EKS-LAC-00068

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-LAC-00068

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDK	369.0	1.7E-110	135	419	285

Status

Unreviewed

Ensembl Protein

ENSLACP00000005784

UniProt Accession

H3A813;

Protein Name

Protein Synonyms/Alias

Gene Name

CDK14

Gene Synonyms/Alias

CDK14;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSLACG00000005134	ENSLACP00000005784	ENSLACT00000005834

Organism

Latimeria chalumnae

Functional Description

Protein Length

469

Protein Sequence
(FASTA)

MCDLLAAQPS EKISRMKKLR RTLSESFSRI ALKKDDSTLD EICVTKMSTR NCQGMDSVIK 60

PLDTIPEDKK VRVQRTQSSF DPFEKPANQV KRVHSENNAC INFKSSSTGK ESPKFRRHSS 120

PSSPTSPKFG KADSYEKLEK LGEGSYATVY KGKSKVNGKL VALKVIRLQE EEGTPFTAIR 180

EASLLKGLKH ANIVLLHDII HTKETLTLVF EYVHTDLCQY MDKHPGGLHP ENVKLFLFQL 240

LRGLSYIHQR FILHRDLKPQ NLLISDTGEL KLADFGLARA KSVPSHTYSN EVVTLWYRPP 300

DVLLGSTEYS TCLDMWGVGC IFVEMIQGVA AFPGMKDIQD QLERIFLVLG TPSEESWPGV 360

YALPHFKPER FTQYSSKKLR QAWNKLDYVN HAEDLASKLL QCFPKNRLSA QAALNHEYFS 420

DLPPRLWELT DMSSIFTALN VKLQPETGDS MRVYGKNNCH SKGLSNNKH 469

Nucleotide Sequence
(FASTA)

