EPS-GAM-00030

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-GAM-00030

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPM/PP2C	178.3	2.7E-52	1002	1250	249

Status

Unreviewed

Ensembl Protein

ENSGMOP00000012199

Gene Name

PHLPP1 (2 of 2)

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSGMOG00000011383	ENSGMOP00000012199	ENSGMOT00000012526

Organism

Gadus morhua

Protein Length

1375

Protein Sequence
(FASTA)

NPLLNRRRRK HKRNLSLGAP PTAGQPAAAS AETAATPTPS SSPLNTLSLD RKTFLRQKQS 60

KQLQVSDKAW VKADPQRGCV HVHDWLTPSY PRPVLCTTDT TAREIYTQLE EGKAGTIVRM 120

KRKTGAQVDL NGNCKATGQS DDAEVKIPKS EIEPDSMPSD PSSEVYLSDS LSLGMMQSPD 180

DRYGLYSGSD VETSSTCEDF SSCGPHGSEP CDGPGVGSDA LGPGPYADSP TEGPDPFESS 240

SDDVDLASSP TRLGSCGGGR GTIEPSSEDG PSARTLEDGG AESRPDTGLP SKCSSSSQAR 300

PLGSATPQPD LELLVQGAVW PESVDSPAPG MYMQVHGGSV WRLEDEERPL KILNEYLTNL 360

GFEDPARVQE EGMNHEIGCL IRFYFDSGKR QVILSGTCLI VSSVKHAHTG KMHILPLIGG 420

KVEEVRRHSH CLAFSSAGPQ NQTYYVSYDS YTEHLRWHRS AAKIASQRVS SVDLSCCSLE 480

ELPPALFYSQ DLTHLNLKHN FMSPHRGLGA LTRFCKLRSL TLSNNRLCEF PVALCDMSSL 540

TEINLSGNFL TSLPPAAGTM HNLQTLLLDG NCLSSLPVEL GSLEGLVYLG LSFNRFHCIP 600

PVLEKFKGLE RLCLAGNKLS LLDLSALQWL PARHVDLRLN RLQSVVVGEA GALAHVTQLD 660

VRDAGLEELD LRPLSSLELL RCDRNSLARL RVSGHALKAL HAANNELKQL EVEPVPESLT 720

ALDLSRNKLD SIPGWVIGCS RLEVLDINHN YVTELPLQFL CSSSLRKLLI GWNRLSSLAD 780

RLERCQLEVL DVQHNQLTGL PHNLFIKALS LRYLNASANK LESVPPATQS EESLSTLQEL 840

YLTNNSLTDK CVPLLAGHTH LRVLHLAFNL LQTFAASKLA GLEQLEELEL SGNRLRAVPT 900

TILSCRRLHT LAAHSNCITV FPEVLQLPEI KCVDVSCNEI TEVSLPESLP AKLQELDLTG 960

NPRLTLDHKS LELLNNIRCF RVDPSPSAPG ASEGPGVPAV WSHGYTEASG VKNKLCVAAL 1020

ALDSFCGSRE ALYGVFDGER NVEVPYLLQC TMGDVLAEEL HKSQRRENYM TNTFLTMQRK 1080

LGTAGQRLGG SAALCHIRHD PAPLGARGGC LTLTAANVGK CCAVLCRAGR ALPLSVTHSV 1140

REEEELRRVR THNAIVTEDN KVNGVTDSTR IMGYSFLCPA VTPRPHVSTV TLTPHDEFFL 1200

LGSRGLWDTL SPSEAVEAVR SVPDSLAAAK KLVTLAQSYG CPLSASAVVV QLSITDDCCG 1260

FCEPPPPPPG SPGLGTHGAR AEGALSGTLG RRPRPNGSVA CQGRSQDLIE VAADAPAKKG 1320

GYFNAPAQPD PDDQLIIPPE LEEEVRQIIQ QQQQQQANQQ AHSFQKPADY FVTPL 1375

Nucleotide Sequence
(FASTA)

