EKS-LAC-00449

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-LAC-00449

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/ULK	341.5	4.2E-102	13	269	257

Status

Unreviewed

Ensembl Protein

ENSLACP00000001892

UniProt Accession

H2ZWX1;

Protein Name

Protein Synonyms/Alias

Gene Name

ULK3

Gene Synonyms/Alias

ULK3;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSLACG00000001690	ENSLACP00000001892	ENSLACT00000001905

Organism

Latimeria chalumnae

Functional Description

Protein Length

471

Protein Sequence
(FASTA)

MAAGFAPPKL DEFILTERLG SGTYATVYKA YRKKNSREVV AIKCVHKKSL NKASVENLLT 60

EIEILKAIRH PHIVELKDFQ WDNENIYLIM EFCAGGDLSR FIRSRRMLPE HVGRRFLQQL 120

ASALLFLHER NISHLDLKPQ NILLSSPDRP HLKLADFGFA QYMSPWDEKH VLRGSPLYMA 180

PEMVCHNQYD ARVDLWSVGV ILYEALFGRP PFASKSFAEL EDKIRSDKRI ELPPGARVSR 240

DCKDLLLRLL ERDPLHRIMF EEFFTHPFVD LDHMPSAESL EKATSLVLEA VKKDQAGDHS 300

TALSFYCKSL EYFVPALHYE TDARRKEALR SKVNQYISRA EELKALVASD NKANFERAKS 360

ARDLLKELSK DKPRLLAALE MASAALLMEE EGKEYADALD LYQQSLGELL LMLAGEPQGR 420

RRDLLHEEIK TLMSRAEYLK AHLKMKESQT EAASMDRYQL ADSVKSSKYF M 471

Nucleotide Sequence
(FASTA)

