAA AAAGAAGAGA TTTACTGTTT ATAAAGTTCT GGTTTCAGTG 120

GGAAGAAGTG AATGGTTTGT CTTCAGGAGA TATGCAGAGT TTGATAAACT TTATAACACT 180

TTAAAAAAAC AGTTTCCTGC TATGGCCCTG AAGATTCCTG CCAAGAGAAT ATTTGGTGAT 240

AATTTTGATC CAGATTTTAT TAAACAAAGA CGAGCAGGAC TAAACGAATT CATTCAGAAC 300

CTAGTTAGGT ATCCAGAACT TTATAACCTA CACTCTACCT CACAGAACAT CAACCTGGGA 360

CCGTCTGGAA ATCCTCATGC CAAACCAACT GACTTTGATT TCTTAAAAGT TATTGGAAAA 420

GGCAGCTTTG GCAAGGTTCT TCTTGCAAAA CGGAAACTGG ATGGAAAATT TTATGCTGTC 480

AAAGTGTTAC AGAAAAAAAT AGTTCTCAAC AGAAAAGAGC AAAAACATAT TATGGCTGAA 540

CGTAATGTGC TCTTGAAAAA TGTGAAACAT CCATTTTTGG TTGGATTGCA TTATTCCTTC 600

CAAACAACTG AAAAGCTTTA TTTTGTTCTG GATTTTGTTA ATGGAGGGGA GCTTTTTTTC 660

CACTTACAAA GAGAACGGTC CTTTCCTGAG CACAGAGCTA GGTTTTACGC TGCTGAAATT 720

GCTAGTGCAT TGGGTTACTT ACATTCCATC AAAATAGTAT ACAGAGACTT GAAACCAGAA 780

AATATTCTTT TGGATTCAGT AGGACATGTT GTCTTAACAG ATTTTGGGCT TTGTAAAGAA 840

GGAATTGCTA TTTCTGACAC CACTACTACA TTTTGTGGGA CACCAGAGTA TCTTGCACCT 900

GAAGTAATTA GAAAACAGCC CTATGACAAT ACTGTAGATT GGTGGTGCCT TGGGGCTGTT 960

CTGTATGAAA TGCTGTATGG ATTGCCTCCT TTTTATTGCC GAGATGTTGC TGAAATGTAT 1020

GATAATATCC TTCACAAACC CCTAAGTTTG AGGCCAGGAG TGAGTCTTAC AGCCTGGTCC 1080

ATTCTGGAAG AACTCCTAGA AAAAGACAGG CAAAATCGAC TTGGTGCCAA GGAAGACTTT 1140

CTTGAAATTC AGAATCATCC TTTTTTTGAA TCACTCAGCT GGGCTGACCT TGTACAAAAG 1200

AAGATTCCAC CACCATTTAA TCCTAATGTG GCTGGACCAG ATGATATCAG AAACTTTGAC 1260

ACAGCATTTA CAGAAGAAAC AGTTCCATAT TCTGTGTGTG TATCTTCTGA CTATTCTATA 1320

GTGAATGCCA GTGTATTGGA GGCAGATGAT GCATTCGTTG GTTTCTCTTA TGCACCTCCT 1380

TCAGAAGACT TATTTTTGTG A 1401

Domain Profile

S: 1     fdflkvigkgsfgkvllakrkadekfyavkvlqkkailkkkeekhimaernvllknvkhp  60

         fdflkvigkgsfgkvllakrk d+kfyavkvlqkk++l++ke+khimaernvllknvkhp

Q: 132   FDFLKVIGKGSFGKVLLAKRKLDGKFYAVKVLQKKIVLNRKEQKHIMAERNVLLKNVKHP  191

         9***********************************************************

S: 61    flvglhysfqtaeklyfvldyvnggelffhlqrersfleprarfyaaeiasalgylhsln  120

         flvglhysfqt+eklyfvld+vnggelffhlqrersf+e+rarfyaaeiasalgylhs++

Q: 192   FLVGLHYSFQTTEKLYFVLDFVNGGELFFHLQRERSFPEHRARFYAAEIASALGYLHSIK  251

         ************************************************************

S: 121   ivyrdlkpenilldskghvvltdfglckeeieaedttstfcgtpeylapevlrkkpydrt  180

         ivyrdlkpenillds ghvvltdfglcke+i+++dtt+tfcgtpeylapev+rk+pyd+t

Q: 252   IVYRDLKPENILLDSVGHVVLTDFGLCKEGIAISDTTTTFCGTPEYLAPEVIRKQPYDNT  311

         ************************************************************

S: 181   vdwwclgavlyemlyglppfysrdvaemydnilnkplqlkpgisvaalelleellekdrk  240

         vdwwclgavlyemlyglppfy+rdvaemydnil+kpl+l+pg+s++a+++leellekdr+

Q: 312   VDWWCLGAVLYEMLYGLPPFYCRDVAEMYDNILHKPLSLRPGVSLTAWSILEELLEKDRQ  371

         ************************************************************

S: 241   krlgakedfleiknhvff  258

         +rlgakedflei+nh+ff

Q: 372   NRLGAKEDFLEIQNHPFF  389

         *****************9

Domain Sequence
(FASTA)

FDFLKVIGKG SFGKVLLAKR KLDGKFYAVK VLQKKIVLNR KEQKHIMAER NVLLKNVKHP 60

FLVGLHYSFQ TTEKLYFVLD FVNGGELFFH LQRERSFPEH RARFYAAEIA SALGYLHSIK 120

IVYRDLKPEN ILLDSVGHVV LTDFGLCKEG IAISDTTTTF CGTPEYLAPE VIRKQPYDNT 180

VDWWCLGAVL YEMLYGLPPF YCRDVAEMYD NILHKPLSLR PGVSLTAWSI LEELLEKDRQ 240

NRLGAKEDFL EIQNHPFF 258

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0035091	; F:phosphatidylinositol binding
GO:0004674	; F:protein serine/threonine kinase activity
GO:0007154	; P:cell communication

KEGG

InterPros

IPR000961	; AGC-kinase_C.
IPR011009	; Kinase-like_dom.
IPR001683	; Phox.
IPR017892	; Pkinase_C.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069	; Pkinase; 1.
PF00433	; Pkinase_C; 1.
PF00787	; PX; 1.

SMARTs

SM00312	; PX; 1.
SM00133	; S_TK_X; 1.
SM00220	; S_TKc; 1.

Prosites

PS51285	; AGC_KINASE_CTER; 1.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.
PS50195	; PX; 1.

Prints

Created Date

20-Feb-2013