EKS-GOG-00073

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-GOG-00073

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDK	197.2	4.4E-58	13	175	163

Status

Unreviewed

Ensembl Protein

ENSGGOP00000025164

UniProt Accession

G3SAP1;

Protein Name

Protein Synonyms/Alias

Gene Name

CDK6

Gene Synonyms/Alias

CDK6;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSGGOG00000025851	ENSGGOP00000025164	ENSGGOT00000026266

Organism

Gorilla gorilla

Functional Description

Protein Length

289

Protein Sequence
(FASTA)

MEKDGLCRAD QQYECVAEIG EGAYGKVFKA RDLKNGGRFV ALKRVRVQTG EEGMPLSTIR 60

EVAVLRHLET FEHPNVVRLF DVCTVSRTDR ETKLTLVFEH VDQDLTTYLD KVPEPGVPTE 120

TIKDMMFQLL RGLDFLHSHR VVHRDLKPQN ILVTSSGQIK LADFGLARIY SFQMALTSVP 180

LFRGSSDVDQ LGKILDVIGL PGEEDWPRDV ALPRQAFHSK SAQPIEKFVT DIDELGKDLL 240

LKCLTFNPAK RISAYSALSH PYFQDLERCK ENLDSHLPPS QNTSELNTA 289

Nucleotide Sequence
(FASTA)

ATGGAGAAGG ACGGCCTGTG CCGCGCTGAC CAGCAGTACG AATGCGTGGC GGAGATCGGG 60

GAGGGCGCCT ATGGGAAGGT GTTCAAGGCC CGCGACTTGA AGAACGGAGG CCGTTTCGTG 120

GCGTTGAAGC GCGTGCGGGT GCAGACCGGC GAGGAGGGCA TGCCGCTCTC CACCATCCGC 180

GAGGTGGCGG TGCTGAGGCA CCTGGAGACC TTCGAGCACC CCAACGTGGT CAGGTTGTTT 240

GATGTGTGCA CAGTGTCACG AACAGACAGA GAAACCAAAC TAACTTTAGT GTTTGAACAT 300

GTCGATCAAG ACTTGACCAC TTACTTGGAT AAAGTTCCAG AGCCTGGAGT GCCCACTGAA 360

ACCATAAAGG ATATGATGTT TCAGCTTCTC CGAGGTCTGG ACTTTCTTCA TTCACACCGA 420

GTAGTGCATC GCGATCTAAA ACCACAGAAC ATTCTGGTGA CCAGCAGCGG ACAAATAAAA 480

CTCGCTGACT TCGGCCTTGC CCGCATCTAT AGTTTCCAGA TGGCTCTAAC CTCAGTGCCT 540

CTTTTTCGTG GAAGTTCAGA TGTTGATCAA CTAGGAAAAA TCTTGGACGT AATTGGACTC 600

CCAGGAGAAG AAGACTGGCC TAGAGATGTT GCCCTTCCCA GGCAGGCTTT TCATTCAAAA 660

TCTGCCCAAC CAATTGAGAA GTTTGTAACA GATATCGATG AACTAGGCAA AGACCTACTT 720

CTGAAGTGTT TGACATTTAA CCCAGCCAAA AGAATATCTG CCTACAGTGC CCTGTCTCAC 780

CCATACTTCC AGGACCTGGA AAGGTGCAAA GAAAACCTGG ATTCCCACCT GCCGCCCAGC 840

CAGAACACCT CGGAGCTGAA TACAGCCTGA 870

Domain Profile

S: 1     yeklekigeGtygkvykakd.ketgevvAlKkirlekekegvpitalrEisllkel...k  56

         ye++++igeG+ygkv+ka+d k+ g++vAlK++r+++ +eg+p +++rE+++l++l   +

Q: 13    YECVAEIGEGAYGKVFKARDlKNGGRFVALKRVRVQTGEEGMPLSTIREVAVLRHLetfE  72

         899*****************888999*****************************98889

S: 57    hknivkLlevva....kdkkklyLvfefleqdLkkllkkkkkkklsleevkslllqlleg  112

         h+n+v+L +v++     +++kl+Lvfe+++qdL+++l+k ++ ++++e++k +++qll+g

Q: 73    HPNVVRLFDVCTvsrtDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTETIKDMMFQLLRG  132

         ************99855569****************************************

S: 113   laylHsnkilHRDlKpqNlLiskegklklaDfGlarafssplk  155

         l++lHs++++HRDlKpqN+L++++g++klaDfGlar +s ++

Q: 133   LDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQMA  175

         **************************************98875

Domain Sequence
(FASTA)

YECVAEIGEG AYGKVFKARD LKNGGRFVAL KRVRVQTGEE GMPLSTIREV AVLRHLETFE 60

HPNVVRLFDV CTVSRTDRET KLTLVFEHVD QDLTTYLDKV PEPGVPTETI KDMMFQLLRG 120

LDFLHSHRVV HRDLKPQNIL VTSSGQIKLA DFGLARIYSF QMA 163

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Homo sapiens"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Rattus norvegicus"; ?>Sorex araneus"; ?>Taeniopygia guttata"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>