ATGGCTGCTG GGTTTGCTCC TCCTAAGCTG GACGAGTTCA TCCTGACAGA AAGGCTGGGC 60

AGTGGCACCT ATGCAACTGT TTACAAAGCA TATAGGAAGA AAAACAGTCG GGAAGTGGTG 120

GCAATCAAAT GCGTGCACAA GAAGAGTTTG AACAAAGCCT CAGTGGAGAA CCTTCTGACT 180

GAGATTGAGA TACTGAAGGC CATCCGCCAT CCACACATTG TGGAGCTCAA GGACTTTCAG 240

TGGGACAATG AAAACATTTA CCTGATCATG GAGTTCTGTG CGGGCGGAGA TCTTTCCCGC 300

TTTATCCGCA GTCGCAGGAT GCTCCCGGAG CACGTGGGTC GCCGGTTCCT TCAGCAGCTG 360

GCCTCGGCTT TGTTGTTTCT GCATGAGCGA AACATTTCAC ACCTCGACTT AAAGCCGCAG 420

AACATCCTGC TCAGCTCCCC GGACAGGCCT CACCTGAAGC TCGCTGATTT TGGTTTTGCC 480

CAGTACATGT CCCCTTGGGA TGAGAAGCAT GTTTTAAGGG GCTCCCCGCT CTACATGGCT 540

CCTGAGATGG TGTGTCATAA TCAGTATGAT GCCAGGGTCG ACCTATGGTC TGTAGGAGTC 600

ATTCTTTATG AGGCTTTGTT CGGACGGCCA CCTTTTGCTT CAAAGTCATT TGCAGAGCTG 660

GAAGACAAGA TCCGTAGCGA CAAGCGTATT GAGCTCCCGC CTGGGGCCCG TGTTTCCCGG 720

GACTGTAAGG ACCTGCTGCT TCGACTGCTG GAGAGGGACC CCCTGCACCG GATAATGTTC 780

GAGGAATTCT TTACCCATCC CTTTGTTGAC CTGGATCACA TGCCCAGTGC AGAATCTCTT 840

GAAAAGGCTA CCTCGTTAGT GTTGGAGGCG GTGAAGAAGG ACCAGGCAGG CGATCATTCA 900

ACTGCGCTAT CTTTTTACTG TAAATCCTTG GAGTACTTTG TCCCTGCTTT GCACTATGAA 960

ACTGATGCTC GCCGCAAGGA GGCCCTCCGG TCAAAGGTGA ACCAGTACAT TTCAAGAGCA 1020

GAAGAGCTTA AAGCACTTGT AGCATCAGAC AACAAAGCCA ATTTCGAGCG AGCAAAGTCT 1080

GCCCGGGACC TTTTAAAAGA GCTGTCAAAA GATAAGCCTC GCCTCTTGGC AGCACTGGAA 1140

ATGGCCTCTG CAGCTTTGCT AATGGAGGAG GAAGGAAAGG AATATGCTGA CGCCTTGGAC 1200

CTTTACCAGC AGAGTCTCGG GGAGCTGCTG CTCATGTTAG CTGGTGAGCC TCAGGGAAGA 1260

CGACGGGATC TGCTTCACGA GGAGATTAAA ACTCTAATGA GCAGAGCTGA GTATCTCAAA 1320

GCGCATCTTA AGATGAAGGA GTCTCAAACT GAAGCTGCAT CCATGGACAG GTATCAACTA 1380

GCAGACTCTG TCAAGAGCAG TAAGTATTTC ATG 1413

Domain Profile

S: 1     ysleeeiGkGsfavvykgrlrkktsqvvAikvvekkkl.kkslenlekeikilkelkhen  59

         ++l+e++G+G++a+vyk++ +k++++vvAik+v+kk+l k+s+enl +ei+ilk ++h++

Q: 13    FILTERLGSGTYATVYKAYRKKNSREVVAIKCVHKKSLnKASVENLLTEIEILKAIRHPH  72

         7899**********************************999*******************

S: 60    ivalldveetskevylvmeycaggdLakllkqkkeLsedtvreflqqlasalkaLhskki  119

         iv+l+d++++++++yl+me+caggdL++++++++ L+e++ r+flqqlasal +Lh+++i

Q: 73    IVELKDFQWDNENIYLIMEFCAGGDLSRFIRSRRMLPEHVGRRFLQQLASALLFLHERNI  132

         ************************************************************

S: 120   vhrDlkPqniLlsyadakkelkkvtlkladFglarvlkeesmaatlkGsplYmaPEvvke  179

         +h DlkPqniLls      + +  +lkladFg+a++++ +++++ l+GsplYmaPE+v++

Q: 133   SHLDLKPQNILLS------SPDRPHLKLADFGFAQYMSPWDEKHVLRGSPLYMAPEMVCH  186

         *************......78999************************************

S: 180   qqydakaDlWSiGtilyellvGkpPfaaesiseLvekiekndvleppipkeisselkdll  239

         +qyda++DlWS+G+ilye+l+G+pPfa++s+ eL+ ki++++ +e+p  +++s+++kdll

Q: 187   NQYDARVDLWSVGVILYEALFGRPPFASKSFAELEDKIRSDKRIELPPGARVSRDCKDLL  246

         ************************************************************

S: 240   qsLLqrdpkkRisfeelfahpfl  262

          +LL+rdp +Ri fee+f+hpf+

Q: 247   LRLLERDPLHRIMFEEFFTHPFV  269

         *********************96

Domain Sequence
(FASTA)

FILTERLGSG TYATVYKAYR KKNSREVVAI KCVHKKSLNK ASVENLLTEI EILKAIRHPH 60

IVELKDFQWD NENIYLIMEF CAGGDLSRFI RSRRMLPEHV GRRFLQQLAS ALLFLHERNI 120

SHLDLKPQNI LLSSPDRPHL KLADFGFAQY MSPWDEKHVL RGSPLYMAPE MVCHNQYDAR 180

VDLWSVGVIL YEALFGRPPF ASKSFAELED KIRSDKRIEL PPGARVSRDC KDLLLRLLER 240

DPLHRIMFEE FFTHPFV 257

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dasypus novemcinctus"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR007330	; MIT.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF04212	; MIT; 2.
PF00069	; Pkinase; 1.

SMARTs

SM00745	; MIT; 2.
SM00220	; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013