EKS-LAC-00151

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-LAC-00151

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Atypical/RIO	315.4	2.4E-94	193	404	212

Status

Unreviewed

Ensembl Protein

ENSLACP00000000332

UniProt Accession

H2ZSG1;

Protein Name

Serine/threonine-protein kinase RIO1

Protein Synonyms/Alias

Gene Name

RIOK1

Gene Synonyms/Alias

RIOK1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSLACG00000000300	ENSLACP00000000332	ENSLACT00000000334

Organism

Latimeria chalumnae

Functional Description

Protein Length

566

Protein Sequence
(FASTA)

MDGRGDLLAG VVPGQFDDAE SSGSEFPSPD EKEKTVIEVE KIKDLRVVVP EEEEVADDSS 60

EGEDEEEEDD DDDWDWDEAG GNLTKRYTAS RGNNQQANKQ KPSSYSTKMS TPTDKVLRKF 120

ENKINLGKCK NVVSRFESVT RKGQIQSIEM FALNSLYSKR TEVVHCRLRL LIVCDVSKKT 180

GSNLCVCVWG GGIANVYHAS TNNGESRAIK IYKTSILMFK DRDKYVSGEF RFRHGYCKGN 240

PRKMVRTWAE KEMRNLIRLQ TAEIPSPEPI LLRSHVLVMG FIGKNDMPAP LLKNAQLSES 300

KARELYLQVI QYMRRMYQDA RLVHADLSEF NMLYHNGGIY IIDVSQSVEH DHPHALEFLR 360

KDCANVNDFF RKHDVAVMTV KELFGFVTDP SITKENIDDY LEKAMEIASQ RTEDERSNQD 420

KVDEEVFKNA YIPRTLTEVK NYERDVDDMM NLKEEDIALN YQHDNILYQT VTGLKRDLSG 480

VQMVPALLEN KGDGHCNSEE ADSPASSNSD SEEEQIHPKD RPQMSEADKK ERKKIAKEAQ 540

REKRKNKVPK HVKKRKEKLA KIKKGK 566

Nucleotide Sequence
(FASTA)

