EKS-GAM-00270

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-GAM-00270

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/MAPK	409.3	8.2E-123	41	336	296

Status

Unreviewed

Ensembl Protein

ENSGMOP00000004185

UniProt Accession

D7R9Z8;

Protein Name

Protein Synonyms/Alias

Mitogen-activated protein kinase 8;

Gene Name

D7R9Z8_GADMO

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSGMOG00000003943	ENSGMOP00000004185	ENSGMOT00000004314

Organism

Gadus morhua

Functional Description

Protein Length

452

Protein Sequence
(FASTA)

RNLLDAQKAL IEDFTMNKNK REKEFYSIDV GDSTFTVLRR YQNLRPIGSG AQGIVCSAYD 60

QNLERNVAIK KLSRPFQNQT HAKRAYRELV LMKCVNHKNI IGLLHVFTPQ KTLEDFQDVY 120

LVMELMDANL CQVIQMELDH ERLSYLLYQM LCGIKHLHAA GIIHRDLKPS NIVVKSDCTL 180

KILDFGLART AATGLLMTPY VVTRYYRAPE VILGMGYQAN VDIWSVGCIL AEMVRHKILF 240

PGRDYIDQWN KVIEQLGTPT QEFLMKLNQS VRTYVENRPR YAGYSFEKLF PDVLFPADSE 300

HNKLKASQAR DLLSKMLVID ASKRISVDEA LKHPYINVWY DPAEVEAPPP KFTDKQLEER 360

EHTVDEWKDL IYKEVYDWEE CTKNGVIRGQ PPPLGAAVID SSPQPASSSS SANDVSSMST 420

DPSDPSSDPT MTSDTESSLD SHTSLGALGC CR 452

Nucleotide Sequence
(FASTA)

