EKS-GAM-00298

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-GAM-00298

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
TKL/RIPK	274.1	1.2E-81	8	268	261

Status

Unreviewed

Ensembl Protein

ENSGMOP00000019617

Gene Name

RIPK1

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSGMOG00000018226	ENSGMOP00000019617	ENSGMOT00000020096

Organism

Gadus morhua

Protein Length

509

Protein Sequence
(FASTA)

SADILTKDPL DYGGFGEVFL CRHKTLGPVV LKAVFTGLLR NEDSKRSLQE EGALMTKLCH 60

ERVVKLLGVI MEDGDYSLVM ELIPMGNLKS MLQQVTVPIS IRGRIVLEIL EGMVYLTENN 120

VIHKDLKPEN ILVDQDFHIK IADLGLATCE SWSKLTREES RRKSRSVATA GTQGAGTLSY 180

MAPEHLEDIN IRSTEKSDVY SFAIVLWVIL TGRDPYENAR NENQVCMCVR NGNRPAEDLI 240

AEDIPREMVD LMKSCWHKDP KLRPTFQDGP ASLLSSDRSG PGPVEASVED LHYEVPAGPI 300

QTDAQGVGTP PLEQKLDREL QYHKNGSYTF VGQPHSPTPE DGCYRPDMGR LVPPEQASAY 360

ERQKSWPTYP VPDTAAADYP AGLRFTPNTI GPLQDTGANA SAIQIGNNNS LSIRGSDSSL 420

GGPSNDQAVT EEHLNLLRDN IGSNWKRCAR RLGLTNVEVE AVDHDYCRDG LHEMVHQMLE 480

RWRMKEGSLG CTVGKLCQAL GSHIPVDVI 509

Nucleotide Sequence
(FASTA)