AACCCTTTGC TAAACAGGAG ACGGCGAAAG CACAAGCGTA ACCTCTCCCT GGGCGCCCCG 60

CCGACCGCCG GTCAGCCCGC GGCGGCTTCG GCGGAGACGG CGGCCACACC GACTCCTTCT 120

AGCTCTCCGC TGAACACTCT CAGCCTTGAC AGAAAGACCT TCCTACGGCA GAAGCAGTCC 180

AAGCAGCTCC AGGTGTCAGA CAAGGCATGG GTGAAAGCTG ACCCACAGCG GGGTTGCGTC 240

CACGTCCACG ACTGGCTAAC CCCCTCCTAC CCGAGACCAG TGCTCTGCAC GACAGACACC 300

ACGGCTAGAG AGATCTATAC CCAACTGGAG GAAGGCAAAG CCGGGACGAT AGTGCGGATG 360

AAACGCAAAA CAGGCGCACA GGTGGACTTG AACGGAAACT GCAAAGCAAC CGGACAGAGC 420

GACGACGCAG AGGTCAAAAT CCCCAAGTCG GAGATTGAGC CCGACAGCAT GCCCAGCGAC 480

CCCTCCTCCG AGGTGTACCT CAGCGACAGC CTCAGCCTGG GCATGATGCA GAGCCCAGAC 540

GACCGCTACG GGCTGTACTC GGGTTCCGAC GTGGAGACCA GCAGCACCTG CGAGGACTTC 600

AGCTCCTGTG GGCCCCACGG AAGCGAGCCT TGCGACGGCC CGGGTGTGGG CAGCGACGCC 660

CTGGGACCCG GCCCTTATGC CGACAGCCCC ACGGAGGGTC CCGACCCGTT CGAGAGCTCT 720

TCGGACGACG TAGACCTCGC CTCGTCCCCC ACGCGCCTGG GCAGCTGCGG GGGGGGCCGG 780

GGCACCATCG AACCCAGCAG TGAAGACGGG CCGTCTGCGA GAACACTGGA GGACGGAGGA 840

GCGGAGAGCA GGCCCGACAC CGGACTTCCC TCCAAATGCA GCTCCAGCTC CCAGGCCCGG 900

CCGCTAGGCA GCGCGACTCC CCAGCCGGAC CTGGAGCTTC TGGTGCAGGG CGCCGTGTGG 960

CCCGAGTCCG TCGACAGCCC CGCCCCGGGC ATGTACATGC AGGTGCACGG GGGTTCAGTC 1020

TGGAGGCTGG AGGACGAGGA GAGGCCCCTG AAGATACTCA ATGAGTACCT CACCAACCTG 1080

GGCTTCGAGG ACCCGGCGCG CGTCCAGGAG GAGGGCATGA ACCATGAGAT TGGCTGCCTA 1140

ATACGCTTTT ACTTTGACAG CGGAAAGCGG CAGGTCATCC TGAGTGGCAC CTGCCTCATC 1200

GTCTCCTCCG TCAAGCATGC ACACACTGGC AAGATGCACA TCCTGCCTCT GATTGGTGGA 1260

AAGGTGGAGG AGGTGCGGAG ACACAGCCAC TGCCTGGCGT TCAGCTCCGC TGGTCCCCAG 1320

AACCAGACCT ACTACGTCAG TTACGACTCG TACACAGAAC ACCTCCGCTG GCACCGCAGC 1380

GCAGCCAAGA TTGCATCCCA GAGGGTGAGT TCAGTGGACC TGTCGTGCTG CAGCCTAGAG 1440

GAACTGCCCC CCGCTCTCTT CTACAGCCAG GACCTCACCC ACCTCAACCT CAAACACAAC 1500

TTCATGTCCC CTCACAGGGG CCTGGGGGCC CTCACCAGGT TCTGTAAGCT GCGTAGCTTG 1560

ACTCTGTCTA ACAACAGGCT GTGTGAGTTC CCCGTGGCGC TGTGCGACAT GTCCTCGCTG 1620

ACGGAGATCA ACCTATCGGG GAACTTCCTG ACTTCCCTGC CGCCGGCAGC CGGGACCATG 1680

CACAACCTGC AGACTCTGCT CCTGGACGGG AACTGCCTGA GCTCCCTGCC TGTGGAGCTG 1740

GGCTCCCTGG AGGGTCTAGT CTACCTGGGC CTCTCCTTCA ACCGCTTCCA CTGCATCCCC 1800

CCGGTGCTGG AGAAGTTCAA GGGGCTGGAG CGGCTGTGCC TGGCCGGGAA CAAGCTCTCC 1860

