EKS-LAC-00249

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-LAC-00249

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
AGC/PDK1	405.0	1.9E-121	90	350	261

Status

Unreviewed

Ensembl Protein

ENSLACP00000023654

UniProt Accession

H3A0R9;

Protein Name

Protein Synonyms/Alias

Gene Name

PDPK1

Gene Synonyms/Alias

PDPK1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSLACG00000002897	ENSLACP00000023654	ENSLACT00000025431
ENSLACG00000002897	ENSLACP00000003240	ENSLACT00000003270

Organism

Latimeria chalumnae

Functional Description

Protein Length

563

Protein Sequence
(FASTA)

MAGTTSQIYD AVPIQSSVVI CSCPSPSMVR NKPDSSVPLP IGGSSNSQGS TMEGTAAETR 60

SNSNSSQHSA QRQQSTQQSQ QPRKKRPEDF KFGKILGEGS FSTVVLAREL ASGKEYAIKI 120

LEKRHIIKEN KVPCVTREKD VMSRLDHPFF VKLYFTFQDY EKLYFGLSYA KNGELLKYIR 180

KIGSFDETCT RFYSAETVSA LEYLHGVGII HRDLKPENIL LNEDMHIQIT DFGTAKVLSS 240

DSKQARANSF VGTAQYVSPE LLTEKSACKS SDLWALGCII YQLVAGLPPF RAGNEYLIFQ 300

KIIKLEYEFP EKFFPKAKDL VKQLLVLDST KRLGCEEMGG YEPLTAHPFF ESINWENLHL 360

QTPPKLTAYL PAMSEDDEDC YGNYDDLLSQ FGCMQVATST SSQLQSAVEP TQPQRSGSNI 420

EHYIHGLDNN SFELDLQFSE EEKRLLLERQ ANVNQWHQFV ENNLILKMGP VDKRKGLFAR 480

RRQLLLTEGP HLYYVDPVNK VLKGEIPWSL ELRPEAKNFK TFFVHTPNRT YYLMDPSGNA 540

HKWCKKIKEV WQQRYQNHQN AGI 563

Nucleotide Sequence
(FASTA)

