EKS-LAC-00069

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-LAC-00069

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDK	351.2	4.5E-105	10	297	288

Status

Unreviewed

Ensembl Protein

ENSLACP00000004612

UniProt Accession

H3A4P1;

Protein Name

Protein Synonyms/Alias

Gene Name

CDK6

Gene Synonyms/Alias

CDK6;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSLACG00000004106	ENSLACP00000004612	ENSLACT00000004651

Organism

Latimeria chalumnae

Functional Description

Protein Length

322

Protein Sequence
(FASTA)

MDKDSLAQLY EPVAEIGEGA YGKVYKARDL KNGGRFVALK KVRVQTGEEG MPLSTIREVA 60

VLRQLESFEH PNVVRLFDVC TVSRTDRETK LTLVFEHVDQ DLTTYLEKAP EPGVPPETIK 120

DMMFQLLRGL DFLHSHRVVH RDLKPQNILV TSSGQIKLAD FGLARIYSFQ MALTSVVVTL 180

WYRAPEVLLQ SSYATPVDLW SVGCIFAEMF RRRPIFRGNS DVDQLGKILD VIGLPEDEDW 240

PCDVSLPRNA FTPRPPQPIE KFVPDIDELG KDLLLKFLTF NPTKRISSYK SLSHPYFCDL 300

EKCSENLDSH LSSRQLSTEE NT 322

Nucleotide Sequence
(FASTA)

ATGGATAAAG ACAGCCTCGC TCAGCTGTAC GAACCCGTGG CTGAGATTGG GGAAGGAGCC 60

TATGGGAAGG TGTACAAGGC CCGGGATCTG AAGAATGGGG GCCGCTTCGT GGCGCTGAAG 120

AAGGTGCGGG TGCAGACTGG GGAGGAGGGG ATGCCGCTCT CCACCATCCG CGAGGTGGCA 180

GTGCTGAGGC AGCTGGAGTC CTTCGAGCAC CCCAACGTGG TCAGGTTATT TGATGTGTGT 240

ACGGTGTCTC GAACAGATCG GGAAACGAAA CTGACACTGG TCTTTGAGCA CGTGGATCAA 300

GATTTGACCA CTTATTTGGA GAAAGCTCCC GAGCCTGGTG TGCCCCCTGA AACTATAAAG 360

GATATGATGT TTCAGCTTCT TCGAGGTCTG GATTTCCTTC ATTCACACAG AGTGGTGCAT 420

CGGGACCTGA AGCCCCAGAA TATCCTCGTG ACCAGCAGTG GTCAGATCAA GCTCGCTGAC 480

TTTGGTCTAG CACGCATCTA CAGTTTTCAG ATGGCGCTTA CGTCAGTGGT TGTCACTTTG 540

TGGTATCGGG CACCAGAAGT CTTGCTTCAG TCTAGTTATG CAACACCAGT TGACCTCTGG 600

AGTGTTGGCT GTATATTTGC CGAAATGTTC CGACGAAGGC CAATTTTTCG TGGAAATTCA 660

GATGTTGATC AGCTGGGAAA AATCCTTGAT GTAATTGGTC TCCCTGAAGA TGAAGACTGG 720

CCCTGTGATG TGTCTCTTCC AAGGAATGCT TTTACCCCAA GACCTCCACA ACCCATTGAA 780

AAATTTGTAC CAGATATCGA TGAATTAGGA AAAGATTTAC TGCTTAAATT TTTGACCTTC 840

AACCCAACAA AAAGAATATC TTCATATAAA TCTCTTTCTC ATCCATACTT CTGTGACCTT 900

GAAAAATGCA GTGAGAACCT TGACTCTCAT TTGTCTTCAA GACAGCTTTC TACTGAGGAG 960

AATACA 966

Domain Profile

S: 1     yeklekigeGtygkvykakd.ketgevvAlKkirlekekegvpitalrEisllkel...k  56

         ye +++igeG+ygkvyka+d k+ g++vAlKk+r+++ +eg+p +++rE+++l++l   +

Q: 10    YEPVAEIGEGAYGKVYKARDlKNGGRFVALKKVRVQTGEEGMPLSTIREVAVLRQLesfE  69

         88899***************888999*****************************99889

S: 57    hknivkLlevva....kdkkklyLvfefleqdLkkllkkkkkkklsleevkslllqlleg  112

         h+n+v+L +v++     +++kl+Lvfe+++qdL+++l+k ++ ++++e++k +++qll+g

Q: 70    HPNVVRLFDVCTvsrtDRETKLTLVFEHVDQDLTTYLEKAPEPGVPPETIKDMMFQLLRG  129

         ************99855569****************************************

S: 113   laylHsnkilHRDlKpqNlLiskegklklaDfGlarafssplktytkevvTlwYraPelL  172

         l++lHs++++HRDlKpqN+L++++g++klaDfGlar +s ++  +t++vvTlwYraPe+L

Q: 130   LDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQMA-LTSVVVTLWYRAPEVL  188

         *****************************************99.****************

S: 173   lgakeYstavDiWsvgcilaelltrkplfqgkseidqlerifkllgtpsekvwpevsklp  232

         l++ +Y t vD+Wsvgci+ae+++r+p+f+g+s++dql +i++++g p++++wp   +lp

Q: 189   LQS-SYATPVDLWSVGCIFAEMFRRRPIFRGNSDVDQLGKILDVIGLPEDEDWPCDVSLP  247

         *88.5*******************************************************

S: 233   eykksfpkkkkkklkekvkklkekaldllekllaldpkkRisakealqhkyf  284

         +   +f++++++ +++ v++++e + dll k+l+++p+kRis+ + l+h+yf

Q: 248   RN--AFTPRPPQPIEKFVPDIDELGKDLLLKFLTFNPTKRISSYKSLSHPYF  297

         95..59999******************************************9

Domain Sequence
(FASTA)

YEPVAEIGEG AYGKVYKARD LKNGGRFVAL KKVRVQTGEE GMPLSTIREV AVLRQLESFE 60

HPNVVRLFDV CTVSRTDRET KLTLVFEHVD QDLTTYLEKA PEPGVPPETI KDMMFQLLRG 120

LDFLHSHRVV HRDLKPQNIL VTSSGQIKLA DFGLARIYSF QMALTSVVVT LWYRAPEVLL 180

QSSYATPVDL WSVGCIFAEM FRRRPIFRGN SDVDQLGKIL DVIGLPEDED WPCDVSLPRN 240

AFTPRPPQPI EKFVPDIDEL GKDLLLKFLT FNPTKRISSY KSLSHPYF 288

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Rattus norvegicus"; ?>Sorex araneus"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>