EKS-LAC-00153

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-LAC-00153

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Atypical/RIO	213.9	2.5E-63	96	319	224

Status

Unreviewed

Ensembl Protein

ENSLACP00000000305

UniProt Accession

H2ZSD4;

Protein Name

Protein Synonyms/Alias

Gene Name

RIOK2

Gene Synonyms/Alias

RIOK2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSLACG00000000274	ENSLACP00000000305	ENSLACT00000000307

Organism

Latimeria chalumnae

Functional Description

Protein Length

542

Protein Sequence
(FASTA)

MGKLKVGLLR SLSREDFRVL TAVEMGMKNH EIVPASLIAS IASLKHGGCN KILRELVKHK 60

LLAYERTKTV QGYRLTCAGY DYLALKALSS RDVLNSVGNQ MGVGKESDIY IVANEEAQQF 120

ALKLHRLGRT SFRNLKNKRD YHKHRNKVSW LYLARLAAMK EFAYMKKVLI CSFFPLPSRC 180

CRFSHAEDDK LFLKYRECQV RHIDDPAAVY NELMELIVKL ANHGLIHGDF NEFNLMLDDE 240

DHATMIDFPQ MVSTSHPNAE WYFDRDVKCV RDFFKKRFSY ESELYPTFTD IRKESSLDVE 300

ITASGYTKEM QEDDELLHPV GPEEGDEEEG AKPVQPQREF ESKCIALTND MEQPGSSSEE 360

SEDEDVAGDS GNLQALGMAE LKPAIEELEG QSSSGKDRDN GDCSVIDFSG EERRFENTKD 420

TEDRTDQSDE PADLEDRDEC PDLVDLSSVN KEFRPFRDEE SMLHVNEHRQ RTTSFNSVGS 480

IGSCSTIPPE LIKQKIKRQL TKQKKAELRR RLQKGEASVY TKQRRENLQN IKCSLDSASF 540

WG 542

Nucleotide Sequence
(FASTA)

