EKS-LAC-00441

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-LAC-00441

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
AGC/SGK	531.5	4.7E-160	36	293	258

Status

Unreviewed

Ensembl Protein

ENSLACP00000001562

UniProt Accession

H2ZVZ1;

Protein Name

Protein Synonyms/Alias

Gene Name

SGK2

Gene Synonyms/Alias

SGK2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSLACG00000001395	ENSLACP00000001562	ENSLACT00000001575

Organism

Latimeria chalumnae

Functional Description

Protein Length

369

Protein Sequence
(FASTA)

MDRSKNLVND AQPRKPDTGD INLGPSANPN AKPTDFDFLK VIGKGSYGKV LLAKRKSDGK 60

FYAVKVLQKK TILHRKEQRH IMAERNVLLK NVKHPFLVGL HYSFQTPEKL YFVLDYVNGG 120

EVFFHLQQER SFPEPRARFY AAEVASAIGY LHSLNIVYRD LKPENILLDS QGHIVLTDFG 180

LCKEGIEPEG TTSTFCGTPE YLAPEVLRKQ PYDRTVDWWC LGAVLYEMLY GLPPFYSQDV 240

AEMYDKILHQ PLQLRTGKTV AACDILQGLL QKDQKKRLGA KADFLEIKNH MFFNSINWDD 300

LYHKRITPPY NPNVNGPNDL RHFDPEFTQE AVSNSVGRTP EQATSSSSAS NAFLGFSYAA 360

TEENFLRNC 369

Nucleotide Sequence
(FASTA)

ATGGATCGCT CCAAAAATCT GGTCAACGAT GCTCAGCCCA GGAAACCAGA CACTGGTGAC 60

ATTAATCTGG GTCCCTCAGC CAATCCAAAT GCCAAACCTA CAGACTTTGA TTTTCTAAAA 120

GTTATTGGAA AGGGGAGCTA TGGAAAAGTT CTGTTGGCAA AGCGTAAATC AGATGGAAAG 180

TTCTATGCGG TAAAAGTTTT ACAGAAGAAA ACCATTCTAC ATAGAAAAGA GCAAAGACAC 240

ATCATGGCTG AACGCAATGT TCTCCTGAAG AATGTCAAAC ATCCCTTCCT GGTGGGGCTG 300

CATTATTCCT TCCAGACACC AGAGAAACTC TACTTTGTCT TGGACTATGT GAATGGTGGG 360

GAGGTGTTTT TCCATCTACA ACAAGAGCGC AGTTTCCCAG AACCCCGAGC TCGCTTTTAT 420

GCTGCTGAAG TTGCCAGTGC AATTGGCTAC CTTCATTCTC TAAACATTGT TTACAGGGAT 480

CTGAAGCCAG AAAATATTCT GTTGGATTCA CAGGGACACA TTGTGCTAAC AGATTTTGGA 540

CTCTGTAAAG AAGGAATAGA GCCAGAGGGA ACAACTTCCA CCTTCTGTGG AACTCCTGAA 600

TACTTGGCCC CTGAAGTGCT GAGGAAGCAG CCTTATGATC GGACAGTGGA CTGGTGGTGT 660

CTGGGGGCAG TCCTTTATGA GATGTTGTAT GGCCTGCCCC CCTTTTACAG CCAAGATGTT 720

GCGGAGATGT ATGATAAGAT TTTGCACCAG CCTCTCCAGT TGCGAACGGG GAAGACAGTA 780

GCTGCATGTG ACATCCTGCA GGGACTGCTA CAGAAGGACC AGAAGAAGAG ACTGGGAGCC 840

AAGGCAGACT TTCTTGAAAT TAAGAATCAC ATGTTCTTTA ATTCTATTAA CTGGGATGAT 900

CTTTACCACA AGCGAATAAC GCCTCCTTAT AACCCAAATG TGAATGGTCC AAATGACCTT 960

CGACACTTTG ACCCAGAATT CACCCAGGAA GCTGTTTCAA ACTCAGTTGG CCGAACACCT 1020

GAGCAAGCCA CCAGTAGCTC CAGTGCTTCA AATGCATTTT TAGGTTTTTC TTATGCAGCT 1080

ACAGAAGAAA ATTTCTTAAG GAACTGTTAA 1110

Domain Profile

S: 1     fdflkvigkgsfgkvllakrkadekfyavkvlqkkailkkkeekhimaernvllknvkhp  60

         fdflkvigkgs+gkvllakrk+d+kfyavkvlqkk+il++ke++himaernvllknvkhp

Q: 36    FDFLKVIGKGSYGKVLLAKRKSDGKFYAVKVLQKKTILHRKEQRHIMAERNVLLKNVKHP  95

         9***********************************************************

S: 61    flvglhysfqtaeklyfvldyvnggelffhlqrersfleprarfyaaeiasalgylhsln  120

         flvglhysfqt+eklyfvldyvngge+ffhlq+ersf+eprarfyaae+asa+gylhsln

Q: 96    FLVGLHYSFQTPEKLYFVLDYVNGGEVFFHLQQERSFPEPRARFYAAEVASAIGYLHSLN  155

         ************************************************************

S: 121   ivyrdlkpenilldskghvvltdfglckeeieaedttstfcgtpeylapevlrkkpydrt  180

         ivyrdlkpenillds+gh+vltdfglcke+ie e ttstfcgtpeylapevlrk+pydrt

Q: 156   IVYRDLKPENILLDSQGHIVLTDFGLCKEGIEPEGTTSTFCGTPEYLAPEVLRKQPYDRT  215

         ************************************************************

S: 181   vdwwclgavlyemlyglppfysrdvaemydnilnkplqlkpgisvaalelleellekdrk  240

         vdwwclgavlyemlyglppfys+dvaemyd+il++plql++g +vaa+++l++ll+kd+k

Q: 216   VDWWCLGAVLYEMLYGLPPFYSQDVAEMYDKILHQPLQLRTGKTVAACDILQGLLQKDQK  275

         ************************************************************

S: 241   krlgakedfleiknhvff  258

         krlgak+dfleiknh+ff

Q: 276   KRLGAKADFLEIKNHMFF  293

         *****************9

Domain Sequence
(FASTA)

FDFLKVIGKG SYGKVLLAKR KSDGKFYAVK VLQKKTILHR KEQRHIMAER NVLLKNVKHP 60

FLVGLHYSFQ TPEKLYFVLD YVNGGEVFFH LQQERSFPEP RARFYAAEVA SAIGYLHSLN 120

IVYRDLKPEN ILLDSQGHIV LTDFGLCKEG IEPEGTTSTF CGTPEYLAPE VLRKQPYDRT 180

VDWWCLGAVL YEMLYGLPPF YSQDVAEMYD KILHQPLQLR TGKTVAACDI LQGLLQKDQK 240

KRLGAKADFL EIKNHMFF 258

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Xenopus tropicalis"; ?>Saccharomyces cerevisiae"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR000961	; AGC-kinase_C.
IPR011009	; Kinase-like_dom.
IPR017892	; Pkinase_C.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069	; Pkinase; 1.
PF00433	; Pkinase_C; 1.

SMARTs

SM00133	; S_TK_X; 1.
SM00220	; S_TKc; 1.

Prosites

PS51285	; AGC_KINASE_CTER; 1.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013