EPS-LAC-00050

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-LAC-00050

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPP/PP7	212.7	7.3E-63	113	268	156

Status

Unreviewed

Ensembl Protein

ENSLACP00000002812

UniProt Accession

H2ZZJ1;

Protein Name

Serine/threonine-protein phosphatase

Protein Synonyms/Alias

Gene Name

PPEF2

Gene Synonyms/Alias

PPEF2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSLACG00000002515	ENSLACP00000002812	ENSLACT00000002834

Organism

Latimeria chalumnae

Functional Description

Protein Length

700

Protein Sequence
(FASTA)

AIKAAVLIQR WYRQYVARME VRRRCTWTIF QSIEYAGEQD QIKLYNFFNY LMDHFTPSSS 60

NERNLISHIF SEEENLRDTE LVKYCDHESI EAPDCYSGPQ LSFPLQPAHA AALVEAFKRR 120

QHLHAHYVFQ LLQETRKHLK QLPNINRVST CYSKEITVCG DLHGKLDDLF LIFYKNGLPS 180

PEQTYVFNGD YVDRGKHSME ILLILFAFLL VYPKNVHLNR GNHEDYIMNL RYGFTKEVMQ 240

KYKVCFISLF CFYSSNFFSH LLCLSMHEGR VWGVSLLWKM KRRPVEYKST TKEMGASYQE 300

KKKSCLELFL ACFSLPMLPA DILHAPFNAC RIESFEPSQA KRFSAFRCLM CTCDMTIMHE 360

SYCNMVLKIR NVVQSPKKGG ILAYSITRKT THKSKNKRPG KREILNESSL IWKKVVDILW 420

SDPMHQDGCI PNIVRGGGCY FGPDVTEKVL QKHSLQLLIR SHECKQEGYE FCHNRKVLTI 480

FSASNYYEVG SNRGAYVKLG PDLSPHFVQY QANRTIRKLT MRQRLSGVES SALRALREKL 540

FAHKSDLISI FKHYDKNNLG RISINDWATA VESVLHLGLP WRVLRSQLVY HAPEGLLEYQ 600

SWFDDLVIEQ PIKEHIQPSL LEALYQNRSN LETIFRIIDS DNSGLISFEE FCQTWKLLSS 660

HLNIEVSDKA ICDLARSIDF NKDGNIDINE FLEAFRLVDK 700

Nucleotide Sequence
(FASTA)

