EPS-LAC-00019

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-LAC-00019

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
DSP/aDSP	119.9	9.0E-35	7	137	131

Status

Unreviewed

Ensembl Protein

ENSLACP00000003753

UniProt Accession

H3A282;

Protein Name

Protein Synonyms/Alias

Gene Name

DUSP27

Gene Synonyms/Alias

DUSP27;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSLACG00000003344	ENSLACP00000003753	ENSLACT00000003787

Organism

Latimeria chalumnae

Functional Description

Protein Length

996

Protein Sequence
(FASTA)

FCFPRSVAVN KARLKRMGIS HVLNTAHGTG VYTGTEFYAA MDIQYLGIEA DDFPNVDISK 60

HFRKAAEFMD EALLTYKGKI LVNSVMGISR SATLIAAYLM IFHHKTIMEA LMTIRKRRPI 120

SPNEGFLKQL RDLNESLLEE RGISYLENSD DDGEEEDTGS IMGAKVHSIM VEEEDDMTSV 180

MGSVMSSAAK ASEASKQPTL IDEDEEEMLY NEWRQRQGLP PKEPQTDKEE GKLPKFPEKG 240

EEDVKKMVRD WQCKNEKYQS EEWWHSKFMN DDEDGDSRMG RRRCSPSELS ELESVSSLDI 300

RILKEQLEAS GINKPGRGRS DSISTEDSTW DLWNQRLKDI EREALARCKS DYDDDDDGSM 360

ASLENEGRKK DVDEESTFSD TSSFFNFCKK NKEKLTPLER WKIKRIQFGW NKKNSEAQEG 420

KKPEGESKEG EGEEKSKLDV DLTAYQNWRL KRQKKLGNNS KDEFAELVKG EDAASSRRKQ 480

RRAELLERSK QTLEESQSLC GWETESAMSG SIPLSTFLPN MSARSATDDT ASMLSMQSNR 540

SSLSQARSNS GLPQTPLPNL LVGPDDTVSL ASIQNWIANV VTETIAQKQN EMMLQAQPPS 600

AISDSSRTSN LLRGTEDDKI SLLSMQSDMS YGSSLLRQTD ARSTDTRSVM SCGSTSGLQS 660

GAFGARDKVT GTSKPMYSLF VDDVDLKKLN RKEKEMKTEM RGKMFEYTKE KIASDNKRST 720

LFKKKKAKDD DEDSDFKEFT SGHAQYLNKS DTVSNISGCC ANLGTVSTES FSDIDKWLSS 780

VKSPARAPKL DGSEKTNLGY TDSSYQKGFE SKTSDFRHSR STAGELRSTS SSEVRENGFS 840

TSSRQVLTAT EAERKPSHRP KAAEMTGTRE ESTEPYFFSR TPDSTSNGES ESPKPTNSRL 900

RSPHHPAEKE ASEDQAVSDL GPKRKFASSF RERRGNDEAT TLSNNDEDED GTAHRSYRRR 960

PRANNETEGM DDDKLIAAWR SGKEEMRAKL QRLRKE 996

Nucleotide Sequence
(FASTA)

