EKS-LAC-00218

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-LAC-00218

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDKL	508.2	5.3E-153	4	287	284

Status

Unreviewed

Ensembl Protein

ENSLACP00000000373

UniProt Accession

H2ZSK2;

Protein Name

Protein Synonyms/Alias

Gene Name

CDKL2

Gene Synonyms/Alias

CDKL2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSLACG00000000336	ENSLACP00000000373	ENSLACT00000000375

Organism

Latimeria chalumnae

Functional Description

Protein Length

451

Protein Sequence
(FASTA)

MDKYENLGLV GEGSYGMVIK CRNKETGRVV AIKKFLESDD DKMVKKIAMR EIKLLKQLRH 60

QNLVNLLEVC KKKKRWYLVF EFVDRTVLDD LEQFPNGLDY NKVRKYLFQI LRGIAFCHTH 120

NIIHRDIKPE NILVSHSGVV KLCDFGFART LAAPGEVYTD YVATRWYRAP ELLVGDTKYG 180

KAVDVWAVGC LITEMLTGEP LFPGDSDIDQ LYHIMKCFGN LTPRHEELYY KNPLFSGVRL 240

PDIREVEPLE RRFPKLSPLM LDLIKKCLQT DPDKRHSCVE LLKHDVFTKD GFAERFTQEL 300

SAQIEKDNLP LPKRSKMSKK DKVESSSENK KIANLIKQEL INSEKVTESR VDAKLIKVKG 360

SKSDLEKTER MEKPTNTTVQ HSPEKTTESG MGPSKGAPHT CSKELGGSVD RPKTPAVTMI 420

PPITQSTSTI TSSSKNISSG GPAAQGHHSY R 451

Nucleotide Sequence
(FASTA)

