EPS-LAC-00036

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-LAC-00036

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPM/PP2C	180.2	7.2E-53	644	890	247

Status

Unreviewed

Ensembl Protein

ENSLACP00000005064

UniProt Accession

H3A5Z3;

Protein Name

Protein Synonyms/Alias

Gene Name

PHLPP2

Gene Synonyms/Alias

PHLPP2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSLACG00000004505	ENSLACP00000005064	ENSLACT00000005110

Organism

Latimeria chalumnae

Functional Description

Protein Length

1186

Protein Sequence
(FASTA)

KPCSGDQLDR ILLSGVFSVR KGKTQLHKWS ERLVILCGTC LIVSSVKECQ AGKMHVLQLV 60

GGKVEEVKRR QHCLAFSSAG PQLQTYFVSF DSPTECQRWL RQAAKVVSQR LSSVDLSCYS 120

LEEVPEPLFY SQDITQLNLR QNFLRLDGEG GLANLSRFSQ LKNLNLSQNR LGVFLESVCE 180

IVTLTELNLS CNGIQTLPPA IGNLLSLQNL ALDGNLLCSL PDELTNLKQL SSLGLSFNNF 240

ATIPEVCERL TTIDRLAMTG NQLETLPLDA LGRATHLKCI DLRLNSLSTV TLESLEVNKH 300

ITQLDLRDNQ LMELDLSSLG SLTQLHCERN RLRELSLSGF SLRALHAGSN RLTAVNIYPV 360

PTQLTSLDLS RNYLECVPDW VCEARKIEVL DFSWNHLIEL PARYVENTSL SIKGTVVVRS 420

SIQWWFMLLP EYVTYKLSDL ELLQKYIFSH VSVARKVDLP FNSQKYMPPE YIEDCIGLVW 480

VFFLLENIYK VMKMCVCVFH SSLTPFDSLK NFDLCGAPSI KLSKLEQLEE LNMSGNKLRT 540

VPTTISNCKR LHSLSAHSNN ISVFPEILNL PEIKFVDLSC NELTEIVIQE TLPPTLQELD 600

LTGNTNLVLE HRTLDIFSHI PTLKMDQKAS MMSSDLTGSP LLWNHGFAEM AGQKNKLCVS 660

VLAVDNFTDG VEALYGMFDG DKNEEVPRLL QCTMGDVLSE EVQQSSVDAV YMTNTFLVSH 720

RKLGMSGQKL GSSALLCYIR HDPSDSGSYF SVTQANVGTC QAVLCRDGQP LPLSRVFSLE 780

NCNEETQRVK LQKAIITEDN KVNGVTCCSR QLGCTYLHPW VLPTPHVHTV PLTPQDDLLV 840

LGNRALWEYL SYKEAIAAVQ NMPDPKAAAK KLCTLAQSYG CRDNVGAVVV YLSLGDDSCT 900

CEMPGAPLGS SGVDAPPVGV VKDALEPATP SLSSGIASEF SSEMSASEVS SEVGSTASDE 960

QTSAGLDGGL LGRPERRCSL HPLPNTSLFQ RQPSCATFSS NQSDNGLDSD DDQPVEGVMS 1020

NGSKVEVEVD IHCFKGKDPK PASPLSGQDI TLPCHNSEDD SPGLCFKIQR QNSINSGALL 1080

AVGRERTDLK KSPSTSSLYG KKLSNGSVVP LEESLNLIEV ANEAPKKKTG YFAAPAQLDP 1140

EDQFIVPPDL EEEVREQIKQ HQEQISESAA NRESRTVLTE VYDTAL 1186

Nucleotide Sequence
(FASTA)