CTGCTGGACT TGTCTGCTCT GCAGTGGCTG CCCGCGCGAC ACGTCGACCT CAGGTTGAAC 1920

CGGCTGCAGA GCGTGGTGGT GGGGGAGGCG GGGGCGCTGG CCCACGTCAC CCAGCTGGAC 1980

GTGAGGGACG CCGGGCTGGA GGAGCTCGAC CTCCGGCCCC TCTCCAGCCT GGAGCTCCTG 2040

CGCTGCGACC GCAACAGCCT GGCCCGGCTC AGGGTCAGCG GCCACGCCCT CAAGGCCCTG 2100

CACGCGGCCA ACAATGAGCT GAAGCAGCTG GAGGTGGAGC CCGTGCCAGA GAGCCTGACC 2160

GCTCTGGATC TCTCCCGGAA CAAGCTGGAC AGTATTCCTG GATGGGTGAT TGGTTGCAGC 2220

AGACTGGAGG TGTTGGATAT CAATCACAAC TATGTCACCG AGCTGCCCTT ACAGTTCCTG 2280

TGCAGCAGCA GCCTGAGGAA GCTCCTGATT GGCTGGAACC GCCTGAGCTC GCTCGCCGAT 2340

AGGCTGGAGC GATGCCAGCT GGAGGTGCTG GACGTGCAAC ACAACCAGCT CACAGGGCTC 2400

CCCCACAACC TGTTCATCAA AGCACTGAGC CTGCGGTACC TGAACGCATC AGCCAATAAG 2460

CTGGAGAGCG TCCCCCCGGC GACCCAATCA GAGGAGAGCC TAAGCACACT CCAGGAGCTC 2520

TACCTGACCA ATAACAGCCT GACAGACAAG TGTGTGCCTT TGTTAGCGGG ACACACCCAC 2580

CTCAGGGTGC TCCATCTCGC TTTCAACCTG CTGCAAACCT TCGCTGCCAG TAAGCTGGCG 2640

GGCCTGGAGC AGCTGGAGGA GCTGGAGCTG AGTGGGAACC GCCTGCGCGC CGTCCCCACC 2700

ACCATCCTGA GCTGCAGGCG TCTCCACACG CTGGCCGCTC ACTCCAACTG CATCACCGTC 2760

TTCCCCGAGG TCCTCCAGCT CCCCGAGATC AAGTGTGTGG ATGTGAGCTG TAATGAGATA 2820

ACGGAGGTCT CCCTACCGGA GAGTCTGCCT GCTAAGCTGC AGGAGCTGGA CCTGACGGGG 2880

AACCCCAGGC TCACCCTGGA CCACAAGAGC CTGGAGCTGC TCAATAATAT CAGGTGCTTC 2940

AGGGTGGACC CCAGCCCGTC TGCCCCAGGG GCCAGCGAGG GGCCTGGGGT CCCTGCTGTC 3000

TGGAGCCACG GCTACACAGA GGCCTCGGGA GTCAAGAACA AGCTTTGTGT AGCGGCCCTC 3060

GCGCTGGACA GTTTCTGCGG GAGCCGCGAG GCACTGTACG GTGTGTTCGA CGGCGAGAGG 3120

AACGTTGAAG TGCCTTACCT GCTGCAGTGC ACCATGGGAG ATGTGCTGGC CGAGGAACTC 3180

CACAAGAGCC AAAGACGAGA GAACTACATG ACCAACACCT TTCTCACCAT GCAGAGGAAA 3240

CTGGGAACAG CGGGCCAGCG TCTTGGCGGC TCTGCGGCGC TGTGTCACAT CCGCCACGAC 3300

CCCGCCCCTC TCGGAGCGCG CGGGGGCTGC CTCACCCTGA CGGCGGCCAA CGTGGGGAAG 3360

TGCTGCGCCG TGCTGTGTCG CGCCGGGCGT GCCCTCCCGC TGTCCGTCAC GCACAGCGTC 3420

CGCGAGGAGG AGGAGCTACG CCGCGTGCGC ACGCACAACG CCATCGTCAC CGAGGACAAC 3480

AAGGTGAACG GCGTGACCGA CTCCACCCGC ATCATGGGCT ACTCCTTCCT GTGCCCCGCT 3540

GTGACGCCGC GGCCCCACGT CTCCACGGTG ACGCTAACGC CGCACGACGA GTTCTTCCTG 3600

CTGGGCAGCC GCGGCTTGTG GGACACGCTG TCGCCCAGCG AGGCGGTGGA GGCGGTGCGC 3660

AGCGTTCCCG ACTCCCTCGC CGCCGCCAAG AAGCTGGTGA CGCTGGCGCA GAGCTACGGC 3720