GCTATTAAAG CTGCTGTTCT GATTCAGAGA TGGTACCGAC AGTACGTCGC TCGAATGGAA 60

GTGCGCAGGC GCTGCACATG GACTATCTTT CAGTCCATTG AGTACGCAGG AGAGCAGGAC 120

CAGATCAAGC TGTACAATTT CTTCAACTAC CTCATGGACC ACTTTACTCC ATCCAGCAGT 180

AATGAAAGGA ACCTGATTTC ACACATTTTC AGCGAGGAGG AAAACTTAAG AGACACAGAA 240

CTAGTTAAGT ACTGTGACCA TGAGTCCATT GAGGCACCAG ACTGCTATTC CGGACCCCAA 300

CTCTCTTTTC CTCTTCAGCC GGCTCATGCA GCTGCCTTAG TGGAAGCCTT CAAACGGAGG 360

CAACACCTCC ATGCTCACTA TGTCTTCCAA CTTCTGCAAG AAACCAGAAA GCACTTGAAA 420

CAGCTGCCAA ACATCAACCG AGTGTCTACC TGCTACAGCA AGGAGATTAC TGTCTGTGGA 480

GATCTGCATG GGAAGTTAGA TGACCTATTT TTGATATTCT ACAAGAATGG TCTCCCTTCT 540

CCAGAACAAA CATATGTGTT TAATGGTGAT TATGTGGACA GAGGCAAACA TTCCATGGAG 600

ATATTGCTGA TTCTGTTTGC ATTCTTGCTG GTTTATCCCA AAAATGTGCA TTTAAACAGG 660

GGCAATCATG AAGACTATAT TATGAACTTA AGATATGGTT TTACAAAGGA AGTAATGCAA 720

AAGTACAAGG TATGTTTTAT TTCTTTGTTT TGTTTTTATA GTTCTAATTT TTTCAGCCAT 780

CTCCTCTGTT TAAGTATGCA TGAGGGCAGA GTGTGGGGTG TCTCTCTATT GTGGAAAATG 840

AAAAGAAGGC CTGTGGAGTA TAAAAGTACA ACAAAAGAGA TGGGTGCTTC CTATCAAGAG 900

AAAAAAAAAT CCTGCCTAGA ACTTTTCCTT GCCTGTTTCT CTTTGCCTAT GCTTCCAGCA 960

GACATTCTTC ATGCACCCTT TAATGCATGC AGAATAGAGT CTTTTGAACC ATCACAAGCA 1020

AAAAGGTTTT CTGCTTTCAG ATGTTTAATG TGTACATGTG ACATGACTAT AATGCACGAG 1080

TCATACTGCA ATATGGTTTT GAAAATCAGA AACGTGGTTC AATCCCCCAA AAAAGGGGGG 1140

ATACTAGCTT ACAGTATAAC TCGCAAAACA ACACACAAAA GCAAAAATAA GCGGCCTGGA 1200

AAAAGAGAAA TCTTGAATGA ATCCAGCTTG ATCTGGAAAA AGGTTGTTGA CATTTTATGG 1260

AGTGACCCAA TGCACCAGGA CGGCTGCATC CCCAACATAG TCCGAGGAGG CGGCTGCTAC 1320

TTCGGGCCAG ATGTTACGGA GAAGGTCCTA CAGAAGCACA GCCTGCAGCT CTTAATCCGT 1380

TCTCATGAGT GCAAGCAGGA GGGCTATGAG TTCTGCCATA ACAGAAAGGT CCTGACCATC 1440

TTCTCTGCCT CAAATTACTA TGAAGTTGGC AGTAACAGGG GAGCCTATGT GAAGCTGGGC 1500

CCGGACCTCA GCCCACATTT TGTCCAGTAC CAAGCCAACA GAACAATACG CAAGTTAACT 1560

ATGAGACAAA GACTCAGCGG AGTGGAGAGC TCAGCGCTAA GGGCCCTAAG AGAGAAGCTA 1620

TTTGCTCACA AATCAGACCT GATCAGCATT TTTAAGCACT ATGACAAGAA TAATCTTGGT 1680

AGAATATCCA TCAACGATTG GGCAACTGCT GTGGAGTCAG TCTTGCATTT GGGTCTGCCA 1740

TGGCGGGTCC TCCGATCTCA GTTAGTGTAC CATGCTCCAG AGGGTTTGCT GGAGTACCAG 1800

TCATGGTTTG ATGACCTTGT AATAGAACAA CCCATCAAAG AGCACATACA ACCCAGTCTC 1860

TTGGAAGCAC TCTACCAAAA CAGATCCAAC TTGGAGACTA TCTTCAGAAT TATAGACAGT 1920

GACAACTCAG GGCTCATCTC CTTTGAAGAG TTTTGTCAAA CCTGGAAGCT CCTTAGTTCT 1980

CACCTTAATA TCGAAGTCAG TGACAAAGCT ATCTGCGATC TAGCCCGCAG TATTGACTTC 2040

AACAAAGATG GCAACATCGA CATTAATGAG TTCCTGGAAG CATTTCGCCT TGTGGACAAG 2100

Domain Profile

S: 4     llevfkkkrilhakyvlevlfeakkvlkqlpnishvstavskevtvvGdlhGklddlllv  63

         l+e+fk+++ lha+yv ++l+e++k lkqlpni++vst+ ske+tv+GdlhGklddl+l+

Q: 113   LVEAFKRRQHLHAHYVFQLLQETRKHLKQLPNINRVSTCYSKEITVCGDLHGKLDDLFLI  172

         89**********************************************************

S: 64    lkknGlPsernpyvfnGdfvdrGkrglevllvllslflvfPnavylnrGnhedkvmnary  123

         ++knGlPs +++yvfnGd+vdrGk+++e+ll+l ++ lv+P++v+lnrGnhed +mn+ry

Q: 173   FYKNGLPSPEQTYVFNGDYVDRGKHSMEILLILFAFLLVYPKNVHLNRGNHEDYIMNLRY  232

         ************************************************************

S: 124   Gfekevlskykrkgkrilril.eevyewlPlgsivd  158

         Gf+kev++kyk     ++ +   +++  l   s+ +

Q: 233   GFTKEVMQKYKVCFISLFCFYsSNFFSHLLCLSMHE  268

         **********98776666654134555555555555

Domain Sequence
(FASTA)

LVEAFKRRQH LHAHYVFQLL QETRKHLKQL PNINRVSTCY SKEITVCGDL HGKLDDLFLI 60

FYKNGLPSPE QTYVFNGDYV DRGKHSMEIL LILFAFLLVY PKNVHLNRGN HEDYIMNLRY 120

GFTKEVMQKY KVCFISLFCF YSSNFFSHLL CLSMHE 156

Keyword

Calcium; Complete proteome; Hydrolase; Iron; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005509	; F:calcium ion binding
GO:0004721	; F:phosphoprotein phosphatase activity

KEGG

InterPros

IPR011992	; EF-hand-like_dom.
IPR018247	; EF_Hand_1_Ca_BS.
IPR018249	; EF_HAND_2.
IPR002048	; EF_hand_Ca-bd.
IPR000048	; IQ_motif_EF-hand-BS.
IPR004843	; Metallo_PEstase_dom.
IPR013235	; PPP_dom.
IPR006186	; Ser/Thr-sp_prot-phosphatase.

Pfam

PF00149	; Metallophos; 1.
PF08321	; PPP5; 1.

SMARTs

SM00054	; EFh; 3.
SM00015	; IQ; 1.
SM00156	; PP2Ac; 1.

Prosites

PS00018	; EF_HAND_1; 2.
PS50222	; EF_HAND_2; 3.
PS50096	; IQ; 1.
PS00125	; SER_THR_PHOSPHATASE; 1.

Prints

PR00114

; STPHPHTASE.

Created Date

20-Feb-2013