ATGGACAAGT ATGAAAATCT GGGGCTGGTT GGTGAAGGAA GTTATGGGAT GGTGATTAAA 60

TGTAGGAACA AAGAAACTGG GAGAGTTGTT GCCATTAAGA AATTTTTGGA AAGCGATGAT 120

GACAAAATGG TGAAGAAAAT CGCTATGCGA GAAATCAAGC TGCTAAAGCA ACTAAGGCAC 180

CAGAACTTGG TGAACCTGCT GGAGGTGTGC AAGAAGAAGA AGCGCTGGTA CCTGGTGTTT 240

GAGTTTGTGG ATCGCACGGT CCTGGATGAC CTGGAACAAT TTCCAAATGG ACTTGACTAC 300

AACAAAGTTC GGAAGTATCT CTTTCAAATT CTGAGAGGAA TTGCCTTTTG TCATACTCAT 360

AATATTATAC ATAGAGATAT TAAACCAGAA AACATATTGG TCTCTCATTC TGGTGTCGTA 420

AAGCTGTGTG ACTTTGGATT TGCACGTACG TTGGCGGCTC CCGGAGAGGT GTACACAGAT 480

TACGTGGCTA CACGCTGGTA TCGAGCTCCT GAGCTACTGG TTGGAGACAC CAAGTATGGC 540

AAAGCAGTGG ATGTGTGGGC CGTTGGTTGT CTGATAACAG AGATGTTGAC AGGGGAACCA 600

CTTTTTCCTG GGGATTCCGA TATTGACCAG CTGTATCATA TTATGAAATG TTTTGGTAAC 660

TTAACTCCTA GGCATGAAGA GCTGTACTAT AAGAACCCAC TCTTCTCTGG TGTGAGATTA 720

CCTGACATTA GGGAAGTGGA GCCCCTAGAA AGGAGGTTTC CCAAGCTCTC GCCTTTAATG 780

CTGGACTTAA TAAAGAAGTG TTTGCAGACT GACCCCGATA AAAGACATTC TTGTGTGGAG 840

CTGCTGAAGC ATGATGTATT TACAAAGGAT GGGTTTGCTG AAAGGTTTAC TCAGGAGCTC 900

AGTGCTCAGA TTGAAAAAGA CAATCTACCT CTACCCAAGA GATCAAAAAT GAGCAAGAAG 960

GACAAAGTGG AGTCTTCAAG TGAAAACAAG AAGATAGCAA ATCTTATTAA GCAGGAATTA 1020

ATAAACTCTG AAAAAGTCAC AGAAAGCAGA GTGGACGCTA AACTGATAAA GGTGAAAGGA 1080

TCAAAGTCAG ACCTGGAAAA GACTGAAAGG ATGGAGAAAC CTACTAATAC AACTGTACAG 1140

CATTCTCCTG AGAAGACAAC AGAGAGTGGA ATGGGCCCCA GCAAGGGTGC ACCTCATACA 1200

TGCTCCAAAG AGTTAGGTGG CAGTGTTGAC CGTCCAAAGA CACCAGCAGT GACCATGATC 1260

CCTCCAATCA CACAGAGCAC ATCCACAATC ACATCTTCCA GTAAGAACAT CAGTTCTGGG 1320

GGACCTGCTG CTCAGGGACA CCACAGCTAC AGG 1353

Domain Profile

S: 1     yeklgkvGeGsyGvvlkcrnkdtgqivaikkfleseddkevkkialreikllkqlkhenl  60

         ye+lg vGeGsyG+v+kcrnk+tg++vaikkfles+ddk+vkkia+reikllkql+h+nl

Q: 4     YENLGLVGEGSYGMVIKCRNKETGRVVAIKKFLESDDDKMVKKIAMREIKLLKQLRHQNL  63

         9***********************************************************

S: 61    vnllevfrrkkklylvfeyvdktvldelerypnGveeelvkkilyqilkaiefchknnii  120

         vnllev+++kk++ylvfe+vd+tvld+le++pnG+++++v+k+l+qil++i+fch++nii

Q: 64    VNLLEVCKKKKRWYLVFEFVDRTVLDDLEQFPNGLDYNKVRKYLFQILRGIAFCHTHNII  123

         ************************************************************

S: 121   hrdikpenilisksgvvklcdfGfarllaapgdvytdyvatrwyrapellvgdtkyGksv  180

         hrdikpenil+s+sgvvklcdfGfar+laapg+vytdyvatrwyrapellvgdtkyGk+v

Q: 124   HRDIKPENILVSHSGVVKLCDFGFARTLAAPGEVYTDYVATRWYRAPELLVGDTKYGKAV  183

         ************************************************************

S: 181   dvwaiGcllaelltGeplfpgksdvdqlykirktlGeliprhqkifsknevfaGvklpev  240

         dvwa+Gcl++e+ltGeplfpg+sd+dqly+i+k++G+l+prh+++++kn++f+Gv+lp++

Q: 184   DVWAVGCLITEMLTGEPLFPGDSDIDQLYHIMKCFGNLTPRHEELYYKNPLFSGVRLPDI  243

         ************************************************************

S: 241   edleslekkypklnevlldllkkclkldpaerlsceellkheyf  284

         +++e+le+++pkl++++ldl+kkcl+ dp++r sc ellkh++f

Q: 244   REVEPLERRFPKLSPLMLDLIKKCLQTDPDKRHSCVELLKHDVF  287

         ******************************************98

Domain Sequence
(FASTA)

YENLGLVGEG SYGMVIKCRN KETGRVVAIK KFLESDDDKM VKKIAMREIK LLKQLRHQNL 60

VNLLEVCKKK KRWYLVFEFV DRTVLDDLEQ FPNGLDYNKV RKYLFQILRG IAFCHTHNII 120

HRDIKPENIL VSHSGVVKLC DFGFARTLAA PGEVYTDYVA TRWYRAPELL VGDTKYGKAV 180

DVWAVGCLIT EMLTGEPLFP GDSDIDQLYH IMKCFGNLTP RHEELYYKNP LFSGVRLPDI 240

REVEPLERRF PKLSPLMLDL IKKCLQTDPD KRHSCVELLK HDVF 284

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013