TGCCCGCTGA GCGCCAGCGC CGTGGTGGTC CAGCTCAGCA TCACCGACGA CTGCTGCGGC 3780

TTCTGCGAGC CCCCGCCGCC CCCGCCGGGC AGCCCCGGTC TGGGCACGCA CGGCGCGCGG 3840

GCTGAGGGGG CATTGTCGGG CACACTGGGT CGCAGGCCAC GCCCCAACGG CTCGGTGGCG 3900

TGCCAGGGGC GGAGCCAAGA TCTGATAGAG GTGGCGGCGG ACGCTCCCGC CAAGAAGGGC 3960

GGGTATTTCA ACGCCCCGGC CCAACCGGAC CCCGATGACC AGCTCATCAT CCCCCCAGAG 4020

CTGGAGGAGG AGGTCCGGCA GATTATCCAG CAACAGCAGC AACAGCAAGC AAACCAACAA 4080

GCACACAGCT TCCAGAAGCC CGCTGACTAC TTTGTCACGC CACTCTAG 4128

Domain Profile

S: 2     lvgvvsvngrrnemedavtsspnflkspekkdrlaffgvyDGhggsevakfcseklheil  61

         ++g+++ +g +n+++ a+ + ++f+ s+e+     ++gv+DG+++ ev + +++++ ++l

Q: 1002  SHGYTEASGVKNKLCVAALALDSFCGSREA-----LYGVFDGERNVEVPYLLQCTMGDVL  1056

         6899****************9999999775.....9************************

S: 62    aeelesseseerkvkkalakaFlstdeelkvleeksldidksGstavvalikds......  115

         aeel     ++++ +++++++Fl+++++l       ++ ++ G +a +++i+++

Q: 1057  AEELH----KSQRRENYMTNTFLTMQRKL------GTAGQRLGGSAALCHIRHDpaplga  1106

         ***99....8888899*************......999**********************

S: 116   .....klyvanvGdSravLcrngkavelssdHkpsredEleRieeaggsvilkdgaRvlG  170

              +l+ anvG+++avLcr g a++ls++H++ +e+El+R++ + + v++++  +v+G

Q: 1107  rggclTLTAANVGKCCAVLCRAGRALPLSVTHSVREEEELRRVRTHNAIVTEDN--KVNG  1164

         *****************************************************9..****

S: 171   vLavsRalGdlylkpyvtpePevtshrltsedefliLasDGlwdvvsneeavslvrdvle  230

         v+  +R +G  +l p vtp+P+v+ ++lt+ def+ L+s Glwd++s+ eav++vr+v +

Q: 1165  VTDSTRIMGYSFLCPAVTPRPHVSTVTLTPHDEFFLLGSRGLWDTLSPSEAVEAVRSVPD  1224

         ************************************************************

S: 231   kkeaeqeaakkLvklalargskdnvsaivv  260

               +aakkLv+la+++g+  + sa+vv

Q: 1225  ----SLAAAKKLVTLAQSYGCPLSASAVVV  1250

         ....*****************999999987

Domain Sequence
(FASTA)

SHGYTEASGV KNKLCVAALA LDSFCGSREA LYGVFDGERN VEVPYLLQCT MGDVLAEELH 60

KSQRRENYMT NTFLTMQRKL GTAGQRLGGS AALCHIRHDP APLGARGGCL TLTAANVGKC 120

CAVLCRAGRA LPLSVTHSVR EEEELRRVRT HNAIVTEDNK VNGVTDSTRI MGYSFLCPAV 180

TPRPHVSTVT LTPHDEFFLL GSRGLWDTLS PSEAVEAVRS VPDSLAAAKK LVTLAQSYGC 240

PLSASAVVV 249

Keyword

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>