AAGCCCTGTA GTGGGGATCA GTTGGATCGA ATCCTGCTGT CGGGGGTCTT CAGCGTTCGG 60

AAGGGGAAGA CGCAGCTGCA CAAGTGGTCG GAACGGCTGG TGATTCTCTG CGGTACCTGC 120

CTGATCGTGT CGTCTGTGAA GGAATGTCAG GCGGGGAAGA TGCACGTCCT CCAGCTGGTG 180

GGGGGGAAGG TTGAAGAGGT GAAGCGGCGC CAGCACTGCC TAGCATTCAG CTCAGCGGGA 240

CCTCAGTTGC AGACCTATTT TGTCAGCTTT GATTCACCTA CCGAGTGTCA GCGCTGGCTT 300

CGGCAGGCCG CCAAGGTGGT TTCTCAGCGG CTCAGCAGTG TGGATCTCTC ATGCTACAGC 360

CTGGAGGAGG TCCCCGAGCC CCTTTTTTAC AGCCAGGACA TTACACAGCT CAACCTACGA 420

CAGAACTTCC TGCGCCTGGA TGGTGAGGGC GGACTCGCTA ACCTCAGCAG GTTTTCGCAG 480

CTGAAGAATC TCAACCTGTC CCAAAACCGC CTGGGTGTGT TCCTGGAATC GGTGTGCGAG 540

ATTGTCACTC TAACCGAACT TAATCTGTCC TGTAATGGCA TCCAAACCCT GCCGCCAGCC 600

ATAGGGAACC TGCTGAGCCT GCAGAATCTG GCATTGGATG GGAATTTGCT ATGCTCCCTC 660

CCAGATGAGC TCACCAACTT GAAGCAGCTC AGCTCCCTTG GCCTCTCCTT CAATAACTTC 720

GCCACAATCC CAGAGGTCTG TGAGCGCTTG ACCACTATAG ACAGACTAGC TATGACAGGG 780

AACCAGCTGG AAACGTTGCC ATTGGACGCA CTCGGCAGGG CCACACATCT AAAATGCATC 840

GATCTCAGGC TGAACTCTCT GTCCACGGTG ACTCTGGAGA GCCTGGAGGT CAACAAGCAC 900

ATCACGCAGC TGGACCTGAG GGACAATCAG CTGATGGAGC TGGACCTGAG CTCCCTGGGC 960

AGCCTGACGC AGCTTCACTG TGAGAGGAAC CGGCTGAGGG AACTGAGTCT GAGCGGCTTC 1020

TCTCTCCGAG CACTGCATGC CGGATCCAAC CGACTGACAG CAGTGAATAT TTATCCGGTT 1080

CCCACTCAAC TCACCAGCCT GGACCTTTCC AGGAACTATT TAGAGTGTGT GCCAGATTGG 1140

GTGTGCGAAG CCAGGAAGAT CGAGGTCTTG GATTTTAGCT GGAACCACCT GATAGAGCTA 1200

CCAGCCAGGT ATGTAGAAAA TACCTCTCTT TCTATAAAAG GAACTGTAGT GGTTAGAAGC 1260

AGTATACAAT GGTGGTTTAT GTTGCTTCCA GAGTATGTAA CATACAAACT TTCTGATCTG 1320

GAATTACTGC AAAAATATAT TTTTAGTCAT GTGAGTGTTG CTAGAAAGGT GGACCTCCCC 1380

TTTAATAGCC AGAAGTACAT GCCTCCTGAA TATATAGAGG ATTGCATAGG TTTGGTGTGG 1440

GTTTTTTTTC TTTTAGAAAA TATATATAAA GTAATGAAAA TGTGTGTGTG TGTGTTTCAT 1500

TCGAGTTTGA CTCCTTTTGA TTCTCTAAAG AATTTTGATC TCTGCGGAGC TCCATCCATT 1560

AAGTTGAGCA AGTTGGAGCA ACTGGAGGAG TTGAACATGA GTGGAAACAA GCTGAGGACG 1620

GTCCCCACCA CCATCTCCAA CTGCAAGAGG TTGCACAGCC TTTCTGCTCA TTCCAACAAT 1680

ATCAGTGTCT TCCCGGAGAT CTTGAACTTA CCGGAAATCA AGTTTGTGGA CCTGAGTTGC 1740

AACGAGCTGA CGGAGATTGT GATCCAGGAG ACGCTGCCTC CGACTCTGCA GGAGCTCGAC 1800

CTGACCGGGA ACACAAACCT CGTTTTGGAG CACAGGACCC TCGATATCTT CAGTCACATC 1860

CCAACGTTGA AAATGGATCA GAAGGCATCG ATGATGTCAT CGGACTTAAC AGGAAGCCCC 1920

TTGCTCTGGA ATCATGGGTT TGCAGAAATG GCTGGCCAGA AAAACAAGCT TTGTGTCTCA 1980

GTGCTGGCTG TGGATAACTT CACTGACGGA GTGGAAGCTC TTTATGGCAT GTTTGATGGC 2040

GATAAAAATG AGGAGGTGCC GCGCCTGCTG CAGTGCACCA TGGGAGATGT CTTATCCGAA 2100

GAGGTTCAGC AGTCCAGCGT AGATGCAGTT TACATGACCA ACACATTCCT TGTTTCACAC 2160

AGAAAACTGG GGATGTCTGG CCAGAAGTTG GGTTCGTCGG CTCTACTGTG TTACATCCGC 2220

CATGACCCCA GTGACTCAGG GAGTTATTTC AGTGTGACGC AGGCGAACGT AGGGACATGC 2280

CAGGCTGTGC TGTGCCGAGA CGGACAGCCC CTCCCCCTCT CCCGGGTCTT TAGTTTGGAA 2340

AACTGCAATG AAGAGACTCA GAGGGTCAAA CTCCAAAAAG CCATAATAAC TGAGGACAAT 2400

AAAGTGAACG GTGTGACCTG CTGCAGTCGA CAGTTGGGCT GCACCTACCT CCACCCCTGG 2460

GTCCTGCCAA CACCTCACGT CCACACCGTC CCCCTCACCC CTCAAGATGA CCTCCTCGTC 2520

