EKS-LAC-00169

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-LAC-00169

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/RSKb	497.1	1.2E-149	390	647	258

Status

Unreviewed

Ensembl Protein

ENSLACP00000006372

UniProt Accession

H3A9Q1;

Protein Name

Protein Synonyms/Alias

Gene Name

RPS6KA3

Gene Synonyms/Alias

RPS6KA3;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSLACG00000005654	ENSLACP00000006372	ENSLACT00000006425

Organism

Latimeria chalumnae

Functional Description

Protein Length

709

Protein Sequence
(FASTA)

LVESSCPPAQ EEDGIKEIAI THHVKEGHDK ADPSQFELLK VLGQGSFGKV FLVRKISGPD 60

AGYLYAMKVL KKATLKVRDR VRTKMERDIL VEVNHPFIVK LHYAFQTEGK LYLILDFLRG 120

GDLFTRLSKE IKFFSNEVKR WLYEKIIFGD SLLTYTITKR VLNVNIILLD EDGHIKLTDF 180

GLSKESIDHE RKAYSFCGTV EYMAPEVVNR RGHTQSADWW SFGVLMFEML TGTLPFQGKD 240

RKETMTMILK AKLGMPQFLS AEAQSLLRML FKRNPANRLG AGPDGVEEIK RHAFFATIDW 300

NKLYRRETPP PFKPATGRPD DTFYFDSEFT AKTPKGKILI SPELKPEMLL KKWSFITVES 360

ESLFEARIVL SILDDVKQLH RNSIQFTDGY EVKEDIGVGS YSICKRCIHK ATNMEYAVKI 420

IDKSKRDPSE EIEILLRYGQ HPNIITLKDV YDDGKYVYLV TELMKGGELL DKILRQKFFS 480

EREASAVLFT ITKTVEYLHT QGVVHRDLKP SNILYVDESG NPESIRICDF GFAKQLRAEN 540

GLLMTPCYTA NFVAPEVLKR QGYDAACDIW SLGVLLYTML TGYTPFANGP DDTPEDILAR 600

IGSGKFSLSG GYWNSVSDEA KDLVSKMLHV DPHQRLTAAL VLRHSWIVHR DKLPQFQLNR 660

QDAPHLVKGA MAATYSALNR NPLTPVLEPV GCSTLAQRRG VKKLTSTAL 709

Nucleotide Sequence
(FASTA)