ATGTGTGACC TGCTTGCAGC GCAGCCCAGT GAGAAAATCA GCAGGATGAA AAAGTTGAGG 60

CGAACTTTAT CGGAAAGTTT CAGTCGAATA GCCTTGAAGA AAGATGATAG CACCTTGGAT 120

GAGATATGTG TCACAAAGAT GTCTACACGG AACTGCCAGG GAATGGATTC AGTGATAAAA 180

CCCCTGGACA CGATTCCTGA AGATAAGAAG GTCAGGGTTC AAAGGACACA GAGCAGTTTT 240

GACCCATTTG AGAAACCAGC TAATCAAGTG AAAAGAGTCC ACTCCGAAAA CAATGCTTGT 300

ATTAACTTTA AGAGCTCATC TACTGGAAAA GAATCCCCTA AGTTCAGACG GCACTCAAGC 360

CCAAGTTCGC CCACAAGCCC CAAGTTTGGG AAAGCAGATT CCTACGAAAA ACTGGAAAAA 420

CTAGGTGAGG GGTCATATGC CACTGTATAC AAGGGAAAAA GCAAAGTAAA TGGAAAGTTA 480

GTGGCATTAA AAGTAATCAG GCTGCAAGAA GAAGAAGGTA CTCCATTTAC AGCTATTAGA 540

GAAGCTTCAC TTCTGAAAGG ACTGAAACAT GCTAATATTG TGCTGCTTCA TGACATCATT 600

CACACTAAAG AAACATTAAC GCTTGTCTTT GAGTATGTGC ACACTGATTT ATGCCAGTAC 660

ATGGACAAAC ACCCAGGAGG TCTTCATCCA GAAAACGTAA AGTTATTTTT GTTTCAGTTG 720

TTACGAGGGT TGTCTTATAT TCACCAACGA TTCATTTTAC ACAGAGACTT GAAGCCTCAA 780

AACCTGCTAA TCAGTGACAC TGGAGAGTTA AAACTAGCAG ACTTCGGCCT TGCCAGAGCA 840

AAGTCAGTTC CCAGCCACAC TTACTCTAAT GAAGTGGTAA CCCTGTGGTA CAGACCTCCA 900

GATGTCCTTT TGGGCTCCAC GGAGTACTCC ACTTGCCTTG ACATGTGGGG AGTTGGATGC 960

ATCTTCGTAG AAATGATTCA AGGAGTTGCT GCTTTTCCAG GAATGAAAGA TATTCAAGAC 1020

CAGCTGGAGC GAATATTTCT GGTTCTCGGC ACTCCATCTG AGGAGTCTTG GCCTGGCGTA 1080

TATGCCCTAC CACATTTCAA ACCAGAACGC TTTACACAGT ACAGCTCAAA AAAGCTCAGA 1140

CAAGCCTGGA ATAAGCTAGA CTACGTGAAT CACGCAGAGG ATCTGGCCTC CAAACTTCTA 1200

CAGTGCTTCC CAAAAAATAG ACTGTCAGCC CAGGCAGCCC TGAATCATGA GTACTTCAGC 1260

GATCTCCCCC CACGGCTCTG GGAACTGACT GACATGTCTT CTATTTTCAC TGCGCTGAAT 1320

GTGAAACTGC AACCTGAGAC TGGGGACAGC ATGAGGGTTT ATGGGAAAAA CAATTGTCAT 1380

AGCAAAGGCC TATCTAATAA CAAACACTGA 1410

Domain Profile

S: 1     yeklekigeGtygkvykakdketgevvAlKkirlekekegvpitalrEisllkelkhkni  60

         yeklek+geG+y++vyk+k+k +g++vAlK irl++e eg p+ta+rE sllk lkh+ni

Q: 135   YEKLEKLGEGSYATVYKGKSKVNGKLVALKVIRLQEE-EGTPFTAIREASLLKGLKHANI  193

         99********************************998.9*********************

S: 61    vkLlevvakdkkklyLvfefleqdLkkllkkkkkkklsleevkslllqlleglaylHsnk  120

         v L+++++ +k++l+Lvfe++++dL ++++k++  +l++e+vk +l+qll+gl+y+H++

Q: 194   VLLHDIIH-TKETLTLVFEYVHTDLCQYMDKHPG-GLHPENVKLFLFQLLRGLSYIHQRF  251

         ********.99***********************.*************************

S: 121   ilHRDlKpqNlLiskegklklaDfGlarafssplktytkevvTlwYraPelLlgakeYst  180

         ilHRDlKpqNlLis++g+lklaDfGlara s+p++ty++evvTlwYr+P++Llg++eYst

Q: 252   ILHRDLKPQNLLISDTGELKLADFGLARAKSVPSHTYSNEVVTLWYRPPDVLLGSTEYST  311

         ************************************************************

S: 181   avDiWsvgcilaelltrkplfqgkse.idqlerifkllgtpsekvwpevsklpeyk.ksf  238

          +D+W+vgci++e+++  + f+g ++ +dqlerif +lgtpse++wp+v  lp++k ++f

Q: 312   CLDMWGVGCIFVEMIQGVAAFPGMKDiQDQLERIFLVLGTPSEESWPGVYALPHFKpERF  371

         ************************99679***************************99**

S: 239   pkkkkkklkekvkklk..ekaldllekllaldpkkRisakealqhkyf  284

         +++++kkl++ ++kl+  ++a dl +kll++ pk+R+sa++al+h+yf

Q: 372   TQYSSKKLRQAWNKLDyvNHAEDLASKLLQCFPKNRLSAQAALNHEYF  419

         **************998778***************************9

Domain Sequence
(FASTA)

YEKLEKLGEG SYATVYKGKS KVNGKLVALK VIRLQEEEGT PFTAIREASL LKGLKHANIV 60

LLHDIIHTKE TLTLVFEYVH TDLCQYMDKH PGGLHPENVK LFLFQLLRGL SYIHQRFILH 120

RDLKPQNLLI SDTGELKLAD FGLARAKSVP SHTYSNEVVT LWYRPPDVLL GSTEYSTCLD 180

MWGVGCIFVE MIQGVAAFPG MKDIQDQLER IFLVLGTPSE ESWPGVYALP HFKPERFTQY 240

SSKKLRQAWN KLDYVNHAED LASKLLQCFP KNRLSAQAAL NHEYF 285

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Anolis carolinensis"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Tarsius syrichta"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013