ATGGCAGGAA CTACTAGCCA GATTTATGAT GCTGTTCCTA TTCAGTCCAG TGTGGTTATA 60

TGTTCCTGCC CATCTCCATC AATGGTAAGA AATAAGCCTG ATTCCAGTGT GCCACTTCCC 120

ATTGGAGGCT CCAGTAACAG CCAGGGTTCT ACCATGGAAG GCACTGCAGC TGAAACAAGG 180

TCCAATTCAA ACTCCTCACA ACATTCGGCA CAGCGGCAAC AGTCCACCCA GCAATCCCAA 240

CAACCCAGAA AGAAAAGACC AGAAGATTTC AAGTTTGGAA AAATTCTTGG TGAAGGGTCT 300

TTCTCAACGG TGGTTTTGGC ACGTGAATTG GCATCTGGAA AAGAGTACGC TATTAAAATT 360

CTAGAGAAAC GTCATATCAT AAAAGAAAAT AAGGTACCAT GTGTGACCCG GGAGAAGGAT 420

GTAATGTCTC GTCTGGATCA CCCTTTCTTT GTAAAACTCT ACTTCACTTT TCAAGATTAT 480

GAAAAGCTAT ATTTTGGCCT TAGCTACGCC AAAAATGGGG AACTCCTGAA GTACATTCGC 540

AAAATAGGTT CATTTGATGA GACCTGCACA AGATTTTATT CCGCTGAAAC TGTGTCAGCA 600

TTAGAATACT TGCATGGGGT GGGGATTATT CACAGGGACC TTAAGCCAGA AAACATTTTA 660

TTGAATGAGG ATATGCACAT TCAAATTACA GACTTTGGAA CAGCAAAAGT ATTATCCTCA 720

GATAGTAAAC AAGCAAGGGC AAATTCATTT GTAGGAACAG CACAATATGT TTCTCCTGAA 780

TTGCTGACAG AGAAATCTGC TTGCAAAAGT TCCGACCTCT GGGCCCTTGG CTGTATAATA 840

TACCAACTTG TAGCTGGATT ACCACCCTTT AGAGCTGGAA ATGAATACCT TATATTCCAG 900

AAGATCATTA AGCTGGAGTA TGAATTCCCA GAAAAATTTT TCCCTAAGGC AAAAGATCTT 960

GTAAAACAGC TATTGGTATT AGATTCCACA AAGCGGTTAG GCTGTGAAGA AATGGGAGGG 1020

TATGAACCTC TTACAGCTCA TCCATTTTTC GAGTCTATTA ATTGGGAGAA TCTACATCTT 1080

CAGACTCCTC CAAAACTCAC AGCCTACTTA CCAGCCATGT CAGAGGATGA TGAAGATTGC 1140

TATGGAAATT ATGATGATCT TCTTAGCCAG TTTGGTTGTA TGCAAGTGGC AACTTCAACC 1200

TCCTCCCAGT TACAGTCTGC AGTGGAGCCA ACTCAACCCC AGCGGTCGGG CAGTAACATT 1260

GAGCACTACA TTCATGGCCT TGACAATAAT TCATTTGAGC TAGATCTACA GTTTTCAGAA 1320

GAAGAGAAAA GGCTACTGCT AGAAAGACAG GCTAATGTAA ACCAGTGGCA CCAGTTTGTA 1380

GAAAACAATT TAATTCTAAA AATGGGTCCA GTGGACAAAA GAAAGGGATT GTTTGCACGT 1440

CGGCGCCAGT TACTTTTAAC TGAAGGACCA CATCTTTACT ACGTGGACCC AGTGAACAAA 1500

GTTCTGAAAG GGGAGATTCC ATGGTCCCTT GAACTACGTC CAGAAGCCAA GAACTTCAAA 1560

ACATTTTTTG TTCATACACC TAATCGGACG TATTACCTGA TGGATCCCAG TGGAAATGCT 1620

CACAAATGGT GCAAAAAGAT CAAAGAAGTT TGGCAACAGA GATACCAGAA CCACCAAAAT 1680

GCTGGCATAT AA 1692

Domain Profile

S: 1     fkfekelgeGsystvvlarekeskkeyaikvlekryiikekkvkyvtrekevlaklnehp  60

         fkf+k+lgeGs+stvvlare++s keyaik+lekr+iike+kv+ vtrek+v+++l +hp

Q: 90    FKFGKILGEGSFSTVVLARELASGKEYAIKILEKRHIIKENKVPCVTREKDVMSRL-DHP  148

         89******************************************************.9**

S: 61    givkLyatfqDeeslyfvleyakkGdllellkkvgsfdeactryyaaellsaleflhkkg  120

         ++vkLy+tfqD e+lyf l+yak+G+ll++++k+gsfde+ctr+y+ae +sale+lh  g

Q: 149   FFVKLYFTFQDYEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYSAETVSALEYLHGVG  208

         ************************************************************

S: 121   iihrDlkpeniLldkdgkilitDfGsakvlepklkedskkeeeesarsksfvGtaeyvsP  180

         iihrDlkpeniLl++d++i+itDfG+akvl++++k+         ar++sfvGta+yvsP

Q: 209   IIHRDLKPENILLNEDMHIQITDFGTAKVLSSDSKQ---------ARANSFVGTAQYVSP  259

         ******************************777776.........9**************

S: 181   elLtdsevskssDlWalgcilyqllaGkpPfraeneylifkkilkleyafpegfpekakd  240

         elLt+++++kssDlWalgci+yql+aG+pPfra neylif+ki+kley+fpe+f++kakd

Q: 260   ELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYEFPEKFFPKAKD  319

         ************************************************************

S: 241   lveklLvkdakerltlee......ikahkff  265

         lv++lLv d ++rl++ee      + ah+ff

Q: 320   LVKQLLVLDSTKRLGCEEmggyepLTAHPFF  350

         ******************9999999*****9

Domain Sequence
(FASTA)

FKFGKILGEG SFSTVVLARE LASGKEYAIK ILEKRHIIKE NKVPCVTREK DVMSRLDHPF 60

FVKLYFTFQD YEKLYFGLSY AKNGELLKYI RKIGSFDETC TRFYSAETVS ALEYLHGVGI 120

IHRDLKPENI LLNEDMHIQI TDFGTAKVLS SDSKQARANS FVGTAQYVSP ELLTEKSACK 180

SSDLWALGCI IYQLVAGLPP FRAGNEYLIF QKIIKLEYEF PEKFFPKAKD LVKQLLVLDS 240

TKRLGCEEMG GYEPLTAHPF F 261

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR011993	; PH_like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013