EKS-LAC-00065

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-LAC-00065

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDK	374.9	2.7E-112	563	855	293

Status

Unreviewed

Ensembl Protein

ENSLACP00000003341

UniProt Accession

H3A120;

Protein Name

Protein Synonyms/Alias

Gene Name

CDK13

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSLACG00000002989	ENSLACP00000003341	ENSLACT00000003371

Organism

Latimeria chalumnae

Functional Description

Protein Length

1360

Protein Sequence
(FASTA)

REKRRSFSRH RRRKHNKELS SSEKRSVFEK DGEITTLVEY DDVSSQSEGF SGSPFFQVGL 60

QAGHPIGQAD RQHGNQEKRS RKEHHGKEHH SSSRNKEREH RRKDHHHRVG DPSKSRSTSR 120

HTKDGTKKRS TENSDSNGNR KTSSLSSTRK EKESKTQKHK SKLEKQPPLA YKEPPKAYRD 180

DREEPKPYKK KLSVSPSLRD ESPCAHNQSR RSPSFRSRRR SPSPSYYGTS PFSKRQRSPS 240

PYSRRRSPSY SRHSSYEQGE ISPSPYNRRR SRSPLSPDQR RTGKSRSRSP YSSRHSRSHS 300

RHRLSRSRSR HSSISPSTLT FKSSIAAELS KHKKARAAEA VKTSGKVSNT STPTKGSTSV 360

SAPQQSNTKD SKKTKPERTP SPTNAGTAKP EKAKAKATPS EAKQENHLPV DKNAKRAGLG 420

GKENKIAVVK EEPVTLQEKS KLPVASSLSV KEKEKNTAII TSTLPPLPLP PLLLEEQDGD 480

SSRESLPPKK EKRDMERKAR HSLMDLQFAP ELSGANYSLL RSPDGKKTPP QAYIKKRPKI 540

CGPRCGEIKE TEIDWGKRCV DKFDIIGIIG EGTYGQVYKA RDKDTGEMVA LKKVRLDNEK 600

EGFPITAIRE IKILRQLNHR SIINMKEIVT DKEDALDFKK DKGAFYLVFE YMDHDLMGLL 660

ESGLVYFNEN HIKSFMKQLM EGLDYCHKKN FLHRDIKCSN ILLNNRGQIK LADFGLARLY 720

SSEESRPYTN KVITLWYRPP ELLLGEERYT PAIDVWSCGC ILGELFTKKP IFQANQELAQ 780

LELISRICGS PCPAVWPDVI KLQCFNTMKP KKQYRRRLRE EFAFIPSAAL DLFDHMLALD 840

PSKRCTAEQA LQCEFLKDVD PSKMPPPDLP LWQDCHELWS KKRRRQKQMG IVDDATAAKV 900

PRKDLALSLD DSRNSTPQSI QPTQHKTQGS TSAGLENCTN QQLHFMEVVA FINLLILQYV 960

LCGSNCFIIT NNIVFYDQFG ITNILKINKS QGSHGSCEPP TSPGNPLLNK YRQANFGDEC 1020

RSINQLNNLI CVQALILKII AMFFNNIFWA KIESSKQFFG ALHKCPHFIN LLTFSIEDAE 1080

EEDPCKQPAP ISGPSPVNEH PWILPPDQRP PEPPEPPPLP ACEDLDYRTE QQPTAPASSG 1140

PDPHAGVKAA LLQLLAEHQA QEEAESPADY PMENSFRTAA DLEEFGSSSS FSTSKYGSDG 1200

FGGGPLCPGE RSSFIGNMDG SAFSLDSYHT SSSHVSAPQP PAFLEPFSGS VTGYGDSSYL 1260

SSGSMLFSGD KDHRFEYNHG PLPVLGNGGD PSVGLECTRP LPTKVHNYNY GSSVHENVGT 1320

SGPLLGHTWG SPAQGPGYPQ SYRGHINAPV IRGRGRGLPY 1360

Nucleotide Sequence
(FASTA)

