EPS-LAC-00034

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-LAC-00034

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPM/PP2C	200.0	6.7E-59	82	335	254

Status

Unreviewed

Ensembl Protein

ENSLACP00000004544

UniProt Accession

H3A4H3;

Protein Name

Protein Synonyms/Alias

Gene Name

PPM1E

Gene Synonyms/Alias

PPM1E;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSLACG00000004046	ENSLACP00000004544	ENSLACT00000004583

Organism

Latimeria chalumnae

Functional Description

Protein Length

611

Protein Sequence
(FASTA)

FFSSHLPFQF CAALARATAD EILQSDLSTQ FISKHVDGTE GIAQIEALKL ARLIFTKLRE 60

ICYSWLKDLP LRKKSHPYYE TSIHAVKNMR RKMEDKHVCI PDINILFNLE DQEEQAYFAV 120

FDGHGGVDAA IYASIHLHVN MVRQEMFRHD PEEALRRAFH VTDERFVQKA ARESLRCGTT 180

GVVTLIRGDR LHVAWLGDSQ VMLVRRGAAV ELMKPHKPDR EDEKQRIEAL GGCVVWFGAW 240

RVNGSLSVSR AIGDAEHKPY ICGDADTFYT ALDGSEDYLI LACDGFYDTV SPDEAVKVVA 300

DHLRENDGDI TMVAHKLVAS ARDAGSSDNI TVVVVFLRDV NAVENVSVDS SWMQNSFERG 360

QDDNGDDKEN HGDCKGTWPQ HQCSAPADLC YEDRMDSFTD RTSLSLGPNI SIFQDKDYLD 420

LKESEGLKAR SAKLVPSIIQ IFGQPIPKKI NLVKNVIRNK ETSTRISVYR HIDTFQCQTS 480

TLVDIGYIGD PFYKMESLPL LRIWFEDEHW KSLKKGNSGF SQFHLRYKKR WSRRGTRIKP 540

KHRALPFIQE PCHKPGAILS LLIRSSNKNR KLVKHAVPWR KTSHKGHHEK MWMLSRSSTI 600

PYPDLDGCCN I 611

Nucleotide Sequence
(FASTA)