TTCTGCTTCC CCAGGAGTGT AGCAGTAAAC AAAGCCAGGC TGAAGAGGAT GGGTATCTCG 60

CACGTCCTCA ATACAGCCCA TGGCACCGGT GTTTACACAG GAACAGAGTT CTACGCCGCA 120

ATGGACATTC AATACCTGGG CATCGAGGCA GATGACTTCC CCAATGTAGA CATCTCCAAG 180

CACTTCCGGA AGGCTGCAGA GTTCATGGAT GAGGCCCTGC TAACCTACAA AGGTAAAATC 240

TTGGTTAACA GTGTAATGGG AATTAGTCGA TCTGCCACAC TCATTGCAGC TTATCTGATG 300

ATCTTTCACC ATAAGACAAT TATGGAGGCT TTGATGACCA TTCGCAAAAG ACGACCCATT 360

TCTCCAAATG AGGGCTTCCT GAAACAACTT CGAGACCTAA ATGAGAGCCT TCTGGAAGAA 420

CGCGGTATTT CCTATTTAGA AAACAGTGAT GATGATGGGG AGGAAGAAGA CACCGGGAGC 480

ATCATGGGAG CAAAAGTACA TTCCATTATG GTGGAAGAAG AAGACGACAT GACTAGTGTC 540

ATGGGTAGTG TAATGAGCTC AGCAGCTAAA GCAAGCGAGG CCTCCAAGCA GCCTACACTC 600

ATTGATGAAG ATGAGGAAGA AATGCTGTAT AATGAATGGA GACAAAGGCA AGGTCTGCCA 660

CCAAAGGAAC CACAAACAGA TAAAGAGGAA GGAAAGCTTC CCAAATTCCC AGAAAAGGGA 720

GAGGAGGATG TTAAAAAGAT GGTCAGAGAT TGGCAGTGCA AAAATGAAAA GTATCAGTCA 780

GAGGAGTGGT GGCATTCCAA GTTTATGAAT GATGATGAAG ATGGTGACTC TAGGATGGGT 840

AGAAGGAGGT GTTCTCCTAG TGAGCTTAGT GAGCTAGAAA GTGTTAGCAG CCTTGACATT 900

CGCATCTTAA AGGAGCAGTT GGAAGCCAGT GGCATAAACA AGCCTGGTAG AGGAAGAAGT 960

GACTCCATAT CTACAGAAGA TAGCACTTGG GATCTATGGA ACCAGCGACT AAAAGATATT 1020

GAAAGGGAAG CACTTGCAAG GTGCAAATCT GATTATGATG ATGATGATGA TGGCAGCATG 1080

GCCTCCTTGG AGAATGAAGG AAGAAAGAAA GATGTGGATG AAGAGAGCAC CTTCTCAGAT 1140

ACCAGCTCTT TTTTTAACTT CTGCAAGAAA AATAAAGAAA AACTGACCCC ATTGGAAAGG 1200

TGGAAGATCA AAAGGATTCA GTTTGGATGG AACAAAAAGA ATTCAGAAGC CCAAGAGGGC 1260

AAGAAGCCAG AAGGTGAAAG CAAAGAAGGG GAGGGTGAAG AAAAAAGTAA GCTGGATGTT 1320

GATCTTACAG CCTATCAGAA CTGGAGGTTG AAACGCCAGA AGAAACTGGG CAATAATAGC 1380

AAGGACGAGT TTGCAGAACT AGTCAAGGGT GAAGACGCTG CTTCTAGCAG AAGGAAGCAA 1440

AGACGAGCAG AGCTTCTGGA ACGTTCCAAG CAGACGTTGG AGGAAAGTCA GTCACTGTGT 1500

GGATGGGAGA CTGAGAGTGC TATGAGTGGA AGCATCCCAC TATCTACCTT CTTGCCCAAT 1560

ATGTCTGCTA GGAGTGCCAC CGATGACACA GCTTCCATGC TGAGTATGCA AAGCAATAGA 1620

TCTTCACTGT CCCAAGCTCG GAGTAATTCT GGTTTGCCTC AAACTCCTTT GCCCAACCTC 1680

CTGGTAGGGC CTGATGATAC AGTTTCATTA GCCAGCATTC AGAATTGGAT AGCCAATGTA 1740

GTTACTGAAA CAATAGCCCA AAAACAGAAT GAGATGATGC TTCAAGCTCA GCCTCCTTCT 1800

GCCATAAGTG ACAGCAGTAG GACAAGCAAT CTTTTAAGAG GCACTGAAGA TGACAAGATC 1860

TCTTTGCTTA GCATGCAAAG TGACATGTCC TATGGTAGCT CCTTACTGCG ACAGACAGAC 1920

GCAAGAAGCA CAGATACTCG GTCTGTCATG TCCTGTGGCA GTACATCAGG CCTTCAGTCG 1980

GGAGCCTTTG GTGCAAGGGA TAAAGTTACA GGCACAAGCA AGCCAATGTA TAGCTTGTTT 2040

GTTGATGATG TAGACCTTAA AAAGTTAAAC CGCAAAGAGA AGGAAATGAA AACTGAAATG 2100