ATGGGGAAGC TGAAAGTTGG GCTACTGAGA TCTCTTTCCC GGGAGGACTT CAGGGTTCTC 60

ACTGCTGTTG AAATGGGTAT GAAAAACCAT GAAATAGTTC CAGCTAGTCT AATTGCTTCA 120

ATTGCTAGCC TTAAGCATGG TGGATGCAAT AAAATTCTGA GAGAACTGGT TAAACACAAA 180

CTGTTGGCAT ATGAACGCAC AAAAACTGTA CAGGGTTATC GGCTGACTTG TGCGGGATAT 240

GATTACTTGG CCTTGAAAGC TCTGTCTTCT CGAGATGTCC TTAACTCTGT TGGAAATCAA 300

ATGGGTGTTG GCAAAGAATC AGATATTTAC ATTGTTGCAA ATGAAGAGGC ACAACAGTTT 360

GCATTAAAAC TGCACAGGCT AGGCCGGACC TCTTTCCGTA ACCTTAAAAA CAAACGTGAC 420

TACCACAAGC ATCGGAACAA GGTCTCCTGG CTGTATTTGG CCCGTCTTGC AGCCATGAAG 480

GAATTTGCGT ACATGAAGAA AGTGTTGATA TGTAGTTTTT TTCCCCTCCC ATCCAGATGC 540

TGCCGCTTTT CCCATGCTGA GGACGACAAA CTCTTTTTGA AATACCGTGA ATGCCAGGTC 600

CGCCATATTG ATGACCCCGC AGCTGTGTAC AATGAGTTGA TGGAACTGAT TGTGAAACTT 660

GCTAACCACG GCTTAATCCA TGGAGATTTC AATGAGTTTA ACCTGATGCT GGATGATGAG 720

GACCACGCAA CAATGATTGA TTTTCCACAG ATGGTGTCTA CCTCCCACCC AAATGCAGAA 780

TGGTATTTTG ACAGGGATGT GAAATGTGTC CGGGATTTCT TTAAGAAACG ATTCAGCTAT 840

GAAAGTGAGC TTTATCCAAC ATTCACTGAT ATCCGGAAAG AGTCCTCTTT AGATGTGGAG 900

ATCACAGCCA GCGGCTACAC TAAGGAAATG CAAGAGGATG ATGAGCTACT TCACCCTGTA 960

GGGCCTGAGG AAGGGGATGA AGAGGAGGGG GCAAAGCCTG TACAACCTCA GAGAGAGTTT 1020

GAAAGCAAAT GTATAGCACT TACTAACGAT ATGGAGCAGC CTGGCAGCAG CAGTGAAGAA 1080

TCGGAAGATG AAGATGTTGC TGGGGACAGT GGAAATCTAC AGGCTCTGGG CATGGCTGAA 1140

CTCAAACCCG CTATAGAAGA ACTTGAAGGG CAAAGTAGCA GTGGGAAAGA CAGAGATAAT 1200

GGAGATTGCT CTGTAATTGA TTTTTCTGGG GAAGAAAGGA GATTTGAAAA TACCAAAGAC 1260

ACAGAAGATC GGACAGACCA GAGTGATGAG CCAGCAGACC TAGAAGATAG AGATGAATGT 1320

CCTGATCTTG TGGACTTGTC TTCTGTGAAC AAAGAATTTA GACCTTTCAG AGATGAAGAA 1380

AGCATGCTGC ATGTAAACGA ACACAGACAA AGAACTACAA GTTTCAATTC TGTCGGGAGT 1440

ATTGGGAGCT GTTCGACAAT TCCACCCGAG CTGATAAAGC AGAAAATAAA ACGCCAGTTG 1500

ACAAAACAGA AGAAGGCAGA GCTGCGGAGA CGCTTGCAGA AGGGGGAGGC TAGCGTTTAT 1560

ACGAAACAGC GCCGGGAGAA CCTACAAAAT ATTAAATGCA GTTTGGACTC AGCAAGTTTC 1620

TGGGGATGA 1629

Domain Profile

S: 2     svgntigvgkesdvykvsekngeeraiKiy...ktsllvlknrdkYvdgefrfkksrska  58

         svgn++gvgkesd+y v++++ +++a+K++   +ts+++lkn+++Y       +k+r+k+

Q: 96    SVGNQMGVGKESDIYIVANEEAQQFALKLHrlgRTSFRNLKNKRDY-------HKHRNKV  148

         79********************************************.......9******

S: 59    nprklsrlwAeKEfrnlkrlyekgv.pvPepidlkrhvlvmeligrdgypapklkdvklk  117

         ++++l rl+A+KEf+++k++    + p P      +h+   +l    +y  ++++    +

Q: 149   SWLYLARLAAMKEFAYMKKVLICSFfPLPSRCCRFSHAEDDKLF--LKYRECQVR----H  202

         *****************987766655***********9999888..789999999....9

S: 118   eeeikelYsdllalivklynegrLvHaDlsEfnill.eddklvliDvsqsveieHpdale  176

          ++ + +Y++l++livkl+n+g L+H+D++Efn++l ++d+ ++iD++q+v+++Hp+a++

Q: 203   IDDPAAVYNELMELIVKLANHG-LIHGDFNEFNLMLdDEDHATMIDFPQMVSTSHPNAEW  261

         9*********************.*************66799*******************

S: 177   flrrDvknvkefFkkklvy.........dvlrerelfelvsasgltkekeaddeilea  225

         +++rDvk+v++fFkk+++y         d+++e +l+ +++asg+tke+++dde+l++

Q: 262   YFDRDVKCVRDFFKKRFSYeselyptftDIRKESSLDVEITASGYTKEMQEDDELLHP  319

         ******************************************************9986

Domain Sequence
(FASTA)

SVGNQMGVGK ESDIYIVANE EAQQFALKLH RLGRTSFRNL KNKRDYHKHR NKVSWLYLAR 60

LAAMKEFAYM KKVLICSFFP LPSRCCRFSH AEDDKLFLKY RECQVRHIDD PAAVYNELME 120

LIVKLANHGL IHGDFNEFNL MLDDEDHATM IDFPQMVSTS HPNAEWYFDR DVKCVRDFFK 180

KRFSYESELY PTFTDIRKES SLDVEITASG YTKEMQEDDE LLHP 224

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR018934	; RIO-like_kinase.
IPR015285	; RIO2_kinase_winged_hlx_N.
IPR018935	; RIO_kinase_CS.
IPR011991	; WHTH_trsnscrt_rep_DNA-bd.

Pfam

PF01163	; RIO1; 1.
PF09202	; Rio2_N; 1.

SMARTs

Prosites

PS01245

; RIO1; 1.

Prints

Created Date

20-Feb-2013