TTTTTTTCCA GCCATTTACC ATTCCAGTTT TGTGCTGCTT TGGCAAGAGC AACAGCAGAT 60

GAGATCCTTC AGAGTGATCT TTCAACACAA TTCATATCAA AGCATGTGGA TGGTACAGAG 120

GGGATTGCAC AGATTGAAGC TTTGAAGCTT GCCCGCCTGA TATTCACTAA ACTGCGAGAG 180

ATTTGCTACA GCTGGCTAAA AGATTTGCCA CTTAGGAAAA AATCCCATCC CTACTATGAA 240

ACATCCATCC ATGCTGTTAA AAACATGCGC AGGAAGATGG AGGACAAACA TGTCTGCATT 300

CCTGATATTA ATATTCTGTT CAACCTAGAG GATCAAGAGG AACAAGCTTA CTTTGCAGTG 360

TTTGATGGCC ATGGTGGAGT TGATGCAGCT ATCTATGCTT CCATCCACCT CCACGTCAAC 420

ATGGTGCGTC AAGAGATGTT CCGGCATGAC CCGGAAGAGG CACTACGCAG AGCATTTCAT 480

GTGACAGATG AGCGGTTTGT CCAGAAAGCA GCTAGAGAGA GCTTACGATG TGGAACCACT 540

GGTGTAGTCA CGTTAATCCG AGGAGACAGG TTACATGTGG CATGGCTGGG CGACTCCCAG 600

GTTATGTTAG TGAGAAGAGG GGCAGCAGTG GAACTAATGA AGCCTCACAA ACCAGACAGA 660

GAGGATGAGA AGCAACGTAT TGAAGCACTT GGAGGCTGTG TGGTCTGGTT TGGTGCATGG 720

AGGGTCAACG GAAGCCTTTC AGTTTCTAGA GCCATTGGAG ATGCTGAGCA TAAGCCATAT 780

ATTTGTGGAG ATGCAGACAC TTTCTACACT GCACTGGATG GAAGTGAAGA CTACCTCATC 840

CTAGCTTGCG ATGGCTTTTA TGATACAGTG AGTCCAGATG AGGCAGTGAA GGTTGTAGCA 900

GATCACCTGA GAGAGAATGA TGGCGATATA ACCATGGTTG CCCATAAATT GGTGGCATCA 960

GCTCGGGATG CAGGTTCTAG TGACAATATC ACTGTCGTGG TAGTATTCCT CAGGGACGTG 1020

AATGCTGTGG AAAATGTTAG TGTTGACTCT AGTTGGATGC AGAACTCTTT TGAAAGAGGA 1080

CAAGACGACA ATGGGGATGA TAAAGAAAAT CATGGGGACT GCAAAGGAAC TTGGCCACAG 1140

CATCAGTGCT CTGCACCTGC TGATTTATGC TATGAAGATC GAATGGATTC TTTTACTGAC 1200

AGAACTAGTT TAAGTTTAGG CCCAAACATT AGCATTTTCC AAGACAAAGA TTATCTGGAT 1260

CTAAAAGAGT CAGAAGGATT GAAAGCTCGG AGTGCCAAAC TTGTACCATC AATCATACAA 1320

ATATTTGGTC AACCTATACC AAAGAAAATA AATTTGGTCA AAAATGTAAT AAGAAACAAG 1380

GAAACCTCTA CCAGAATATC AGTATACAGA CACATAGACA CTTTTCAGTG TCAAACTTCA 1440

ACCCTAGTAG ACATAGGTTA TATTGGGGAC CCATTCTACA AAATGGAGAG TTTGCCTCTC 1500

TTGAGAATTT GGTTTGAAGA TGAACACTGG AAAAGTCTAA AGAAAGGCAA TTCTGGGTTC 1560

TCTCAGTTTC ACCTCCGTTA TAAAAAGAGG TGGAGCAGAC GAGGAACAAG GATAAAACCA 1620

AAGCACCGTG CACTGCCTTT TATCCAAGAG CCTTGCCACA AACCAGGAGC CATCTTATCA 1680

TTACTTATCC GAAGCAGTAA CAAAAACAGG AAGCTAGTAA AACATGCAGT ACCATGGAGG 1740

AAAACCAGTC ACAAGGGTCA TCATGAAAAA ATGTGGATGC TAAGTCGGAG TAGCACTATA 1800

CCTTATCCAG ATCTAGATGG ATGCTGTAAT ATTTAA 1836

Domain Profile

S: 4     gvvsvngrrnemedavtsspnflkspekkdr..laffgvyDGhggsevakfcseklheil  61

         ++ +v+++r++med++   p++    + +d+   a+f+v+DGhgg ++a ++s +lh  +

Q: 82    SIHAVKNMRRKMEDKHVCIPDINILFNLEDQeeQAYFAVFDGHGGVDAAIYASIHLHVNM  141

         56789*************9987544433333338***********************988

S: 62    aeelesseseerkvkkalakaFlstdeelkvleeksldidksGstavvalikdsklyvan  121

          ++       + + ++al++aF  tde++  ++++  ++ ++G+t vv li+++ l+va

Q: 142   VRQEM----FRHDPEEALRRAFHVTDERF--VQKAARESLRCGTTGVVTLIRGDRLHVAW  195

         88855....6889999*************..7777788888*******************

S: 122   vGdSravLcrngkavelssdHkpsredEleRieeaggsvilkdga.RvlGvLavsRalGd  180

         +GdS+++L r g avel + Hkp+redE++Rie+ gg v+ + ga Rv+G+L vsRa+Gd

Q: 196   LGDSQVMLVRRGAAVELMKPHKPDREDEKQRIEALGGCVV-WFGAwRVNGSLSVSRAIGD  254

         *************************************999.55899**************

S: 181   lylkpyvtpePevtshrltsedefliLasDGlwdvvsneeavslvrdvle.kkeaeqeaa  239

          + kpy+  + +++++ l+ ++++liLa+DG +d+vs+ eav++v d+l+ ++ + + +a

Q: 255   AEHKPYICGDADTFYTALDGSEDYLILACDGFYDTVSPDEAVKVVADHLReNDGDITMVA  314

         ************************************************996778999***

S: 240   kkLvklalargskdnvsaivv  260

         +kLv+ a++ gs+dn++++vv

Q: 315   HKLVASARDAGSSDNITVVVV  335

         ****************99987

Domain Sequence
(FASTA)

SIHAVKNMRR KMEDKHVCIP DINILFNLED QEEQAYFAVF DGHGGVDAAI YASIHLHVNM 60

VRQEMFRHDP EEALRRAFHV TDERFVQKAA RESLRCGTTG VVTLIRGDRL HVAWLGDSQV 120

MLVRRGAAVE LMKPHKPDRE DEKQRIEALG GCVVWFGAWR VNGSLSVSRA IGDAEHKPYI 180

CGDADTFYTA LDGSEDYLIL ACDGFYDTVS PDEAVKVVAD HLRENDGDIT MVAHKLVASA 240

RDAGSSDNIT VVVV 254

Keyword

Complete proteome; Hydrolase; Magnesium; Metal-binding; Protein phosphatase; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Schizosaccharomyces pombe"; ?>