ATGGACGGCA GGGGAGACCT ACTCGCCGGG GTCGTCCCGG GACAGTTTGA CGACGCGGAG 60

TCCTCGGGCA GTGAGTTCCC TTCTCCTGAT GAGAAAGAGA AAACTGTAAT AGAAGTGGAG 120

AAGATTAAAG ACCTACGGGT GGTCGTCCCT GAAGAAGAAG AGGTGGCTGA TGACAGCAGC 180

GAAGGGGAAG ATGAGGAGGA GGAGGATGAT GATGATGACT GGGATTGGGA TGAAGCTGGC 240

GGAAATCTCA CAAAACGCTA TACAGCATCG AGAGGAAACA ATCAACAGGC AAATAAACAG 300

AAACCAAGTA GTTATTCAAC GAAAATGTCC ACTCCTACTG ACAAAGTCTT AAGAAAGTTT 360

GAAAATAAAA TTAATCTTGG TAAGTGCAAG AATGTTGTCT CCAGATTTGA AAGTGTGACT 420

AGAAAAGGAC AAATCCAGTC AATAGAAATG TTTGCATTGA ACAGTCTTTA TTCTAAAAGG 480

ACTGAGGTTG TGCACTGTAG ACTTAGGCTT TTAATAGTCT GTGATGTGTC TAAAAAAACA 540

GGAAGTAACT TATGTGTGTG TGTGTGGGGG GGGGGAATAG CTAATGTGTA TCACGCCTCT 600

ACAAATAATG GGGAGAGCAG AGCTATAAAG ATCTATAAGA CCTCCATCTT GATGTTTAAG 660

GATCGGGATA AGTATGTTAG TGGGGAATTC AGATTCCGCC ATGGATACTG CAAAGGAAAT 720

CCAAGAAAAA TGGTTAGAAC GTGGGCAGAA AAAGAAATGA GAAACTTAAT CAGGTTGCAA 780

ACAGCAGAAA TACCCTCTCC AGAGCCTATC TTGTTAAGAA GCCATGTTCT TGTTATGGGC 840

TTCATTGGTA AAAATGATAT GCCAGCTCCC CTGTTGAAGA ATGCACAGTT GTCCGAATCC 900

AAAGCTCGGG AGCTGTATCT CCAGGTCATT CAGTACATGA GGCGAATGTA CCAGGATGCC 960

AGGCTGGTGC ATGCTGATCT CAGTGAATTC AATATGCTGT ATCACAATGG AGGGATTTAT 1020

ATTATTGATG TATCGCAGTC AGTGGAGCAT GACCACCCAC ATGCACTAGA GTTCTTGAGA 1080

AAAGACTGTG CAAATGTTAA TGATTTTTTC CGAAAACATG ATGTTGCAGT AATGACTGTG 1140

AAGGAGCTCT TTGGGTTTGT TACAGATCCT TCTATTACCA AAGAAAATAT AGATGACTAC 1200

TTGGAAAAGG CAATGGAAAT TGCTTCACAG AGGACAGAGG ATGAAAGATC AAACCAGGAC 1260

AAAGTAGATG AAGAGGTGTT TAAGAACGCA TACATTCCAA GAACCCTGAC CGAAGTTAAA 1320

AATTATGAAA GGGATGTGGA CGATATGATG AACCTAAAGG AAGAAGATAT AGCCTTAAAT 1380

TACCAACATG ACAATATTCT ATATCAGACT GTGACCGGAC TGAAGAGAGA CCTGTCAGGC 1440

GTTCAGATGG TCCCTGCTCT TCTTGAAAAC AAAGGAGATG GGCACTGTAA CTCAGAGGAA 1500

GCAGACAGTC CAGCTTCTTC AAACTCAGAC TCTGAAGAAG AACAGATCCA CCCTAAAGAT 1560

CGTCCACAGA TGTCTGAAGC AGACAAAAAG GAAAGGAAGA AGATAGCTAA AGAAGCCCAA 1620

AGAGAGAAGA GGAAAAACAA GGTTCCAAAG CATGTGAAGA AACGTAAAGA AAAATTAGCC 1680

AAGATAAAGA AAGGCAAATA G 1701

Domain Profile

S: 12    esdvykvsekngeeraiKiyktsllvlknrdkYvdgefrfkksrskanprklsrlwAeKE  71

          ++vy++s++nge+raiKiykts+l +k+rdkYv+gefrf+++++k nprk++r+wAeKE

Q: 193   IANVYHASTNNGESRAIKIYKTSILMFKDRDKYVSGEFRFRHGYCKGNPRKMVRTWAEKE  252

         589*********************************************************

S: 72    frnlkrlyekgvpvPepidlkrhvlvmeligrdgypapklkdvklkeeeikelYsdllal  131

         +rnl+rl+++++p Pepi l++hvlvm +ig++++pap lk+ +l+e++++elY +++++

Q: 253   MRNLIRLQTAEIPSPEPILLRSHVLVMGFIGKNDMPAPLLKNAQLSESKARELYLQVIQY  312

         ************************************************************

S: 132   ivklynegrLvHaDlsEfnilleddklvliDvsqsveieHpdaleflrrDvknvkefFkk  191

         ++++y+++rLvHaDlsEfn+l++++++++iDvsqsve++Hp+aleflr+D++nv++fF+k

Q: 313   MRRMYQDARLVHADLSEFNMLYHNGGIYIIDVSQSVEHDHPHALEFLRKDCANVNDFFRK  372

         ************************************************************

S: 192   klvydvlrerelfelvsasgltkekead....d  220

         + v +v++++elf +v++ ++tke+ +d

Q: 373   HDV-AVMTVKELFGFVTDPSITKENIDDylekA  404

         ***.*********************99755440

Domain Sequence
(FASTA)

IANVYHASTN NGESRAIKIY KTSILMFKDR DKYVSGEFRF RHGYCKGNPR KMVRTWAEKE 60

MRNLIRLQTA EIPSPEPILL RSHVLVMGFI GKNDMPAPLL KNAQLSESKA RELYLQVIQY 120

MRRMYQDARL VHADLSEFNM LYHNGGIYII DVSQSVEHDH PHALEFLRKD CANVNDFFRK 180

HDVAVMTVKE LFGFVTDPSI TKENIDDYLE KA 212

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>