CGAGGGAAAA TGTTTGAGTA CACAAAGGAA AAGATTGCAT CCGACAACAA ACGCAGCACC 2160

TTATTCAAGA AGAAAAAAGC CAAAGATGAT GATGAAGACA GTGATTTCAA AGAATTCACT 2220

TCTGGACATG CTCAGTATTT AAACAAATCT GATACAGTTT CCAATATCTC TGGCTGCTGT 2280

GCAAATTTAG GCACAGTTAG CACAGAATCT TTCAGTGACA TCGACAAGTG GCTTAGCAGT 2340

GTGAAATCTC CAGCTAGGGC TCCAAAGCTT GATGGCAGTG AAAAAACAAA TCTTGGATAC 2400

ACTGACTCAT CTTACCAAAA GGGCTTTGAA TCTAAAACAT CTGATTTTAG GCACTCAAGA 2460

TCTACAGCAG GGGAATTAAG GAGTACCTCT TCATCAGAAG TAAGAGAAAA TGGCTTCAGC 2520

ACTTCATCAA GACAGGTTCT TACTGCAACG GAAGCAGAAA GAAAACCTTC ACACAGACCC 2580

AAGGCTGCAG AAATGACAGG AACCAGAGAA GAAAGCACTG AGCCTTACTT CTTCAGTAGG 2640

ACGCCAGATT CAACCAGCAA TGGTGAGTCA GAGTCTCCCA AGCCAACAAA CAGCAGATTA 2700

AGATCACCTC ATCACCCAGC TGAAAAAGAA GCCTCAGAAG ACCAAGCTGT ATCTGATCTG 2760

GGGCCCAAGA GAAAATTTGC CTCCAGTTTT AGGGAAAGAA GAGGAAATGA TGAGGCTACG 2820

ACCCTCAGTA ATAATGATGA GGATGAGGAT GGCACAGCAC ACAGGAGCTA CAGGCGCAGA 2880

CCAAGAGCCA ACAACGAGAC TGAGGGAATG GATGATGATA AGCTAATTGC AGCATGGAGG 2940

AGTGGCAAGG AAGAAATGAG AGCAAAACTC CAAAGATTAA GAAAGGAA 2988

Domain Profile

S: 16    taldrreLsklgitvvinaslsvikvqviPeylikkgityknipvdDsdvtdllqyfdea  75

         +a+++  L+++gi++v+n+++++    ++ e++  ++i+y++i++dD ++ d++++f++a

Q: 7     VAVNKARLKRMGISHVLNTAHGTGV-YTGTEFYAAMDIQYLGIEADDFPNVDISKHFRKA  65

         689******************8765.7999******************************

S: 76    aefidea.kekggkvlvHCaaGvsRSatlvlaYLmkveglslsdAieavkrkrpsiepne  134

         aef+dea  + +gk+lv + +G+sRSatl+ aYLm++++ ++ +A+++++++r  i+pne

Q: 66    AEFMDEAlLTYKGKILVNSVMGISRSATLIAAYLMIFHHKTIMEALMTIRKRR-PISPNE  124

         *******8899******************************************.699***

S: 135   gfleQLlelekkl  147

         gfl+QL+ l++ l

Q: 125   GFLKQLRDLNESL  137

         *******998765

Domain Sequence
(FASTA)

VAVNKARLKR MGISHVLNTA HGTGVYTGTE FYAAMDIQYL GIEADDFPNV DISKHFRKAA 60

EFMDEALLTY KGKILVNSVM GISRSATLIA AYLMIFHHKT IMEALMTIRK RRPISPNEGF 120

LKQLRDLNES L 131

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0008138	; F:protein tyrosine/serine/threonine phosphatase activity
GO:0006470	; P:protein dephosphorylation

KEGG

InterPros

IPR020417	; Atypical_DUSP.
IPR020405	; Atypical_DUSP_famA.
IPR000340	; Dual-sp_phosphatase_cat-dom.
IPR020422	; Dual-sp_phosphatase_subgr_cat.
IPR024950	; DUSP.
IPR000387	; Tyr/Dual-specificity_Pase.

Pfam

PF00782

; DSPc; 1.

SMARTs

SM00195

; DSPc; 1.

Prosites

PS50056	; TYR_PHOSPHATASE_2; 1.
PS50054	; TYR_PHOSPHATASE_DUAL; 1.

Prints

PR01908	; ADSPHPHTASE.
PR01909	; ADSPHPHTASEA.

Created Date

20-Feb-2013