CGAGAGAAAC GTCGCTCGTT TTCCCGGCAC AGAAGGCGCA AACACAACAA AGAACTGAGC 60

AGTAGCGAGA AGAGAAGTGT GTTTGAAAAA GATGGGGAGA TCACGACCCT TGTGGAATAT 120

GACGATGTGA GTTCTCAGTC TGAAGGATTT TCTGGCAGCC CCTTTTTTCA GGTTGGCCTT 180

CAAGCTGGGC ATCCGATCGG TCAAGCAGAT AGACAACACG GTAATCAGGA GAAGAGATCG 240

AGGAAAGAGC ACCACGGTAA AGAGCACCAT AGCAGCAGTA GGAATAAAGA AAGAGAGCAC 300

AGAAGGAAAG ATCATCACCA CAGGGTGGGG GACCCTTCAA AATCCAGGAG CACTAGTAGG 360

CACACCAAGG ATGGCACAAA GAAACGCAGC ACTGAAAACA GTGACAGCAA TGGCAATAGG 420

AAGACTTCCT CCCTTTCATC CACCAGGAAG GAGAAGGAAT CAAAGACTCA GAAGCATAAG 480

AGTAAACTAG AAAAACAACC TCCGTTGGCA TATAAGGAGC CTCCAAAAGC TTACAGAGAT 540

GACAGAGAAG AACCTAAGCC ATATAAGAAA AAACTGTCTG TAAGTCCCAG TTTGAGAGAT 600

GAAAGTCCAT GTGCACACAA CCAATCTAGG AGAAGCCCCA GTTTTAGGAG CAGAAGAAGA 660

TCACCTAGCC CATCTTATTA TGGAACTAGC CCCTTTTCTA AGCGGCAGAG ATCCCCAAGT 720

CCATACAGCA GGCGCAGATC TCCCAGCTAT AGCAGGCATA GTTCTTATGA ACAGGGAGAA 780

ATTTCTCCTA GTCCATACAA CAGACGTAGA TCAAGGAGCC CGTTGAGCCC TGATCAAAGG 840

AGAACAGGGA AGTCTCGGAG CAGAAGTCCA TATTCCTCAA GGCACTCCCG TTCTCACAGC 900

AGGCACCGAC TGTCCAGATC CCGCAGTCGT CACTCAAGCA TTTCTCCTAG TACTCTGACA 960

TTCAAAAGCA GCATCGCCGC TGAACTGAGC AAACACAAAA AGGCCAGAGC TGCTGAGGCA 1020

GTCAAGACCA GCGGAAAAGT GTCCAACACC TCCACGCCTA CCAAAGGAAG CACCAGTGTC 1080

AGTGCACCTC AACAGAGCAA TACGAAAGAT TCTAAGAAAA CCAAACCTGA GCGAACGCCA 1140

TCGCCCACCA ACGCTGGGAC TGCCAAACCC GAAAAGGCAA AAGCCAAGGC GACACCGTCA 1200

GAGGCAAAGC AGGAAAACCA TTTGCCTGTG GACAAAAACG CAAAGCGAGC GGGTCTAGGA 1260

GGAAAAGAGA ACAAAATAGC GGTAGTGAAG GAAGAGCCAG TAACACTACA AGAAAAAAGC 1320

AAACTTCCTG TAGCAAGTAG CCTCAGTGTA AAGGAGAAGG AGAAAAACAC AGCAATAATA 1380

ACATCAACAT TGCCACCTCT ACCCCTTCCT CCTTTGCTGC TTGAAGAACA GGATGGAGAC 1440

AGTTCAAGAG AGAGTCTTCC ACCAAAGAAG GAGAAGAGGG ATATGGAGAG AAAAGCCCGT 1500

CACTCACTTA TGGACCTCCA GTTTGCACCA GAGTTGTCAG GGGCAAATTA CTCCTTGCTG 1560

AGAAGCCCAG ATGGGAAGAA AACACCACCT CAGGCATACA TCAAGAAAAG ACCAAAAATT 1620

TGTGGACCCC GCTGTGGTGA AATAAAAGAA ACTGAAATTG ACTGGGGGAA ACGCTGTGTG 1680

GATAAGTTTG ACATTATTGG AATTATCGGA GAAGGCACTT ATGGACAAGT CTACAAAGCC 1740

AGGGACAAAG ATACAGGTGA AATGGTAGCT CTAAAGAAAG TACGCTTAGA CAATGAAAAG 1800

GAAGGTTTTC CAATTACTGC TATTCGAGAA ATTAAGATCT TACGGCAACT GAACCACCGG 1860

AGCATCATCA ATATGAAGGA GATTGTGACA GATAAAGAGG ATGCGCTGGA TTTTAAAAAA 1920

