EKS-LAC-00274

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-LAC-00274

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/PLK	408.8	1.1E-122	15	267	253

Status

Unreviewed

Ensembl Protein

ENSLACP00000003940

UniProt Accession

H3A2R9;

Protein Name

Protein Synonyms/Alias

Gene Name

PLK3

Gene Synonyms/Alias

PLK3;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSLACG00000003507	ENSLACP00000003940	ENSLACT00000003976

Organism

Latimeria chalumnae

Functional Description

Protein Length

617

Protein Sequence
(FASTA)

ESGRIISDPN TGKHYCKGRL MGKGGFARCY EMTDTSNNKT YAVKVIPHSR VAKPHQKEKI 60

INEIELHKLL HHKHIVKFSH HFEDSENIYI FLEHCSRKSL AHIWKARHTL TEPEVRYYLK 120

QIISGLKYLH NRGILHRDLK LGNFFINENM ELKVGDFGLA AKLEPVDTRK KTICGTPNYL 180

APEVLHRQGH GPESDIWSLG CVMYTLLCGT PPFETSNLKE TYRCIKQVKY SLPACLSGVA 240

RRLIGSILKG NPQERLTLDE ILNHEFFTKG YTPDKLPPSS CVVMPELNPP NPAKNILTRV 300

AKSLFGKRKT KTKSPPTEER DDIARLASDL AKITVTRQMS YKTAEGNEVT LPTGQTANSS 360

PVRAEVEDGS RKSIHRSLRC SSQSASAGSE MFEDYTTASA VTDSAIRILK DTLSSMPAAD 420

RMPACVSRPC PFIWVTKWVD YSNKHGFGYQ LSNGSIGVLF NDGTHLGLSA DQRLVHYYLT 480

NTKHFSFPAT AVPEQLQAQM SLLQYLAKFM EQNLMQGGDL PSTEVQGQSP LFLLQWVKND 540

HALLMLFSNG TLQINFYNDH TKIILCKVEH SYHLTYINKE RTACTYKLSM LMEQGCSQSL 600

LHRMRNTLKL LQQKPEA 617

Nucleotide Sequence
(FASTA)

