EKS-LAC-00444

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-LAC-00444

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
AGC/SGK	441.5	1.3E-132	97	358	262

Status

Unreviewed

Ensembl Protein

ENSLACP00000001028

UniProt Accession

H2ZUF7;

Protein Name

Protein Synonyms/Alias

Gene Name

SGK1

Gene Synonyms/Alias

SGK1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSLACG00000000919	ENSLACP00000001028	ENSLACT00000001037

Organism

Latimeria chalumnae

Functional Description

Protein Length

434

Protein Sequence
(FASTA)

MTIRSDSSGQ PLTYSKMRGM VAILIAFMKQ RRMGLNDFIQ KLATNSYSYK HSEVQTILNI 60

TPQDSELMNS TSSSPPSPSQ QINLGPFSNP QAKPSDFNFL TVIGKGSFGK VLLARHKTDE 120

QFYAVKVLQK KAILKKKEEK HIMSERNVLL KNVKHPFLVG LHYSFQTADK LYFVLDYING 180

GELFYHLQRE RCFLEPRARF YAAEIASALG YLHSLNIVYR DLKPENILLD SQGHIILTDF 240

GLCKENIEPN GTTSTFCGTP EDFPSLLPPP LPISELLGSE KGLCIRFTLV YLFFFSQPPF 300

YSRNTAEMYD NILNKPLQLK PNITNSARHL LEGLLQKDRI QRLGAKDDFL EIKNHVFFSP 360

INWDDLINKK ITPPFNPNVT GPNDLQHFDP EFTEEPVPSS ICQTPDSALI TASVKEAAEA 420

FLGFSYAPSM DSFL 434

Nucleotide Sequence
(FASTA)

ATGACTATTA GAAGCGACTC CTCTGGGCAA CCCCTAACCT ACTCTAAAAT GAGAGGCATG 60

GTTGCTATTC TTATTGCTTT TATGAAACAG AGAAGGATGG GACTGAATGA TTTTATTCAA 120

AAACTAGCCA CAAACTCGTA CTCCTACAAG CATTCTGAGG TCCAGACAAT TCTGAACATC 180

ACACCTCAAG ACTCAGAGCT CATGAACTCC ACTAGCTCCT CTCCACCTAG CCCATCCCAG 240

CAGATCAACC TTGGTCCATT CTCTAACCCT CAGGCCAAAC CATCGGATTT CAACTTTTTG 300

ACTGTGATTG GCAAAGGCAG CTTTGGGAAA GTTCTCCTTG CAAGACACAA GACCGATGAA 360

CAGTTCTATG CAGTCAAAGT TTTGCAGAAG AAGGCCATTT TGAAAAAGAA AGAGGAGAAA 420

CACATCATGT CAGAGCGCAA TGTCTTGTTA AAGAATGTGA AACACCCTTT CCTGGTTGGG 480

CTCCATTATT CGTTCCAGAC AGCAGACAAA CTGTACTTTG TCCTGGACTA CATCAATGGA 540

GGAGAGTTGT TTTATCATCT TCAACGGGAA CGCTGCTTCC TGGAGCCGCG AGCCAGATTT 600

TATGCTGCTG AGATCGCTAG TGCACTAGGC TACCTGCACT CCCTGAACAT TGTTTACAGA 660

GACTTGAAAC CAGAAAACAT TCTATTGGAC TCCCAGGGGC ACATAATTTT GACTGACTTT 720

GGCCTTTGCA AGGAGAACAT TGAACCCAAT GGCACTACTT CCACATTTTG TGGAACACCA 780

GAGGATTTTC CCTCTCTTCT CCCCCCCCCC CTTCCCATCT CAGAATTGTT AGGAAGTGAA 840

AAGGGATTAT GTATTAGATT CACCTTAGTT TATTTATTTT TTTTTTCACA GCCTCCCTTC 900

TACAGCAGAA ACACAGCTGA GATGTATGAC AATATTTTAA ACAAGCCTCT GCAGTTGAAG 960

CCAAACATCA CCAACTCTGC AAGACACCTT TTGGAGGGGC TCTTACAGAA GGATAGGATA 1020

CAGAGGCTTG GTGCAAAGGA TGACTTTTTG GAGATCAAAA ACCATGTCTT CTTCTCACCA 1080

ATTAATTGGG ATGATCTTAT TAACAAGAAG ATTACACCCC CCTTCAACCC TAATGTGACT 1140

GGTCCCAATG ACCTTCAGCA TTTTGATCCA GAGTTCACCG AGGAGCCTGT CCCAAGTTCC 1200

ATTTGCCAAA CTCCAGATAG TGCTCTGATA ACTGCGAGTG TCAAAGAAGC TGCCGAAGCG 1260

TTTTTAGGAT TCTCCTATGC TCCATCCATG GATTCTTTTC TATGA 1305

Domain Profile

S: 1     fdflkvigkgsfgkvllakrkadekfyavkvlqkkailkkkeekhimaernvllknvkhp  60

         f+fl+vigkgsfgkvlla++k+de+fyavkvlqkkailkkkeekhim+ernvllknvkhp

Q: 97    FNFLTVIGKGSFGKVLLARHKTDEQFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKHP  156

         89**********************************************************

S: 61    flvglhysfqtaeklyfvldyvnggelffhlqrersfleprarfyaaeiasalgylhsln  120

         flvglhysfqta+klyfvldy+nggelf+hlqrer+fleprarfyaaeiasalgylhsln

Q: 157   FLVGLHYSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSLN  216

         ************************************************************

S: 121   ivyrdlkpenilldskghvvltdfglckeeieaedttstfcgtpey...lapevlrkkpy  177

         ivyrdlkpenillds+gh++ltdfglcke+ie + ttstfcgtpe    l p  l

Q: 217   IVYRDLKPENILLDSQGHIILTDFGLCKENIEPNGTTSTFCGTPEDfpsLLPPPLPISEL  276

         ********************************************9722233333333333

S: 178   drtvdwwclg.avlyemlyglppfysrdvaemydnilnkplqlkpgisvaalelleelle  236

           +    c+  +++y +++  ppfysr++aemydnilnkplqlkp+i+++a++lle+ll+

Q: 277   LGSEKGLCIRfTLVYLFFFSQPPFYSRNTAEMYDNILNKPLQLKPNITNSARHLLEGLLQ  336

         344556777626779999******************************************

S: 237   kdrkkrlgakedfleiknhvff  258

         kdr +rlgak+dfleiknhvff

Q: 337   KDRIQRLGAKDDFLEIKNHVFF  358

         *********************9

Domain Sequence
(FASTA)

FNFLTVIGKG SFGKVLLARH KTDEQFYAVK VLQKKAILKK KEEKHIMSER NVLLKNVKHP 60

FLVGLHYSFQ TADKLYFVLD YINGGELFYH LQRERCFLEP RARFYAAEIA SALGYLHSLN 120

IVYRDLKPEN ILLDSQGHII LTDFGLCKEN IEPNGTTSTF CGTPEDFPSL LPPPLPISEL 180

LGSEKGLCIR FTLVYLFFFS QPPFYSRNTA EMYDNILNKP LQLKPNITNS ARHLLEGLLQ 240

KDRIQRLGAK DDFLEIKNHV FF 262

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR000961	; AGC-kinase_C.
IPR011009	; Kinase-like_dom.
IPR017892	; Pkinase_C.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069	; Pkinase; 1.
PF00433	; Pkinase_C; 1.

SMARTs

SM00133	; S_TK_X; 1.
SM00220	; S_TKc; 1.

Prosites

PS51285	; AGC_KINASE_CTER; 1.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013