GATAAAGGTG CTTTTTACCT GGTGTTTGAA TACATGGACC ATGATTTGAT GGGATTATTG 1980

GAATCTGGAT TAGTATATTT TAATGAAAAT CATATTAAAT CGTTCATGAA GCAACTGATG 2040

GAAGGATTGG ACTACTGCCA TAAGAAAAAC TTTTTGCATA GAGATATTAA GTGTTCCAAC 2100

ATTCTACTAA ACAACAGGGG GCAGATTAAA CTTGCTGATT TTGGTCTTGC TAGACTTTAT 2160

AGTTCTGAGG AGAGCCGTCC ATATACCAAT AAAGTTATTA CTTTGTGGTA TCGGCCTCCT 2220

GAACTACTGC TTGGAGAGGA GCGATATACA CCGGCCATTG ATGTCTGGAG TTGTGGATGT 2280

ATTCTTGGTG AGCTTTTTAC TAAAAAGCCA ATCTTTCAGG CAAACCAGGA ATTGGCTCAG 2340

TTAGAACTCA TCAGTCGTAT ATGTGGTAGC CCGTGTCCGG CTGTATGGCC TGACGTGATT 2400

AAGCTACAAT GTTTTAACAC AATGAAACCA AAGAAGCAAT ATCGACGTAG ACTGAGAGAA 2460

GAATTTGCTT TCATTCCTTC AGCTGCATTA GATCTGTTTG ATCACATGCT AGCATTAGAC 2520

CCCAGCAAGC GCTGCACTGC TGAACAAGCT CTCCAGTGTG AGTTCTTGAA AGATGTGGAT 2580

CCTTCCAAAA TGCCTCCACC GGACCTTCCC CTGTGGCAGG ATTGCCATGA GCTCTGGAGC 2640

AAAAAACGCA GAAGACAGAA GCAAATGGGA ATTGTTGATG ATGCAACTGC TGCCAAAGTC 2700

CCAAGGAAGG ACTTGGCTTT AAGCTTGGAT GACAGCAGGA ACAGTACTCC TCAAAGCATA 2760

CAACCTACAC AACATAAAAC TCAGGGCAGT ACCAGTGCTG GACTAGAAAA TTGCACCAAC 2820

CAGCAACTTC ACTTTATGGA GGTGGTTGCT TTTATTAATT TACTCATATT ACAGTATGTA 2880

CTGTGTGGCA GTAACTGCTT TATAATTACA AATAATATAG TGTTTTATGA TCAATTTGGT 2940

ATTACAAATA TTTTAAAAAT AAACAAAAGT CAGGGTTCAC ATGGATCCTG TGAGCCACCC 3000

ACAAGTCCTG GAAATCCTCT TTTGAATAAA TACAGGCAGG CCAATTTTGG GGATGAGTGC 3060

AGGTCCATCA ACCAACTAAA TAATTTGATT TGTGTTCAGG CTTTAATTTT GAAGATAATA 3120

GCAATGTTTT TTAATAACAT TTTCTGGGCC AAGATTGAAA GTTCAAAACA GTTCTTTGGG 3180

GCTTTACATA AATGTCCTCA TTTCATAAAC CTCTTAACCT TTTCTATTGA AGATGCAGAA 3240

GAAGAGGATC CTTGCAAGCA GCCAGCTCCC ATTTCAGGGC CGTCCCCTGT GAATGAGCAT 3300

CCTTGGATCT TACCTCCCGA TCAGCGTCCT CCTGAACCTC CAGAGCCGCC ACCACTGCCT 3360

GCCTGTGAAG ATCTAGACTA CCGGACTGAG CAGCAGCCCA CTGCTCCTGC CTCTTCTGGG 3420

CCAGATCCTC ATGCTGGAGT CAAGGCTGCT CTGCTTCAGC TTCTCGCTGA GCACCAAGCT 3480

CAAGAGGAAG CAGAGAGCCC TGCGGACTAT CCAATGGAAA ATTCTTTCAG AACTGCTGCA 3540

GACTTGGAAG AATTTGGATC GTCATCGTCA TTTTCCACGT CGAAATATGG TAGTGATGGA 3600

TTTGGAGGTG GTCCTCTGTG TCCAGGAGAG CGAAGCAGCT TCATTGGAAA CATGGACGGT 3660

TCAGCGTTCT CTCTTGATAG TTATCATACT AGTTCATCTC ATGTTAGTGC ACCACAACCT 3720

CCAGCATTTT TAGAGCCATT CTCTGGGTCA GTGACTGGAT ATGGAGATAG CAGTTACCTT 3780