GAATCGGGGC GGATTATCAG CGACCCCAAC ACGGGCAAGC ACTACTGCAA AGGCAGGCTG 60

ATGGGCAAGG GCGGGTTTGC ACGCTGCTAT GAAATGACGG ACACCTCCAA TAACAAGACT 120

TATGCAGTCA AGGTGATTCC ACACAGCCGA GTGGCAAAAC CTCATCAGAA GGAGAAGATT 180

ATCAATGAAA TCGAGTTACA CAAACTTCTG CATCACAAGC ACATAGTGAA ATTTTCCCAT 240

CATTTTGAGG ACAGTGAAAA CATCTACATT TTTCTGGAAC ATTGTAGTAG AAAGTCTCTG 300

GCACATATCT GGAAAGCCAG GCACACGCTA ACGGAGCCTG AAGTGCGATA TTACTTGAAA 360

CAGATCATAT CGGGGCTGAA ATATCTCCAT AACAGGGGCA TCCTGCACAG AGACCTCAAG 420

CTGGGTAACT TTTTCATTAA TGAGAACATG GAGCTGAAGG TTGGAGATTT TGGATTGGCT 480

GCTAAACTCG AGCCTGTAGA TACGAGGAAG AAGACTATCT GTGGGACCCC AAACTACTTG 540

GCCCCTGAAG TGTTACACAG ACAGGGTCAC GGCCCTGAGT CAGACATCTG GTCTCTTGGC 600

TGCGTTATGT ACACCCTGCT GTGTGGGACG CCACCCTTTG AGACCTCAAA CCTGAAGGAG 660

ACTTACCGCT GTATCAAGCA GGTGAAATAC TCCTTGCCCG CCTGCCTCTC GGGTGTGGCC 720

AGGCGACTGA TCGGGTCCAT CCTGAAGGGA AATCCTCAAG AGCGCCTCAC CCTGGACGAA 780

ATCCTCAACC ATGAGTTCTT CACTAAAGGT TATACCCCCG ACAAGCTACC TCCCAGCAGT 840

TGTGTGGTGA TGCCAGAACT GAACCCACCA AACCCGGCCA AGAATATCCT CACCCGAGTC 900

GCCAAGAGCC TCTTTGGTAA AAGGAAAACG AAAACTAAGA GCCCCCCTAC AGAGGAGAGA 960

GATGACATCG CAAGACTAGC CAGCGACTTG GCAAAAATCA CCGTCACCCG ACAAATGAGC 1020

TACAAGACAG CAGAGGGGAA TGAGGTTACA CTACCGACAG GCCAGACTGC CAACTCCAGT 1080

CCTGTAAGAG CAGAAGTCGA AGATGGGTCC CGAAAATCCA TCCACCGATC CCTCCGCTGC 1140

AGCTCCCAGT CTGCTTCTGC TGGCAGTGAG ATGTTTGAAG ACTATACAAC AGCCTCTGCG 1200

GTCACTGACT CTGCGATCCG GATCCTGAAG GACACACTCT CCTCCATGCC TGCAGCAGAC 1260

AGAATGCCTG CCTGCGTGTC GAGACCCTGT CCCTTCATCT GGGTAACCAA ATGGGTGGAT 1320

TATTCCAACA AGCATGGCTT CGGGTACCAG CTGTCCAATG GGAGCATTGG CGTCCTCTTC 1380

AACGACGGCA CACACCTGGG CCTCTCAGCA GATCAAAGAT TGGTGCATTA CTACCTGACC 1440

AACACTAAGC ATTTCAGCTT CCCTGCCACG GCCGTCCCCG AACAGCTCCA GGCCCAGATG 1500

AGTCTCCTGC AGTACCTGGC CAAGTTTATG GAGCAGAATC TCATGCAGGG CGGAGATTTA 1560

CCCAGTACAG AAGTTCAAGG CCAGTCGCCC CTCTTCCTCT TACAGTGGGT GAAGAATGAC 1620

CATGCTTTAC TGATGCTGTT TAGCAATGGA ACTCTACAGA TAAACTTCTA CAATGACCAC 1680

ACCAAGATAA TCCTGTGCAA AGTGGAGCAT TCCTATCACC TGACCTATAT CAACAAGGAG 1740

CGCACGGCCT GTACCTACAA GCTGAGCATG CTGATGGAAC AGGGCTGCTC CCAGTCTCTC 1800

CTGCACCGCA TGCGCAACAC CCTGAAGCTG CTACAGCAGA AGCCAGAGGC CTAG 1854

Domain Profile

S: 1     yergkllGkGgfakcyelkdletkevfavkvvpksllakekqrekvekeieihrslkhkn  60

         y++g+l+GkGgfa+cye++d+++++++avkv+p+s++ak++q+ek+ +eie+h+ l+hk+

Q: 15    YCKGRLMGKGGFARCYEMTDTSNNKTYAVKVIPHSRVAKPHQKEKIINEIELHKLLHHKH  74

         89**********************************************************

S: 61    ivklyeffedkenvylvlelcsrrslaellkrrkaltepevryylrqivsglkylhekri  120

         ivk++++fed+en+y++le csr+sla+++k+r++ltepevryyl+qi+sglkylh++ i

Q: 75    IVKFSHHFEDSENIYIFLEHCSRKSLAHIWKARHTLTEPEVRYYLKQIISGLKYLHNRGI  134

         ************************************************************

S: 121   lhrdlklgnlflneelevkigdfGlatrlekeeerkktlcGtPnyiaPevlskkghslev  180

         lhrdlklgn+f+ne++e+k+gdfGla++le+ + rkkt+cGtPny+aPevl+++gh+ e+

Q: 135   LHRDLKLGNFFINENMELKVGDFGLAAKLEPVDTRKKTICGTPNYLAPEVLHRQGHGPES  194

         ************************************************************

S: 181   diWslGcilytllvGkPPfetkelketyekikkaeyslPsslskeaksliakllkkePee  240

         diWslGc++ytll+G+PPfet++lkety++ik+ +yslP+ ls  a++li ++lk +P+e

Q: 195   DIWSLGCVMYTLLCGTPPFETSNLKETYRCIKQVKYSLPACLSGVARRLIGSILKGNPQE  254

         ************************************************************

S: 241   rpsleevlkdefl  253

         r++l+e+l++ef+

Q: 255   RLTLDEILNHEFF  267

         ************8

Domain Sequence
(FASTA)

YCKGRLMGKG GFARCYEMTD TSNNKTYAVK VIPHSRVAKP HQKEKIINEI ELHKLLHHKH 60

IVKFSHHFED SENIYIFLEH CSRKSLAHIW KARHTLTEPE VRYYLKQIIS GLKYLHNRGI 120

LHRDLKLGNF FINENMELKV GDFGLAAKLE PVDTRKKTIC GTPNYLAPEV LHRQGHGPES 180

DIWSLGCVMY TLLCGTPPFE TSNLKETYRC IKQVKYSLPA CLSGVARRLI GSILKGNPQE 240

RLTLDEILNH EFF 253

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000959	; POLO_box_duplicated_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.
IPR020658	; Ser/Thr_kinase_Plk3.

Pfam

PF00069	; Pkinase; 1.
PF00659	; POLO_box; 2.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS50078	; POLO_BOX; 2.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013