AGGAATCTTT TGGATGCACA GAAAGCATTA ATAGAAGATT TCACCATGAA CAAAAACAAG 60

AGAGAAAAAG AGTTCTACAG CATAGATGTT GGGGATTCAA CGTTTACAGT TCTGAGGCGG 120

TATCAGAACC TCCGACCGAT CGGGTCTGGA GCGCAGGGTA TTGTGTGCTC TGCATACGAT 180

CAAAACCTTG AACGAAATGT TGCCATCAAG AAGCTGAGCC GGCCCTTCCA GAACCAGACG 240

CACGCCAAGC GCGCCTACAG AGAACTAGTT CTAATGAAAT GTGTCAATCA CAAAAATATC 300

ATCGGTTTAT TACATGTATT CACTCCACAA AAAACATTAG AAGACTTCCA AGATGTGTAC 360

CTGGTGATGG AGCTGATGGA TGCCAACCTG TGCCAGGTGA TCCAGATGGA GCTGGACCAC 420

GAGAGGCTGT CCTACCTGCT CTACCAGATG TTGTGTGGCA TCAAGCACCT GCACGCCGCG 480

GGCATCATTC ACAGGGATCT GAAGCCCAGC AACATCGTGG TGAAGTCCGA CTGCACTCTG 540

AAGATCCTGG ACTTCGGTCT GGCCCGGACC GCCGCCACGG GCCTCCTGAT GACCCCGTAC 600

GTGGTCACGC GCTACTACAG GGCGCCGGAG GTCATCCTGG GCATGGGCTA CCAGGCCAAC 660

GTGGACATAT GGTCTGTGGG CTGCATTCTG GCAGAAATGG TCCGCCATAA AATCCTCTTC 720

CCGGGAAGGG ACTACATTGA CCAGTGGAAC AAGGTGATCG AGCAGCTAGG CACCCCCACC 780

CAGGAGTTCC TGATGAAGCT GAACCAGTCG GTCAGGACCT ACGTGGAGAA CCGACCCCGC 840

TACGCCGGCT ACAGCTTTGA GAAGCTGTTC CCCGACGTGC TCTTCCCTGC CGACTCAGAA 900

CACAACAAAC TCAAAGCGAG CCAAGCCAGG GATCTGTTGT CCAAAATGTT AGTTATCGAC 960

GCCTCCAAGC GCATCTCTGT AGACGAAGCC CTGAAGCACC CCTACATTAA CGTTTGGTAT 1020

GATCCGGCTG AGGTGGAGGC GCCCCCTCCA AAGTTCACCG ACAAGCAGTT GGAGGAGAGA 1080

GAGCACACGG TGGACGAGTG GAAAGATCTG ATTTATAAGG AGGTTTACGA TTGGGAGGAG 1140

TGCACCAAAA ACGGGGTGAT CCGAGGCCAA CCCCCACCTT TAGGTGCAGC AGTGATTGAC 1200

AGCTCCCCAC AGCCCGCCTC CTCCTCTTCC TCAGCCAATG ACGTCTCGTC CATGTCCACG 1260

GACCCCAGTG ACCCCAGCAG TGACCCTACC ATGACCTCTG ACACAGAGAG CAGCCTGGAC 1320

AGCCATACCT CCCTAGGAGC TCTGGGCTGC TGTAGATAA 1359

Domain Profile

S: 1     yeslkplgeGaygvvvsavdkrteervaikklsrpfqketsakrtlRElkllkelkheNi  60

         y++l+p+g+Ga+g+v+sa+d++ e++vaikklsrpfq++t+akr++REl l+k+++h+Ni

Q: 41    YQNLRPIGSGAQGIVCSAYDQNLERNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNI  100

         899*********************************************************

S: 61    iklldvftpeeeleelkdvYlvtelmetdLkkviksqklsdehiklllyqilrglkylHs  120

         i ll vftp+++le+++dvYlv+elm+++L++vi+++ l++e++++llyq+l+g+k+lH+

Q: 101   IGLLHVFTPQKTLEDFQDVYLVMELMDANLCQVIQME-LDHERLSYLLYQMLCGIKHLHA  159

         ************************************9.**********************

S: 121   anviHrDlKPsNllvnedcelkildFGlarsadkekekklteyvatrwYraPeillslke  180

         a++iHrDlKPsN++v++dc+lkildFGlar+a +     +t+yv+tr+YraPe++l  +

Q: 160   AGIIHRDLKPSNIVVKSDCTLKILDFGLARTAATGL--LMTPYVVTRYYRAPEVILG-MG  216

         *******************************99995..5*****************9.99

S: 181   ytkavDiWsvGCIlaElltgkplfpgkdeidqlekilevlgtpseeflkkieseearnyi  240

         y+ +vDiWsvGCIlaE++++k+lfpg+d+idq++k++e+lgtp++efl+k+++ ++r+y+

Q: 217   YQANVDIWSVGCILAEMVRHKILFPGRDYIDQWNKVIEQLGTPTQEFLMKLNQ-SVRTYV  275

         ****************************************************9.5*****

S: 241   kslpkkkkkdfeelfpk............aseealdLleklLvldpdkRisveeaLehpY  288

         +++p+++  +fe+lfp+            + ++a+dLl+k+Lv+d++kRisv+eaL+hpY

Q: 276   ENRPRYAGYSFEKLFPDvlfpadsehnklKASQARDLLSKMLVIDASKRISVDEALKHPY  335

         *****************************99*****************************

S: 289   l  289

Q: 336   I  336

Domain Sequence
(FASTA)

YQNLRPIGSG AQGIVCSAYD QNLERNVAIK KLSRPFQNQT HAKRAYRELV LMKCVNHKNI 60

IGLLHVFTPQ KTLEDFQDVY LVMELMDANL CQVIQMELDH ERLSYLLYQM LCGIKHLHAA 120

GIIHRDLKPS NIVVKSDCTL KILDFGLART AATGLLMTPY VVTRYYRAPE VILGMGYQAN 180

VDIWSVGCIL AEMVRHKILF PGRDYIDQWN KVIEQLGTPT QEFLMKLNQS VRTYVENRPR 240

YAGYSFEKLF PDVLFPADSE HNKLKASQAR DLLSKMLVID ASKRISVDEA LKHPYI 296

Keyword

Kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Petromyzon marinus"; ?>Procavia capensis"; ?>Rattus norvegicus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xiphophorus maculatus"; ?>