TTAGTTGAAT CAAGTTGCCC ACCAGCCCAG GAGGAAGACG GTATCAAAGA GATAGCAATC 60

ACACACCATG TGAAAGAAGG GCATGACAAA GCAGATCCTT CTCAGTTTGA GCTGCTTAAA 120

GTCTTGGGCC AGGGATCATT TGGAAAGGTG TTTCTTGTAA GAAAGATTTC TGGGCCTGAT 180

GCTGGGTATC TGTATGCAAT GAAAGTGCTT AAGAAAGCCA CACTTAAAGT TCGTGACCGT 240

GTTCGGACGA AAATGGAACG TGACATACTT GTGGAAGTTA ATCATCCCTT CATTGTAAAA 300

TTGCACTATG CTTTTCAGAC AGAAGGCAAA CTATATCTTA TTCTGGATTT TCTCAGGGGA 360

GGAGATTTAT TCACTCGCTT ATCCAAAGAG ATAAAATTTT TTTCAAACGA AGTTAAAAGG 420

TGGCTATATG AAAAAATAAT TTTTGGTGAC AGCTTATTGA CCTATACAAT TACTAAGAGG 480

GTATTAAATG TAAATATTAT TCTGCTTGAT GAAGATGGAC ATATAAAATT AACAGATTTT 540

GGTTTGAGTA AAGAGTCTAT TGACCATGAG AGGAAGGCCT ATTCGTTTTG TGGTACTGTA 600

GAGTACATGG CACCTGAAGT TGTTAACCGA CGAGGACACA CTCAGAGTGC AGACTGGTGG 660

TCTTTTGGTG TTCTTATGTT TGAGATGCTG ACAGGTACAT TGCCATTTCA AGGAAAAGAC 720

CGGAAGGAGA CAATGACTAT GATACTTAAA GCAAAGCTTG GAATGCCTCA GTTTTTAAGT 780

GCAGAAGCTC AGAGTCTCTT ACGAATGTTG TTCAAACGGA ACCCCGCAAA CAGATTAGGT 840

GCTGGTCCAG ATGGAGTTGA AGAAATAAAG AGACATGCAT TCTTTGCTAC AATAGACTGG 900

AATAAATTGT ACAGAAGAGA AACACCACCA CCTTTTAAAC CTGCCACTGG CAGACCAGAT 960

GATACCTTCT ATTTTGATTC AGAGTTCACT GCAAAAACAC CAAAAGGTAA GATCTTGATT 1020

TCTCCTGAAT TAAAACCAGA AATGCTGCTC AAGAAATGGT CCTTTATCAC AGTTGAAAGT 1080

GAATCCCTTT TTGAAGCTAG AATAGTGTTG AGTATTTTAG ATGATGTGAA GCAATTACAC 1140

AGAAACAGTA TCCAGTTTAC AGATGGGTAT GAAGTGAAAG AAGATATTGG AGTGGGTTCT 1200

TACTCTATCT GCAAGCGATG CATTCACAAA GCAACCAATA TGGAATATGC TGTAAAGATA 1260

ATTGACAAGA GCAAGCGAGA TCCTTCAGAA GAGATTGAGA TACTTCTGCG CTATGGACAA 1320

CATCCAAATA TCATTACGTT AAAGGATGTG TATGATGATG GCAAGTACGT GTACCTAGTG 1380

ACAGAGCTCA TGAAAGGAGG GGAACTTCTG GACAAAATTC TCAGGCAAAA ATTTTTCTCT 1440

GAACGAGAGG CTAGTGCTGT CCTTTTCACT ATAACAAAAA CCGTGGAATA CCTTCACACA 1500

CAAGGGGTAG TGCACAGAGA CCTAAAACCC AGTAACATTC TGTACGTGGA TGAATCTGGC 1560

AACCCAGAAT CCATTCGAAT CTGTGACTTT GGCTTTGCAA AGCAGTTGAG AGCAGAGAAT 1620

GGTCTATTGA TGACTCCATG TTATACAGCT AATTTTGTTG CTCCAGAGGT CTTGAAAAGG 1680

CAAGGCTATG ATGCTGCATG TGACATCTGG AGTTTGGGTG TTCTTCTCTA CACCATGCTC 1740

ACTGGGTATA CCCCATTTGC CAATGGTCCT GATGACACTC CAGAAGATAT TTTAGCACGA 1800

ATAGGAAGCG GCAAGTTCTC TCTAAGTGGA GGGTACTGGA ATTCAGTTTC AGATGAAGCT 1860

AAGGACCTGG TATCAAAGAT GCTCCATGTT GATCCTCACC AACGACTGAC TGCTGCGCTG 1920

GTGCTCCGAC ACTCCTGGAT TGTTCACAGA GACAAGTTGC CACAGTTCCA GCTAAACAGA 1980

CAAGATGCCC CCCACCTGGT TAAGGGTGCA ATGGCAGCCA CATATTCAGC CCTGAACCGC 2040

AATCCATTAA CACCAGTTCT GGAACCGGTT GGCTGCTCTA CGCTGGCTCA GCGGAGAGGT 2100

GTTAAAAAGC TAACTTCAAC AGCCCTTTAA 2130

Domain Profile

S: 1     yevkedlGvGsysvckrcvhkatnqefavkiidkskrdtseeieillryeqhpnivtlkd  60

         yevked+GvGsys+ckrc+hkatn+e+avkiidkskrd+seeieillry+qhpni+tlkd

Q: 390   YEVKEDIGVGSYSICKRCIHKATNMEYAVKIIDKSKRDPSEEIEILLRYGQHPNIITLKD  449

         789*********************************************************

S: 61    vyddgkyvylvlellkGGelldrikkkkffsereasailrtlvkaveylheqGvvhrdlk  120

         vyddgkyvylv+el+kGGelld+i+++kffsereasa+l+t++k+veylh+qGvvhrdlk

Q: 450   VYDDGKYVYLVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEYLHTQGVVHRDLK  509

         ************************************************************

S: 121   penilyvdesdnaesikiidfGfaklkraengllktpcytlnfvapevlkrqGydeacdl  180

         p+nilyvdes+n+esi+i+dfGfak++raengll+tpcyt+nfvapevlkrqGyd+acd+

Q: 510   PSNILYVDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGYDAACDI  569

         ************************************************************

S: 181   wslGvllytmlaGyvpfangpedtaeeilakikeGkfslsGeawdsvseeakdlvskllt  240

         wslGvllytml+Gy+pfangp+dt+e+ila+i++GkfslsG++w+svs+eakdlvsk+l+

Q: 570   WSLGVLLYTMLTGYTPFANGPDDTPEDILARIGSGKFSLSGGYWNSVSDEAKDLVSKMLH  629

         ************************************************************

S: 241   vdpakrlkleqllkhswl  258

         vdp++rl+++ +l+hsw+

Q: 630   VDPHQRLTAALVLRHSWI  647

         *****************8

Domain Sequence
(FASTA)

YEVKEDIGVG SYSICKRCIH KATNMEYAVK IIDKSKRDPS EEIEILLRYG QHPNIITLKD 60

VYDDGKYVYL VTELMKGGEL LDKILRQKFF SEREASAVLF TITKTVEYLH TQGVVHRDLK 120

PSNILYVDES GNPESIRICD FGFAKQLRAE NGLLMTPCYT ANFVAPEVLK RQGYDAACDI 180

WSLGVLLYTM LTGYTPFANG PDDTPEDILA RIGSGKFSLS GGYWNSVSDE AKDLVSKMLH 240

VDPHQRLTAA LVLRHSWI 258

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0000287	; F:magnesium ion binding
GO:0004674	; F:protein serine/threonine kinase activity
GO:0007243	; P:intracellular protein kinase cascade

KEGG

InterPros

IPR000961	; AGC-kinase_C.
IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR016239	; Ribosomal_S6_kinase_II.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 2.

SMARTs

SM00133	; S_TK_X; 1.
SM00220	; S_TKc; 2.

Prosites

PS51285	; AGC_KINASE_CTER; 1.
PS00107	; PROTEIN_KINASE_ATP; 2.
PS50011	; PROTEIN_KINASE_DOM; 2.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013