CTGGGGAACA GGGCACTCTG GGAGTACCTG TCTTACAAAG AGGCCATTGC TGCTGTACAG 2580

AACATGCCTG ACCCCAAAGC AGCTGCAAAG AAACTATGCA CACTGGCTCA GAGCTATGGT 2640

TGCCGGGACA ATGTGGGTGC AGTTGTGGTT TATTTGAGCC TCGGAGATGA CAGCTGCACG 2700

TGTGAGATGC CTGGAGCCCC TCTGGGTAGC TCAGGGGTTG ATGCCCCACC TGTTGGAGTC 2760

GTGAAGGATG CACTGGAGCC GGCAACCCCG TCCCTGAGCA GCGGGATTGC GTCAGAGTTC 2820

AGCAGCGAGA TGTCTGCCTC GGAGGTCAGC AGCGAGGTCG GCTCAACGGC TTCAGACGAA 2880

CAGACCTCAG CGGGGCTTGA CGGTGGACTG CTTGGACGCC CTGAACGGCG ATGCAGTCTC 2940

CACCCGCTGC CCAACACCAG CCTCTTCCAG CGGCAGCCAT CTTGTGCCAC ATTTTCCAGC 3000

AACCAGTCGG ACAACGGCTT GGACAGCGAC GACGACCAGC CAGTGGAAGG GGTTATGTCC 3060

AATGGCAGCA AAGTGGAGGT GGAAGTGGAC ATTCATTGCT TCAAGGGTAA AGACCCTAAA 3120

CCTGCGAGCC CTTTGTCAGG TCAGGACATA ACTCTACCTT GCCATAACTC TGAGGATGAC 3180

TCCCCAGGAC TCTGCTTCAA AATCCAACGT CAGAACAGCA TCAACAGCGG AGCCCTGCTG 3240

GCCGTGGGCA GAGAGAGGAC TGATCTAAAG AAATCGCCGT CTACTTCGAG CCTTTATGGT 3300

AAGAAGCTTT CAAACGGCTC AGTTGTGCCC TTGGAGGAAA GCTTGAATCT CATTGAAGTT 3360

GCCAACGAAG CCCCCAAGAA GAAAACGGGG TATTTTGCTG CCCCAGCTCA GCTGGATCCT 3420

GAGGACCAAT TCATTGTGCC TCCCGACTTG GAGGAGGAGG TGAGGGAGCA AATCAAGCAG 3480

CATCAGGAGC AGATCAGCGA GTCGGCAGCC AACCGGGAGA GCAGGACTGT CCTGACAGAG 3540

GTGTACGACA CCGCGTTATA A 3561

Domain Profile

S: 2     lvgvvsvngrrnemedavtsspnflkspekkdrlaffgvyDGhggsevakfcseklheil  61

         ++g++++ g++n+++ +v +++nf +  e+     ++g++DG++++ev + +++++ ++l

Q: 644   NHGFAEMAGQKNKLCVSVLAVDNFTDGVEA-----LYGMFDGDKNEEVPRLLQCTMGDVL  698

         789**********************98775.....9************************

S: 62    aeelesseseerkvkkalakaFlstdeelkvleeksldidksGstavvalikds......  115

          ee++    ++     +++++Fl  +++l       ++ +k Gs+a++++i+++

Q: 699   SEEVQ----QSSVDAVYMTNTFLVSHRKL------GMSGQKLGSSALLCYIRHDpsdsgs  748

         ***99....33333457************......889**************9999****

S: 116   ..klyvanvGdSravLcrngkavelssdHkpsre.dEleRieeaggsvilkdgaRvlGvL  172

           +++ anvG ++avLcr+g++++ls+ ++ ++  +E +R++ +++ +++++  +v+Gv+

Q: 749   yfSVTQANVGTCQAVLCRDGQPLPLSRVFSLENCnEETQRVKLQKAIITEDN--KVNGVT  806

         999999************************9875499********9999998..******

S: 173   avsRalGdlylkpyvtpePevtshrltsedefliLasDGlwdvvsneeavslvrdvlekk  232

         ++sR lG++yl+p+v p+P+v+ ++lt++d+ l+L+   lw+++s +ea+++v+++ +

Q: 807   CCSRQLGCTYLHPWVLPTPHVHTVPLTPQDDLLVLGNRALWEYLSYKEAIAAVQNMPD--  864

         **********************************************************..

S: 233   eaeqeaakkLvklalargskdnvsaivv  260

           +++aakkL++la+++g++dnv a+vv

Q: 865   --PKAAAKKLCTLAQSYGCRDNVGAVVV  890

         ..***********************997

Domain Sequence
(FASTA)

NHGFAEMAGQ KNKLCVSVLA VDNFTDGVEA LYGMFDGDKN EEVPRLLQCT MGDVLSEEVQ 60

QSSVDAVYMT NTFLVSHRKL GMSGQKLGSS ALLCYIRHDP SDSGSYFSVT QANVGTCQAV 120

LCRDGQPLPL SRVFSLENCN EETQRVKLQK AIITEDNKVN GVTCCSRQLG CTYLHPWVLP 180

TPHVHTVPLT PQDDLLVLGN RALWEYLSYK EAIAAVQNMP DPKAAAKKLC TLAQSYGCRD 240

NVGAVVV 247

Keyword

Complete proteome; Leucine-rich repeat; Reference proteome; Repeat.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>