TCAGCTGATA TTTTAACCAA AGACCCGCTC GACTACGGAG GATTCGGTGA AGTCTTCTTA 60

TGCCGCCACA AAACCCTCGG ACCTGTGGTC CTGAAGGCTG TGTTCACTGG CCTTCTTCGA 120

AACGAAGATA GTAAGAGATC GCTGCAGGAG GAGGGGGCCC TGATGACCAA ACTGTGCCAT 180

GAGCGTGTGG TGAAGCTTCT GGGTGTCATT ATGGAGGACG GGGACTACTC CCTGGTCATG 240

GAGCTCATAC CAATGGGCAA TCTGAAGTCC ATGCTTCAAC AGGTTACAGT GCCAATATCG 300

ATCAGGGGCA GAATCGTTCT CGAGATTCTG GAAGGAATGG TTTACCTCAC AGAAAATAAT 360

GTCATACACA AGGACTTGAA GCCGGAGAAC ATCTTAGTGG ACCAGGACTT CCACATCAAG 420

ATCGCTGACC TCGGCCTGGC CACTTGCGAG TCCTGGAGCA AGCTGACTCG GGAGGAGTCC 480

CGCAGGAAGA GCCGCTCAGT GGCCACGGCG GGCACCCAGG GGGCCGGCAC GCTGAGCTAC 540

ATGGCCCCTG AGCACCTGGA GGACATCAAC ATCCGCTCCA CGGAGAAGTC TGACGTCTAC 600

AGCTTCGCCA TCGTGCTGTG GGTCATCCTC ACCGGCCGAG ACCCTTACGA GAACGCCCGA 660

AACGAGAACC AGGTGTGCAT GTGTGTCCGC AATGGAAACC GCCCAGCGGA GGACCTCATC 720

GCGGAGGACA TTCCCCGCGA GATGGTGGAT CTCATGAAGA GCTGCTGGCA CAAGGACCCG 780

AAGCTGAGGC CCACATTTCA GGACGGCCCC GCCTCCCTGC TGAGCTCAGA CCGAAGCGGC 840

CCCGGCCCCG TGGAGGCCAG CGTGGAGGAC CTCCACTACG AGGTGCCCGC CGGCCCCATC 900

CAGACAGACG CCCAGGGGGT GGGGACGCCA CCACTGGAGC AGAAGCTGGA CAGGGAGCTG 960

CAGTACCACA AGAACGGCAG CTACACCTTC GTGGGCCAGC CGCACTCGCC GACCCCAGAG 1020

GACGGCTGCT ACCGCCCCGA CATGGGCCGG CTCGTCCCTC CGGAGCAGGC CTCGGCCTAC 1080

GAGCGACAGA AGTCGTGGCC GACGTACCCA GTCCCGGACA CGGCGGCGGC CGACTACCCC 1140

GCCGGGCTCC GCTTCACTCC AAACACGATC GGCCCCCTGC AGGATACAGG TGCTAACGCG 1200

AGTGCTATCC AGATTGGTAA TAACAACTCT CTGAGCATCA GGGGCTCAGA CTCCAGTCTG 1260

GGTGGGCCGT CCAACGACCA GGCGGTGACT GAGGAACACC TGAACCTGCT GAGGGACAAC 1320

ATCGGCTCCA ACTGGAAGCG CTGCGCTCGG CGCCTGGGTC TGACCAACGT GGAGGTGGAG 1380

GCGGTGGACC ACGACTACTG CCGCGACGGG CTGCATGAGA TGGTGCACCA GATGCTAGAG 1440

CGCTGGAGGA TGAAGGAGGG CAGCTTGGGC TGCACTGTGG GCAAGCTCTG CCAGGCACTG 1500

GGTAGCCACA TCCCCGTGGA CGTGATC 1527

Domain Profile

S: 5     elvgsGgfgkvfkarhrkwrvevavkslvlktdaldse.rkelleeakkmeklrfsyvlk  63

         + ++ Ggfg+vf +rh++ +  v++   v+++ +++++ +++l ee++ m+kl +++v+k

Q: 8     DPLDYGGFGEVFLCRHKTLGPVVLKA--VFTGLLRNEDsKRSLQEEGALMTKLCHERVVK  65

         56899***************998887..66665555541567999***************

S: 64    llGvikeeeklglvmeymenGsLeklLkseielpwplkfRilkevvlgmnyLhslkPpll  123

         llGvi e + ++lvme ++ G+L+ +L++   +p +++ Ri+ e+ +gm+yL + +  ++

Q: 66    LLGVIMEDGDYSLVMELIPMGNLKSMLQQV-TVPISIRGRIVLEILEGMVYLTENN--VI  122

         ***************************976.9**********************99..**

S: 124   hkDLkpeniLlDnelhvkiaDfGlskfm........eessqskevsssa..egGtlaYla  173

         hkDLkpeniL+D+++h+kiaD+Gl+++         e+  +s++v +++    Gtl+Y+a

Q: 123   HKDLKPENILVDQDFHIKIADLGLATCEswskltreESRRKSRSVATAGtqGAGTLSYMA  182

         **************************9558899876444455555554454789******

S: 174   PelleevnkkaseksDvYsfaiviWavlakkepyeeeknslqiiivvkkgnRPeleevse  233

         Pe+le++n + +eksDvYsfaiv+W +l++++pye++ n+ q+ ++v++gnRP  + ++e

Q: 183   PEHLEDINIRSTEKSDVYSFAIVLWVILTGRDPYENARNENQVCMCVRNGNRPAEDLIAE  242

         ************************************************************

S: 234   elPrevpqlieLmkrcWeadpeeRPsFle  262

         ++Pre   +++Lmk+cW++dp+ RP+F++

Q: 243   DIPRE---MVDLMKSCWHKDPKLRPTFQD  268

         ***99...*******************96

Domain Sequence
(FASTA)

DPLDYGGFGE VFLCRHKTLG PVVLKAVFTG LLRNEDSKRS LQEEGALMTK LCHERVVKLL 60

GVIMEDGDYS LVMELIPMGN LKSMLQQVTV PISIRGRIVL EILEGMVYLT ENNVIHKDLK 120

PENILVDQDF HIKIADLGLA TCESWSKLTR EESRRKSRSV ATAGTQGAGT LSYMAPEHLE 180

DINIRSTEKS DVYSFAIVLW VILTGRDPYE NARNENQVCM CVRNGNRPAE DLIAEDIPRE 240

MVDLMKSCWH KDPKLRPTFQ D 261

Keyword

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>