AGTAGTGGTT CTATGCTGTT CAGTGGAGAT AAGGACCACC GGTTTGAATA TAATCATGGC 3840

CCTTTACCGG TGTTGGGAAA CGGTGGTGAT CCTTCTGTTG GGCTAGAATG TACTCGCCCT 3900

TTGCCAACAA AGGTACATAA CTATAACTAT GGAAGCAGTG TACATGAAAA TGTTGGTACC 3960

AGTGGTCCTC TCCTCGGACA CACCTGGGGA TCTCCTGCAC AAGGACCTGG TTACCCCCAA 4020

AGCTATAGAG GGCACATTAA TGCACCAGTA ATAAGAGGAA GAGGCAGAGG ATTACCATAT 4080

TGA 4083

Domain Profile

S: 1     yeklekigeGtygkvykakdketgevvAlKkirlekekegvpitalrEisllkelkhkni  60

         ++ +  igeGtyg+vyka+dk+tge+vAlKk+rl++ekeg+pita+rEi++l++l+h+ i

Q: 563   FDIIGIIGEGTYGQVYKARDKDTGEMVALKKVRLDNEKEGFPITAIREIKILRQLNHRSI  622

         667889******************************************************

S: 61    vkLlevva.........kdkkklyLvfefleqdLkkllkkkkkkklsleevkslllqlle  111

         ++++e+v+         kdk  +yLvfe++++dL+ ll++    +++++++ks+++ql+e

Q: 623   INMKEIVTdkedaldfkKDKGAFYLVFEYMDHDLMGLLESGLV-YFNENHIKSFMKQLME  681

         ****************8899********************999.****************

S: 112   glaylHsnkilHRDlKpqNlLiskegklklaDfGlarafssplk.tytkevvTlwYraPe  170

         gl+y+H++++lHRD+K++N+L++++g++klaDfGlar +ss+++  yt++v+TlwYr+Pe

Q: 682   GLDYCHKKNFLHRDIKCSNILLNNRGQIKLADFGLARLYSSEESrPYTNKVITLWYRPPE  741

         ***************************************7665527**************

S: 171   lLlgakeYstavDiWsvgcilaelltrkplfqgkseidqlerifkllgtpsekvwpevsk  230

         lLlg+++Y+ a+D+Ws+gcil el+t+kp+fq+++e  qle i++++g+p  +vwp+v k

Q: 742   LLLGEERYTPAIDVWSCGCILGELFTKKPIFQANQELAQLELISRICGSPCPAVWPDVIK  801

         ************************************************************

S: 231   lpeykksfpkkkkk.klkekvkklkekaldllekllaldpkkRisakealqhky  283

         l+ +++  pkk+++ +l+e++  + ++aldl++++laldp+kR++a++alq ++

Q: 802   LQCFNTMKPKKQYRrRLREEFAFIPSAALDLFDHMLALDPSKRCTAEQALQCEF  855

         *****7777777777******9999**************************988

Domain Sequence
(FASTA)

FDIIGIIGEG TYGQVYKARD KDTGEMVALK KVRLDNEKEG FPITAIREIK ILRQLNHRSI 60

INMKEIVTDK EDALDFKKDK GAFYLVFEYM DHDLMGLLES GLVYFNENHI KSFMKQLMEG 120

LDYCHKKNFL HRDIKCSNIL LNNRGQIKLA DFGLARLYSS EESRPYTNKV ITLWYRPPEL 180

LLGEERYTPA IDVWSCGCIL GELFTKKPIF QANQELAQLE LISRICGSPC PAVWPDVIKL 240

QCFNTMKPKK QYRRRLREEF AFIPSAALDL FDHMLALDPS KRCTAEQALQ CEF 293

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013