EKS-LAC-00215

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-LAC-00215

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/RCK	433.0	5.6E-130	11	292	282

Status

Unreviewed

Ensembl Protein

ENSLACP00000004715

UniProt Accession

H3A4Z4;

Protein Name

Protein Synonyms/Alias

Gene Name

MOK

Gene Synonyms/Alias

MOK;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSLACG00000004194	ENSLACP00000004715	ENSLACT00000004754

Organism

Latimeria chalumnae

Functional Description

Protein Length

425

Protein Sequence
(FASTA)

MKSCFLRMNK YRIIGQIGEG TFSEVMKTQS LRDGKYFACK KMKQRFYSTG QVDNLREIQA 60

LRRLSPHPNI LQLHEVIFDK KTGSLALICE LMDMNIYELI RGKRQLLPES KIKNYMYQLC 120

KSLDHMHKNG IFHRDVKPEN ILIKQDILKL ADFGSCRSVY SKQPYTEYIS TRWYRAPECL 180

LTDGYYSYKM DIWSLGCVFF EITSLNPLFP GVNELDQISI IHDILGTPDK RTLNKFKQSS 240

AMSFNFPFKK GSGLSRLIPY ATSDSLSLMY AMIEYDPGER ITAKEALKHP YFGELRAAEK 300

QSATLRHMNH LRENTGNSSS RDNLIRIAKL GRKQQHLKHI QEPLIRRQVP AFPVELPKLH 360

VSGASTSYPT NSFQSIFPTI PHRGTLPILQ TVKCTGKGGK PGSQQLKLPM KQYHLPSIEK 420

KDREY 425

Nucleotide Sequence
(FASTA)

ATGAAATCAT GCTTTTTGAG GATGAACAAA TACAGAATAA TTGGTCAAAT TGGAGAGGGA 60

ACATTCTCTG AAGTTATGAA GACACAGAGC CTTAGGGATG GGAAATATTT TGCATGTAAA 120

AAGATGAAAC AACGCTTTTA CAGTACTGGA CAAGTAGACA ACCTGCGAGA GATCCAAGCT 180

TTAAGAAGAC TGAGTCCACA TCCAAATATT CTTCAGTTAC ATGAAGTAAT ATTTGATAAA 240

AAGACTGGCT CCCTTGCTTT AATATGTGAA CTTATGGATA TGAATATTTA CGAGCTTATA 300

CGAGGTAAAA GGCAGCTGTT ACCTGAAAGT AAAATAAAGA ATTATATGTA CCAGCTATGT 360

AAGTCCCTGG ATCACATGCA CAAAAATGGA ATCTTTCATC GAGATGTAAA ACCAGAAAAC 420

ATCTTGATAA AGCAAGATAT ACTGAAGCTG GCAGACTTTG GCTCCTGCAG GAGCGTGTAC 480

TCCAAGCAGC CATATACAGA ATATATCTCT ACTCGTTGGT ATCGAGCTCC CGAGTGCCTT 540

CTAACAGATG GGTATTACAG TTATAAGATG GATATCTGGA GTCTTGGCTG TGTTTTCTTT 600

GAAATAACAA GCCTAAATCC CCTCTTTCCG GGAGTCAATG AATTGGACCA GATTTCCATA 660

ATCCATGATA TTCTAGGCAC TCCTGATAAA AGAACTCTTA ACAAGTTTAA ACAATCAAGT 720

GCCATGAGTT TCAACTTTCC TTTCAAAAAA GGCTCAGGAT TATCTCGCCT CATACCTTAT 780

GCCACTTCTG ATAGCCTCTC CCTCATGTAT GCGATGATAG AATATGACCC TGGTGAGAGA 840

ATCACTGCTA AAGAAGCTTT GAAGCACCCT TATTTTGGAG AGCTCAGGGC AGCAGAGAAG 900

CAATCTGCTA CATTACGTCA CATGAATCAT CTACGTGAAA ATACTGGAAA TTCAAGCTCA 960

AGGGATAATT TAATAAGAAT TGCAAAACTA GGTCGCAAAC AGCAACACCT GAAGCATATC 1020

CAGGAGCCTT TAATAAGACG CCAAGTTCCA GCTTTTCCAG TGGAACTGCC AAAGCTTCAT 1080

GTTTCTGGAG CATCCACTTC TTATCCTACT AACTCCTTCC AGTCAATCTT TCCCACAATA 1140

CCACACAGGG GAACACTTCC CATACTACAA ACAGTGAAGT GTACTGGTAA AGGTGGTAAG 1200

CCTGGAAGCC AACAGCTGAA ACTTCCTATG AAGCAATACC ACTTACCTTC TATTGAAAAA 1260

AAGGATAGAG AATACTAA 1278

Domain Profile

S: 1     yklikklGdGtfgevllakslktgelvaikkmkrkfesleevtnlrevkslkklnahdni  60

         y++i ++G+Gtf+ev++++sl++g+++a+kkmk++f+s  +v nlre+++l++l++h+ni

Q: 11    YRIIGQIGEGTFSEVMKTQSLRDGKYFACKKMKQRFYSTGQVDNLREIQALRRLSPHPNI  70

         899*********************************************************

S: 61    iklkeviidrendslylvlelmeenlyqlikdrrkllsesklksilyqilkglafihkhg  120

         ++l+evi+d++ +sl+l++elm++n+y+li+++r+ll+esk+k+++yq++k+l+++hk+g

Q: 71    LQLHEVIFDKKTGSLALICELMDMNIYELIRGKRQLLPESKIKNYMYQLCKSLDHMHKNG  130

         ************************************************************

S: 121   ffhrdlkPenilikgselvkladfGlarevrsknPytdyvstrwyraPevllrsgvyssp  180

         +fhrd+kPenilik ++++kladfG++r+v+sk+Pyt+y+strwyraPe+ll++g+ys++

Q: 131   IFHRDVKPENILIK-QDILKLADFGSCRSVYSKQPYTEYISTRWYRAPECLLTDGYYSYK  189

         **************.*********************************************

S: 181   ldlwavGcvlaevavlrplfPGaseidqifkilevlGtPkkkewdeayklasalnlkfpq  240

         +d+w++Gcv+ e+++l+plfPG++e+dqi+ i+++lGtP+k+++++ +k++sa++++fp+

Q: 190   MDIWSLGCVFFEITSLNPLFPGVNELDQISIIHDILGTPDKRTLNK-FKQSSAMSFNFPF  248

         *********************************************9.*************

S: 241   vegsslktlvsnaskealellkdllaydPderataqqalkypyf  284

         ++gs+l++l++ a +++l+l+ ++++ydP er+ta++alk+pyf

Q: 249   KKGSGLSRLIPYATSDSLSLMYAMIEYDPGERITAKEALKHPYF  292

         *******************************************9

Domain Sequence
(FASTA)

YRIIGQIGEG TFSEVMKTQS LRDGKYFACK KMKQRFYSTG QVDNLREIQA LRRLSPHPNI 60

LQLHEVIFDK KTGSLALICE LMDMNIYELI RGKRQLLPES KIKNYMYQLC KSLDHMHKNG 120

IFHRDVKPEN ILIKQDILKL ADFGSCRSVY SKQPYTEYIS TRWYRAPECL LTDGYYSYKM 180

DIWSLGCVFF EITSLNPLFP GVNELDQISI IHDILGTPDK RTLNKFKQSS AMSFNFPFKK 240

GSGLSRLIPY ATSDSLSLMY AMIEYDPGER ITAKEALKHP YF 282

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona savignyi"; ?>Dasypus novemcinctus"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013